Núria López-Bigas - Publications, H-index & Citations

Núria López-Bigas

Institute for Research in Biomedicine

78H指数

423论文数

4.4W被引数

收录论文 122

发表时间

Deep molecular profiling of lung neuroendocrine tumours and supra-carcinoids 肺神经内分泌肿瘤和类癌的深层分子谱分析

Molecular Cancer

IF33.9

2026-08-27

OAAI

Alexandra Sexton-Oates; Émilie Mathian; Noah Candeli; Yuliya Lim; Catherine Voegele; Alex Di Genova; Laurane Mangé; Zhaozhi Li; Tijmen van Weert; Lipika Kalson; Tiffany M. Delhomme; Lisa M. Hillen; Ricardo Blázquez-Encinas; Abel Gonzalez-Perez; Maike L. Morrison; Eleonora Lauricella; Lise Mangiante; Lisa Bonheme; Laura Moonen; Gudrun Absenger; Janine Altmuller; Cyril Degletagne; Odd Terje Brustugun; Vincent Cahais; Giovanni Centonze; Amélie Chabrier; Cyrille Cuenin; Francesca Damiola; Vincent Thomas de Montpréville; Jean-François Deleuze; Anne-Marie C. Dingemans; Élie Fadel; Nicolas Gadot; Akram Ghantous; Paolo Graziano; Paul Hofman; Véronique Hofman; Alejandro Ibáñez-Costa; Stéphanie Lacomme; Nuria Lopez-Bigas; Marius Lund-Iversen; Massimo Milione; Lucia Anna Muscarella; Sergio Pedraza-Arevalo; Corinne Perrin; Gaetane Planchard; Helmut Popper; Luca Roz; Angelo Sparaneo; Wieneke Buikhuisen; José van den Berg; Margot Tesselaar; Jaehee Kim; Ernst Jan M. Speel; Séverine Tabone-Eglinger; Thomas Walter; Gavin M. Wright; Justo P. Castaño; Lara Chalabreysse; Liming Chen; Christophe Caux; Marco Volante; Nicolas Girard; Jean-Michel Vignaud; Esther Conde; Audrey Mansuet-Lupo; Luka Brcic; Giuseppe Pelosi; Mauro Giulio Papotti; Sylvie Lantuejoul; Jules Derks; Talya Dayton; Nicolas Alcala; Matthieu Foll; Lynnette Fernandez-Cuesta

Genetic background sets the trajectory of experimental cancer evolution 遗传背景决定了实验性癌症进化的轨迹

Nature

IF48.5

2026-07-22

OAAI

Sarah J. Aitken; Frances Connor; Christine Feig; Tim F. Rayner; Margus Lukk; Juliet Luft; Stuart Aitken; Claudia Arnedo-Pac; James F. Hayes; Michael D. Nicholson; Ailith Ewing; Vasavi Sundaram; Jan C. Verburg; John Connelly; Craig J. Anderson; Mikaela Behm; Susan Campbell; Maëlle Daunesse; Vera B. Kaiser; Elissavet Kentepozidou; Oriol Pich; Aisling M. Redmond; Javier Santoyo-Lopez; Inés Sentís; Lana Talmane; Paul Flicek; Núria López-Bigas; Colin A. Semple; Martin S. Taylor; Duncan T. Odom

Chemically induced skin tumors arise from long-lived stem cells of the upper hair follicle 化学诱导的皮肤肿瘤起源于上毛囊的长寿命干细胞

Science

IF45.8

2026-06-11

PREAI

Eve Kandyba; Arnaud Jabouille; Ferriol Calvet; Yun Rose Li; Andrea Curtabbi; Diana Cristea; Joyce Shin; Reyno Delrosario; Jonathan Anzules; Di Wu; David Quigley; Mark Taylor; Camila Zanette; Fang Yin Lo; Jacob Higgins; Jesse Salk; Nuria Lopez-Bigas; Allan Balmain

Tumour promotion through the lens of evolution 肿瘤促进：进化视角

Nature

IF48.5

2026-04-15

PREAI

Nuria Lopez-Bigas; Eve Kandyba; Abel Gonzalez-Perez; Paul Brennan; Allan Balmain

Evaluation of BoostDM, a somatic variant prediction tool, for the interpretation of germline variants in hereditary cancer genes 对BoostDM这一体细胞变异预测工具在解读遗传性癌基因中的生殖细胞变异方面的评估

European Journal of Human Genetics

IF4.6

2026-03-16

OAAI

Elisabet Munté; Ferran Muiños; Raúl Marín; Lidia Feliubadaló; Federica Brando; Núria López-Bigas; Conxi Lázaro; Abel González-Pérez; Laura Valle

Sex and smoking bias in the selection of somatic mutations in human bladder 人类膀胱体细胞突变选择中的性别与吸烟偏倚

Nature

IF48.5

2025-10-08

OAAI

Ferriol Calvet; Raquel Blanco Martinez-Illescas; Ferran Muiños; Maria Tretiakova; Elena S. Latorre-Esteves; Jeanne Fredrickson; Maria Andrianova; Stefano Pellegrini; Axel Rosendahl Huber; Joan Enric Ramis-Zaldivar; Shuyi Charlotte An; Elana Thieme; Brendan F. Kohrn; Miguel L. Grau; Abel Gonzalez-Perez; Nuria Lopez-Bigas; Rosa Ana Risques

Oncodrive3D: fast and accurate detection of structural clusters of somatic mutations under positive selection

NUCLEIC ACIDS RESEARCH

IF13.1

2025-08-28

PREAI

Pellegrini, Stefano; Dove-Estrella, Olivia; Muinos, Ferran; Lopez-Bigas, Nuria; Gonzalez-Perez, Abel

Five latent factors underlie response to immunotherapy 免疫疗法反应的五个潜在因素

NATURE GENETICS

IF31.8

2024-09-12

OAAI

Usset, Joseph; Huber, Axel Rosendahl; Andrianova, Maria A.; Batlle, Eduard; Carles, Joan; Cuppen, Edwin; Elez, Elena; Felip, Enriqueta; Gomez-Rey, Marina; Lo Giacco, Deborah; Martinez-Jimenez, Francisco; Munoz-Couselo, Eva; Siu, Lillian L.; Tabernero, Josep; Vivancos, Ana; Muinos, Ferran; Gonzalez-Perez, Abel; Lopez-Bigas, Nuria

Cancer genome interpreter: A data-driven tool for tumor mutation interpretation 癌症基因组解释器：一个用于肿瘤突变解释的数据驱动工具

ANNALS OF ONCOLOGY

IF65.4

2024-09-01

PREAI

Demajo, S.; Tort, O.; Sanchez-Guixe, M.; Muinos, F.; Rosa, P. Gomis; Lopez-Elorduy, C.; Fernandez, M. Guardiola; Brando, F.; Grau, M.; Deu-Pons, J.; Gonzalez-Perez, A.; Lopez-Bigas, N.

Heterologous mRNA/MVA delivering trimeric-RBD as effective vaccination regimen against SARS-CoV-2: COVARNA Consortium

EMERGING MICROBES & INFECTIONS

IF7.5

2024-08-08

OAAI

Marcos-Villar, Laura; Perdiguero, Beatriz; Lopez-Bravo, Maria; Zamora, Carmen; Sin, Laura; Alvarez, Enrique; Sorzano, Carlos oscar S.; Sanchez-Cordon, Pedro J.; Casasnovas, Jose M.; Astorgano, David; Garcia-Arriaza, Juan; Anthiya, Shubaash; Borrajo, Mireya L.; Lou, Gustavo; Cuesta, Belen; Franceschini, Lorenzo; Gelpi, Josep L.; Thielemans, Kris; Sistere-Oro, Marta; Meyerhans, Andreas; Garcia, Felipe; Esteban, Ignasi; Lopez-Bigas, Nuria; Plana, Montserrat; Alonso, Maria J.; Esteban, Mariano; Gomez, Carmen Elena

Implications of noncoding regulatory functions in the development of insulinomas

CELL GENOMICS

IF9

2024-08-01

OAAI

Ramos-Rodriguez, Mireia; Subirana-Granes, Marc; Norris, Richard; Sordi, Valeria; Fernandez, Angel; Fuentes-Paez, Georgina; Perez-Gonzalez, Beatriz; Balaguer, Clara Berenguer; Raurell-Vila, Helena; Chowdhury, Murad; Corripio, Raquel; Partelli, Stefano; Lopez-Bigas, Nuria; Pellegrini, Silvia; Montanya, Eduard; Nacher, Montserrat; Falconi, Massimo; Layer, Ryan; Rovira, Meritxell; Gonzalez-Perez, Abel; Piemonti, Lorenzo; Pasquali, Lorenzo

Modulating the immune response to SARS-CoV-2 by different nanocarriers delivering an mRNA expressing trimeric RBD of the spike protein: COVARNA Consortium (vol 9, 53, 2024)

NPJ VACCINES

IF6.5

2024-05-18

OAAI

Marcos-Villar, Laura; Perdiguero, Beatriz; Anthiya, Shubaash; Borrajo, Mireya L.; Lou, Gustavo; Franceschini, Lorenzo; Esteban, Ignasi; Sanchez-Cordon, Pedro J.; Zamora, Carmen; Sorzano, Carlos Oscar S.; Jorda, Luis; Codo, Laia; Gelpi, Josep L.; Sistere-Oro, Marta; Meyerhans, Andreas; Thielemans, Kris; Martinez-Jimenez, Francisco; Lopez-Bigas, Nuria; Garcia, Felipe; Alonso, Maria J.; Plana, Montserrat; Esteban, Mariano; Elena Gomez, Carmen

Identification of Clonal Hematopoiesis Driver Mutations through In Silico Saturation Mutagenesis 通过计算机饱和诱变鉴定克隆造血驱动突变

CANCER DISCOVERY

IF33.3

2024-05-09

OAAI

Demajo, Santiago; Ramis-Zaldivar, Joan E.; Muinos, Ferran; Grau, Miguel L.; Andrianova, Maria; Lopez-Bigas, Nuria; Gonzalez-Perez, Abel

The 1+Million Genomes Minimal Dataset for Cancer 癌症的100万个基因组最小数据集

NATURE GENETICS

IF31.8

2024-05-03

PREAI

Riba, Michela; Sala, Cinzia; Culhane, Aedin C.; Flobak, Asmund; Patocs, Attila; Boye, Kjetil; Plevova, Karla; Pospisilova, Sarka; Gandolfi, Giorgia; Morelli, Marco J.; Bucci, Gabriele; Edsjo, Anders; Lassen, Ulrik; Al-Shahrour, Fatima; Lopez-Bigas, Nuria; Hovland, Randi; Cuppen, Edwin; Valencia, Alfonso; Poirel, Helene A.; Rosenquist, Richard; Scollen, Serena; Marquez, Juan Arenas; Belien, Jeroen; De Nicolo, Arcangela; De Maria, Ruggero; Torrents, David; Tonon, Giovanni

Genomic deletions explain the generation of alternative BRAF isoforms conferring resistance to MAPK inhibitors in melanoma

CELL REPORTS

IF6.9

2024-04-01

OAAI

Aya, Francisco; Lanuza-Gracia, Pablo; Gonzalez-Perez, Abel; Bonnal, Sophie; Mancini, Estefania; Lopez-Bigas, Nuria; Arance, Ana; Valcarcel, Juan

Origins of Second Malignancies in Children and Mutational Footprint of Chemotherapy in Normal Tissues 儿童第二恶性肿瘤的起源和正常组织中化疗的突变足迹

CANCER DISCOVERY

IF33.3

2024-03-19

OAAI

Sanchez-Guixe, Monica; Muinos, Ferran; Pinheiro-Santin, Morena; Gonzalez-Huici, Victor; Rodriguez-Hernandez, Carlos J.; Avgustinova, Alexandra; Lavarino, Cinzia; Gonzalez-Perez, Abel; Mora, Jaume; Lopez-Bigas, Nuria

Assessment of Human SARS CoV-2-Specific T-Cell Responses Elicited In Vitro by New Computationally Designed mRNA Immunogens (COVARNA)

VACCINES

IF3.4

2023-12-22

OAAI

Esteban, Ignasi; Pastor-Quinones, Carmen; Usero, Lorena; Aurrecoechea, Elena; Franceschini, Lorenzo; Esprit, Arthur; Gelpi, Josep Lluis; Martinez-Jimenez, Francisco; Lopez-Bigas, Nuria; Breckpot, Karine; Thielemans, Kris; Leal, Lorna; Gomez, Carmen Elena; Sistere-Oro, Marta; Meyerhans, Andreas; Esteban, Mariano; Alonso, Maria Jose; Garcia, Felipe; Plana, Montserrat

Hotspot propensity across mutational processes 跨突变过程的热点倾向

MOLECULAR SYSTEMS BIOLOGY

IF7.7

2023-12-20

OAAI

Arnedo-Pac, Claudia; Muinos, Ferran; Gonzalez-Perez, Abel; Lopez-Bigas, Nuria

Cancer Evolution: A Multifaceted Affair 癌症进化: 一个多方面的事件

CANCER DISCOVERY

IF33.3

2023-12-06

OAAI

Ciriello, Giovanni; Magnani, Luca; Aitken, Sarah J.; Akkari, Leila; Behjati, Sam; Hanahan, Douglas; Landau, Dan A.; Lopez-Bigas, Nuria; Lupianez, Dario G.; Marine, Jean-Christophe; Martin-Villalba, Ana; Natoli, Gioacchino; Obenauf, Anna C.; Oricchio, Elisa; Scaffidi, Paola; Sottoriva, Andrea; Swarbrick, Alexander; Tonon, Giovanni; Vanharanta, Sakari; Zuber, Johannes

Mutational signature dynamics shaping the evolution of oesophageal adenocarcinoma 影响食管腺癌演变的突变特征动力学

NATURE COMMUNICATIONS

IF15.7

2023-07-15

OAAI

Abbas, Sujath; Pich, Oriol A.; Devonshire, Ginny; Zamani, Shahriar; Katz-Summercorn, Annalise; Killcoyne, Sarah; Cheah, Calvin; Nutzinger, Barbara; Grehan, Nicola; Lopez-Bigas, Nuria; Edwards, Paul A. W.; Fidziukiewicz, Elwira M.; Redmond, Aisling; Freeman, Adam C.; Smyth, Elizabeth; O'Donovan, Maria; Miremadi, Ahmad; Malhotra, Shalini; Tripathi, Monika; Coles, Hannah; Flint, Conor; Eldridge, Matthew; Jammula, Sriganesh; Davies, Jim; Crichton, Charles; Carroll, Nick H.; Hardwick, Richard; Safranek, Peter; Hindmarsh, Andrew; Sujendran, Vijayendran J.; Hayes, Stephen; Ang, Yeng; Sharrocks, Andrew R.; Preston, Shaun; Bagwan, Izhar; Save, Vicki; Skipworth, Richard J. E. R.; Hupp, Ted; O'Neill, J. Robert; Tucker, Olga; Beggs, Andrew; Taniere, Philippe; Puig, Sonia; Contino, Gianmarco J.; Underwood, Timothy C.; Walker, Robert L.; Grace, Ben; Lagergren, Jesper; Gossage, James; Davies, Andrew; Chang, Fuju; Mahadeva, Ula; Goh, Vicky D.; Ciccarelli, Francesca; Sanders, Grant; Berrisford, Richard; Chan, David; Cheong, Ed; Kumar, Bhaskar; Sreedharan, L. L.; Parsons, Simon; Soomro, Irshad; Kaye, Philip; Saunders, John; Lovat, Laurence; Haidry, Rehan; Scott, Michael; Sothi, Sharmila; Lishman, Suzy B.; Hanna, George J.; Peters, Christopher; Moorthy, Krishna; Grabowska, Anna; Turkington, Richard; McManus, Damian; Coleman, Helen D.; Petty, Russell; Bartlett, Freddie C.; Fitzgerald, Rebecca; Secrier, Maria

研究方向