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H

Hin Chu

The University of Hong Kong

61H指数
231论文数
3.1W被引数
收录论文 142
发表时间
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Organoid-based evaluation of SA55 and Pemivibart against evolving SARS-CoV-2 variants基于类器官的SA55和Pemivibart对不断演变的SARS-CoV-2变种的评估
errEmerging Microbes & Infections
IF0
err2026-08-12
err0
errOAAI
errZhixin Wan; Ying Zhou; Fanchong Jian; Jiali Wu; Wei Xue; Man Chun Chiu; Yifei Yu; Qiaoshuai Lan; Shuxin Zhang; Zijun Zhao; Xiaoxin Zhu; Jingjing Huang; Yidong Yang; Yuhong Liu; Xinjie Meng; Lin Huang; Xiang Gao; Hin Chu; Cun Li; Yunlong Cao; Jie Zhou
err分享
err收藏
Host transcriptional corepressor TLE1 is commonly exploited by RNA viruses for replication宿主转录辅抑制因子TLE1常被RNA病毒利用以进行复制
errMolecular Cell
IF16.6
err2026-07-21
err0
errOAAI
errXiaomeng Yang; Haoran Sun; Peng Luo; Kailai Li; Tong-Yun Wang; Qian Guo; Hehe Cao; Xiaoyang Shu; Bo Qin; Min Guo; Ming Yan; Kun Huang; Jiahui Zou; Zi-Wei Ye; Hin Chu; Jasper Fuk-Woo Chan; Dong-Yan Jin; Bi Shi; Sheng Cui; Honglin Chen
err分享
err收藏
Cattle and human organoids reveal 2.3.4.4b H5N1 cross-species transmission potential and neuraminidase-specific neutralizing antibodies in humans牛和人类类器官揭示2.3.4.4b H5N1的跨种传播潜力及神经氨酸酶特异性中和抗体在人体中的存在
errNature Communications
IF15.7
err2026-07-08
err0
errOAAI
errCun Li; Yifei Yu; Zhixin Wan; Jian-Piao Cai; Jingjing Huang; Xiaoxin Zhu; Jiali Wu; Wei Xue; Ying Zhou; Man Chun Chiu; Qiaoshuai Lan; Shuxin Zhang; Zijun Zhao; Yidong Yang; Yuhong Liu; Pui Wang; Shaofeng Deng; Ming Yue; Longchao Zhu; Keshan Zhang; Mengmeng Zhao; Jieshi Yu; Wenkang Wei; Xiang Gao; Lin Huang; Hin Chu; Gang Wu; Honglin Chen; Kwok Yung Yuen; Richard Webby; Jie Zhou
err分享
err收藏
Human angiotensin‑converting enzyme 2‑specific benzothiazole-based allosteric inhibitor against pan‑sarbecoviruses人血管紧张素‑转化酶2特异性苯并噻唑基别构抑制剂对泛沙贝科病毒的作用
errNature Communications
IF15.7
err2026-06-06
err0
errOAAI
errLi Liu; Jinxin Bai; Runhong Zhou; Yao Ma; Dongyan Zhou; Terrence Tsz-Tai Yuen; Wenwu Liu; Pok Man Lai; Wenjun Yu; Jianxin Duan; Jingjia Ye; Xinhua Liu; Ruomei Gong; Ka-Yi Kwan; Tsz Tung Lee; Feifei Liu; Zhenglong Du; Pui Wang; Mengxiao Luo; Dawei Yang; Kong Hung Sze; Hin Chu; Zhiwei Chen; Gang Liu
err分享
err收藏
YL1004 is a SARS-CoV-2 papain-like protease inhibitor with immunomodulatory and antiviral activity in miceYL1004是一种SARS-CoV-2的木瓜蛋白酶样蛋白酶抑制剂，在小鼠中具有免疫调节和抗病毒活性
errNature Communications
IF15.7
err2026-01-26
err0
errOAAI
errJinshan Nan; Huiping Shuai; Jingxin Qiao; Rui Zeng; Lianzhao Du; Yan Chen; Chaemin Yoon; Jiaheng Hu; Wenyu Guo; Lei Wang; Chong Huang; Lengjing Zhu; Yueshan Li; Shanshan Zhang; Xinyue Deng; Jingxuan Sun; Le Du; Ronggang Ma; Qiao Huang; Jian Lei; Hin Chu; Shengyong Yang
err分享
err收藏
Author Correction: An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo作者更正：一种口服可用的Mpro/TMPRSS2双特异性抑制剂，具有体内强效抗冠状病毒疗效
errNature Communications
IF15.7
err2025-12-15
err0
errOAAI
errHuiping Shuai; Jingxin Qiao; Chaemin Yoon; Guo Zhang; Yuxin Hou; Xiaoyan Xia; Lei Wang; Xinyue Deng; Yifei Wang; Qingquan Li; Lianzhao Du; Yuanchen Liu; Minmin Zhou; Hoi Ting Wong; Jiaheng Hu; Huan Liu; Bingjie Hu; Dong Wang; Jingyi Su; Yuying Pan; Yongtao Ye; Yan Chen; Zhen Fang; Ziyi Xia; Yue Chai; Jialu Shi; Yang Wang; Tianrenzheng Zhu; Honglei Zhang; Shuofeng Yuan; Jie Zhou; Jasper Fuk-Woo Chan; Kwok-Yung Yuen; Chunfu Xu; Jian Lei; Shengyong Yang; Hin Chu
err分享
err收藏
Pathogenicity, virological features, and immune evasion of SARS-CoV-2 JN.1-derived variants including JN.1.7, KP.2, KP.3, and KP.3.1.1SARS-CoV-2 JN.1衍生变体 (包括JN.1.7、KP.2、KP.3和KP.3.1.1) 的致病性、病毒学特征和免疫逃避
errNature Communications
IF15.7
err2025-12-11
err0
errOAAI
errJialu Shi; Xiaoyu Zhao; Xiaohui Jin; Jiayan Li; Yuanchen Liu; Huan Liu; Ye-Fan Hu; Zhe Chen; Yuxin Xiao; Lei Wang; Yajie Wang; Yixin He; Yue Chai; Bingjie Hu; Huiping Shuai; Yang Wang; Xiangnan Li; Shujun Jiang; Yanliang Zhang; Xiaojuan Zhang; Wan-Mui Chan; Lin-Lei Chen; Jian-Piao Cai; Baokun Sui; Honglei Zhang; Dong Yang; Longchao Zhu; Shuofeng Yuan; Jie Zhou; Jian-Dong Huang; Kwok-Yung Yuen; Kelvin Kai-Wang To; Jasper Fuk-Woo Chan; Bao-Zhong Zhang; Qiao Wang; Maozhou He; Lei Sun; Pengfei Wang; Hin Chu
err分享
err收藏
Identification of Cathepsin L as the molecular target of hydroxychloroquine with chemical proteomics利用化学蛋白质组学鉴定半胱天冬酶L为羟氯喹的分子靶点
errMolecular & Cellular Proteomics
IF5.5
err2025-10-18
err0
errOAAI
errJin Shang; Bingjie Hu; Ka-Yan Karen Kung; Jiajun Jiang; Qi Zhang; Man-Kin Wong; Hin Chu; Qian Zhao
err分享
err收藏
An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo一种口服可用的Mpro/TMPRSS2双特异性抑制剂，具有体内强效抗冠状病毒活性
errNature Communications
IF15.7
err2025-07-16
err0
errOAAI
errHuiping Shuai; Jingxin Qiao; Chaemin Yoon; Guo Zhang; Yuxin Hou; Xiaoyan Xia; Lei Wang; Xinyue Deng; Yifei Wang; Qingquan Li; Lianzhao Du; Yuanchen Liu; Minmin Zhou; Hoi Ting Wong; Jiaheng Hu; Huan Liu; Bingjie Hu; Dong Wang; Jingyi Su; Yuying Pan; Yongtao Ye; Yan Chen; Zhen Fang; Ziyi Xia; Yue Chai; Jialu Shi; Yang Wang; Tianrenzheng Zhu; Honglei Zhang; Shuofeng Yuan; Jie Zhou; Jasper Fuk-Woo Chan; Kwok-Yung Yuen; Chunfu Xu; Jian Lei; Shengyong Yang; Hin Chu
err分享
err收藏
PIM1 Attenuates Innate Immunity to Foster Coronavirus Replication through Ubiquitin Ligase β-TrCP-Mediated IFNAR1 DegradationPIM1通过泛素连接酶β-TrCP介导的IFNAR1降解来减弱固有免疫，从而促进冠状病毒复制。
errAdvanced Science
IF14.1
err2025-07-06
err0
errOAAI
errQianya Wan; Lin Zhu; Cien Chen; Li Zhong; Houying Leung; Wei Li; Chang Xu; Xi Yao; Huan Hu; Mandi Wu; Yuxin Hou; Hin Chu; Yiran Wang; Sheng Chen; Mingyu Pan
err分享
err收藏
Reverse genetics-derived cattle H5N1 virus from Clade 2.3.4.4b shows enhanced systemic infectivity and pathogenicity than an older Clade 1 H5N1 virus in BALB/c mice反向遗传学衍生的2.3.4.4b分支牛源H5N1病毒在小鼠中表现出比更早的1分支H5N1病毒更强的系统性感染力和致病性。
errEMERGING MICROBES & INFECTIONS
IF7.5
err2025-03-17
err0
errOAAI
errNa Xiao; Xiang Yong Oong; Yanxia Chen; Can Li; Howard Chun-Ho Chung; Pui Wang; Zhanhong Ye; Alvin Hiu-Chung Lam; Jianpiao Cai; Wenchen Song; Andrew Chak-Yiu Lee; Hin Chu; Kin-Hang Kok; Jasper Fuk-Woo Chan; Shuofeng Yuan; Honglin Chen; Kwok-Yung Yuen; Anna Jin-Xia Zhang
err分享
err收藏
Potent and broadly neutralizing antibodies against sarbecoviruses elicited by single ancestral SARS-CoV-2 infection
errCOMMUNICATIONS BIOLOGY
IF5.1
err2025-03-06
err0
errOAAI
errYu, Lei; Wang, Yajie; Liu, Yuanchen; Xing, Xiaomin; Li, Chen; Wang, Xun; Shi, Jialu; Ma, Wentai; Li, Jiayan; Chen, Yanjia; Qiao, Rui; Zhao, Xiaoyu; Tian, Shilei; Gao, Ming; Wen, Shuhua; Xue, Yingxue; Qiu, Tianyi; Yu, Hongjie; Guan, Yongjun; Chu, Hin; Sun, Lei; Wang, Pengfei
err分享
err收藏
Lineage-specific pathogenicity, immune evasion, and virological features of SARS-CoV-2 BA.2.86/JN.1 and EG.5.1/HK.3SARS-CoV-2 BA.2.86/JN.1和EG.5.1/HK.3的谱系特异性致病性，免疫逃逸和病毒学特征
errNATURE COMMUNICATIONS
IF15.7
err2024-10-09
err1
errOAAI
errLiu, Yuanchen; Zhao, Xiaoyu; Shi, Jialu; Wang, Yajie; Liu, Huan; Hu, Ye-Fan; Hu, Bingjie; Shuai, Huiping; Yuen, Terrence Tsz-Tai; Chai, Yue; Liu, Feifei; Gong, Hua-Rui; Li, Jiayan; Wang, Xun; Jiang, Shujun; Zhang, Xiang; Zhang, Yanliang; Li, Xiangnan; Wang, Lei; Hartnoll, Madeline; Zhu, Tianrenzheng; Hou, Yuxin; Huang, Xiner; Yoon, Chaemin; Wang, Yang; He, Yixin; Zhou, Minmin; Du, Lianzhao; Zhang, Xiaojuan; Chan, Wan-Mui; Chen, Lin-Lei; Cai, Jian-Piao; Yuan, Shuofeng; Zhou, Jie; Huang, Jian-Dong; Yuen, Kwok-Yung; To, Kelvin Kai-Wang; Chan, Jasper Fuk-Woo; Zhang, Bao-Zhong; Sun, Lei; Wang, Pengfei; Chu, Hin
err分享
err收藏
Chronic lung inflammation and CK14+ basal cell proliferation induce persistent alveolar-bronchiolization in SARS-CoV-2infected hamsters
errEBIOMEDICINE
IF10.8
err2024-10-01
err0
errOAAI
errLi, Can; Xiao, Na; Song, Wenchen; Lam, Alvin Hiu-Chung; Liu, Feifei; Cui, Xinrui; Ye, Zhanhong; Chen, Yanxia; Ren, Peidi; Cai, Jianpiao; Lee, Andrew Chak-Yiu; Chen, Honglin; Ou, Zhihua; Chan, Jasper Fuk-Woo; Yuen, Kwok-Yung; Chu, Hin; Zhang, Anna Jin-Xia
err分享
err收藏
Bispecific antibodies provide broad neutralization of emerging beta-coronaviruses by targeting ACE2 and viral spikes
errEMERGING MICROBES & INFECTIONS
IF7.5
err2024-09-22
err0
errOAAI
errLi, Minghui; Zhao, Chaoyue; Shi, Jialu; Wang, Xun; Liu, Yuanchen; Zhao, Xiaoyu; Cai, Guonan; Chu, Hin; Wang, Pengfei
err分享
err收藏
Virological characteristics of a SARS-CoV-2-related bat coronavirus, BANAL-20-236
errEBIOMEDICINE
IF10.8
err2024-06-01
err1
errOAAI
errFujita, Shigeru; Plianchaisuk, Arnon; Deguchi, Sayaka; Ito, Hayato; Nao, Naganori; Wang, Lei; Nasser, Hesham; Tamura, Tomokazu; Kimura, Izumi; Kashima, Yukie; Suzuki, Rigel; Suzuki, Saori; Kida, Izumi; Tsuda, Masumi; Oda, Yoshitaka; Hashimoto, Rina; Watanabe, Yukio; Uriu, Keiya; Yamasoba, Daichi; Guo, Ziyi; Hinay, Alfredo A., Jr.; Kosugi, Yusuke; Chen, Luo; Pan, Lin; Kaku, Yu; Chu, Hin; Donati, Flora; Temmam, Sarah; Eloit, Marc; Yamamoto, Yuki; Nagamoto, Tetsuharu; Asakura, Hiroyuki; Sadamasu, Kenji; Yoshimura, Kazuhisa; Suzuki, Yutaka; Ito, Jumpei; Ikeda, Terumasa; Nagashima, Mami; Tanaka, Shinya; Matsuno, Keita; Fukuhara, Takasuke; Takayama, Kazuo; Sato, Kei
err分享
err收藏
Impact of Secondary Organic Aerosol on the Respiratory Viral Infection in Vitro
errENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS
IF8.8
err2024-05-14
err0
PREAI
errWang, Shunyao; Zhang, Xi; Lin, Kaisen; Huang, Guanwen; Zhao, Yue; Chu, Hin; Chan, Arthur W. H.
err分享
err收藏
COVID-19 drug discovery and treatment options
errNATURE REVIEWS MICROBIOLOGY
IF103.3
err2024-04-15
err12
PREAI
errChan, Jasper Fuk-Woo; Yuan, Shuofeng; Chu, Hin; Sridhar, Siddharth; Yuen, Kwok-Yung
err分享
err收藏
PMI-controlled mannose metabolism and glycosylation determines tissue tolerance and virus fitness
errNATURE COMMUNICATIONS
IF15.7
err2024-03-08
err2
errOAAI
errLiang, Ronghui; Ye, Zi-Wei; Qin, Zhenzhi; Xie, Yubin; Yang, Xiaomeng; Sun, Haoran; Du, Qiaohui; Luo, Peng; Tang, Kaiming; Hu, Bodan; Cao, Jianli; Wong, Xavier Hoi-Leong; Ling, Guang-Sheng; Chu, Hin; Shen, Jiangang; Yin, Feifei; Jin, Dong-Yan; Chan, Jasper Fuk-Woo; Yuen, Kwok-Yung; Yuan, Shuofeng
err分享
err收藏
Type-II IFN inhibits SARS-CoV-2 replication in human lung epithelial cells and ex vivo human lung tissues through indoleamine 2,3-dioxygenase-mediated pathways
errJOURNAL OF MEDICAL VIROLOGY
IF4.6
err2024-02-19
err2
errOAAI
errYang, Dong; Chan, Jasper Fuk-Woo; Yoon, Chaemin; Luk, Tsz-Yat; Shuai, Huiping; Hou, Yuxin; Huang, Xiner; Hu, Bingjie; Chai, Yue; Yuen, Terrence Tsz-Tai; Liu, Yuanchen; Zhu, Tianrenzheng; Liu, Huan; Shi, Jialu; Wang, Yang; He, Yixin; Sit, Ko-Yung; Au, Wing-Kuk; Zhang, Anna Jinxia; Yuan, Shuofeng; Zhang, Bao-Zhong; Huang, Yao-Wei; Chu, Hin
err分享
err收藏

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合作学者
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Josef Penninger
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Chi‐Ming Che
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Pak C. Sham
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