Aurélie Cobat

Hôpital Necker-Enfants Malades

H指数:53

被引数:1.6万

个人简介

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教育背景

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工作经历

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荣誉奖项

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Prediction of human missense variant effects from functional evidence

基于功能证据预测人类错义变异的影响

Nature Genetics

IF29

2026-08-260

PRE

Human LFA-1 governs T cell immune surveillance of the skin

人LFA-1调控T细胞对皮肤的免疫监视

Science Immunology

IF16.3

2026-02-270

PRE

Ahmad Yatim; Leila Youssefian; Aida Idani; Haralambos Mourelatos; Nasrin Alipour Olyaei; Laleh Habibi; Jessica N. Peel; Maira Gaballa; Colin Kim; Danyel Lee; Corentin Le Floc’h; Yi-Hao Chan; Marta Martin-Fernandez; Léo Pelletier; Koji Nakajima; Antoine Fayand; Mana Momenilandi; Yoann Seeleuthner; Matthieu Chaldebas; Amir Hossein Saeidian; Hamidreza Mahmoudi; Neda Nikbakht; Caroline Deswarte; Nesrine Kerrouche; Houria Sahel; Nima Parvaneh; Banafshe Tamizifar; Roya Sherkat; Johan Chanal; Alireza Firooz; Zahra Alizadeh; Lazaro Lorenzo-Diaz; Alice-Andrée Mariaggi; Masato Ogishi; Antoine Diep; Boualem Hammadi; Nacim Kerrouche; Darawan Rinchai; Sahar Sedighzadeh; Soophia Mehrjooy; Seyed Mohammad Akrami; Cedric Lenormand; Mirjana Radosavljevic; Jérémie Rosain; Shen-Ying Zhang; Bertrand Boisson; Peng Zhang; Stéphanie Boisson-Dupuis; James G. Krueger; Jean-Luc Prétet; Tim Waterboer; Zahra Pourpak; Mohammad Reza Fazlollahi; Laurent Abel; Dusan Bogunovic; Mohammad Shahrooei; Aurélie Cobat; Raphael Carapito; Anne Molitor; Hassan Vahidnezhad; Vivien Béziat; Seiamak Bahram; Emmanuelle Jouanguy; Jean-Laurent Casanova

Autoantibodies neutralizing type I IFNs in patients with fulminant herpes simplex virus hepatitis

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2025-12-051

PRE

Gervais, Adrian; Marchal, Astrid; Boucherit, Soraya; Abi Haidar, Anthony; Bizien, Lucy; Yalcinkaya, Ahmet; Sandstrom, Ella; Kong, Xiao-Fei; Jacquemin, Emmanuel; Bernard, Olivier; Debray, Dominique; Lacaille, Florence; Ichai, Philippe; Arikan, Cigdem; Javouhey, Etienne; Roquelaure, Bertrand; Gottrand, Frederic; Trespidi, Francesca; Codullo, Veronica; Cavagna, Lorenzo; Schleinitz, Nicolas; Bousfiha, Mohamed; Amenzoui, Naima; Bousfiha, Ahmed Aziz; Jorgensen, Sofie E.; Mork, Nanna; Mogensen, Trine H.; Bastard, Paul; Puel, Anne; Borghesi, Alessandro; Rule, Jody A.; Lee, William M.; Landegren, Nils; Cobat, Aurelie; Casanova, Jean-Laurent; Jouanguy, Emmanuelle

Autoantibodies neutralizing type I IFNs in a fatal case of H5N1 avian influenza

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2025-12-050

Deleterious variants in the autophagy-related gene RB1CC1/FIP200 impair immunity to SARS-CoV-2

自噬相关基因RB1CC1/FIP200的有害变异损害了对SARS-CoV-2的免疫力

Nature Communications

IF15.7

2025-11-270

OAAI

MosCoverY: A method to estimate mosaic loss of Y chromosome from sequencing coverage data

MosCoverY: 一种基于测序覆盖度数据估计Y染色体嵌合丢失的方法

american journal of human genetics

IF0

2025-09-110

OAAI

Exome-based genotype-first reverse phenotyping using structured electronic health record data identifies novel SERPINA1 variants associated with liver markers and demonstrates a dominant effect for specific variants on liver phenotype

基于外显子组学的基因分型优先逆向表型分析，利用结构化电子健康记录数据，识别出与肝脏标志物相关的SERPINA1新变异，并证实特定变异对肝脏表型具有显性效应。

HEPATOLOGY RESEARCH

IF3.4

2025-05-130

Response to Karp-Tatham et al.

对karp-tatham等人的回应。

HUMAN GENETICS AND GENOMICS ADVANCES

IF3.6

2025-04-010

OAAI

Therapeutic plasma exchange accelerates immune cell recovery in severe COVID-19

FRONTIERS IN IMMUNOLOGY

IF5.9

2025-01-170

OAAI

具有或不具有中和I型干扰素的自身抗体的新型冠状病毒肺炎肺炎的重症监护病房患者的肺SARS-CoV-2负荷动力学相似

JOURNAL OF CLINICAL IMMUNOLOGY

IF5.7

2024-11-200

PRE

Auto-Abs neutralizing type I IFNs in patients with severe Powassan, Usutu, or Ross River virus disease

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2024-11-010

OAAI

Gervais, Adrian; Bastard, Paul; Bizien, Lucy; Delifer, Celine; Tiberghien, Pierre; Rodrigo, Chaturaka; Trespidi, Francesca; Angelini, Micol; Rossini, Giada; Lazzarotto, Tiziana; Conti, Francesca; Cassaniti, Irene; Baldanti, Fausto; Rovida, Francesca; Ferrari, Alessandro; Mileto, Davide; Mancon, Alessandro; Abel, Laurent; Puel, Anne; Cobat, Aurelie; Rice, Charles M.; Cadar, Daniel; Schmidt-Chanasit, Jonas; Scheid, Johannes F.; Lemieux, Jacob E.; Rosenberg, Eric S.; Agudelo, Marianna; Tangye, Stuart G.; Borghesi, Alessandro; Durand, Guillaume Andre; Duburcq-Gury, Emilie; Valencia, Braulio M.; Lloyd, Andrew R.; Nagy, Anna; MacDonald, Margaret M.; Simonin, Yannick; Zhang, Shen-Ying; Casanova, Jean-Laurent

Incontinentia pigmenti underlies thymic dysplasia, autoantibodies to type I IFNs, and viral diseases

色素失禁是胸腺发育不良，I型ifn自身抗体和病毒性疾病的基础

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2024-10-011

OAAI

Rosain, Jeremie; Le Voyer, Tom; Liu, Xian; Gervais, Adrian; Polivka, Laura; Cederholm, Axel; Berteloot, Laureline; Parent, Audrey V.; Pescatore, Alessandra; Spinosa, Ezia; Minic, Snezana; Kiszewski, Ana Elisa; Tsumura, Miyuki; Thibault, Chloe; Azcoiti, Maria Esnaola; Martinovic, Jelena; Philippot, Quentin; Khan, Taushif; Marchal, Astrid; Charmeteau-De Muylder, Benedicte; Bizien, Lucy; Deswarte, Caroline; Hadjem, Lillia; Fauvarque, Marie-Odile; Dorgham, Karim; Eriksson, Daniel; Falcone, Emilia Liana; Puel, Mathilde; Uenal, Sinem; Geraldo, Amyrath; Le Floc'h, Corentin; Li, Hailun; Rheault, Sylvie; Muti, Christine; Bobrie-Moyrand, Claire; Welfringer-Morin, Anne; Fuleihan, Ramsay L.; Levy, Romain; Roelens, Marie; Gao, Liwei; Materna, Marie; Pellegrini, Silvia; Piemonti, Lorenzo; Catherinot, Emilie; Goffard, Jean-Christophe; Fekkar, Arnaud; Sacko-Sow, Aissata; Soudee, Camille; Boucherit, Soraya; Neehus, Anna-Lena; Has, Cristina; Huebner, Stefanie; Blanchard-Rohner, Geraldine; Amador-Borrero, Blanca; Utsumi, Takanori; Taniguchi, Maki; Tani, Hiroo; Izawa, Kazushi; Yasumi, Takahiro; Kanai, Sotaro; Migaud, Melanie; Aubart, Melodie; Lambert, Nathalie; Gorochov, Guy; Picard, Capucine; Soudais, Claire; L'Honneur, Anne-Sophie; Rozenberg, Flore; Milner, Joshua D.; Zhang, Shen-Ying; Vabres, Pierre; Trpinac, Dusan; Marr, Nico; Boddaert, Nathalie; Desguerre, Isabelle; Pasparakis, Manolis; Miller, Corey N.; Poziomczyk, Claudia S.; Abel, Laurent; Okada, Satoshi; Jouanguy, Emmanuelle; Cheynier, Remi; Zhang, Qian; Cobat, Aurelie; Beziat, Vivien; Boisson, Bertrand; Steffann, Julie; Fusco, Francesca; Ursini, Matilde Valeria; Hadj-Rabia, Smail; Bodemer, Christine; Bustamante, Jacinta; Luche, Herve; Puel, Anne; Courtois, Gilles; Bastard, Paul; Landegren, Nils; Anderson, Mark S.; Casanova, Jean-Laurent

Autoantibodies neutralizing type I IFNs underlie severe tick-borne encephalitis in ∼10% of patients

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2024-09-243

OAAI

Gervais, Adrian; Marchal, Astrid; Fortova, Andrea; Berankova, Michaela; Krbkova, Lenka; Pychova, Martina; Salat, Jiri; Zhao, Shuxiang; Kerrouche, Nacim; Le Voyer, Tom; Stiasny, Karin; Raffl, Simon; Schieber Pachart, Anne; Fafi-Kremer, Samira; Gravier, Simon; Robbiani, Davide F.; Abel, Laurent; MacDonald, Margaret R.; Rice, Charles M.; Weissmann, Gaia; Kamal Eldin, Tarek; Robatscher, Eva; Erne, Elke Maria; Pagani, Elisabetta; Borghesi, Alessandro; Puel, Anne; Bastard, Paul; Velay, Aurelie; Martinot, Martin; Hansmann, Yves; Aberle, Judith H.; Ruzek, Daniel; Cobat, Aurelie; Zhang, Shen-Ying; Casanova, Jean-Laurent

Gain-of-function human UNC93B1 variants cause systemic lupus erythematosus and chilblain lupus

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2024-06-1310

OAAI

David, Clemence; Arango-Franco, Carlos A.; Badonyi, Mihaly; Fouchet, Julien; Rice, Gillian I.; Didry-Barca, Blaise; Maisonneuve, Lucie; Seabra, Luis; Kechiche, Robin; Masson, Cecile; Cobat, Aurelie; Abel, Laurent; Talouarn, Estelle; Beziat, Vivien; Deswarte, Caroline; Livingstone, Katie; Paul, Carle; Malik, Gulshan; Ross, Alison; Adam, Jane; Walsh, Jo; Kumar, Sathish; Bonnet, Damien; Bodemer, Christine; Bader-Meunier, Brigitte; Marsh, Joseph A.; Casanova, Jean-Laurent; Crow, Yanick J.; Manoury, Benedicte; Fremond, Marie-Louise; Bohlen, Jonathan; Lepelley, Alice

In search of a function for human type III interferons: insights from inherited and acquired deficits

CURRENT OPINION IN IMMUNOLOGY

IF5.8

2024-04-012

PRE

An immunogenomic exome landscape of triple positive primary antiphospholipid patients (24 Jan, 10.1038/s41435-024-00255-w, 2024)

GENES AND IMMUNITY

IF4.5

2024-03-191

An immunogenomic exome landscape of triple positive primary antiphospholipid patients

GENES AND IMMUNITY

IF4.5

2024-01-240

Human autoantibodies neutralizing type I IFNs: From 1981 to 2023

中和I型ifn的人类自身抗体: 来自1981 2023年

IMMUNOLOGICAL REVIEWS

IF8.3

2024-01-0914

OAAI

The immunopathological landscape of human pre-TCRα deficiency: From rare to common variants

Science

IF45.8

2024-01-010

Marie Materna; Ottavia M. Delmonte; Marita Bosticardo; Mana Momenilandi; Peyton E. Conrey; Bénédicte Charmeteau-De Muylder; Clotilde Bravetti; Rebecca Bellworthy; Axel Cederholm; Frederik Staels; Christian A. Ganoza; Samuel W. Darko; Samir U. Sayed; Corentin Le Floc’h; Masato Ogishi; Darawan Rinchai; Andrea Guennoun; Alexandre Bolze; Taushif Khan; Adrian Gervais; Renate Krüger; Mirjam Völler; Boaz Palterer; Mahnaz Sadeghi‐Shabestari; Anne Langlois de Septenville; Chaim A. Schramm; Sanjana B. Shah; John James Tello Cajiao; Francesca Pala; Kayla Amini; Jose S. Campos; Noemia S. Lima; Daniel Eriksson; Romain Lévy; Yoann Seeleuthner; Soma C. Jyonouchi; Manar Ata; Fatima Al Ali; Caroline Deswarte; A B Pereira; Jérôme Megret; Tom Le Voyer; Paul Bastard; Laureline Berteloot; Michaël Dussiot; Natasha Vladikine; Paula P. Cárdenas; Emmanuelle Jouanguy; Mashael F. Alqahtani; Amal Hasan; Thangavel Alphonse Thanaraj; Jérémie Rosain; Fahd A. Al Qureshah; Vito Sabato; Marie Alexandra Alyanakian; Marianne Leruez‐Ville; Flore Rozenberg; Élie Haddad; José Ramón Regueiro; Marı́a L. Toribio; Judith R. Kelsen; Mansoor Salehi; Shahram Nasiri; Mehdi Torabizadeh; Hassan Rokni‐Zadeh; Majid Changi‐Ashtiani; Nasimeh Vatandoost; Hossein Moravej; Seyed Mohammad Akrami; Mohsen Mazloomrezaei; Aurélie Cobat; Isabelle Meyts; Etsushi Toyofuku; Madoka Nishimura; Kunihiko Moriya; Tomoyuki Mizukami; Kohsuke Imai; Laurent Abel; Bernard MALISSEN; Fahd Al‐Mulla; Fowzan Sami Alkuraya; Nima Parvaneh; Horst von Bernuth; Christian Beetz; Frédéric Davi; Daniel C. Douek; Rémi Cheynier; David Langlais; Nils Landegren; Nico Marr; Tomohiro Morio; Mohammad Shahrooei; Rik Schrijvers; Sarah Emily Henrickson; Hervé Luche; Luigi Daniele Notarangelo; Jean‐Laurent Casanova; Vivien Béziat

Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs neutralizing type I IFNs

Auto-abs中和I型干扰素患者的疫苗突破性低氧新型冠状病毒肺炎肺炎

SCIENCE IMMUNOLOGY

IF16.3

2023-12-2243

OAAI

Bastard, Paul; Vazquez, Sara; Liu, Jamin; Laurie, Matthew T.; Wang, Chung Yu; Gervais, Adrian; Le Voyer, Tom; Bizien, Lucy; Zamecnik, Colin; Philippot, Quentin; Rosain, Jeremie; Catherinot, Emilie; Willmore, Andrew; Mitchell, Anthea M.; Bair, Rebecca; Garcon, Pierre; Kenney, Heather; Fekkar, Arnaud; Salagianni, Maria; Poulakou, Garyphallia; Siouti, Eleni; Sahanic, Sabina; Tancevski, Ivan; Weiss, Gunter; Nagl, Laurenz; Manry, Jeremy; Duvlis, Sotirija; Arroyo-Sanchez, Daniel; Paz Artal, Estela; Rubio, Luis; Perani, Cristiano; Bezzi, Michela; Sottini, Alessandra; Quaresima, Virginia; Roussel, Lucie; Vinh, Donald C.; Felipe Reyes, Luis; Garzaro, Margaux; Hatipoglu, Nevin; Boutboul, David; Tandjaoui-Lambiotte, Yacine; Borghesi, Alessandro; Aliberti, Anna; Cassaniti, Irene; Venet, Fabienne; Monneret, Guillaume; Halwani, Rabih; Sharif-Askari, Narjes Saheb; Danielson, Jeffrey; Burrel, Sonia; Morbieu, Caroline; Stepanovskyy, Yurii; Bondarenko, Anastasia; Volokha, Alla; Boyarchuk, Oksana; Gagro, Alenka; Neuville, Mathilde; Neven, Benedicte; Keles, Sevgi; Hernu, Romain; Bal, Antonin; Novelli, Antonio; Novelli, Giuseppe; Saker, Kahina; Ailioaie, Oana; Antoli, Arnau; Jeziorski, Eric; Rocamora-Blanch, Gemma; Teixeira, Carla; Delaunay, Clarisse; Lhuillier, Marine; Le Turnier, Paul; Zhang, Yu; Mahevas, Matthieu; Pan-Hammarstrom, Qiang; Abolhassani, Hassan; Bompoil, Thierry; Dorgham, Karim; Group, French Covid Study; Gorochov, Guy; Laouenan, Cedric; Rodriguez-Gallego, Carlos; Ng, Lisa F. P.; Renia, Laurent; Pujol, Aurora; Belot, Alexandre; Raffi, Francois; Allende, Luis M.; Martinez-Picado, Javier; Ozcelik, Tayfun; Keles, Sevgi; Imberti, Luisa; Notarangelo, Luigi D.; Troya, Jesus; Solanich, Xavier; Zhang, Shen-Ying; Puel, Anne; Wilson, Michael R.; Trouillet-Assants, Sophie; Abe, Laurent; Jouanguy, Emmanuelle; Ye, Chun Jimmie; Cobat, Aurelie; Thompson, Leslie M.; Andreakos, Evangelos; Zhang, Qian; Anderson, Mark S.; Casanova, Jean-Laurent; DeRisi, Joseph L.

Aurélie Cobat

个人简介

教育背景

工作经历

荣誉奖项

研究方向