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Frank Kirchhoff

Ulm University

81H指数
487论文数
2.6W被引数
收录论文 219
发表时间
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Replication-competent SIVcpz CRISPR screen identifies barriers to successful cross-species transmission具有复制能力的SIVcpz CRISPR筛选识别成功种间传播的障碍
errJournal of Virology
IF3.8
err2026-06-23
err0
PREAI
errXie, Qinya; Wang, Qingxing; Noettger, Sabrina; Gosalbez, Guillermo; Betzler, Annika C.; Volcic, Meta; Kmiec, Dorota; Krebs, Stefan; Graf, Alexander; Gulensoy, Dila; Weidinger, Gilbert; Sparrer, Konstantin M. J.; Kirchhoff, Frank
err分享
err收藏
Human Coronavirus 229E Uses ORF4/4a to Antagonize the Host Restriction Factor SERINC5人冠状病毒229E利用ORF4/4a拮抗宿主限制因子SERINC5
errMedComm
IF10.7
err2026-05-29
err0
errOAAI
errQinya Xie; Sabrina Noettger; Jan Lawrenz; Sophie Stopper; Susanne Klute; Jan Münch; Dorota Kmiec; Qingxing Wang; Konstantin M. J. Sparrer; Frank Kirchhoff
err分享
err收藏
Nef stabilizes actin to prevent HIV-1 sensing by RIG-I-like receptorsNef稳定肌动蛋白以防止RIG-I样受体对HIV-1的感知
errNature Communications
IF15.7
err2025-12-07
err0
errOAAI
errAlexandre Laliberté; Caterina Prelli Bozzo; Dhiraj Acharya; Aurora De Luna; Maximilian Hirschenberger; Junji Zhu; Meta Volcic; Bettina Stolp; Cristina M. Rodriguez-Quinteros; Oliver T. Fackler; Michaela U. Gack; Konstantin M. J. Sparrer; Frank Kirchhoff
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err收藏
HIV-2 glycoproteins upregulate microRNAs 25 and 93 to counter the MARCH1 antiviral effect in macrophagesHIV-2糖蛋白上调microRNAs 25和93，以对抗巨噬细胞中的MARCH1抗病毒效应。
errJOURNAL OF VIROLOGY
IF3.8
err2025-11-01
err0
PREAI
errLodge, Robert; Kmiec, Dorota; Kirchhoff, Frank; Cohen, Eric A.
err分享
err收藏
Retinol Binding Protein 4 reactivates latent HIV-1 by triggering canonical NF-κB, JAK/STAT5 and JNK signalling视黄醇结合蛋白4通过触发经典NF-κB、JAK/STAT5和JNK信号通路来重新激活潜伏的HIV-1。
errSignal Transduction and Targeted Therapy
IF52.7
err2025-10-03
err0
errOAAI
errChiara Pastorio; Khumoekae Richard; Shariq Usmani; Ann-Kathrin Kissmann; Grigory Bolotnikov; Guillermo Gosálbez; Manuel Hayn; Lennart Koepke; Alina Sauertnik; Andrea Preising; Nico Preising; Ludger Ständker; Matthew Fair; Jessicamarie Morris; Emmanouil Papasavvas; Qin Liu; Honghong Sun; Armando Rodríguez; Karam Mounzer; Sebastian Wiese; Pablo Tebas; Yangzhu Du; Gregory M. Laird; Markus Jaritz; Frank Rosenau; Moritz M. Gaidt; Konstantin M. J. Sparrer; Luis J. Montaner; Frank Kirchhoff
err分享
err收藏
HIV-2 evades restriction by ZAP through adaptations in the U3 LTR region despite increased CpG levelsHIV-2通过U3 LTR区域的适应性改变逃避ZAP的限制，尽管CpG水平升高。
errNucleic Acids Research
IF13.1
err2025-08-30
err0
errOAAI
errDorota Kmiec; Rayhane Nchioua; Alexander Gabel; Asimenia Vlachou; Sabina Ganskih; Sümeyye Erdemci-Evin; Stacey A. Lapp; Diane G. Carnathan; Steven E. Bosinger; Ben Berkhout; Atze T. Das; Mathias Munschauer; Frank Kirchhoff
err分享
err收藏
GPR15LG binds CXCR4 and synergistically modulates CXCL12-induced cell signaling and migrationGPR15LG与CXCR4结合，并协同调节CXCL12诱导的细胞信号传导和迁移。
errCELL COMMUNICATION AND SIGNALING
IF8.9
err2025-05-20
err0
errOAAI
errAlbers, Dan Pascal Jean; Novikova, Sofya; Vieyto-Nunez, Julio; Almeida-Hernandez, Yasser; Pastorio, Chiara; Klassen, Florian; Weiss, Dana; von Maltitz, Pascal; Jaikishan, Janeni; Datta, Moumita; Jumaa, Hassan; Jebaraj, Billy Michael Chelliah; Stilgenbauer, Stephan; Kumar, Manish; Maity, Palash Chandra; Buske, Christian; Stifel, Ulrich; Zinngrebe, Julia; Fischer-Posovszky, Pamela; Chevigne, Andy; Kirchhoff, Frank; Sanchez-Garcia, Elsa; Muench, Jan; Harms, Mirja
err分享
err收藏
Trypstatin as a Novel TMPRSS2 Inhibitor with Broad-Spectrum Efficacy against Corona and Influenza VirusesTrypstatin作为一种新型TMPRSS2抑制剂，对冠状病毒和流感病毒具有广谱效力。
errADVANCED SCIENCE
IF14.1
err2025-05-14
err0
errOAAI
errLawrenz, J; Wettstein, L; Alfonso, AR; Nchioua, R; von Maltitz, P; Albers, DPJ; Zech, F; Vandeput, J; Naesens, L; Fois, G; Neubauer, V; Preising, N; Schmierer, E; Almeida-Hernandez, Y; Petersen, M; Staendker, L; Wiese, S; Braubach, P; Frick, M; Barth, E; Sauter, D; Kirchhoff, F; Sanchez-Garcia, E; Stevaert, A; Muench, J
err分享
err收藏
ReaxFF-Guided Optimization of VIRIP-Based HIV-1 Entry InhibitorsReaxFF引导的基于VIRIP的HIV-1进入抑制剂的优化
errJOURNAL OF PHYSICAL CHEMISTRY B
IF2.9
err2025-04-03
err0
errOAAI
errZech, Fabian; Jung, Christoph; Alfonso, Armando Alexei Rodriguez; Koehler, Janet; Staendker, Ludger; Weidinger, Gilbert; Jacob, Timo; Kirchhoff, Frank
err分享
err收藏
Host ZAP activity correlates with the levels of CpG suppression in primate lentiviruses宿主ZAP活性与灵长类慢病毒中CpG抑制水平相关。
errProceedings of the National Academy of Sciences
IF9.1
err2025-04-03
err0
errOAAI
errRayhane Nchioua; Dorota Kmiec; Veronika Krchlikova; Sarah Mattes; Sabrina Noettger; Frederic Bibollet-Ruche; Ronnie M. Russell; Konstantin M. J. Sparrer; Thomas Charpentier; Frédéric Tardy; Steven E. Bosinger; Daniel Sauter; Beatrice H. Hahn; Frank Kirchhoff
err分享
err收藏
Role of N-linked glycosylation sites in human ACE2 in SARS-CoV-2 and hCoV-NL63 infection
errJOURNAL OF VIROLOGY
IF3.8
err2025-03-01
err0
errOAAI
errNoettger, Sabrina; Zech, Fabian; Nchioua, Rayhane; Pastorio, Chiara; Jung, Christoph; Jacob, Timo; Stenger, Steffen; Kirchhoff, Frank
err分享
err收藏
α-Synuclein fibrils enhance HIV-1 infection of human T cells, macrophages and microgliaα-突触核蛋白纤维增强HIV-1对人类T细胞、巨噬细胞和小胶质细胞的感染
errNATURE COMMUNICATIONS
IF15.7
err2025-01-18
err1
errOAAI
errOlari, Lia-Raluca; Liu, Sichen; Arnold, Franziska; Kuehlwein, Julia; Miro, Marta Gil; Updahaya, Ajeet Rijal; Stuerzel, Christina; Thal, Dietmar Rudolf; Walther, Paul; Sparrer, Konstantin M. J.; Danzer, Karin M.; Muench, Jan; Kirchhoff, Frank
err分享
err收藏
Acquisition of a multibasic cleavage site does not increase MERS-CoV entry into Calu-3 human lung cells获得多碱基切割位点不会增加mers-cov进入Calu-3人肺细胞
errJOURNAL OF VIROLOGY
IF3.8
err2024-11-19
err0
PREAI
errHoffmann, Markus; Kleine-Weber, Hannah; Graichen, Luise; Nehlmeier, Inga; Kempf, Amy; Moldenhauer, Anna-Sophie; Braun, Elisabeth; Assiri, Abdullah M.; Kirchhoff, Frank; Sauter, Daniel; Alkharsah, Khaled R.; Poehlmann, Stefan
err分享
err收藏
Antiviral mechanisms of guanylate-binding protein 5: versatile inhibition of multiple viral glycoproteins鸟苷酸结合蛋白5的抗病毒机制: 多种病毒糖蛋白的多功能抑制
errMBIO
IF4.7
err2024-11-13
err0
errOAAI
errSauter, Daniel; Kirchhoff, Frank
err分享
err收藏
CD4 downregulation precedes Env expression and protects HIV-1-infected cells from ADCC mediated by non-neutralizing antibodies
errMBIO
IF4.7
err2024-11-13
err0
errOAAI
errRichard, Jonathan; Sannier, Geremy; Zhu, Li; Prevost, Jeremie; Marchitto, Lorie; Benlarbi, Mehdi; Beaudoin-Bussieres, Guillaume; Kim, Hongil; Sun, Yaping; Chatterjee, Debashree; Medjahed, Halima; Bourassa, Catherine; Delgado, Gloria-Gabrielle; Dube, Mathieu; Kirchhoff, Frank; Hahn, Beatrice H.; Kumar, Priti; Kaufmann, Daniel E.; Finzi, Andres
err分享
err收藏
A naturally occurring 22-amino acid fragment of human hemoglobin A inhibits autophagy and HIV-1
errCELLULAR AND MOLECULAR LIFE SCIENCES
IF6.2
err2024-09-17
err0
errOAAI
errFreisem, Dennis; Rodriguez-Alfonso, Armando A.; Lawrenz, Jan; Zhou, Zhixuan; Monecke, Thomas; Preising, Nico; Endres, Sascha; Wiese, Sebastian; Staendker, Ludger; Kuan, Seah-Ling; Thal, Dietmar R.; Weil, Tanja; Niessing, Dierk; Barth, Holger; Kirchhoff, Frank; Harms, Mirja; Muench, Jan; Sparrer, Konstantin M. J.
err分享
err收藏
A Gaussia luciferase reporter assay for the evaluation of coronavirus Nsp5/3CLpro activity
errSCIENTIFIC REPORTS
IF3.9
err2024-09-05
err1
errOAAI
errVlachou, Asimenia; Nchioua, Rayhane; Regensburger, Kerstin; Kirchhoff, Frank; Kmiec, Dorota
err分享
err收藏
Attenuated replication and damaging effects of SARS-CoV-2 Omicron variants in an intestinal epithelial barrier model肠上皮屏障模型中SARS-CoV-2 Omicron变体的减弱复制和破坏作用
errJOURNAL OF MEDICAL VIROLOGY
IF4.6
err2024-07-05
err1
errOAAI
errVolcic, Meta; Nchioua, Rayhane; Pastorio, Chiara; Zech, Fabian; Haussmann, Isabell; Sauter, Daniel; Read, Clarissa; Walther, Paul; Kirchhoff, Frank
err分享
err收藏
RPLP1 restricts HIV-1 transcription by disrupting C/EBPβ binding to the LTR
errNATURE COMMUNICATIONS
IF15.7
err2024-06-21
err1
errOAAI
errYang, Weijing; Wang, Hong; Li, Zhaolong; Zhang, Lihua; Liu, Jianhui; Kirchhoff, Frank; Huan, Chen; Zhang, Wenyan
err分享
err收藏
Replication competent HIV-guided CRISPR screen identifies antiviral factors including targets of the accessory protein Nef
errNATURE COMMUNICATIONS
IF15.7
err2024-05-07
err2
errOAAI
errPrelli Bozzo, Caterina; Laliberte, Alexandre; De Luna, Aurora; Pastorio, Chiara; Regensburger, Kerstin; Krebs, Stefan; Graf, Alexander; Blum, Helmut; Volcic, Meta; Sparrer, Konstantin; Kirchhoff, Frank
err分享
err收藏

研究方向

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合作学者
合作期刊
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Michel C. Nussenzweig
H 指数: 183 · 论文数: 618
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H 指数: 161 · 论文数: 1.1K
A
Arturo Casadevall
H 指数: 144 · 论文数: 1.5K
M
Michael E. Greenberg
H 指数: 141 · 论文数: 325
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