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Behdad Afzali

national institute of diabetes and digestive and kidney diseases
H指数:48
被引数:8,400

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A PI3Kd-Foxo1-FasL signaling amplification loop rewires CD4+T helper cell signaling, differentiation and epigenetic remodeling
JOURNAL OF IMMUNOLOGY
IF3.4
2025-11-010
PRE
Golec, Dominic P.; Gazzinelli-Guimaraes, Pedro; Chauss, Daniel; Nagashima, Hiroyuki; Yu, Kang; Hill, Tom; Cannons, Jennifer L.; Perry, Jillian; Joshi, Ilin; Pereira, Nicolas; Silva Oliveira, Fabricio Marcus; Cruz, Anthony C.; Druey, Kirk M.; Lack, Justin B.; Nutman, Thomas B.; Villarino, Alejandro V.; O'Shea, John J.; Afzali, Behdad; Schwartzberg, Pamela L.
Cell-autonomous complement C3 activity in prostate epithelial cells suppresses malignant transformation through tonic restrain of the MYC-tumorigenesis program
JOURNAL OF IMMUNOLOGY
IF3.4
2025-11-010
PRE
Kunz, Natalia; Bibby, Jack A.; Merle, Nicolas S.; Kartal, Sumeyra; Yamamoto, Hidekazu; Wang, Luopin; Taj, Md; Ma, Jianping; Kolev, Martin, V; Lotscher, Jonas; Kellerhals, Tamara; Balmer, Maria L.; Chandra, Ash; Hess, Christoph; Afzali, Behdad; Dasgupta, Prokar; West, Erin E.; Sowalsky, Adam G.; Kemper, Claudia
A foundation model for human-AI collaboration in medical literature mining

一个用于医学文献挖掘中的人机协作的基础模型

Nature Communications
IF15.7
2025-09-240
OAAI
Zifeng Wang; Lang Cao; Qiao Jin; Joey Chan; Nicholas Wan; Behdad Afzali; Hyun-Jin Cho; Chang-In Choi; Mehdi Emamverdi; Manjot K. Gill; Sun-Hyung Kim; Yijia Li; Yi Liu; Yiming Luo; Hanley Ong; Justin F. Rousseau; Irfan Sheikh; Jenny J. Wei; Ziyang Xu; Christopher M. Zallek; Kyungsang Kim; Yifan Peng; Zhiyong Lu; Jimeng Sun
A CD4+ T cell-intrinsic complement C5aR2-prostacyclin-IL-1R2 axis orchestrates Th1 cell contraction

CD4+ T细胞内源性补体C5aR2-前列环素-IL-1R2轴调控Th1细胞的收缩

Immunity
IF26.3
2025-05-300
OA
Jubayer Rahman; Jack A. Bibby; Parul Singh; Nicolas S. Merle; Erin E. West; Andrea Bohrer; Katrin Mayer-Barber; Chengyu Liu; Lauren R. Brinster; Behdad Afzali; Ana M. Briones; Sara Alehashemi; Farzana Bhuyan; Jiahui Ge; Xijian Chen; Yingbi Zhou; Murray C.H. Clarke; Bin Liu; Raphaela Goldbach-Mansky; C. Henrique Serezani; Claudia Kemper
A deep intronic splice-altering AIRE variant causes APECED syndrome through antisense oligonucleotide-targetable pseudoexon inclusion
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2024-09-181
PRE
Ochoa, Sebastian; Hsu, Amy P.; Oler, Andrew J.; Kumar, Dhaneshwar; Chauss, Daniel; van Hamburg, Jan Piet; van Laar, Gustaaf G.; Oikonomou, Vasileios; Ganesan, Sundar; Ferre, Elise M. N.; Schmitt, Monica M.; Dimaggio, Tom; Barber, Princess; Constantine, Gregory M.; Rosen, Lindsey B.; Auwaerter, Paul G.; Gandhi, Bhumika; Miller, Jennifer L.; Eisenberg, Rachel; Rubinstein, Arye; Schussler, Edith; Balliu, Erjola; Shashi, Vandana; Neth, Olaf; Olbrich, Peter; Le, Kim My; Mamia, Nanni; Laakso, Saila; Nevalainen, Pasi I.; Groenholm, Juha; Seppaenen, Mikko R. J.; Boon, Louis; Uzel, Gulbu; Franco, Luis M.; Heller, Theo; Winer, Karen K.; Ghosh, Rajarshi; Seifert, Bryce A.; Walkiewicz, Magdalena; Notarangelo, Luigi D.; Zhou, Qing; Askentijevich, Ivona; Gahl, William; Dalgard, Cliffton L.; Perera, Lalith; Afzali, Behdad; Tas, Sander W.; Holland, Steven M.; Lionakis, Michail S.
Unbiased discovery of cancer pathways and therapeutics using Pathway Ensemble Tool and Benchmark

使用通路集成工具和基准无偏见地发现癌症通路和治疗方法

NATURE COMMUNICATIONS
IF15.7
2024-08-240
OAAI
Wang, Luopin; Pattnaik, Aryamav; Sahoo, Subhransu Sekhar; Stone, Ella G.; Zhuang, Yuxin; Benton, Annaleigh; Tajmul, Md; Chakravorty, Srishti; Dhawan, Deepika; Nguyen, My An; Sirit, Isabella; Mundy, Kyle; Ricketts, Christopher J.; Hadisurya, Marco; Baral, Garima; Tinsley, Samantha L.; Anderson, Nicole L.; Hoda, Smriti; Briggs, Scott D.; Kaimakliotis, Hristos Z.; Allen-Petersen, Brittany L.; Tao, W. Andy; Linehan, W. Marston; Knapp, Deborah W.; Hanna, Jason A.; Olson, Matthew R.; Afzali, Behdad; Kazemian, Majid
Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection

CD4 T细胞的损失-内在精氨酸酶1加速Th1反应动力学并减少流感感染期间的肺部病理

IMMUNITY
IF26.3
2023-09-0117
OAAI
West, Erin E.; Merle, Nicolas S.; Kaminski, Marcin M.; Palacios, Gustavo; Kumar, Dhaneshwar; Wang, Luopin; Bibby, Jack A.; Overdahl, Kirsten; Jarmusch, Alan K.; Freeley, Simon; Lee, Duck-Yeon; Thompson, J. Will; Yu, Zu-Xi; Taylor, Naomi; Sitbon, Marc; Green, Douglas R.; Bohrer, Andrea; Mayer-Barber, Katrin D.; Afzali, Behdad; Kazemian, Majid; Scholl-Buergi, Sabine; Karall, Daniela; Huemer, Martina; Kemper, Claudia
Successful Treatment of Paecilomyces variotii Pneumonia and Lupus Nephritis With Posaconazole-Cyclophosphamide Co-administration Without Drug Interaction-Induced Toxicity
OPEN FORUM INFECTIOUS DISEASES
IF3.8
2023-08-020
OA
Pechacek, Joseph; Webb, Taura; Ferre, Elise M. N.; Schmitt, Monica M.; DiMaggio, Thomas; Kobrin, Dale; Rajasimhan, Suraj; Colton, Ben; Lewis, Russell E.; Andes, David; Herrera, Alejandro; Hammoud, Dima; Seyedmousavi, Seyedmojtaba; Hasni, Sarfaraz; Bolanos, Jonathan; Afzali, Behdad; Lionakis, Michail S.
Transcription factor EGR2 controls homing and pathogenicity of TH17 cells in the central nervous system

转录因子EGR2控制中枢神经系统TH17细胞的归巢和致病性

NATURE IMMUNOLOGY
IF27.6
2023-07-131
OA
Gao, Yuanyuan; Wang, Yan; Chauss, Daniel; Villarino, Alejandro V.; Link, Verena M.; Nagashima, Hiroyuki; Spinner, Camille A.; Koparde, Vishal N.; Bouladoux, Nicolas; Abers, Michael S.; Break, Timothy J.; Chopp, Laura B.; Park, Jung-Hyun; Zhu, Jinfang; Wiest, David L.; Leonard, Warren J.; Lionakis, Michail S.; O'Shea, John J.; Afzali, Behdad; Belkaid, Yasmine; Lazarevic, Vanja
A comprehensive single cell data analysis of lymphoblastoid cells reveals the role of super-enhancers in maintaining EBV latency
JOURNAL OF MEDICAL VIROLOGY
IF4.6
2022-12-135
OAAI
Yan, Bingyu; Wang, Chong; Chakravorty, Srishti; Zhang, Zonghao; Kadadi, Simran D.; Zhuang, Yuxin; Sirit, Isabella; Hu, Yonghua; Jung, Minwoo; Sahoo, Subhransu S.; Wang, Luopin; Shao, Kunming; Anderson, Nicole L.; Trujillo-Ochoa, Jorge L.; Briggs, Scott D.; Liu, Xing; Olson, Matthew R.; Afzali, Behdad; Zhao, Bo; Kazemian, Majid

研究方向

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M
Majid Kazemian
H 指数:33论文数:146被引数:3,345
C
Claudia Kemper
H 指数:58论文数:300被引数:1.2万
D
Daniel Chauss
H 指数:20论文数:92被引数:2,324
G
Giovanna Lombardi
H 指数:79论文数:376被引数:2.0万
L
Luopin Wang
H 指数:17论文数:76被引数:1,183
E
Erin E. West
H 指数:36论文数:112被引数:7,199
M
Michail S. Lionakis
H 指数:77论文数:500被引数:2.3万
J
John J. O’Shea
H 指数:131论文数:477被引数:7.3万
M
Martin Kolev
H 指数:22论文数:75被引数:3,800
S
Susan John
H 指数:36论文数:90被引数:6,240