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Glycosylated carbon nanodots as multivalent blockers of lectin-driven viral entry: structural insights and antiviral performance 糖基化碳纳米点作为凝集素驱动的病毒进入的多价阻断剂:结构见解和抗病毒性能 Nieto-Ortiz, Gema; Cabrera-Gonzalez, Justo; Lasala, Fatima; Rodriguez-Perez, Laura; Valdivieso Gonzalez, David; Lopez-Montero, Ivan; Delgado, Rafael; Martin, Nazario; Herranz, M. Angeles; Illescas, Beatriz M. 分享 收藏
Dolutegravir/Lamivudine for Maintenance of Virological Suppression in Persons With Historical Suspected or Confirmed Resistance to Lamivudine: Week 48 Results of a Single-Arm, Open-Label, Multicenter, Phase IIa Clinical Trial De Miguel, Rosa; Sebastian, Maria de Lagarde; Arevalo, Jose Luis Blanco; Pinto-Martinez, Adriana; Montejano, Rocio; Liarte, Angela Gutierrez; Navarro-Soler, Roser; Canas-Ruano, Esperanza; Inciarte, Alexis; Martin-Carbonero, Luz; Imaz, Arkaitz; Gutierrez, Cristina Hernandez; Ocampo, Antonio; Divasson, Pedro Gil; Delgado, Rafael; Pulido, Federico; Arribas, Jose R. 分享 收藏
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Discovery of Thiophene Derivatives as Potent, Orally Bioavailable, and Blood-Brain Barrier-Permeable Ebola Virus Entry Inhibitors 噻吩衍生物作为有效的,口服生物可利用的和血脑屏障可渗透的埃博拉病毒进入抑制剂的发现 Morales-Tenorio, Marcos; Lasala, Fatima; Garcia-Rubia, Alfonso; Aledavood, Elnaz; Heung, Michelle; Olal, Catherine; Escudero-Perez, Beatriz; Alonso, Covadonga; Martinez, Ana; Munoz-Fontela, Cesar; Delgado, Rafael; Gil, Carmen 分享 收藏
MVA-based vaccine candidates expressing SARS-CoV-2 prefusion-stabilized spike proteins of the Wuhan, Beta or Omicron BA.1 variants protect transgenic K18-hACE2 mice against Omicron infection and elicit robust and broad specific humoral and cellular immune responses Perez, Patricia; Astorgano, David; Albericio, Guillermo; Flores, Sara; Sanchez-Corzo, Cristina; Noriega, Maria A.; Sanchez-Cordon, Pedro J.; Labiod, Nuria; Delgado, Rafael; Casasnovas, Jose M.; Esteban, Mariano; Garcia-Arriaza, Juan 分享 收藏
Prevalence and Phenotypic Susceptibility to Doravirine of the HIV-1 Reverse Transcriptase V106I Polymorphism in B and Non-B Subtypes Giammarino, Federica; de Salazar, Adolfo; Malet, Isabelle; Vinuela, Laura; Fuentes, Ana; Saladini, Francesco; Bartolini, Niccolo; Charpentier, Charlotte; Lambert-Niclot, Sidonie; Sterrantino, Gaetana; Colao, Maria Grazia; Micheli, Valeria; Bertoli, Ada; Fabeni, Lavinia; Teyssou, Elisa; Delgado, Rafael; Falces-Romero, Iker; Aguilera, Antonio; Gomes, Perpetua; Paraskevis, Dimitrios; Santoro, Maria M.; Ceccherini-Silberstein, Francesca; Marcelin, Anne-Genevieve; Moreno, Cristina; Zazzi, Maurizio; Garcia, Federico 分享 收藏
Unprecedented selectivity for homologous lectin targets: differential targeting of the viral receptors L-SIGN and DC-SIGN Delaunay, Clara; Pollastri, Sara; Thepaut, Michel; Cavazzoli, Gianluca; Belvisi, Laura; Bouchikri, Clementine; Labiod, Nuria; Lasala, Fatima; Gimeno, Ana; Franconetti, Antonio; Jimenez-Barbero, Jesus; Arda, Ana; Delgado, Rafael; Bernardi, Anna; Fieschi, Franck 分享 收藏
MAFB shapes human monocyte-derived macrophage response to SARS-CoV-2 and controls severe COVID-19 biomarker expression Simon-Fuentes, Miriam; Rios, Israel; Herrero, Cristina; Lasala, Fatima; Labiod, Nuria; Luczkowiak, Joanna; Roy-Vallejo, Emilia; Cordoba-Onate, Sara Fernandez de; Delgado-Wicke, Pablo; Bustos, Matilde; Fernandez-Ruiz, Elena; Colmenares, Maria; Puig-Kroeger, Amaya; Delgado, Rafael; Vega, Miguel A.; Corbi, angel L.; Dominguez-Soto, Angeles 分享 收藏
C60-based Multivalent Glycoporphyrins Inhibit SARS-CoV-2 Specific Interaction with the DC-SIGN Transmembrane Receptor Patino-Alonso, Jennifer; Cabrera-Gonzalez, Justo; Merino, Javier; Nieto-Ortiz, Gema; Lasala, Fatima; Katati, Jouma; da Cruz, Carlos H. Bezerra; Monnappa, Ajay K.; Mateos-Gil, Pablo; Canales, Angeles; Lopez-Montero, Ivan; Illescas, Beatriz M.; Delgado, Rafael; Martin, Nazario 分享 收藏
Preclinical immune efficacy against SARS-CoV-2 beta B.1.351 variant by MVA-based vaccine candidates Perez, Patricia; Albericio, Guillermo; Astorgano, David; Flores, Sara; Sanchez-Corzo, Cristina; Sanchez-Cordon, Pedro J.; Luczkowiak, Joanna; Delgado, Rafael; Casasnovas, Jose M.; Esteban, Mariano; Garcia-Arriaza, Juan 分享 收藏
Superior neutralizing response after first versus second SARS-CoV-2 infection in fully vaccinated individuals Rivas, Gonzalo; Labiod, Nuria; Luczkowiak, Joanna; Lasala, Fatima; Rolo, Marta; Mancheno-Losa, Mikel; Rial-Crestelo, David; Lora-Tamayo, Jaime; Perez-Rivilla, Alfredo; Dolores Folgueira, Maria; Delgado, Rafael 分享 收藏
Dendritic Cell-Mediated Cross-Priming by a Bispecific Neutralizing Antibody Boosts Cytotoxic T Cell Responses and Protects Mice against SARS-CoV-2 双特异性中和抗体介导的树突状细胞介导的交叉引发可增强细胞毒性T细胞反应并保护小鼠免受SARS-CoV-2 Lazaro-Gorines, Rodrigo; Perez, Patricia; Heras-Murillo, Ignacio; Adan-Barrientos, Irene; Albericio, Guillermo; Astorgano, David; Flores, Sara; Luczkowiak, Joanna; Labiod, Nuria; Harwood, Seandean L.; Segura-Tudela, Alejandro; Rubio-Perez, Laura; Nugraha, Yudhi; Shang, Xiaoran; Li, Yuxing; Alfonso, Carlos; Adipietro, Kaylin A.; Abeyawardhane, Dinendra L.; Navarro, Rocio; Compte, Marta; Yu, Wenbo; Mackerell, Alexander D.; Sanz, Laura; Weber, David J.; Blanco, Francisco J.; Esteban, Mariano; Pozharski, Edwin; Godoy-Ruiz, Raquel; Munoz, Ines G.; Delgado, Rafael; Sancho, David; Garcia-Arriaza, Juan; Alvarez-Vallina, Luis 分享 收藏
Optimized vaccine candidate MVA-S(3P) fully protects against SARS-CoV-2 infection in hamsters Abdelnabi, Rana; Perez, Patricia; Astorgano, David; Albericio, Guillermo; Kerstens, Winnie; Thibaut, Hendrik Jan; Coelmont, Lotte; Weynand, Birgit; Labiod, Nuria; Delgado, Rafael; Montenegro, Dolores; Puentes, Eugenia; Rodriguez, Esteban; Neyts, Johan; Dallmeier, Kai; Esteban, Mariano; Garcia-Arriaza, Juan 分享 收藏
Clinical outcomes and antibody transfer in a cohort of infants with in utero or perinatal exposure to SARS-CoV-2 (Coronascope Study) Colom, Jaime Carrasco; Manzanares, Angela; Gomez, Alicia Alvaro; Escribano, Isabel Serrano; Esquivel, Estrella; Perez-Rivilla, Alfredo; Moral-Pumarega, Maria Teresa; Pascual, Elisa Aguirre; De Vergas, Joaquin; del Barrio, Sara Reda; Moraleda, Cinta; Epalza, Cristina; Fernandez-Cooke, Elisa; Prieto, Luis; Villaverde, Serena; Zamora, Berta; Herraiz, Ignacio; Galindo, Alberto; Folgueira, Maria Dolores; Delgado, Rafael; Blazquez-Gamero, Daniel 分享 收藏
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Expert Consensus: Main Risk Factors for Poor Prognosis in COVID-19 and the Implications for Targeted Measures against SARS-CoV-2 Candel, Francisco Javier; Barreiro, Pablo; Salavert, Miguel; Cabello, Alfonso; Fernandez-Ruiz, Mario; Perez-Segura, Pedro; San Roman, Jesus; Berenguer, Juan; Cordoba, Raul; Delgado, Rafael; Espana, Pedro Pablo; Gomez-Centurion, Ignacio Alberto; del Castillo, Juan Maria Gonzalez; Heili, Sarah Beatrice; Martinez-Peromingo, Francisco Javier; Menendez, Rosario; Moreno, Santiago; Pablos, Jose Luis; Pasquau, Juan; Pinana, Jose Luis 分享 收藏
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N?-Phenylacetohydrazide Derivatives as Potent Ebola Virus Entry Inhibitors with an Improved Pharmacokinetic Profile N?-苯基乙酰肼衍生物作为有效的埃博拉病毒进入抑制剂,具有改善的药代动力学特征 Garcia-Rubia, Alfonso; Lasala, Fatima; Ginex, Tiziana; Morales-Tenorio, Marcos; Olal, Catherine; Heung, Michelle; Oquist, Paola; Galindo, Inmaculada; Cuesta-Geijo, Miguel Aprimengel; Casasnovas, Jose M.; Campillo, Nuria E.; Canales, Angeles; Alonso, Covadonga; Martinez, Ana; Munoz-Fontela, Cesar; Delgado, Rafael; Gil, Carmen 分享 收藏