logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
delete
arrow
返回
K

Kevin Litchfield

university college london

52H指数
374论文数
1.3W被引数
收录论文 89
发表时间
logo
A preinvasive regulatory T cell axis for lung cancer interception肺癌拦截的侵袭前调节性T细胞轴
errNature
IF48.5
err2026-10-07
err0
errOAAI
errSamuel Gamble; Zoe E. Whiteman; Claudia Peinador-Marín; Marta Lebrusant-Fernandez; Abigail Y. L. Shurr; Andrei Enica; Teerapon Sahwangarrom; Seng Kuong Anakin Ung; Amber Rogers; Petros Fessas; Chuen Ryan Khaw; Lukas Kalinke; Constantin Ahlmann-Eltze; Ahmed S. N. Alhendi; Kate Otter; Xiuchuan Hu; Krupa Thakkar; Betty Gration; Izzy Newsham; Imran Uddin; Ellen Nuttall Musson; Kyren A. Lazarus; Moritz J. Przybilla; Adam Pennycuick; Helen Hall; Zoe Hagel; Charlotte Percival; Ruth Prendecki; Sophie Tisi; Georgia Constantinou; Pascal F. Durrenberger; Kate H. C. Gowers; Yien Ning Sophia Wong; Mark Linch; Kevin Litchfield; Elspeth M. Payne; Se-Hoon Lee; Sergio A. Quezada; Peter J. Campbell; Jennifer E. Beane; Sarah A. Mazzilli; David A. Moore; Vitor H. Teixeira; Sandra Gómez-López; Bart Vanhaesebroeck; Sam M. Janes; James L. Reading
err分享
err收藏
Immunotherapy drug target identification using machine learning and patient-derived tumour explant validation使用机器学习和患者来源的肿瘤外植体验证进行免疫治疗药物靶标鉴定
errNature Machine Intelligence
IF23.9
err2026-05-18
err0
errOAAI
errMarcellus Augustine; Nuno Rocha Nene; Hongchang Fu; Christopher L. Pinder; Lorena Ligammari; Alexander P. Simpson; Irene Sanz-Fernández; Krupa Thakkar; Danwen Qian; Evelyn Fitzsimons; Benjamin S. Simpson; Roberto Vendramin; Andrea Castro; Heather Niederer; Samra Turajlic; Sergio A. Quezada; Nicholas McGranahan; Chris Watkins; Charles Swanton; Kevin Litchfield
err分享
err收藏
Retraction Note: Antibodies against endogenous retroviruses promote lung cancer immunotherapy撤稿注意: 针对内源性逆转录病毒的抗体促进肺癌免疫治疗
errNature
IF48.5
err2026-01-14
err0
errOAAI
errKevin W. Ng; Jesse Boumelha; Katey S. S. Enfield; Jorge Almagro; Hongui Cha; Oriol Pich; Takahiro Karasaki; David A. Moore; Roberto Salgado; Monica Sivakumar; George Young; Miriam Molina-Arcas; Sophie de Carné Trécesson; Panayiotis Anastasiou; Annika Fendler; Lewis Au; Scott T. C. Shepherd; Carlos Martínez-Ruiz; Clare Puttick; James R. M. Black; Thomas B. K. Watkins; Hyemin Kim; Seohee Shim; Nikhil Faulkner; Jan Attig; Selvaraju Veeriah; Neil Magno; Sophia Ward; Alexander M. Frankell; Maise Al Bakir; Emilia L. Lim; Mark S. Hill; Gareth A. Wilson; Daniel E. Cook; Nicolai J. Birkbak; Axel Behrens; Nadia Yousaf; Sanjay Popat; Allan Hackshaw; Crispin T. Hiley; Kevin Litchfield; Nicholas McGranahan; Mariam Jamal-Hanjani; James Larkin; Se-Hoon Lee; Samra Turajlic; Charles Swanton; Julian Downward; George Kassiotis
err分享
err收藏
Subclonal immune evasion in non-small cell lung cancer非小细胞肺癌中的亚克隆免疫逃逸
errCancer Cell
IF44.5
err2025-07-03
err0
errOAAI
errKrijn K. Dijkstra; Roberto Vendramin; Despoina Karagianni; Maartje Witsen; Felipe Gálvez-Cancino; Mark S. Hill; Kane A. Foster; Vittorio Barbè; Mihaela Angelova; Robert E. Hynds; David R. Pearce; Carlos Martínez-Ruiz; James R.M. Black; Ariana Huebner; Oriol Pich; Andrew Rowan; Marcellus Augustine; Clare Puttick; David A. Moore; Lydia L. Liu; Sadegh Saghafinia; Joris van de Haar; Selvaraju Veeriah; Cristina Naceur-Lombardelli; Antonia Toncheva; Supreet Kaur Bola; Crispin T. Hiley; Mariam Jamal-Hanjani; Nicholas McGranahan; Kevin Litchfield; James L. Reading; Benny Chain; Sergio A. Quezada; Emile E. Voest; Charles Swanton
err分享
err收藏
Regulatory T cell depletion promotes myeloid cell activation and glioblastoma response to anti-PD1 and tumor-targeting antibodies调节性T细胞耗竭促进髓系细胞活化及胶质母细胞瘤对anti-PD1和肿瘤靶向抗体的反应
errImmunity
IF26.3
err2025-05-29
err0
errOAAI
errFelipe Galvez-Cancino; Mariela Navarrete; Gordon Beattie; Simone Puccio; Enrique Conde-Gallastegi; Kane Foster; Yasmin Morris; Teerapon Sahwangarrom; Despoina Karagianni; Jiali Liu; Alvin J.X. Lee; Dimitrios A. Garyfallos; Alexander P. Simpson; Gerasimos-Theodoros Mastrokalos; Francesco Nannini; Cristobal Costoya; Varshaa Anantharam; Beatrice Claudia Cianciotti; Leanne Bradley; Claudia Garcia-Diaz; Melanie Clements; Aditya Shroff; Fatemeh Vahid Dastjerdi; Enrique Miranda Rota; Shahida Sheraz; Robert Bentham; Imran Uddin; Henning Walczak; Alvaro Lladser; James L. Reading; Kerry A. Chester; Martin A. Pule; Paul M. Brennan; Samuel Marguerat; Simona Parrinello; Karl S. Peggs; Nicholas McGranahan; Enrico Lugli; Kevin Litchfield; Steven M. Pollard; Sergio A. Quezada
err分享
err收藏
Meta-analysis of Germline Whole-exome Sequencing in 1435 Cases of Testicular Germ Cell Tumour to Evaluate Disruptive Mutations Under Dominant, Recessive, and X-linked Inheritance Models1435例睾丸生殖细胞肿瘤种系全外显子测序的Meta分析，以评估显性，隐性和X连锁遗传模型下的破坏性突变
errEUROPEAN UROLOGY OPEN SCIENCE
IF4.5
err2025-03-01
err0
errOAAI
errKuzbari, Zeid; Rowlands, Charlie F.; Wade, Isaac; Garrett, Alice; Loveday, Chey; Choi, Subin; Torr, Beth; Litchfield, Kevin; Reid, Alison; Huddart, Robert; Broderick, Peter; Houlston, Richard S.; Turnbull, Clare
err分享
err收藏
MHC Hammer reveals genetic and non-genetic HLA disruption in cancer evolutionMHC Hammer揭示了癌症进化中的遗传和非遗传HLA破坏
errNATURE GENETICS
IF31.8
err2024-10-02
err0
errOAAI
errPuttick, Clare; Jones, Thomas P.; Leung, Michelle M.; Galvez-Cancino, Felipe; Liu, Jiali; Varas-Godoy, Manuel; Rowan, Andrew; Pich, Oriol; Martinez-Ruiz, Carlos; Bentham, Robert; Dijkstra, Krijn K.; Black, James R. M.; Rosenthal, Rachel; Kanu, Nnennaya; Litchfield, Kevin; Salgado, Roberto; Moore, David A.; Van Loo, Peter; Jamal-Hanjani, Mariam; Quezada, Sergio A.; Swanton, Charles; Mcgranahan, Nicholas
err分享
err收藏
Genomic and immune heterogeneity of multiple synchronous lung adenocarcinoma at different developmental stages不同发育阶段的多发性同步肺腺癌的基因组和免疫异质性
errNATURE COMMUNICATIONS
IF15.7
err2024-09-10
err1
errOAAI
errZhao, Yue; Gao, Jian; Wang, Jun; Fan, Fanfan; Cheng, Chao; Qian, Danwen; Guo, Ran; Zhang, Yang; Ye, Ting; Augustine, Marcellus; Lin, Yicong; Shang, Jun; Li, Hang; Pan, Yunjian; Huang, Qingyuan; Chen, Haiqing; Han, Han; Gao, Zhendong; Wang, Qiming; Zhang, Shiyue; Zhang, Mou; Fu, Fangqiu; Yan, Yueren; Patel, Shanila Fernandez; Vendramin, Roberto; Yuan, Hui; Zhang, Yawei; Xiang, Jiaqing; Hu, Hong; Sun, Yihua; Li, Yuan; Litchfield, Kevin; Cao, Zhiwei; Chen, Haiquan
err分享
err收藏
Whole genome sequencing refines stratification and therapy of patients with clear cell renal cell carcinoma全基因组测序细化肾透明细胞癌患者的分层和治疗
errNATURE COMMUNICATIONS
IF15.7
err2024-07-15
err1
errOAAI
errCulliford, Richard; Lawrence, Samuel E. D.; Mills, Charlie; Tippu, Zayd; Chubb, Daniel; Cornish, Alex J.; Browning, Lisa; Kinnersley, Ben; Bentham, Robert; Sud, Amit; Pallikonda, Husayn; Frangou, Anna; Gruber, Andreas J.; Litchfield, Kevin; Wedge, David; Larkin, James; Turajlic, Samra; Houlston, Richard S.
err分享
err收藏
Using a pan-cancer atlas to investigate tumour associated macrophages as regulators of immunotherapy response使用泛癌症图谱研究肿瘤相关巨噬细胞作为免疫治疗反应的调节剂
errNATURE COMMUNICATIONS
IF15.7
err2024-07-06
err6
errOAAI
errCoulton, Alexander; Murai, Jun; Qian, Danwen; Thakkar, Krupa; Lewis, Claire E.; Litchfield, Kevin
err分享
err收藏
Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancer均聚物开关介导错配修复缺陷型结直肠癌的适应性可变性
errNATURE GENETICS
IF31.8
err2024-07-03
err1
errOAAI
errKayhanian, Hamzeh; Cross, William; van der Horst, Suzanne E. M.; Barmpoutis, Panagiotis; Lakatos, Eszter; Caravagna, Giulio; Zapata, Luis; Van Hoeck, Arne; Middelkamp, Sjors; Litchfield, Kevin; Steele, Christopher; Waddingham, William; Patel, Dominic; Milite, Salvatore; Jin, Chen; Baker, Ann-Marie; Alexander, Daniel C.; Khan, Khurum; Hochhauser, Daniel; Novelli, Marco; Werner, Benjamin; van Boxtel, Ruben; Hageman, Joris H.; Buissant des Amorie, Julian R.; Linares, Josep; Ligtenberg, Marjolijn J. L.; Nagtegaal, Iris D.; Lacle, Miangela M.; Moons, Leon M. G.; Brosens, Lodewijk A. A.; Pillay, Nischalan; Sottoriva, Andrea; Graham, Trevor A.; Rodriguez-Justo, Manuel; Shiu, Kai-Keen; Snippert, Hugo J. G.; Jansen, Marnix
err分享
err收藏
Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models基因组内异质性在多区域非小细胞肺癌患者来源的异种移植模型中的表现
errNATURE COMMUNICATIONS
IF15.7
err2024-05-31
err4
errOAAI
errHynds, Robert E.; Huebner, Ariana; Pearce, David R.; Hil, Mark S.; Akarca, Ayse U.; Moore, David A.; Ward, Sophia; Gowers, Kate H. C.; Karasaki, Takahiro; Al Bakir, Maise; Wilson, Gareth A.; Pich, Oriol; Martinez-Ruiz, Carlos; Hossain, A. S. Md Mukarram; Pearce, Simon P.; Sivakumar, Monica; Ben Aissa, Assma; Gronroos, Eva; Chandrasekharan, Deepak; Kolluri, Krishna K.; Towns, Rebecca; Wang, Kaiwen; Cook, Daniel E.; Bosshard-Carter, Leticia; Naceur-Lombardelli, Cristina; Rowan, Andrew J.; Veeriah, Selvaraju; Litchfield, Kevin; Crosbie, Philip A. J.; Dive, Caroline; Quezada, Sergio A.; Janes, Sam M.; Jamal-Hanjani, Mariam; Marafioti, Teresa; McGranahan, Nicholas; Swanton, Charles
err分享
err收藏
CRISPR-Cas9 Screening Identifies KRAS-Induced COX2 as a Driver of Immunotherapy Resistance in Lung CancerCRISPR-Cas9筛查确定KRAS诱导的COX2是肺癌免疫治疗耐药的驱动因素
errCANCER RESEARCH
IF16.6
err2024-04-18
err1
errOAAI
errBoumelha, Jesse; de Castro, Andrea; Bah, Nourdine; Cha, Hongui; Trecesson, Sophie de Carne; Rana, Sareena; Tomaschko, Mona; Anastasiou, Panayiotis; Mugarza, Edurne; Moore, Christopher; Goldstone, Robert; East, Phil; Litchfield, Kevin; Lee, Se-Hoon; Molina-Arcas, Miriam; Downward, Julian
err分享
err收藏
Drivers of immunotherapy response within the CPI3000+cohort
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errThakkar, Krupa; Castro, Andrea; Qian, Danwen; Swanton, Charles; Litchfield, Kevin
err分享
err收藏
Integration of innate and adaptive immune signatures for early detection of cancer
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errFitzsimons, Evelyn; Coulton, Alexander; Fu, Hongchang; Augustine, Marcellus; Lee, Richard; Reading, James; Litchfield, Kevin
err分享
err收藏
Identifying new immunotherapy targets using machine learning and ex vivo validation
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errAugustine, Marcellus; Nene, Nuno Rocha; Thakkar, Krupa; Qian, Danwen; Fitzsimons, Evelyn; Simpson, Benjamin S.; Watkins, Chris; Swanton, Charles; Litchfield, Kevin
err分享
err收藏
Pharmacologic modulation of nonsense-mediated decay induces antitumor immunogenicity in ex vivo patient tumors
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errVendramin, Roberto; Fu, Hongchang; Zhao, Yue; Fernandez-Patel, Shanila; Qian, Danwen; Ligammari, Lorena; Beattie, Gordon; Levy, Ronen; Greenberg, Polina; Bartok, Osnat; Thakkar, Krupa; Murai, Jun; Karagianni, Despoina; Sng, Chris; Shah, Mansi; Galvez-Cancino, Felipe; Djikstra, Krijn; Quezada, Sergio; Samuels, Yardena; Reading, James; Swanton, Charles; Litchfield, Kevin
err分享
err收藏
Integrated analysis of genetic, transcriptional and TME evolution of ccRCC: TRACERx RenalccRCC的遗传，转录和TME进化的综合分析: TRACERx肾脏
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errSanroman, Angel Fernandez; Au, Lewis; Tan, Benjy Jek Yang; Spencer, Charlotte; Catin, Anne-Laure; Lobon, Irene; Pallikonda, Husayn; Litchfield, Kevin; Byrne, Fiona; Larkin, James; Fendler, Annika; Turajlic, Samra
err分享
err收藏
Pervasive HLA disruption fuels cancer evolution
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errPuttick, Clare; Jones, Thomas P.; Leung, Michelle; Pich, Oriol; Cancino, Felipe Galvez; Liu, Jiali; Varas-Godoy, Manuel; Rowan, Andrew; Martinez-Ruiz, Carlos; Bentham, Robert; Dijkstra, Krijn K.; Rosenthal, Rachel; Kanu, Nnennaya; Litchfield, Kevin; Salgado, Roberto; Moore, David A.; Van Loo, Peter; Jamal-Hanjani, Mariam; Quezada, Sergio A.; McGranahan, Nicholas; Swanton, Charles
err分享
err收藏
Biomarkers of response and acquired resistance to TIL-ACT in solid tumors
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errRobinson, Welles; Castro, Andrea; Al-Bakir, Maise; Gartner, Jared J.; Chamberlain, Christopher Aled; Kverneland, Anders H.; Borch, Troels H.; Svane, Inge Marie; Donia, Marco; Robbins, Paul; Litchfield, Kevin
err分享
err收藏

研究方向

暂时未获取到该数据
合作学者
合作期刊
D
Douglas F. Easton
H 指数: 177 · 论文数: 1.2K
J
Jedd D. Wolchok
H 指数: 173 · 论文数: 1.4K
S
Stephen J. Chanock
H 指数: 170 · 论文数: 2.2K
P
P. Andrew Futreal
H 指数: 159 · 论文数: 1.3K
C
Carlos Caldas
H 指数: 158 · 论文数: 1.4K
查看更多