David G. Schatz - Publications, H-index & Citations

David G. Schatz

Yale School of Medicine

71H指数

328论文数

2.1W被引数

收录论文 111

发表时间

Transcription pause and elongation regulators mediate somatic hypermutation 转录暂停和延伸调节因子介导体细胞高频突变

Nature

IF48.5

2026-09-30

OAAI

Lizhen Wu; Anurupa Devi Yadavalli; Caillan C. McAuliffe; Qi Ha; Mahsa Nouri Barkestani; Foad Rommasi; Isaac Fianu; Filip Senigl; David G. Schatz

A 3D genome atlas of human tonsil and the role of loop extrusion in B cell somatic hypermutation 人类扁桃体的三维基因组图谱及环外推在B细胞体细胞超突变中的作用

Science

IF45.8

2026-07-23

PREAI

Yubao Cheng; Jianshu Wang; Yuan Zhang; Anurupa Devi Yadavalli; Miao Liu; Shengyan Jin; Grace Buddle; Ann Haberman; David G. Schatz; Siyuan Wang

Structural and evolutionary divergence of the RAG1/1L N-terminal zinc-coordinating domain RAG1/1L N端锌配位结构域的结构与进化分歧

Cell Reports

IF6.9

2026-07-01

PREAI

Hong, Junye; Liu, Zhijun; Xu, Wei; Martin, Eliza C.; Wei, Kunyu; Schatz, David G.; Zhang, Yuhang

Author Correction: Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia 作者更正：儿童急性淋巴细胞白血病的克隆进化机制

Nature Immunology

IF27.6

2025-11-28

PREAI

Srividya Swaminathan; Lars Klemm; Eugene Park; Elli Papaemmanuil; Anthony Ford; Soo-Mi Kweon; Daniel Trageser; Brian Hasselfeld; Nadine Henke; Jana Mooster; Huimin Geng; Klaus Schwarz; Scott C. Kogan; Rafael Casellas; David G. Schatz; Michael R. Lieber; Mel F. Greaves; Markus Müschen

Transcription elongation factor ELOF1 is required for efficient somatic hypermutation and class switch recombination 转录延伸因子ELOF1对于高效的体细胞超突变和类别转换重组是必需的。

MOLECULAR CELL

IF16.6

2025-04-01

OAAI

Wu, Lizhen; Yadavalli, Anurupa Devi; Senigl, Filip; Matos-Rodrigues, Gabriel; Xu, Dijin; Pintado-Urbanc, Andreas P.; Simon, Matthew D.; Wu, Wei; Nussenzweig, Andre; Schatz, David G.

RORγt up-regulates RAG gene expression in DP thymocytes to expand the Tcra repertoire

SCIENCE IMMUNOLOGY

IF16.3

2024-03-15

OAAI

Naik, Abani Kanta; Dauphars, Danielle J.; Corbett, Elizabeth; Simpson, Lunden; Schatz, David G.; Krangel, Michael S.

Insights into RAG Evolution from the Identification of Missing Link Family A RAGL Transposons

MOLECULAR BIOLOGY AND EVOLUTION

IF5.3

2023-10-18

OAAI

Martin, Eliza C.; Le Targa, Lorlane; Tsakou-Ngouafo, Louis; Fan, Tzu-Pei; Lin, Che-Yi; Xiao, Jianxiong; Huang, Ziwen; Yuan, Shaochun; Xu, Anlong; Su, Yi-Hsien; Petrescu, Andrei-Jose; Pontarotti, Pierre; Schatz, David G.

Dancing with DNA: AID embraces flexible partners

CELL RESEARCH

IF25.9

2023-05-12

OAAI

Wang, Jianshu; Schatz, David G.

A basic motif in the N-terminal region of RAG1 enhances V(D)J recombination activity

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-29

OAAI

McMahan, CJ; Difilippantonio, MJ; Rao, N; Spanopoulou, E; Schatz, DG

Fluorescence resonance energy transfer analysis of recombination signal sequence configuration in the RAG1/2 synaptic complex

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Ciubotaru, Mihai; Kriatchko, Aleksei N.; Swanson, Patrick C.; Bright, Frank V.; Schatz, David G.

Synapsis of recombination signal sequences located in cis and DNA underwinding in V(D)J recombination

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Ciubotaru, M; Schatz, DG

The beyond 12/23 restriction is imposed at the nicking and pairing steps of DNA cleavage during V(D)J recombination

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Drejer-Teel, Anna H.; Fugmann, Sebastian D.; Schatz, David G.

Mobilization of RAG-generated signal ends by transposition and insertion in vivo

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Chatterji, M; Tsai, CL; Schatz, DG

Recruitment of RAG1 and RAG2 to Chromatinized DNA during V(D)J Recombination

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

OAAI

Shetty, Keerthi; Schatz, David G.

Synapsis Alters RAG-Mediated Nicking at Tcrb Recombination Signal Sequences: Implications for the Beyond 12/23 Rule

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

OAAI

Banerjee, Joydeep K.; Schatz, David G.

Ig Enhancers Increase RNA Polymerase II Stalling at Somatic Hypermutation Target Sequences

JOURNAL OF IMMUNOLOGY

IF3.4

2022-01-01

OAAI

Tarsalainen, Alina; Maman, Yaakov; Meng, Fei-Long; Kylaniemi, Minna K.; Soikkeli, Anni; Budzynska, Paulina; McDonald, Jessica J.; Senigl, Filip; Alt, Frederic W.; Schatz, David G.; Alinikula, Jukka

Structural insights into the evolution of the RAG recombinase

NATURE REVIEWS IMMUNOLOGY

IF60.9

2021-10-21

PREAI

Liu, Chang; Zhang, Yuhang; Liu, Catherine C.; Schatz, David G.

RAG2 abolishes RAG1 aggregation to facilitate V(D)J recombination

CELL REPORTS

IF6.9

2021-10-01

OAAI

Gan, Tingting; Wang, Yuhong; Liu, Yang; Schatz, David G.; Hu, Jiazhi

The RAG1 N-terminal region regulates the efficiency and pathways of synapsis for V(D)J recombination

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2021-08-17

OAAI

Beilinson, Helen A.; Glynn, Rebecca A.; Yadavalli, Anurupa Devi; Xiao, Jianxiong; Corbett, Elizabeth; Saribasak, Huseyin; Arya, Rahul; Miot, Charline; Bhattacharyya, Anamika; Jones, Jessica M.; Pongubala, Jagan M. R.; Bassing, Craig H.; Schatz, David G.

Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) activity is required for V(D)J recombination

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2021-05-25

OAAI

Chen, Chun-Chin; Chen, Bo-Ruei; Wang, Yinan; Curman, Philip; Beilinson, Helen A.; Brecht, Ryan M.; Liu, Catherine C.; Farrell, Ryan J.; de Juan-Sanz, Jaime; Charbonnier, Louis-Marie; Kajimura, Shingo; Ryan, Timothy A.; Schatz, David G.; Chatila, Talal A.; Wikstrom, Jakob D.; Tyler, Jessica K.; Sleckman, Barry P.

研究方向