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H

Hin Chu

University of Hong Kong
H指数:61
被引数:3.1万

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Cattle and human organoids reveal 2.3.4.4b H5N1 cross-species transmission potential and neuraminidase-specific neutralizing antibodies in humans

牛和人类类器官揭示2.3.4.4b H5N1的跨种传播潜力及神经氨酸酶特异性中和抗体在人体中的存在

Nature Communications
IF15.7
2026-07-080
OAAI
Cun Li; Yifei Yu; Zhixin Wan; Jian-Piao Cai; Jingjing Huang; Xiaoxin Zhu; Jiali Wu; Wei Xue; Ying Zhou; Man Chun Chiu; Qiaoshuai Lan; Shuxin Zhang; Zijun Zhao; Yidong Yang; Yuhong Liu; Pui Wang; Shaofeng Deng; Ming Yue; Longchao Zhu; Keshan Zhang; Mengmeng Zhao; Jieshi Yu; Wenkang Wei; Xiang Gao; Lin Huang; Hin Chu; Gang Wu; Honglin Chen; Kwok Yung Yuen; Richard Webby; Jie Zhou
Human angiotensin‑converting enzyme 2‑specific benzothiazole-based allosteric inhibitor against pan‑sarbecoviruses

人血管紧张素‑转化酶2特异性苯并噻唑基别构抑制剂对泛沙贝科病毒的作用

Nature Communications
IF15.7
2026-06-060
OAAI
Li Liu; Jinxin Bai; Runhong Zhou; Yao Ma; Dongyan Zhou; Terrence Tsz-Tai Yuen; Wenwu Liu; Pok Man Lai; Wenjun Yu; Jianxin Duan; Jingjia Ye; Xinhua Liu; Ruomei Gong; Ka-Yi Kwan; Tsz Tung Lee; Feifei Liu; Zhenglong Du; Pui Wang; Mengxiao Luo; Dawei Yang; Kong Hung Sze; Hin Chu; Zhiwei Chen; Gang Liu
YL1004 is a SARS-CoV-2 papain-like protease inhibitor with immunomodulatory and antiviral activity in mice

YL1004是一种SARS-CoV-2的木瓜蛋白酶样蛋白酶抑制剂，在小鼠中具有免疫调节和抗病毒活性

Nature Communications
IF15.7
2026-01-260
OA
Jinshan Nan; Huiping Shuai; Jingxin Qiao; Rui Zeng; Lianzhao Du; Yan Chen; Chaemin Yoon; Jiaheng Hu; Wenyu Guo; Lei Wang; Chong Huang; Lengjing Zhu; Yueshan Li; Shanshan Zhang; Xinyue Deng; Jingxuan Sun; Le Du; Ronggang Ma; Qiao Huang; Jian Lei; Hin Chu; Shengyong Yang
Author Correction: An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo

作者更正：一种口服可用的Mpro/TMPRSS2双特异性抑制剂，具有体内强效抗冠状病毒疗效

Nature Communications
IF15.7
2025-12-150
OAAI
Huiping Shuai; Jingxin Qiao; Chaemin Yoon; Guo Zhang; Yuxin Hou; Xiaoyan Xia; Lei Wang; Xinyue Deng; Yifei Wang; Qingquan Li; Lianzhao Du; Yuanchen Liu; Minmin Zhou; Hoi Ting Wong; Jiaheng Hu; Huan Liu; Bingjie Hu; Dong Wang; Jingyi Su; Yuying Pan; Yongtao Ye; Yan Chen; Zhen Fang; Ziyi Xia; Yue Chai; Jialu Shi; Yang Wang; Tianrenzheng Zhu; Honglei Zhang; Shuofeng Yuan; Jie Zhou; Jasper Fuk-Woo Chan; Kwok-Yung Yuen; Chunfu Xu; Jian Lei; Shengyong Yang; Hin Chu
Pathogenicity, virological features, and immune evasion of SARS-CoV-2 JN.1-derived variants including JN.1.7, KP.2, KP.3, and KP.3.1.1

SARS-CoV-2 JN.1衍生变体 (包括JN.1.7、KP.2、KP.3和KP.3.1.1) 的致病性、病毒学特征和免疫逃避

Nature Communications
IF15.7
2025-12-110
OAAI
Jialu Shi; Xiaoyu Zhao; Xiaohui Jin; Jiayan Li; Yuanchen Liu; Huan Liu; Ye-Fan Hu; Zhe Chen; Yuxin Xiao; Lei Wang; Yajie Wang; Yixin He; Yue Chai; Bingjie Hu; Huiping Shuai; Yang Wang; Xiangnan Li; Shujun Jiang; Yanliang Zhang; Xiaojuan Zhang; Wan-Mui Chan; Lin-Lei Chen; Jian-Piao Cai; Baokun Sui; Honglei Zhang; Dong Yang; Longchao Zhu; Shuofeng Yuan; Jie Zhou; Jian-Dong Huang; Kwok-Yung Yuen; Kelvin Kai-Wang To; Jasper Fuk-Woo Chan; Bao-Zhong Zhang; Qiao Wang; Maozhou He; Lei Sun; Pengfei Wang; Hin Chu
An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo

一种口服可用的Mpro/TMPRSS2双特异性抑制剂，具有体内强效抗冠状病毒活性

Nature Communications
IF15.7
2025-07-160
OA
Huiping Shuai; Jingxin Qiao; Chaemin Yoon; Guo Zhang; Yuxin Hou; Xiaoyan Xia; Lei Wang; Xinyue Deng; Yifei Wang; Qingquan Li; Lianzhao Du; Yuanchen Liu; Minmin Zhou; Hoi Ting Wong; Jiaheng Hu; Huan Liu; Bingjie Hu; Dong Wang; Jingyi Su; Yuying Pan; Yongtao Ye; Yan Chen; Zhen Fang; Ziyi Xia; Yue Chai; Jialu Shi; Yang Wang; Tianrenzheng Zhu; Honglei Zhang; Shuofeng Yuan; Jie Zhou; Jasper Fuk-Woo Chan; Kwok-Yung Yuen; Chunfu Xu; Jian Lei; Shengyong Yang; Hin Chu
Reverse genetics-derived cattle H5N1 virus from Clade 2.3.4.4b shows enhanced systemic infectivity and pathogenicity than an older Clade 1 H5N1 virus in BALB/c mice

反向遗传学衍生的2.3.4.4b分支牛源H5N1病毒在小鼠中表现出比更早的1分支H5N1病毒更强的系统性感染力和致病性。

EMERGING MICROBES & INFECTIONS
IF7.5
2025-03-170
OAAI
Na Xiao; Xiang Yong Oong; Yanxia Chen; Can Li; Howard Chun-Ho Chung; Pui Wang; Zhanhong Ye; Alvin Hiu-Chung Lam; Jianpiao Cai; Wenchen Song; Andrew Chak-Yiu Lee; Hin Chu; Kin-Hang Kok; Jasper Fuk-Woo Chan; Shuofeng Yuan; Honglin Chen; Kwok-Yung Yuen; Anna Jin-Xia Zhang
Lineage-specific pathogenicity, immune evasion, and virological features of SARS-CoV-2 BA.2.86/JN.1 and EG.5.1/HK.3

SARS-CoV-2 BA.2.86/JN.1和EG.5.1/HK.3的谱系特异性致病性，免疫逃逸和病毒学特征

NATURE COMMUNICATIONS
IF15.7
2024-10-091
OAAI
Liu, Yuanchen; Zhao, Xiaoyu; Shi, Jialu; Wang, Yajie; Liu, Huan; Hu, Ye-Fan; Hu, Bingjie; Shuai, Huiping; Yuen, Terrence Tsz-Tai; Chai, Yue; Liu, Feifei; Gong, Hua-Rui; Li, Jiayan; Wang, Xun; Jiang, Shujun; Zhang, Xiang; Zhang, Yanliang; Li, Xiangnan; Wang, Lei; Hartnoll, Madeline; Zhu, Tianrenzheng; Hou, Yuxin; Huang, Xiner; Yoon, Chaemin; Wang, Yang; He, Yixin; Zhou, Minmin; Du, Lianzhao; Zhang, Xiaojuan; Chan, Wan-Mui; Chen, Lin-Lei; Cai, Jian-Piao; Yuan, Shuofeng; Zhou, Jie; Huang, Jian-Dong; Yuen, Kwok-Yung; To, Kelvin Kai-Wang; Chan, Jasper Fuk-Woo; Zhang, Bao-Zhong; Sun, Lei; Wang, Pengfei; Chu, Hin
Virological characteristics of a SARS-CoV-2-related bat coronavirus, BANAL-20-236
EBIOMEDICINE
IF10.8
2024-06-011
OAAI
Fujita, Shigeru; Plianchaisuk, Arnon; Deguchi, Sayaka; Ito, Hayato; Nao, Naganori; Wang, Lei; Nasser, Hesham; Tamura, Tomokazu; Kimura, Izumi; Kashima, Yukie; Suzuki, Rigel; Suzuki, Saori; Kida, Izumi; Tsuda, Masumi; Oda, Yoshitaka; Hashimoto, Rina; Watanabe, Yukio; Uriu, Keiya; Yamasoba, Daichi; Guo, Ziyi; Hinay, Alfredo A., Jr.; Kosugi, Yusuke; Chen, Luo; Pan, Lin; Kaku, Yu; Chu, Hin; Donati, Flora; Temmam, Sarah; Eloit, Marc; Yamamoto, Yuki; Nagamoto, Tetsuharu; Asakura, Hiroyuki; Sadamasu, Kenji; Yoshimura, Kazuhisa; Suzuki, Yutaka; Ito, Jumpei; Ikeda, Terumasa; Nagashima, Mami; Tanaka, Shinya; Matsuno, Keita; Fukuhara, Takasuke; Takayama, Kazuo; Sato, Kei

研究方向

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K
Kwok‐Yung Yuen
H 指数:161论文数:1,729被引数:16.6万
S
Shuofeng Yuan
H 指数:49论文数:235被引数:2.6万
J
Jasper Fuk‐Woo Chan
H 指数:102论文数:680被引数:6.8万
J
Jian‐Piao Cai
H 指数:57论文数:243被引数:2.6万
K
Kelvin Kai‐Wang To
H 指数:88论文数:496被引数:5.5万
J
Jie Zhou
H 指数:54论文数:217被引数:1.1万
J
Jinxia Zhang
H 指数:52论文数:182被引数:1.2万
J
Jasper Fuk‐Woo Chan
H 指数:0论文数:12被引数:86
C
Cun Li
H 指数:32论文数:97被引数:5,029
V
Vincent Kwok‐Man Poon
H 指数:51论文数:124被引数:2.0万