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Ó

Óscar Llorca

structural biology programme

52H指数
186论文数
7.7K被引数
收录论文 108
发表时间
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CONCR lncRNA organizes a 3′-end structural domain that engages DDX11 for DNA replication and sister chromatid cohesionCONCR长链非编码RNA组织一个3′端结构域，该结构域与DDX11相互作用以参与DNA复制和姐妹染色单体凝聚
errMolecular Cell
IF16.6
err2026-08-28
err0
errOAAI
errAndrés López-Perrote; Eva María Martín-Cuevas; José Antonio Mérida-Cerro; Clara Aicart-Ramos; Ana González-Corpas; Jovanna González; Johanne Le Coq; Jasminka Boskovic; Isabel Chillón; Oscar Llorca; Fernando Moreno-Herrero; Maite Huarte
err分享
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OT-Curtains: an approach for studying protein interactions with DNA ends using optical tweezers and confocal fluorescence microscopyOT-窗帘：一种利用光镊和共聚焦荧光显微镜研究蛋白质与DNA末端相互作用的方法
errNucleic Acids Research
IF13.1
err2026-05-08
err0
PREAI
errDe Braganca, Sara; Aicart-Ramos, Clara; Rivera-Calzada, Angel; Arribas-Bosacoma, Raquel; Dillingham, Mark S.; Llorca, Oscar; Moreno-Herrero, Fernando
err分享
err收藏
Structural basis of human γTuRC closure during CM1-activated microtubule nucleation人γTuRC在CM1激活的微管成核过程中的结构基础
errNature Communications
IF15.7
err2026-03-26
err0
errOAAI
errMarina Serna; Cláudia Brito; Silvia Speroni; Fabian Zimmermann; Andrés Lopez-Perrote; Maria Gili; Cristina Lacasa; Jens Lüders; Thomas Surrey; Oscar Llorca
err分享
err收藏
Automated and modular protein binder design with BinderFlow
errPLOS COMPUTATIONAL BIOLOGY
IF3.6
err2025-11-01
err0
PREAI
errGonzalez-Rodriguez, Nayim; Chacon-Sanchez, Carlos; Llorca, Oscar; Fernandez-Leiro, Rafael
err分享
err收藏
Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activityWAC与R2TP和TTT分子伴侣复合物的相互作用表征，将葡萄糖和谷氨酰胺的可利用性与mTORC1活性联系起来
errFEBS Open Bio
IF2.3
err2025-07-13
err0
errOAAI
errSofía Cabezudo; Natalia Cuervo; Carmen García-Martín; Andrés López-Perrote; Clara Reglero; Adrián Maqueda-Real; Ana González-Corpas; Marina Serna; Diego Megías; Alejo Efeyan; Solip Park; Oscar Llorca
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The structure of the R2T complex reveals a different architecture from the related HSP90 cochaperone R2TP (vol 33, pg 740, 2025)R2T复合物的结构揭示了一种与相关HSP90共分子伴侣R2TP不同的架构（卷33，页740，2025）。
errSTRUCTURE
IF4.3
err2025-05-01
err0
PREAI
errPalacios-Abella, Alberto; Lopez-Perrote, Andres; Boskovic, Jasminka; Fonseca, Sandra; Urbez, Cristina; Rubio, Vicente; Llorca, Oscar; Alabadi, David
err分享
err收藏
Article The structure of the R2T complex reveals a different architecture from the related HSP90 cochaperone R2TP文章：R2T复合物的结构揭示了一种与相关HSP90共分子伴侣R2TP不同的架构。
errSTRUCTURE
IF4.3
err2025-02-01
err1
PREAI
errPalacios-Abella, Alberto; Lopez-Perrote, Andres; Boskovic, Jasminka; Fonseca, Sandra; Urbez, Cristina; Rubio, Vicente; Llorca, Oscar; Alabadi, David
err分享
err收藏
The conserved lysine residue in transmembrane helix 5 is pivotal for the cytoplasmic gating of the L-amino acid transporters
errPNAS NEXUS
IF3.8
err2025-01-02
err0
errOAAI
errFort, Joana; Nicolas-Arago, Adria; Maggi, Luca; Martinez-Molledo, Maria; Kapiki, Despoina; Gonzalez-Novoa, Paula; Gomez-Gejo, Patricia; Zijlstra, Niels; Bodoy, Susanna; Pardon, Els; Steyaert, Jan; Llorca, Oscar; Orozco, Modesto; Cordes, Thorben; Palacin, Manuel
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CDK5RAP2 activates microtubule nucleator γTuRC by facilitating template formation and actin release
errDEVELOPMENTAL CELL
IF8.7
err2024-12-01
err1
PREAI
errSerna, Marina; Zimmermann, Fabian; Vineethakumari, Chithran; Gonzalez-Rodriguez, Nayim; Llorca, Oscar; Luders, Jens
err分享
err收藏
SETD8 inhibition targets cancer cells with increased rates of ribosome biogenesisSETD8抑制靶向核糖体生物发生速率增加的癌细胞
errCELL DEATH & DISEASE
IF9.6
err2024-09-28
err0
errOAAI
errMurga, Matilde; Lopez-Pernas, Gema; Soliva, Robert; Fueyo-Marcos, Elena; Amor, Corina; Faustino, Ignacio; Serna, Marina; Serrano, Alicia G.; Diaz, Lucia; Martinez, Sonia; Blanco-Aparicio, Carmen; Anton, Marta Elena; Seashore-Ludlow, Brinton; Pastor, Joaquin; Jafari, Rozbeh; Lafarga, Miguel; Llorca, Oscar; Orozco, Modesto; Fernandez-Capetillo, Oscar
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err收藏
Mechanism of allosteric inhibition by the small molecule CB-6644
errCELL REPORTS PHYSICAL SCIENCE
IF7.3
err2024-06-01
err0
errOAAI
errGarcia-Martin, Carmen; Lopez-Perrote, Andres; Boskovic, Jasminka; Llorca, Oscar
err分享
err收藏
Structure and mechanisms of transport of human Asc1/CD98hc amino acid transporter人源Asc1/CD98hc氨基酸转运蛋白的结构与转运机制
errNATURE COMMUNICATIONS
IF15.7
err2024-04-06
err1
errOAAI
errRullo-Tubau, Josep; Martinez-Molledo, Maria; Bartoccioni, Paola; Puch-Giner, Ignasi; Arias, Angela; Saen-Oon, Suwipa; Stephan-Otto Attolini, Camille; Artuch, Rafael; Diaz, Lucia; Guallar, Victor; Errasti-Murugarren, Ekaitz; Palacin, Manuel; Llorca, Oscar
err分享
err收藏
BICD2 phosphorylation regulates dynein function and centrosome separation in G2 and M
errNATURE COMMUNICATIONS
IF15.7
err2023-04-27
err6
errOAAI
errGallisa-Sune, Nuria; Sanchez-Fernandez-de-Landa, Paula; Zimmermann, Fabian; Serna, Marina; Regue, Laura; Paz, Joel; Llorca, Oscar; Luders, Jens; Roig, Joan
err分享
err收藏
Molecular architecture and oligomerization of Candida glabrata Cdc13 underpin its telomeric DNA-binding and unfolding activity
errNUCLEIC ACIDS RESEARCH
IF13.1
err2023-01-11
err0
errOAAI
errColoma, Javier; Gonzalez-Rodriguez, Nayim; Balaguer, Francisco A.; Gmurczyk, Karolina; Aicart-Ramos, Clara; Nuero, oscar M.; Luque-Ortega, Juan Roman; Calugaru, Kimberly; Lue, Neal F.; Moreno-Herrero, Fernando; Llorca, Oscar
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err收藏
APLF and long non-coding RNA NIHCOLE promote stable DNA synapsis in non-homologous end joining
errCELL REPORTS
IF6.9
err2023-01-01
err9
errOAAI
errDe Braganc, Sara; Aicart-Ramos, Clara; Arribas-Bosacoma, Raquel; Rivera-Calzada, Angel; Unfried, Juan Pablo; Prats-Mari, Laura; Marin-Baquero, Mikel; Fortes, Puri; Llorca, Oscar; Moreno-Herrero, Fernando
err分享
err收藏
Structural basis for the inactivation of cytosolic DNA sensing by the vaccinia virus
errNATURE COMMUNICATIONS
IF15.7
err2022-11-18
err8
errOAAI
errRivera-Calzada, Angel; Arribas-Bosacoma, Raquel; Ruiz-Ramos, Alba; Escudero-Bravo, Paloma; Boskovic, Jasminka; Fernandez-Leiro, Rafael; Oliver, Antony W.; Pearl, Laurence H.; Llorca, Oscar
err分享
err收藏
HATs meet structural biology
errCURRENT OPINION IN STRUCTURAL BIOLOGY
IF7
err2022-06-01
err2
PREAI
errRullo-Tubau, Josep; Bartoccioni, Paola; Llorca, Oscar; Errasti-Murugarren, Ekaitz; Palacin, Manuel
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CryoEM of RUVBL1-RUVBL2-ZNHIT2, a complex that interacts with pre-mRNA-processing-splicing factor 8
errNUCLEIC ACIDS RESEARCH
IF13.1
err2021-12-24
err8
errOAAI
errSerna, Marina; Gonzalez-Corpas, Ana; Cabezudo, Sofia; Lopez-Perrote, Andres; Degliesposti, Gianluca; Zarzuela, Eduardo; Mark Skehel, J.; Munoz, Javier; Llorca, Oscar
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err收藏
Structural basis for substrate specificity of heteromeric transporters of neutral amino acids
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2021-11-30
err13
errOAAI
errRodriguez, Carlos F.; Escudero-Bravo, Paloma; Diaz, Lucia; Bartoccioni, Paola; Garcia-Martin, Carmen; Gilabert, Joan G.; Boskovic, Jasminka; Guallar, Victor; Errasti-Murugarren, Ekaitz; Llorca, Oscar; Palacin, Manuel
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err收藏
The Bacterial Mucosal Immunotherapy MV130 Protects Against SARS-CoV-2 Infection and Improves COVID-19 Vaccines Immunogenicity
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2021-11-18
err27
errOAAI
errdel Fresno, Carlos; Garcia-Arriaza, Juan; Martinez-Cano, Sarai; Heras-Murillo, Ignacio; Jarit-Cabanillas, Aitor; Amores-Iniesta, Joaquin; Brandi, Paola; Dunphy, Gillian; Suay-Corredera, Carmen; Pricolo, Maria Rosaria; Vicente, Natalia; Lopez-Perrote, Andres; Cabezudo, Sofia; Gonzalez-Corpas, Ana; Llorca, Oscar; Alegre-Cebollada, Jorge; Garaigorta, Urtzi; Gastaminza, Pablo; Esteban, Mariano; Sancho, David
err分享
err收藏

研究方向

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