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Steering research on mRNA splicing in cancer towards clinical translation 癌症中mRNA剪接的研究转向临床翻译 Anczukow, Olga; Allain, Frederic H. -T.; Angarola, Brittany L.; Black, Douglas L.; Brooks, Angela N.; Cheng, Chonghui; Conesa, Ana; Crosse, Edie I.; Eyras, Eduardo; Guccione, Ernesto; Lu, Sydney X.; Neugebauer, Karla M.; Sehgal, Priyanka; Song, Xiao; Tothova, Zuzana; Valcarcel, Juan; Weeks, Kevin M.; Yeo, Gene W.; Thomas-Tikhonenko, Andrei 分享 收藏
SRSF6 modulates histone-chaperone HIRA splicing to orchestrate AR and E2F activity in prostate cancer Montero-Hidalgo, Antonio J.; Jimenez-Vacas, Juan M.; Gomez-Gomez, Enrique; Porcel-Pastrana, Francisco; Saez-Martinez, Prudencio; Perez-Gomez, Jesus M.; Fuentes-Fayos, Antonio C.; Blazquez-Encinas, Ricardo; Sanchez-Sanchez, Rafael; Gonzalez-Serrano, Teresa; Castro, Elena; Lopez-Soto, Pablo J.; Carrasco-Valiente, Julia; Sarmento-Cabral, Andre; Martinez-Fuentes, Antonio J.; Eyras, Eduardo; Castano, Justo P.; Sharp, Adam; Olmos, David; Gahete, Manuel D.; Luque, Raul M. 分享 收藏
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Prediction of m6A and m5C at single-molecule resolution reveals a transcriptome-wide co-occurrence of RNA modifications 在单分子分辨率下预测m6A和m5C揭示了RNA修饰的转录组范围内的共同发生 Mateos, P. Acera; Sethi, A.; Ravindran, A.; Srivastava, A.; Woodward, K.; Mahmud, S.; Kanchi, M.; Guarnacci, M.; Xu, J.; Yuen, Z.; Zhou, Y.; Sneddon, A.; Hamilton, W.; Gao, J.; Starrs, L.; Hayashi, R.; Wickramasinghe, V; Zarnack, K.; Preiss, T.; Burgio, G.; Dehorter, N.; Shirokikh, N.; Eyras, E. 分享 收藏
Comprehensive translational profiling and STE AI uncover rapid control of protein biosynthesis during cell stress 全面的翻译分析和STE AI揭示了细胞应激过程中蛋白质生物合成的快速控制 Horvath, Attila; Janapala, Yoshika; Woodward, Katrina; Mahmud, Shafi; Cleynen, Alice; Gardiner, Elizabeth E.; Hannan, Ross D.; Eyras, Eduardo; Preiss, Thomas; Shirokikh, Nikolay E. 分享 收藏
Integrative single-cell expression and functional studies unravels a sensitization to cytarabine-based chemotherapy through HIF pathway inhibition in AML leukemia stem cells Velasco-Hernandez, Talia; Trincado, Juan L.; Vinyoles, Meritxell; Closa, Adria; Martinez-Moreno, Alba; Gutierrez-Aguera, Francisco; Molina, Oscar; Rodriguez-Cortez, Virginia C.; Ximeno-Parpal, Pau; Fernandez-Fuentes, Narcis; Petazzi, Paolo; Beneyto-Calabuig, Sergi; Velten, Lars; Romecin, Paola; Casquero, Raquel; Abollo-Jimenez, Fernando; de la Guardia, Rafael D.; Lorden, Patricia; Bataller, Alex; Lapillonne, Helene; Stam, Ronald W.; Vives, Susana; Torrebadell, Montserrat; Fuster, Jose L.; Bueno, Clara; Sarry, Jean-Emmanuel; Eyras, Eduardo; Heyn, Holger; Menendez, Pablo 分享 收藏
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Formation of an invasion-permissive matrix requires TGFβ/SNAIL1-regulated alternative splicing of fibronectin Franco-Valls, Hector; Tusquets-Uxo, Elsa; Sala, Laura; Val, Maria; Pena, Raul; Iaconcig, Alessandra; Villarino, Alvaro; Jimenez-Arriola, Martin; Masso, Pere; Trincado, Juan L.; Eyras, Eduardo; Muro, Andres F.; Otero, Jorge; de Herreros, Antonio Garcia; Baulida, Josep 分享 收藏
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Tumor suppressor role of RBM22 in prostate cancer acting as a dual-factor regulating alternative splicing and transcription of key oncogenic genes Jimenez-Vacas, Juan M.; Montero-Hidalgo, Antonio J.; Gomez-Gomez, Enrique; Saez-Martinez, Prudencio; Fuentes-Fayos, Antonio C.; Closa, Adria; Gonzalez-Serrano, Teresa; Martinez-Lopez, Ana; Sanchez-Sanchez, Rafael; Lopez-Casas, Pedro P.; Sarmento-Cabral, Andre; Olmos, David; Eyras, Eduardo; Castano, Justo P.; Gahete, Manuel D.; Luque, Raul M. 分享 收藏
Psi promotes Drosophila wing growth via direct transcriptional activation of cell and of inhibitors Psi通过细胞和抑制剂的直接转录激活促进果蝇翅膀的生长 Zaytseva, Olga; Mitchell, Naomi C.; Muckle, Damien; Delandre, Caroline; Nie, Zuqin; Werner, Janis K.; Lis, John T.; Eyras, Eduardo; Hannan, Ross D.; Levens, David L.; Marshall, Owen J.; Quinn, Leonie M. 分享 收藏
A convergent malignant phenotype in B-cell acute lymphoblastic leukemia involving the splicing factor SRRM1 Closa, Adria; Reixachs-Sole, Marina; Fuentes-Fayos, Antonio C.; Hayer, Katharina E.; Melero, Juan L.; Adriaanse, Fabienne R. S.; Bos, Romy S.; Torres-Diz, Manuel; Hunger, Stephen P.; Roberts, Kathryn G.; Mullighan, Charles G.; Stam, Ronald W.; Thomas-Tikhonenko, Andrei; Castano, Justo P.; Luque, Raul M.; Eyras, Eduardo 分享 收藏
Cannabinoid signaling modulation through JZL184 restores key phenotypes of a mouse model for Williams-Beuren syndrome Navarro-Romero, Alba; Galera-Lopez, Lorena; Ortiz-Romero, Paula; Llorente-Ovejero, Alberto; De los Reyes-Ramirez, Lucia; Bengoetxea de Tena, Iker; Garcia-Elias, Anna; Mas-Stachurska, Aleksandra; Reixachs-Sole, Marina; Pastor, Antoni; de la Torre, Rafael; Maldonado, Rafael; Benito, Begona; Eyras, Eduardo; Rodriguez-Puertas, Rafael; Campuzano, Victoria; Ozaita, Andres 分享 收藏
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Altered regulation of BRCA1 exon 11 splicing is associated with breast cancer risk in carriers of BRCA1 pathogenic variants BRCA1外显子11剪接调控的改变与BRCA1致病变异携带者的乳腺癌风险相关 Ruiz de Garibay, Gorka; Fernandez-Garcia, Ignacio; Mazoyer, Sylvie; de Calais, Flavia Leme; Ameri, Pietro; Vijayakumar, Sangeetha; Martinez-Ruiz, Haydeliz; Damiola, Francesca; Barjhoux, Laure; Thomassen, Mads; Andersen, Lars v B.; Herranz, Carmen; Mateo, Francesca; Palomero, Luis; Espin, Roderic; Gomez, Antonio; Garcia, Nadia; Jimenez, Daniel; Bonifaci, Nuria; Extremera, Ana, I; Castano, Julio; Raya, Angel; Eyras, Eduardo; Puente, Xose S.; Brunet, Joan; Lazaro, Conxi; Radice, Paolo; Barnes, Daniel R.; Antoniou, Antonis C.; Spurdle, Amanda B.; de la Hoya, Miguel; Baralle, Diana; Barcellos-Hoff, Mary Helen; Pujana, Miquel A. 分享 收藏
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