未登录 Pancreatic beta-cell IL-22 receptor deficiency induces age-dependent dysregulation of insulin biosynthesis and systemic glucose homeostasis Sajiir, Haressh; Wong, Kuan Yau; Mueller, Alexandra; Keshvari, Sahar; Burr, Lucy; Aiello, Elena; Mezza, Teresa; Giaccari, Andrea; Sebastiani, Guido; Dotta, Francesco; Ramm, Grant A.; Macdonald, Graeme A.; McGuckin, Michael A.; Prins, Johannes B.; Hasnain, Sumaira Z. 分享 收藏
Liver and pancreatic-targeted interleukin-22 as a therapeutic for metabolic dysfunction-associated steatohepatitis Sajiir, Haressh; Keshvari, Sahar; Wong, Kuan Yau; Borg, Danielle J.; Steyn, Frederik J.; Fercher, Christian; Taylor, Karin; Taylor, Breten; Barnard, Ross T.; Mueller, Alexandra; Moniruzzaman, Md; Miller, Gregory; Wang, Ran; Fotheringham, Amelia; Schreiber, Veronika; Sheng, Yong Hua; Hancock, Janelle Louise; Loo, Dorothy; Burr, Lucy; Huynh, Tony; Lockett, Jack; Ramm, Grant A.; Macdonald, Graeme A.; Prins, Johannes B.; Mcguckin, Michael A.; Hasnain, Sumaira Z. 分享 收藏
Interleukin-22 suppresses major histocompatibility complex II in mucosal epithelial cells Moniruzzaman, Md; Rahman, M. Arifur; Wang, Ran; Wong, Kuan Yau; Chen, Alice C. -H.; Mueller, Alexandra; Taylor, Steven; Harding, Alexa; Illankoon, Thishan; Wiid, Percival; Sajiir, Haressh; Schreiber, Veronika; Burr, Lucy D.; Mcguckin, Michael A.; Phipps, Simon; Hasnain, Sumaira Z. 分享 收藏
MUC13 Cell Surface Mucin Limits Salmonella Typhimurium Infection by Protecting the Mucosal Epithelial Barrier McGuckin, Michael A.; Davies, Julie M.; Felgner, Pascal; Wong, Kuan Yau; Giri, Rabina; He, Yaowu; Moniruzzaman, Md; Kryza, Thomas; Sajiir, Haressh; Hooper, John D.; Florin, Timothy H.; Begun, Jakob; Oussalah, Abderrahim; Hasnain, Sumaira Z.; Hensel, Michael; Sheng, Yong H. 分享 收藏
Pancreatic Interleukin-22 Receptor Signaling is Critical in Maintaining Beta-Cell Insulin Production and is Hepatoprotective Sajiir, Haressh; Wong, Kuan Yau; Mueller, Alexandra; Keshvari, Sahar; Wang, Ran; Wiid, Percival; Macdonald, Graeme; Prins, John; McGuckin, Michael A.; Hasnain, Sumaira Z. 分享 收藏
Secreted NF-κB suppressive microbial metabolites modulate gut inflammation 分泌的nf-κb抑制性微生物代谢产物调节肠道炎症 Giri, Rabina; Hoedt, Emily C.; Khushi, Shamsunnahar; Salim, Angela A.; Bergot, Anne-Sophie; Schreiber, Veronika; Thomas, Ranjeny; McGuckin, Michael A.; Florin, Timothy H.; Morrison, Mark; Capon, Robert J.; Cuiv, Paraic O.; Begun, Jakob 分享 收藏
MUC1-mediated Macrophage Activation Promotes Colitis-associated Colorectal Cancer via Activating the Interleukin-6/Signal Transducer and Activator of Transcription 3 Axis MUC1-mediated巨噬细胞激活通过激活Interleukin-6/信号转导和转录激活因子3轴促进结肠炎相关结直肠癌 Sheng, Yong H.; Davies, Julie M.; Wang, Ran; Wong, Kuan Yau; Giri, Rabina; Yang, Yuanhao; Begun, Jakob; Florin, Timothy H.; Hasnain, Sumaira Z.; McGuckin, Michael A. 分享 收藏
Drug repurposing: Misconceptions, challenges, and opportunities for academic researchers 药物再利用: 学术研究人员的误解，挑战和机遇 Begley, C. Glenn; Ashton, Mark; Baell, Jonathan; Bettess, Michael; Brown, Michael P.; Carter, Brett; Charman, William N.; Davis, Christopher; Fisher, Simon; Frazer, Ian; Gautam, Anand; Jennings, Michael P.; Kearney, Philip; Keeffe, Eloise; Kelly, Darren; Lopez, Angel F.; McGuckin, Michael; Parker, Michael W.; Rayner, Craig; Roberts, Brett; Rush, James S.; Sullivan, Mark 分享 收藏
pH - Responsive colloidal carriers assembled from β-lactoglobulin and Epsilon poly-L-lysine for oral drug delivery 由 β-乳球蛋白和 ε-聚-L-赖氨酸组装而成的pH响应性胶体载体，用于口服药物输送 Pujara, Naisarg; Giri, Rabina; Wong, Kuan Yau; Qu, Zhi; Rewatkar, Prarthana; Moniruzzaman, Md.; Begun, Jakob; Ross, Benjamin P.; McGuckin, Michael; Popat, Amirali 分享 收藏
Gut microbiota shape the inflammatory response in mice with an epithelial defect 肠道菌群塑造具有上皮缺陷的小鼠的炎症反应 Wang, Ran; Moniruzzaman, Md; Wong, Kuan Yau; Wiid, Percival; Harding, Alexa; Giri, Rabina; Tong, Wendy (Hui); Creagh, Jackie; Begun, Jakob; McGuckin, Michael A.; Hasnain, Sumaira Z. 分享 收藏
A Nucleotide Analog Prevents Colitis-Associated Cancer via Beta-Catenin Independently of Inflammation and Autophagy 核苷酸类似物通过 β-连环蛋白独立于炎症和自噬来预防结肠炎相关的癌症 Sheng, Yong Hua; Giri, Rabina; Davies, Julie; Schreiber, Veronika; Alabbas, Saleh; Movva, Ramya; He, Yaowu; Wu, Andy; Hooper, John; McWhinney, Brett; Oancea, Iulia; Kijanka, Gregor; Hasnain, Sumaira; Lucke, Andrew J.; Fairlie, David P.; McGuckin, Michael A.; Florin, Timothy H.; Begun, Jakob 分享 收藏
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Airway Mucus Hyperconcentration in Non-Cystic Fibrosis Bronchiectasis 非囊性纤维化支气管扩张中的气道粘液高浓度 Ramsey, Kathryn A.; Chen, Alice C. H.; Radicioni, Giorgia; Lourie, Rohan; Martin, Megan; Broomfield, Amy; Sheng, Yong H.; Hasnain, Sumaira Z.; Radford-Smith, Graham; Simms, Lisa A.; Burr, Lucy; Thornton, David J.; Bowler, Simon D.; Livengood, Stephanie; Ceppe, Agathe; Knowles, Michael R.; Noone, Peadar G., Sr.; Donaldson, Scott H.; Hill, David B.; Ehre, Camille; Button, Brian; Alexis, Neil E.; Kesimer, Mehmet; Boucher, Richard C.; McGuckin, Michael A. 分享 收藏
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CDCP1 enhances Wnt signaling in colorectal cancer promoting nuclear localization of β-catenin and E-cadherin CDCP1增强结直肠癌Wnt信号通路促进 β-catenin和e-cadherin的核定位 He, Yaowu; Davies, Claire M.; Harrington, Brittney S.; Hellmers, Linh; Sheng, Yonghua; Broomfield, Amy; McGann, Thomas; Bastick, Kate; Zhong, Laurie; Wu, Andy; Maresh, Grace; McChesney, Shannon; Wong, Kuan Yau; Adams, Mark N.; Sullivan, Ryan C.; Palmer, James S.; Burke, Lez J.; Ewing, Adam D.; Zhang, Xin; Margolin, David; Li, Li; Lourie, Rohan; Matsika, Admire; Srinivasan, Bhuvana; McGuckin, Michael A.; Lumley, John W.; Hooper, John D. 分享 收藏
MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity MUC13通过 β-catenin活性促进结肠炎相关结直肠肿瘤的发展 Sheng, Yong Hua; Wong, Kuan Yau; Seim, Inge; Wang, Ran; He, Yaowu; Wu, Andy; Patrick, Maya; Lourie, Rohan; Schreiber, Veronika; Giri, Rabina; Ng, Choa Ping; Popat, Amirali; Hooper, John; Kijanka, Gregor; Florin, Timothy H.; Begun, Jakob; Radford, Kristen J.; Hasnain, Sumaira; McGuckin, Michael A. 分享 收藏
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Expression of CD69 on peripheral lymphocytes predicts treatment response in Acute Severe ulcerative colitis Choy, M. C.; Yu, J.; Congiu, M.; Pelpola, P.; Nigro, J.; Burder, R.; Boyd, K.; McGuckin, M.; Corbett, A. J.; Kjer-Nielsen, L.; McCluskey, J.; Visvanathan, K.; De Cruz, P. 分享 收藏
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