James G. Krueger - Publications, H-index & Citations

James G. Krueger

Rockefeller University

143H指数

746论文数

6.7W被引数

收录论文 424

发表时间

Systemic single-cell analysis of GPP reveals treatment-responsive and persistent immune signatures GPP的系统单细胞分析揭示了治疗反应性和持续性免疫特征

Clinical and Translational Medicine

IF6.8

2026-08-04

OAAI

Soyoung Jeong; Seungbok Lee; Christine Suh-Yun Joh; James G. Krueger; Hyun Je Kim; Seong Jin Jo; Jong-Hee Chae

Cutaneous adipose tissue carries a strong inflammatory signature in patients with psoriasis 银屑病患者皮肤脂肪组织具有强烈的炎症特征

JCI Insight

IF6.1

2026-04-08

PREAI

Shishido-Takahashi, Naomi; Garcet, Sandra; Cueto, Inna; Hur, Hong Beom; Muscianisi, Elisa; Steadman, Jennifer; Blauvelt, Andrew; Krueger, James G.

Molecular, Histological, and Clinical Effects of Selective TYK2 Inhibition with Zasocitinib (TAK-279) in Patients with Moderate-to-Severe Plaque Psoriasis 选择性TYK2抑制（使用Zasocitinib（TAK-279））在患有中重度斑块状银屑病患者中的分子、组织学和临床效果

Journal of Investigative Dermatology

IF5.7

2025-12-11

OAAI

Amit Choudhury; Sandra Garcet; Inna Cueto; Norma Kunjravia; Xuan Li; Darshna Rambhia; Sachin Kumar; Vinayagam Arunachalam; Jessamyn Blau; Jie Cheng; Feng Hong; Banishree Saha; Jay Tang; Wenwen Zhang; Håkan Wennbo; Paresh Thakker; James G. Krueger

Large-Scale Blood Proteomic Analysis Across Different Inflammatory Skin Conditions Reveals Extensive Immune Dysregulation With Distinct Biomarker Profiles 大规模血液蛋白质组学分析跨越不同炎症性皮肤疾病揭示广泛性免疫失调及独特的生物标志物谱系

Allergy

IF12

2025-11-17

PREAI

Jacob W. Glickman; Eden David; Neda Shokrian; Kelly Hawkins; Ester Del Duca; Benjamin D. Hu; Kristina Navrazhina; Britta Carroll; Arnav Mishra; Yeriel D. Estrada; Giselle Singer; James G. Krueger; Emma Guttman-Yassky

Bimekizumab Efficacy in Psoriasis by Subgroups: Post Hoc Analysis of Phase 3/3b Clinical Trials Bimekizumab在银屑病中的疗效：基于3期/3b期临床试验的亚组后分析

Dermatology and Therapy

IF4.2

2025-10-08

OAAI

Bruce Strober; Wolf-Henning Boehncke; James G. Krueger; Nina Magnolo; Ronald Vender; Richard B. Warren; José Manuel López Pinto; Sarah Kavanagh; Bengt Hoepken; Paolo Gisondi

A Functional Genetic Score in the ZMIZ1/TGF-β/STAT Pathway Predicts Early Biologic Discontinuation in Psoriasis Patients Treated with Anti-TNF and Anti-IL12/23 Agents ZMIZ1/TGF-β/STAT通路中的一个功能性遗传评分可预测接受抗TNF和抗IL12/23药物治疗的银屑病患者的早期生物制剂停用情况

Advances in Therapy

IF4

2025-10-06

PREAI

Juan de Luque; Carmen Mochón-Jiménez; Irene Rivera-Ruiz; Jesús Gay-Mimbrera; Judilyn Fuentes-Duculan; Israel Coats; Macarena Aguilar-Luque; Beatriz Isla-Tejera; Antonio Vélez-García Nieto; Manuel Galán-Gutiérrez; Teresa López-Viñau López; Mayte Suarez-Fariñas; James G. Krueger; Juan Ruano

SPECTREM phase IIIb clinical trial results through week 16: guselkumab efficacy and safety for the treatment of low body surface area, moderate psoriasis with high-impact site involvement SPECTREM IIIb期临床 trial 结果（16周）：guselkumab 治疗低体表面积、中度银屑病伴高影响部位受累的疗效与安全性

BRITISH JOURNAL OF DERMATOLOGY

IF9.6

2025-10-01

OAAI

Gold, Linda Stein; Gottlieb, Alice B.; Armstrong, April W.; Alkousakis, Theodore; Bissonnette, Robert; Langley, Richard G.; Krueger, James; Papp, Kim; Choi, Olivia; Rowland, Katelyn; Chan, Daphne; Jeyarajah, Jenny; Park-Wyllie, Laura; Gao, Long-Long; Gordon, Kenneth B.; Merola, Joseph F.; Lebwohl, Mark G.; Strober, Bruce

Molecular Profile of Interleukin-17RA Blockade by Brodalumab in Japanese Patients with Psoriasis: Results from the ESPRIT Study Brodalumab在日本银屑病患者中阻断白细胞介素-17RA的分子特征：ESPRIT研究的结果

Journal of Dermatological Science

IF4

2025-09-26

PREAI

James G. Krueger; Akimichi Morita; Mona Uchida-Yamada; Chiharu Tateishi; Eisaku Ogawa; Koji Masuda; Yukie Yamaguchi; Hong Beom Hur; Sandra Garcet; Naomi Shishido-Takahashi; Yasumasa Kanai

IL-17C as a Driver of Inflammation in Psoriasis IL-17C作为银屑病炎症的驱动因子

Advances in Therapy

IF4

2025-09-23

PREAI

George Han; April Armstrong; James G. Krueger; Abby Jacobson

Orismilast, a Potent and Selective PDE4B/D Inhibitor, Reduces Protein Levels of Key Disease Driving Cytokines in the Skin of Patients With Plaque Psoriasis 奥利司他酯（Orismilast），一种强效且选择性的PDE4B/D抑制剂，可降低斑块状银屑病患者皮肤中关键疾病驱动细胞因子的蛋白水平。

EXPERIMENTAL DERMATOLOGY

IF3.1

2025-09-19

OAAI

Warren, Richard B.; Weiss, Anne; Felding, Jakob; Sommer, Morten O. A.; Garcet, Sandra; Krueger, James G.

MicroRNA-223 expression during flares in patients with generalized pustular psoriasis is regulated by spesolimab treatment 泛发性脓疱型银屑病患者在发作期间MicroRNA-223的表达由spesolimab治疗调控

Journal of Investigative Dermatology

IF5.7

2025-08-28

OAAI

Denis Delić; Marcel Rolser; Christian T. Wohnhaas; Janine Roy; Kolja Becker; Anjli Kukreja; Christian Thoma; James G. Krueger

Comparative molecular analysis of IL-17A and IL-23 pathway inhibition in moderate-to-severe psoriasis: 4-week results from IXORA-R 中重度银屑病中IL-17A与IL-23通路抑制的分子比较分析：IXORA-R研究4周结果

Journal of Investigative Dermatology

IF5.7

2025-08-15

PREAI

Sandra Garcet; Lam C. Tsoi; Hong Hur; Andrew Blauvelt; Kim A. Papp; Bruce Konicek; Zhe Sun; Richard E. Higgs; Ernst R. Dow; David C. Gemperline; Gaia Gallo; Hany Elmaraghy; Brian J. Nickoloff; Venkatesh Krishnan; James G. Krueger; Johann E. Gudjonsson

A basophil-fibroblast pro-inflammatory axis fuels type 2 skin inflammation 嗜碱性粒细胞-成纤维细胞促炎轴驱动2型皮肤炎症

Cell Reports

IF6.9

2025-08-07

OAAI

Ichiro Imanishi; Raman Gill; Alexis Wilder; Paula Restrepo; Arjun Nair; Inchul Cho; James G. Krueger; Emma Guttman-Yassky; Brian S. Kim; Andrew L. Ji

Differential Effects of RORγ Inhibition on Selected Pathways in Plaque Psoriasis RORγ抑制对斑块状银屑病中选定通路的不同影响

Journal of Investigative Dermatology

IF5.7

2025-07-17

OAAI

Denis Delic; Sudha Visvanathan; Dongxia Xing; Janine Roy; Ramona Schmid; Richard Vinisko; Mary Flack; James G. Krueger

Single-cell transcriptomic analysis of GPP patients treated with IL-12/23 or IL-17A blockade GPP患者接受IL-12/23或IL-17A阻断治疗后的单细胞转录组分析

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

IF8

2025-03-25

PREAI

Soyoung Jeong; Christine Suh-Yun Joh; Seungbok Lee; James G. Krueger; Jong-Hee Chae; Hyun Je Kim; Seong Jin Jo

Guselkumab binding to CD64+ IL-23-producing myeloid cells enhances potency for neutralizing IL-23 signaling Guselkumab结合CD64+ IL-23产生髓系细胞，增强了中和IL-23信号的能力

FRONTIERS IN IMMUNOLOGY

IF5.9

2025-03-12

OAAI

Sachen, Kacey L.; Hammaker, Deepa; Sarabia, Indra; Stoveken, Brian; Hartman, John; Leppard, Kristin L.; Manieri, Nicholas A.; Bao, Phuc; Greving, Carrie; Lacy, Eilyn R.; Duprie, Matthew; Wertheimer, Joshua; Deming, Janise D.; Brown, Joseph; Hart, Amy; Li, He (Hurley); Freeman, Tom C.; Keyes, Brice; Kohler, Kristen; White, Ian; Karpowich, Nathan; Steele, Ruth; Elloso, M. Merle; Fakharzadeh, Steven; Goyal, Kavitha; Lavie, Frederic; Abreu, Maria T.; Allez, Matthieu; Atreya, Raja; Bissonnette, Robert; Eyerich, Kilian; Krueger, James G.; Mcgonagle, Dennis; Mcinnes, Iain B.; Ritchlin, Christopher; Fourie, Anne M.

Hepatocyte Growth Factor Has Unique Functions in Keratinocytes that Differ from those of IL-17A and TNF and May Contribute to Inflammatory Pathways in Hidradenitis 肝细胞生长因子在角质形成细胞中具有不同于IL-17A和TNF的独特功能，可能有助于汗腺炎的炎症途径

JOURNAL OF INVESTIGATIVE DERMATOLOGY

IF5.7

2025-03-01

PREAI

Shishido-Takahashi, Naomi; Garcet, Sandra; Cueto, Inna; Miura, Shunsuke; Li, Xuan; Rambhia, Darshna; Kunjravia, Norma; Hur, Hong Beom; Lee, Young In; Ham, Seoyoon; Anis, Nabeeha; Kim, Jaehwan; Krueger, James G.

Spesolimab Reduces Inflammation in Generalized Pustular Psoriasis: Molecular Characterization of Flare Treatment in EFFISAYIL 1 Spesolimab可减轻泛发性脓疱性牛皮癣的炎症: EFFISAYIL 1中Flare治疗的分子特征

JOURNAL OF INVESTIGATIVE DERMATOLOGY

IF5.7

2025-03-01

PREAI

Farag, Ahmed; Visvanathan, Sudha; Bachelez, Herve; Morita, Akimichi; Lebwohl, Mark G.; Barker, Jonathan N.; Choon, Siew Eng; Burden, A. David; Tsai, Tsen-Fang; Leparc, German; Delic, Denis; Lang, Benjamin; Thoma, Christian; Krueger, James G.

Psoriasis harbors multiple pathogenic type 17 T-cell subsets: Selective modulation by risankizumab 银屑病包含多种致病性第17型T细胞亚群： risankizumab的选择性调节

Journal of Allergy and Clinical Immunology

IF11.2

2025-02-18

OAAI

Jaehwan Kim; Jongmi Lee; Jongeun Lee; Katherine Kim; Xuan Li; Wei Zhou; Junyue Cao; James G. Krueger

Skin immune-mesenchymal interplay within tertiarylymphoid structures promotes autoimmunepathogenesis in hidradenitis suppurativa HS患者三级淋巴样结构中皮肤免疫-间质细胞间的相互作用促进了自身免疫病的发生发展。

IMMUNITY

IF26.3

2024-12-01

PREAI

Yu, Wei-Wen; Barrett, Joy N. P.; Tong, Jie; Lin, Meng-Ju; Marohn, Meaghan; Devlin, Joseph C.; Herrera, Alberto; Remark, Juliana; Levine, Jamie; Liu, Pei-Kang; Fang, Victoria; Zellmer, Abigail M.; Oldridge, Derek A.; Wherry, E. John; Lin, Jia-Ren; Chen, Jia-Yun; Sorger, Peter; Santagata, Sandro; Krueger, James G.; Ruggles, Kelly, V; Wang, Fei; Su, Chang; Koralov, Sergei B.; Wang, Jun; Chiu, Ernest S.; Lu, Catherine P.

研究方向