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N

Nicholas D. Huntington

Monash University
H指数:65
被引数:1.6万

个人简介

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教育背景

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工作经历

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荣誉奖项

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Core fucosylation of IL-2RB is required for natural killer cell homeostasis

IL-2RB的核心岩藻糖基化对于自然杀伤细胞稳态是必需的。

Cell Reports
IF6.9
2025-08-020
OA
Harrison Sudholz; Xiangpeng Meng; Hae-Young Park; Zihan Shen; Iva Nikolic; Joseph Cursons; Ethan D. Goddard-Borger; Iona S. Schuster; Christopher E. Andoniou; Mariapia A. Degli-Esposti; Nichollas E. Scott; Michael Chopin; Jai Rautela; Sebastian Scheer; Nicholas D. Huntington
Lymph-node-derived stem-like but not tumor-tissue-resident CD8+ T cells fuel anticancer immunity

淋巴结来源的干细胞样但不是肿瘤组织驻留的CD8 T细胞燃料抗癌免疫

Nature Immunology
IF27.6
2025-07-290
PRE
Sharanya K. M. Wijesinghe; Lisa Rausch; Sarah S. Gabriel; Giovanni Galletti; Marco De Luca; Lei Qin; Lifen Wen; Carlson Tsui; Kevin Man; Leonie Heyden; Teisha Mason; Lewis D. Newland; Andrew Kueh; Yang Liao; David Chisanga; Julian Swatler; Emanuele Voulaz; Giuseppe Marulli; Valentina Errico; Agnese Losurdo; Gustavo R. Rossi; Fernando Souza-Fonseca-Guimaraes; Nicholas D. Huntington; Thomas Gebhardt; Daniel T. Utzschneider; Marco J. Herold; Wei Shi; Jan Schroeder; Enrico Lugli; Axel Kallies
Enhancing anti-tumor immunity of natural killer cells through targeting IL-15R signaling

通过靶向IL-15R信号增强NK细胞的抗肿瘤免疫

Cancer Cell
IF44.5
2025-06-120
PRE
Iva Nikolic; Joseph Cursons; Benjamin Shields; Stephane Chappaz; Harrison Sudholz; Xiangpeng Meng; Patrick Constantinescu; Reshma Vijayakumaran; Michael D’Angelo; Momeneh Foroutan; David Ladd; Matthew Veldman; Jason Glab; Tahlia Procter; Hae-Young Park; Julian Contet; Felix Deuss; Kahlia Wong; Yi Sun; Richard Berry; Jai Rautela; Nicholas D. Huntington
Context-restricted PD-(L)1 checkpoint agonism by CTLA4-Ig therapies inhibits T cell activity
CELL REPORTS
IF6.9
2024-10-010
OAAI
Oxley, Ethan P.; Kershaw, Nadia J.; Louis, Cynthia; Goodall, Katharine J.; Garwood, Maximilian M.; Ho, Skye Min Jee; Voo, Veronica T. F.; Park, Hae-Young; Iaria, Josephine; Wong, Lilian L. L.; Lebenbaum, Ariel G.; Wiranata, Stephanie; Pang, Ee Shan; Edwards, Emily S. J.; D'Silva, Damian B.; Hansen, Jacinta; van Zelm, Menno C.; O'Keeffe, Meredith; Hogarth, P. Mark; Haynes, Nicole M.; Huntington, Nicholas D.; Wicks, Ian P.; Dickins, Ross A.
Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cell (vol 18, pg 1004, 2017)

通过将效应NK细胞转化为1型先天淋巴样细胞来逃避肿瘤免疫 (第18卷，1004页，2017页)

NATURE IMMUNOLOGY
IF27.6
2024-03-210
OA
Gao, Yulong; Souza-Fonseca-Guimaraes, Fernando; Bald, Tobias; Ng, Susanna S.; Young, Arabella; Ngiow, Shin Foong; Rautela, Jai; Straube, Jasmin; Waddell, Nic; Blake, Stephen J.; Yan, Juming; Bartholin, Laurent; Lee, Jason S.; Vivier, Eric; Takeda, Kazuyoshi; Messaoudene, Meriem; Zitvogel, Laurence; Teng, Michele W. L.; Belz, Gabrielle T.; Engwerda, Christian R.; Huntington, Nicholas D.; Nakamura, Kyohei; Hoelzel, Michael; Smyth, Mark J.
Interferon-epsilon is a novel regulator of NK cell responses in the uterus
EMBO MOLECULAR MEDICINE
IF8.3
2024-01-231
OAAI
Mayall, Jemma R.; Horvat, Jay C.; Mangan, Niamh E.; Chevalier, Anne; McCarthy, Huw; Hampsey, Daniel; Donovan, Chantal; Brown, Alexandra C.; Matthews, Antony Y.; de Weerd, Nicole A.; de Geus, Eveline D.; Starkey, Malcolm R.; Kim, Richard Y.; Daly, Katie; Goggins, Bridie J.; Keely, Simon; Maltby, Steven; Baldwin, Rennay; Foster, Paul S.; Boyle, Michael J.; Tanwar, Pradeep S.; Huntington, Nicholas D.; Hertzog, Paul J.; Hansbro, Philip M.
IKAROS and AIOLOS directly regulate AP-1 transcriptional complexes and are essential for NK cell development
NATURE IMMUNOLOGY
IF27.6
2024-01-056
OA
Goh, Wilford; Sudholz, Harrison; Foroutan, Momeneh; Scheer, Sebastian; Pfefferle, Aline; Delconte, Rebecca B.; Meng, Xiangpeng; Shen, Zihan; Hennessey, Robert; Kong, Isabella Y.; Schuster, Iona S.; Andoniou, Christopher E.; Davis, Melissa J.; Hediyeh-Zadeh, Soroor; Souza-Fonseca-Guimaraes, Fernando; Parish, Ian A.; Beavis, Paul; Thiele, Daniel; Chopin, Michael; Degli-Esposti, Mariapia A.; Cursons, Joe; Kallies, Axel; Rautela, Jai; Nutt, Stephen L.; Huntington, Nicholas D.
CIS is a potent checkpoint in NK cell-mediated tumor immunity (vol 17, pg 816, 2016)
NATURE IMMUNOLOGY
IF27.6
2023-12-120
OA
Delconte, Rebecca B.; Kolesnik, Tatiana B.; Dagley, Laura F.; Rautela, Jai; Shi, Wei; Putz, Eva M.; Stannard, Kimberley; Zhang, Jian-Guo; Teh, Charis; Firth, Matt; Ushiki, Takashi; Andoniou, Christopher E.; Degli-Esposti, Mariapia A.; Sharp, Phillip P.; Sanvitale, Caroline E.; Infusini, Giuseppe; Liau, Nicholas P. D.; Linossi, Edmond M.; Burns, Christopher J.; Carotta, Sebastian; Gray, Daniel H. D.; Seillet, Cyril; Hutchinson, Dana S.; Belz, Gabrielle T.; Webb, Andrew I.; Alexander, Warren S.; Li, Shawn S.; Bullock, Alex N.; Babon, Jeffrey J.; Smyth, Mark J.; Nicholson, Sandra E.; Huntington, Nicholas D.
Therapeutic inhibition of the SRC-kinase HCK facilitates T cell tumor infiltration and improves response to immunotherapy
SCIENCE ADVANCES
IF12.5
2022-06-2418
OAAI
Poh, Ashleigh R.; Love, Christopher G.; Chisanga, David; Steer, James H.; Baloyan, David; Chopin, Michael; Nutt, Stephen; Rautela, Jai; Huntington, Nicholas D.; Etemadi, Nima; O'Brien, Megan; O'Keefe, Ryan; Ellies, Lesley G.; Macri, Christophe; Mintern, Justine D.; Whitehead, Lachlan; Gangadhara, Gangadhara; Boon, Louis; Chand, Ashwini L.; Lowell, Clifford A.; Shi, Wei; Pixley, Fiona J.; Ernst, Matthias

研究方向

暂未获取到该数据
J
Jai Rautela
H 指数:28论文数:110被引数:4,965
F
Fernando Souza-Fonseca-Guimarães
H 指数:40论文数:171被引数:6,654
G
Gabrielle T. Belz
H 指数:92论文数:410被引数:2.7万
M
Mark J. Smyth
H 指数:172论文数:1,383被引数:11.8万
R
Rebecca B. Delconte
H 指数:17论文数:33被引数:1,850
S
Stephen L. Nutt
H 指数:100论文数:408被引数:3.2万
É
Éric Vivier
H 指数:124论文数:694被引数:6.1万
M
Mariapia A. Degli‐Esposti
H 指数:56论文数:202被引数:1.2万
Wei Shi 封面图
Wei Shi
H 指数:55论文数:186被引数:9.7万
S
Sebastian Carotta
H 指数:38论文数:121被引数:8,950