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D

Donita C. Brady

University of Pennsylvania
H指数:29
被引数:5,691

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Copper depletion boosts CNS leukemia therapy by inhibiting nucleotide synthesis through impairment of mitochondrial complex IV activity

铜耗竭通过线粒体复合物IV活性受损抑制核苷酸合成来促进中枢神经系统白血病治疗

Nature Cancer
IF28.5
2026-05-250
PRE
Alan Y. L. Wong; Jacob W. Myers; Gyan Prakash; Alice Ma; Jeannette R. Brook; Boryana Petrova; Baran Bulut; Ralph White; Catherine Merz; Maeve de Souza; Adam G. Maynard; Peng Wang; Amy Yu; Nancy K. Pohl; Michal Weitman; Lewis B. Silverman; Kimberly Stegmaier; L. Stirling Churchman; Peter D. Cole; Donita C. Brady; Naama Kanarek
Oxidation state-specific fluorescent copper sensors reveal oncogene-driven redox changes that regulate labile copper(II) pools

氧化态特异性荧光铜传感器揭示了癌基因驱动的氧化还原变化，调节不稳定的铜 (II) 池

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2022-10-1730
OAAI
Pezacki, Aidan T.; Matier, Carson D.; Gu, Xingxing; Kummelstedt, Eric; Bond, Sarah E.; Torrente, Laura; Jordan-Sciutto, Kelly L.; DeNicola, Gina M.; Su, Timothy A.; Brady, Donita C.; Chang, Christopher J.
Connecting copper and cancer: from transition metal signalling to metalloplasia

连接铜和癌症: 从过渡金属信号到金属增生

NATURE REVIEWS CANCER
IF66.8
2021-11-11734
OA
Ge, Eva J.; Bush, Ashley I.; Casini, Angela; Cobine, Paul A.; Cross, Justin R.; DeNicola, Gina M.; Dou, Q. Ping; Franz, Katherine J.; Gohil, Vishal M.; Gupta, Sanjeev; Kaler, Stephen G.; Lutsenko, Svetlana; Mittal, Vivek; Petris, Michael J.; Polishchuk, Roman; Ralle, Martina; Schilsky, Michael L.; Tonks, Nicholas K.; Vahdat, Linda T.; Van Aelst, Linda; Xi, Dan; Yuan, Peng; Brady, Donita C.; Chang, Christopher J.

研究方向

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J
Jessica M. Posimo
H 指数:17论文数:63被引数:1,171
C
Christopher M. Counter
H 指数:57论文数:207被引数:2.0万
T
Tiffany Tsang
H 指数:25论文数:112被引数:2,878
A
Adrienne D. Cox
H 指数:73论文数:517被引数:1.9万
C
Christopher J. Chang
H 指数:121论文数:569被引数:5.6万
D
David F. Kashatus
H 指数:29论文数:74被引数:4,047
D
Dennis J. Thiele
H 指数:90论文数:239被引数:2.7万
M
Michelle L. Turski
H 指数:15论文数:52被引数:2,150
P
Paul A. Cobine
H 指数:40论文数:134被引数:7,105
G
Gina M. DeNicola
H 指数:41论文数:314被引数:1.5万