Jarno Drost - Publications, H-index & Citations

Jarno Drost

university college london

34H指数

186论文数

1.1W被引数

收录论文 59

发表时间

Combined inhibition of de novo pyrimidine synthesis and ATR promotes ATF4-mediated cell death in TP53-deficient ALL 联合抑制嘧啶的从头合成和ATR促进TP53-deficient ALL的ATF4-mediated细胞死亡

HemaSphere

IF14.6

2026-07-28

OAAI

Kari J. T. Grünewald; Marjolein M. G. Kes; Gawin R. Stoll; Willem P. J. Cox; Dorette S. van Ingen Schenau; Enzo M. Scutigliani; Emmely M. Wagener; Ziqin Tang; Senna Visser; Jolanda Kooiman; Jessica Buijs-Gladdines; Maria Rodionova; Esther A. Zaal; Jeroen W. A. Jansen; Jeroen F. van Velzen; Jarno Drost; Laurens T. van der Meer; Celia R. Berkers; Frank N. van Leeuwen

Fusion-positive rhabdomyosarcoma oncofusions share a common interactome 融合阳性横纹肌肉瘤癌融合蛋白共享共同的相互作用组

Nature Communications

IF15.7

2026-05-28

OAAI

S. P. Zimmerman; C. D. Delaney; B. K. Lau; L. B. DeGraw; G. H. Rupprecht; M. J. A. Groot Koerkamp; T. de Souza; J. Drost; R. A. Schoot; M. T. Meister; J. F. Shern; L. M. Wagner; G. G. Wang; K. C. Wood; C. M. Linardic; C. M. Counter

Characteristics and outcome of patients with second and subsequent relapse of Wilms tumour-A report from the SIOP Renal Tumour Study Group Wilms肿瘤二线及后续复发的患者特征与预后——SIOP肾肿瘤研究组的报告

EJC Paediatric Oncology

IF0

2026-05-01

PREAI

Groenendijk, Alissa; Mavinkurve-Groothuis, Annelies M. C.; van Tinteren, Harm; de Krijger, Ronald R.; Al-Saadi, Reem; Pritchard-Jones, Kathy; Ramirez-Villar, Gema L.; Vujanic, Gordan; Melchior, Patrick; Godzinski, Jan; Schenk, Jens-Peter; Graf, Norbert; Segers, Heidi; Sudour-Bonnange, Helene; Verschuur, Arnauld C.; Drost, Jarno; Perotti, Daniela; Koenig, Christa; Spreafico, Filippo; Brok, Jesper; van den Heuvel-Eibrink, Marry M.

Protocol for lentiviral engineering and multi-omic characterization of human kidney tubuloids 人肾小管样组织的慢病毒工程化和多组学表征方案

STAR Protocols

IF1.3

2026-02-01

OAAI

Perticari, Giulia; Ganpat, Maroussia M. P.; Drost, Jarno

Relapsed rhabdoid tumours and other non-nephroblastoma childhood and adolescent kidney tumours: perspectives from the HARMONICA collaboration 复发性横纹肌样肿瘤和其他非肾母细胞瘤儿童和青少年肾脏肿瘤: 口琴合作的观点

Nature Reviews Urology

IF14.6

2026-01-02

PREAI

Michael V. Ortiz; Francis S.P.L. Wens; Andrew L. Hong; Paola Quarello; Arnauld C. Verschuur; Elisabeth T. Tracy; Najat C. Daw; Jeffrey S. Dome; Amy L. Walz; Julia Sprokkerieft; Godelieve A. M. Tytgat; Alex Kentsis; Jaime Libes-Bander; Peter J. Schoettler; Daniela Perotti; Jarno Drost; Rajkumar Venkatramani; James I. Geller; Marry M. van den Heuvel-Eibrink

A pathway-informed mutual exclusivity framework to detect genetic interactions in pediatric cancer 一种基于通路信息的互斥性框架，用于检测儿科癌症中的遗传相互作用

BMC MEDICAL GENOMICS

IF2

2025-12-12

PREAI

Spinou, Anastasia; Gremmen, Richard; Drost, Jarno; Kemmeren, Patrick

Organoids in pediatric cancer research 类器官在儿科癌症研究中的应用

FEBS Letters

IF3

2025-10-14

OAAI

Carla Ríos Arceo; Jarno Drost

A cycling, progenitor-like cell population at the base of atypical teratoid rhabdoid tumor subtype differentiation trajectories Blanco-Carmona, E.; Paassen, I.; He, J.; DeMartino, J.; Büllesbach, A.; Anderson, N.; Buhl, J.L.; Federico, A.; Mauermann, M.; Brok, M.; et al. 一种位于非典型畸胎样横纹肌样瘤亚型分化轨迹基部的、具有循环特性的祖细胞样细胞群体。神经肿瘤学，2025; 网络优先出版。 [Google Scholar] [CrossRef]

Neuro-Oncology

IF13.4

2025-09-01

OAAI

Blanco-Carmona, Enrique; Paassen, Irene; He, Jiayou; Demartino, Jeff; Bullesbach, Annette; Anderson, Nadia; Buhl, Juliane L.; Federico, Aniello; Mauermann, Monika; Brok, Mariel; Straathof, Karin; Behjati, Sam; Vibhakar, Rajeev; Donson, Andrew M.; Foreman, Nicholas K.; Shaw, Mckenzie; Fruhwald, Michael C.; Korshunov, Andrey; Hasselblatt, Martin; Thomas, Christian; Franke, Niels; Kranendonk, Mariette E. G.; Hoving, Eelco W.; Jaeger, Natalie; Johann, Pascal D.; Pfister, Stefan M.; Filbin, Mariella G.; Kool, Marcel; Drost, Jarno

Functional avidity of anti-B7H3 CAR-T constructs predicts antigen density thresholds for triggering effector function 抗B7H3 CAR-T构建体的功能亲合力预测触发效应功能的抗原密度阈值

Nature Communications

IF15.7

2025-08-05

OAAI

Marta Barisa; Henrike P. Muller; Elisa Zappa; Rivani Shah; Juliane L. Buhl; Benjamin Draper; Courtney Himsworth; Chantelle Bowers; Sophie Munnings-Tomes; Marilena Nicolaidou; Sonia Morlando; Kathleen Birley; Clara Leboreiro-Babe; Alice Vitali; Laura Privitera; Kyle O’Sullivan; Ailsa Greppi; Magdalena Buschhaus; Mario Barrera Román; Sam de Blank; Femke van den Ham; Brenna R. van ‘t Veld; Gabrielle Ferry; Jonathan Fisher; Debarati Shome; Reza Nadafi; Israrul H. Ansari; Rogier Reijmers; Stefano Giuliani; Paul Sondel; Laura K. Donovan; Louis Chesler; Jan Molenaar; Jarno Drost; Anne C. Rios; Kerry Chester; Judith Wienke; John Anderson

An engineered tumor organoid model reveals cellular identity and signaling trajectories underlying SFPQ-TFE3 driven translocation RCC 工程化肿瘤类器官模型揭示了SFPQ-TFE3驱动的易位性肾细胞癌（translocation RCC）中细胞身份和信号轨迹的潜在机制。

ISCIENCE

IF4.1

2025-04-01

OAAI

Ganpat, Maroussia M. P.; Morales-Rodriguez, Francisco; Pham, Nhung; Lijnzaad, Philip; de Souza, Terezinha; Derakhshan, Sepide; Fumagalli, Arianna; Zeller, Peter; Balwierz, Aleksandra; Ayyildiz, Dilara; van den Heuvel-Eibrink, Marry M.; de Krijger, Ronald R.; van Oudenaarden, Alexander; Margaritis, Thanasis; Lopes, Susana M. Chuva de Sousa; Drost, Jarno

Lactate controls cancer stemness and plasticity through epigenetic regulation 乳酸通过表观遗传调控控制癌症干性及可塑性

CELL METABOLISM

IF30.9

2025-02-01

OAAI

Nguyen, Nguyen T. B.; Gevers, Sira; Kok, Rutger N. U.; Burgering, Lotte M.; Neikes, Hannah; Akkerman, Ninouk; Betjes, Max A.; Ludikhuize, Marlies C.; Gulersonmez, Can; Stigter, Edwin C. A.; Vercoulen, Yvonne; Drost, Jarno; Clevers, Hans; Vermeulen, Michiel; van Zon, Jeroen S.; Tans, Sander J.; Burgering, Boudewijn M. T.; Colman, Maria J. Rodriguez

Complex structural variation is prevalent and highly pathogenic in pediatric solid tumors

CELL GENOMICS

IF9

2024-11-01

OAAI

Belzen, Ianthe A. E. M. van; van Tuil, Marc; Badloe, Shashi; Janse, Alex; Verwiel, Eugene T. P.; Santoso, Marcel; de Vos, Sam; Baker-Hernandez, John; Kerstens, Hindrik H. D.; Solleveld-Westerink, Nienke; Meister, Michael T.; Drost, Jarno; Heuvel-Eibrink, Marry M. van den; Merks, Johannes H. M.; Molenaar, Jan J.; Peng, Weng Chuan; Tops, Bastiaan B. J.; Holstege, Frank C. P.; Kemmeren, Patrick; Hehir-Kwa, Jayne Y.

Recapitulating the adenoma-carcinoma sequence by selection of four spontaneous oncogenic mutations in mismatch-repair-deficient human colon organoids 通过选择错配修复缺陷型人类结肠类器官中的四个自发致癌突变来重述腺瘤-癌序列

NATURE CANCER

IF28.5

2024-11-01

OAAI

Mizutani, Tomohiro; Boretto, Matteo; Lim, Sangho; Drost, Jarno; Gonzalez, Diego Montiel; Oka, Rurika; Geurts, Maarten H.; Begthel, Harry; Korving, Jeroen; van Es, Johan H.; van Boxtel, Ruben; Clevers, Hans

Bridging the gap: advancing cancer cell culture to reveal key metabolic targets

FRONTIERS IN ONCOLOGY

IF3.3

2024-09-17

OAAI

Kes, Marjolein M. G.; Berkers, Celia R.; Drost, Jarno

Somatic genetic development of Wilms tumor via normal kidneys in predisposed children 易感儿童通过正常肾脏进行Wilms肿瘤的体细胞遗传发育

CANCER RESEARCH

IF16.6

2024-09-05

PREAI

Treger, Taryn D.; Wegert, Jenny; Wenger, Anna; Coorens, Tim H. H.; Al-Saadi, Reem; Kemps, Paul; Kennedy, Jonathan; Parks, Conor; Anderson, Nathaniel D.; Hodder, Angus; Letunovska, Aleksandra; Jung, Hyunchul; Ogbonnah, Toochi; Mi Trinh; Lee-Six, Henry; Morcrette, Guillaume; van den Heuvel-Eibrink, Marry M.; Drost, Jarno; van Boxtel, Ruben; Bertrums, Eline; Goemans, Bianca; Jongmans, Marjolein; Kuiper, Roland; Antoniou, Evangelia; Reinhardt, Dirk; Bartram, Jack; Hutchinson, Ciaran; Vujanic, Gordan; Vokuhl, Christian; Chowdhury, Tanzina; Furtwangler, Rhoikos; Graf, Norbert; Gessler, Manfred; Behjati, Sam

MULTI-OMICS SEQUENCING OF ATYPICAL TERATOID RHABDOID TUMORS UNVEILS A SHARED GROUND-STATE POPULATION PROMOTING SUBGROUP-SPECIFIC DIFFERENTIATION TRAJECTORIES

NEURO-ONCOLOGY

IF13.4

2024-06-18

OAAI

Carmona, Enrique Blanco; Paassen, Irene; He, Jiayou; Buellesbach, Annette; Buhl, Juliane L.; Federico, Aniello; Liu, Ilon; Young, Matthew; Kildisiute, Gerda; Behjati, Sam; Vibhakar, Rajeev; Donson, Andrew; Foreman, Nicholas; Hovestadt, Volker; Shaw, McKenzie; Chi, Susan N.; Fruehwald, Michael; Korshunov, Andrey; Hasselblatt, Martin; Hoving, Eelco W.; Jaeger, Natalie; Johann, Pascal D.; Pfister, Stefan M.; Filbin, Mariella; Drost, Jarno; Kool, Marcel

A pathway-informed framework to infer synthetic lethal relationships in pediatric cancer

MOLECULAR CANCER THERAPEUTICS

IF5.5

2024-06-10

PREAI

Spinou, Anastasia; Gremmen, Richard; Veen, Puck; Drost, Jarno; Kemmeren, Patrick

The Virtual Child 虚拟的孩子

CANCER DISCOVERY

IF33.3

2024-04-04

OAAI

Gilbertson, Richard J.; Behjati, Sam; Boettcher, Anna-Lisa; Bronner, Marianne E.; Burridge, Matthew; Clausing, Henrick; Clifford, Harry; Danaher, Tracey; Donovan, Laura K.; Drost, Jarno; Eggermont, Alexander M. M.; Emerson, Chris; Flores, Mona G.; Hamerlik, Petra; Jabado, Nada; Jones, Andrew; Kaessmann, Henrick; Kleinman, Claudia L.; Kool, Marcel; Kutscher, Lena M.; Lindberg, Gavin; Linnane, Emily; Marioni, John C.; Maris, John M.; Monje, Michelle; Macaskill, Alexandra; Niederer, Steven; Northcott, Paul A.; Peeters, Elizabeth; Plieger-van Solkema, Willemijn; Preussner, Liane; Rios, Anne C.; Rippe, Karsten; Sandford, Peter; Sgourakis, Nikolaos G.; Shlien, Adam; Smith, Pete; Straathof, Karin; Sullivan, Patrick J.; Suva, Mario L.; Taylor, Michael D.; Thompson, Emma; Vento-Tormo, Roser; Wainwright, Brandon J.; Wechsler-Reya, Robert J.; Westermann, Frank; Winslade, Shannon; Al-Lazikani, Bissan; Pfister, Stefan M.

Advancing radiotherapy strategies for high-risk rhabdomyosarcoma: Unveiling BCLxL inhibition as a potent sensitizer to radiotherapy

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Park, Sammy Se Whee; Struyf, Nona; Erkers, Tom; Lehmann, Soren; Meister, Michael T.; Drost, Jarno; Holstege, Frank C.; Herold, Nikolas; Ostling, Paivi; Stenman, Jakob; Kallioniemi, Olli; Henter, Jan-Inge; Seashore-Ludlow, Brinton; Karlsson, Kasper

Tissue Organoid Cultures Metabolize Dietary Carcinogens Proficiently and Are Effective Models for DNA Adduct Formation

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2024-01-17

OAAI

Garcia, Angela L. Caipa; Kucab, Jill E.; Al-Serori, Halh; Beck, Rebekah S. S.; Bellamri, Madjda; Turesky, Robert J.; Groopman, John D.; Francies, Hayley E.; Garnett, Mathew J.; Huch, Meritxell; Drost, Jarno; Zilbauer, Matthias; Arlt, Volker M.; Phillips, David H.

研究方向