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J

Jacob D. Estes

oregon health & science university
H指数:76
被引数:2.2万

个人简介

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教育背景

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工作经历

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荣誉奖项

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SIV reservoir depletion and clearance from neonatal macaques following transient CCR5 depletion

SIV储库在短暂CCR5耗竭后从新生儿恒河猴中的耗竭与清除

Nature Microbiology
IF19.4
2026-10-190
OAAI
Jesse D. Deere; David Merriam; Kawthar Machmach; W. L. William Chang; Michael Nekorchuk; Gema Méndez-Lagares; Hung Kieu; Joseph Dutra; Justin Fontaine; Denise R. Andal; Kateland Sipe; Elizabeth Heninger; Margaret Martin; Wenze Lu; Ning Chin; Connie Chen; Bryant Chi-Thien Tran; Jessica Salinas; Corey N. Miller; Steven G. Deeks; Jeffrey D. Lifson; Kathleen Engelman; Diogo Magnani; Keith Reimann; Mario Stevenson; Jacob D. Estes; Dennis J. Hartigan-O’Connor
First-line dolutegravir/lamivudine in HIV-1 infection: lymph node penetration and reservoir decline in a randomized open-label clinical trial

HIV-1感染中一线多替拉韦/拉米夫定治疗：一项随机开放标签临床试验中的淋巴结渗透和病毒库下降

Nature Communications
IF15.7
2026-10-020
OA
Elias P. Rosen; Stephen Bondoc; Lucía Bailón; Lidia Blay; Albert Caballero; Maria C. García-Guerrero; Maria C. Puertas; Igor Moraes-Cardoso; Andrea Vazquez-Escobales; Julià Blanco; Beatriz Mothe; Angela DM Kashuba; Jacob D. Estes; Javier Martinez-Picado; Jose Molto
Distinct phases of immune system programming during ART-suppressed immunodeficiency virus infection

在抗逆转录病毒疗法抑制的免疫缺陷病毒感染期间免疫系统编程的不同阶段

Cell Reports
IF6.9
2026-09-300
OAAI
Maanasa Kaza; Benjamin Varco-Merth; G.W. McElfresh; Sebastian Benjamin; Gregory J. Boggy; Morgan Chaunzwa; Shana Feltham; Sohita Ojha; Karina Belica; Andrea N. Selseth; Michael Nekorchuk; Kathleen Busman-Sahay; Brandon F. Keele; Dan H. Barouch; Jeffrey D. Lifson; Jacob D. Estes; Scott G. Hansen; Afam A. Okoye; Louis J. Picker; Benjamin N. Bimber
Contribution of intact viral genomes persisting in blood and tissues during ART to plasma viral rebound in SHIV-infected rhesus macaques

在ART治疗期间，持续存在于血液和组织中的完整病毒基因组对SHIV感染恒河猴血浆病毒反弹的贡献

ISCIENCE
IF4.1
2025-03-010
OAAI
Trifone, Cesar; Richard, Corentin; Pagliuzza, Amelie; Dufour, Caroline; Lemieux, Audree; Clark, Natasha M.; Janaka, Sanath K.; Fennessey, Christine M.; Keele, Brandon E.; Fromentin, Remi; Estes, Jacob D.; Kaufmann, Daniel E.; Finzi, Andres; Evans, David T.; Chomont, Nicolas
Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption (vol 25, pg 1900, 2024)

IL-10和PD-1的双阻断导致分析性治疗中断后SIV病毒反弹得到控制（卷25，页1900，2024）

NATURE IMMUNOLOGY
IF27.6
2025-01-160
OA
Pereira Ribeiro, Susan; Strongin, Zachary; Soudeyns, Hugo; ten-Caten, Felipe; Ghneim, Khader; Pacheco Sanchez, Gabriela; Xavier de Medeiros, Giuliana; Del Rio Estrada, Perla Mariana; Pelletier, Adam-Nicolas; Hoang, Timothy; Nguyen, Kevin; Harper, Justin; Jean, Sherrie; Wallace, Chelsea; Balderas, Robert; Lifson, Jeffrey D.; Raghunathan, Gopalan; Rimmer, Eric; Pastuskovas, Cinthia V.; Wu, Guoxin; Micci, Luca; Ribeiro, Ruy M.; Chan, Chi Ngai; Estes, Jacob D.; Silvestri, Guido; Gorman, Daniel M.; Howell, Bonnie J.; Hazuda, Daria J.; Paiardini, Mirko; Sekaly, Rafick P.
Impact of Dolutegravir Plus Lamivudine as First-line Antiretroviral Treatment on the Human Immunodeficiency Virus Type 1 Reservoir and Inflammatory Markers in Peripheral Blood

度鲁特韦联合拉米夫定一线抗逆转录病毒治疗对外周血人类免疫缺陷病病毒1型储库和炎症标志物的影响

JOURNAL OF INFECTIOUS DISEASES
IF4.5
2024-10-280
PRE
Bailon, Lucia; Puertas, Maria C.; Garcia-Guerrero, Maria C.; Moraes-Cardoso, Igor; Aparicio, Ester; Alarcon-Soto, Yovaninna; Rivero, Angel; Rosen, Elias P.; Estes, Jacob D.; Blanco, Julia; Olvera, Alex; Mothe, Beatriz; Martinez-Picado, Javier; Molto, Jose
Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption
NATURE IMMUNOLOGY
IF27.6
2024-09-122
OAAI
Pereira Ribeiro, Susan; Strongin, Zachary; Soudeyns, Hugo; ten-Caten, Felipe; Ghneim, Khader; Pacheco Sanchez, Gabriela; Xavier de Medeiros, Giuliana; Del Rio Estrada, Perla Mariana; Pelletier, Adam-Nicolas; Hoang, Timothy; Nguyen, Kevin; Harper, Justin; Jean, Sherrie; Wallace, Chelsea; Balderas, Robert; Lifson, Jeffrey D.; Raghunathan, Gopalan; Rimmer, Eric; Pastuskova, Cinthia; Wu, Guoxin; Micci, Luca; Ribeiro, Ruy M.; Chan, Chi Ngai; Estes, Jacob D.; Silvestri, Guido; Gorman, Daniel M.; Howell, Bonnie J.; Hazuda, Daria J.; Paiardini, Mirko; Sekaly, Rafick P.
Regional Analysis of Intact and Defective HIV Proviruses in the Brain of Viremic and Virally Suppressed People with HIV

病毒病和病毒抑制的HIV感染者大脑中完整和有缺陷的HIV前病毒的区域分析

ANNALS OF NEUROLOGY
IF7.7
2023-08-1213
OAAI
Angelovich, Thomas A.; Cochrane, Catherine R.; Zhou, Jingling; Tumpach, Carolin; Byrnes, Sarah J.; Eddine, Janna Jamal; Waring, Emily; Busman-Sahay, Kathleen; Deleage, Claire; Jenkins, Trisha A.; Hearps, Anna C.; Turville, Stuart; Gorry, Paul R.; Lewin, Sharon R.; Brew, Bruce J.; Estes, Jacob D.; Roche, Michael; Churchill, Melissa J.
Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques
SCIENCE IMMUNOLOGY
IF16.3
2023-07-2811
OA
Viox, Elise G.; Hoang, Timothy N.; Upadhyay, Amit A.; Nchioua, Rayhane; Hirschenberger, Maximilian; Strongin, Zachary; Tharp, Gregory K.; Pino, Maria; Nguyen, Kevin; Harper, Justin L.; Gagne, Matthew; Marciano, Shir; Boddapati, Arun K.; Pellegrini, Kathryn L.; Pradhan, Arpan; Tisoncik-Go, Jennifer; Whitmore, Leanne S.; Karunakaran, Kirti A.; Roy, Melissa; Kirejczyk, Shannon; Curran, Elizabeth H.; Wallace, Chelsea; Wood, Jennifer S.; Connor-Stroud, Fawn; Voigt, Emily A.; Monaco, Christopher M.; Gordon, David E.; Kasturi, Sudhir P.; Levit, Rebecca D.; Gale, Michael; Vanderford, Thomas H.; Silvestri, Guido; Busman-Sahay, Kathleen; Estes, Jacob D.; Vaccari, Monica; Douek, Daniel C.; Sparrer, Konstantin M. J.; Johnson, R. Paul; Kirchhoff, Frank; Schreiber, Gideon; Bosinger, Steven E.; Paiardini, Mirko
Allogeneic immunity clears latent virus following allogeneic stem cell transplantation in SIV-infected ART-suppressed macaques
IMMUNITY
IF26.3
2023-07-0115
OA
Wu, Helen L.; Busman-Sahay, Kathleen; Weber, Whitney C.; Waytashek, Courtney M.; Boyle, Carla D.; Bateman, Katherine B.; Reed, Jason S.; Hwang, Joseph M.; Shriver-Munsch, Christine; Swanson, Tonya; Northrup, Mina; Armantrout, Kimberly; Price, Heidi; Robertson-LeVay, Mitch; Uttke, Samantha; Kumar, Mithra R.; Fray, Emily J.; Taylor-Brill, Sol; Bondoc, Stephen; Agnor, Rebecca; Junell, Stephanie L.; Legasse, Alfred W.; Moats, Cassandra; Bochart, Rachele M.; Sciurba, Joseph; Bimber, Benjamin N.; Sullivan, Michelle N.; Dozier, Brandy; MacAllister, Rhonda P.; Hobbs, Theodore R.; Martin, Lauren D.; Panoskaltsis-Mortari, Angela; Colgin, Lois M. A.; Siliciano, Robert F.; Siliciano, Janet D.; Estes, Jacob D.; Smedley, Jeremy V.; Axthelm, Michael K.; Meyers, Gabrielle; Maziarz, Richard T.; Burwitz, Benjamin J.; Stanton, Jeffrey J.; Sacha, Jonah B.
Lymph-Node-Based CD3+ CD20+ Cells Emerge from Membrane Exchange between T Follicular Helper Cells and B Cells and Increase Their Frequency following Simian Immunodeficiency Virus Infection
JOURNAL OF VIROLOGY
IF3.8
2023-06-293
OA
Samer, Sadia; Chowdhury, Ankita; Salinas, Tomas Raul Wiche; Estrada, Perla M. Del Rio; Reuter, Morgan; Tharp, Gregory; Bosinger, Steven; Cervasi, Barbara; Auger, James; Gill, Kiran; Ablanedo-Terrazas, Yuria; Reyes-Teran, Gustavo; Estes, Jacob D.; Betts, Michael R.; Silvestri, Guido; Paiardini, Mirko
Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques (vol 10, e1009565, 2021)
PLOS PATHOGENS
IF4.9
2023-04-190
OAAI
Bochart, Rachele M.; Busman-Sahay, Kathleen; Bondoc, Stephen; Morrow, David W.; Ortiz, Alexandra M.; Fennessey, Christine M.; Fischer, Miranda B.; Shiel, Oriene; Swanson, Tonya; Shriver-Munsch, Christine M.; Crank, Hugh B.; Armantrout, Kimberly M.; Barber-Axthelm, Aaron M.; Langner, Charlotte; Moats, Cassandra R.; Labriola, Caralyn S.; MacAllister, Rhonda; Axthelm, Michael K.; Brenchley, Jason M.; Keele, Brandon F.; Estes, Jacob D.; Hansen, Scott G.; Smedley, Jeremy V.
Chronic immune activation and gut barrier dysfunction is associated with neuroinflammation in ART-suppressed SIV plus rhesus macaques
PLOS PATHOGENS
IF4.9
2023-03-297
OAAI
Byrnes, Sarah J.; Busman-Sahay, Kathleen; Angelovich, Thomas A.; Younger, Skyler; Taylor-Brill, Sol; Nekorchuk, Michael; Bondoc, Stephen; Dannay, Rachel; Terry, Margaret; Cochrane, Catherine R.; Jenkins, Trisha A.; Roche, Michael; Deleage, Claire; Bosinger, Steven E.; Paiardini, Mirko; Brew, Bruce J.; Estes, Jacob D.; Churchill, Melissa J.
In-depth virological and immunological characterization of HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation
NATURE MEDICINE
IF50
2023-02-2086
OAAI
Jensen, Bjoern-Erik Ole; Knops, Elena; Cords, Leon; Luebke, Nadine; Salgado, Maria; Busman-Sahay, Kathleen; Estes, Jacob D. D.; Huyveneers, Laura E. P.; Perdomo-Celis, Federico; Wittner, Melanie; Galvez, Cristina; Mummert, Christiane; Passaes, Caroline; Eberhard, Johanna M. M.; Muenk, Carsten; Hauber, Ilona; Hauber, Joachim; Heger, Eva; De Clercq, Jozefien; Vandekerckhove, Linos; Bergmann, Silke; Dunay, Gabor A.; Klein, Florian; Haeussinger, Dieter; Fischer, Johannes C. C.; Nachtkamp, Kathrin; Timm, Joerg; Kaiser, Rolf; Harrer, Thomas; Luedde, Tom; Nijhuis, Monique; Saez-Cirion, Asier; Wiesch, Julian Schulze zur; Wensing, Annemarie M. J.; Martinez-Picado, Javier; Kobbe, Guido

研究方向

暂未获取到该数据
C
Claire Deléage
H 指数:33论文数:114被引数:5,303
J
Jeffrey D. Lifson
H 指数:109论文数:544被引数:4.5万
K
Kathleen Busman‐Sahay
H 指数:23论文数:60被引数:3,218
G
Guido Silvestri
H 指数:81论文数:419被引数:2.7万
M
Mirko Paiardini
H 指数:55论文数:227被引数:1.1万
J
Jeremy Smedley
H 指数:31论文数:118被引数:2,953
J
Jason M. Brenchley
H 指数:86论文数:278被引数:3.7万
A
Ashley T. Haase
H 指数:88论文数:269被引数:3.3万
D
Daniel C. Douek
H 指数:137论文数:598被引数:7.4万
G
Gregory Q. Del Prete
H 指数:29论文数:70被引数:3,332