Staffan G. Svärd - Publications, H-index & Citations

Staffan G. Svärd

uppsala university

54H指数

227论文数

9.6K被引数

收录论文 68

发表时间

Host range expansion of asexual parasite can be explained by loss of adaptions in Muller’s Ratchet 无性寄生虫的寄主范围扩大可以通过Muller棘轮的适应性丧失来解释。

Nature Communications

IF15.7

2025-12-01

OAAI

Swapnil Tichkule; Cock van Oosterhout; Simone M. Cacciò; Filip Weisz; Balu Balan; Eva Nohýnková; Myo Naung; Brendan R. E. Ansell; Samantha J. Emery-Corbin; Louise Baker; Marco Lalle; Staffan Svärd; Robin B. Gasser; Aaron R. Jex

The expanded genome of Hexamita inflata, a free-living diplomonad 扩展的六前滴虫 (Hexamita inflata) 基因组，一种自由生活的双滴虫目生物

SCIENTIFIC DATA

IF6.9

2025-02-01

OAAI

Akdeniz, Zeynep; Havelka, Michal; Stoklasa, Michal; Jimenez-Gonzalez, Alejandro; Zarsky, Vojtech; Xu, Feifei; Stairs, Courtney W.; Jerlstroem-Hultqvist, Jon; Kolisko, Martin; Provaznik, Jan; Svaerd, Staffan; Andersson, Jan O.; Tachezy, Jan

Tetramerization of deoxyadenosine kinase meets the demands of a DNA replication substrate challenge in Giardia intestinalis

NUCLEIC ACIDS RESEARCH

IF13.1

2024-11-28

OAAI

Ranjbarian, Farahnaz; Rafie, Karim; Shankar, Kasturika; Krakovka, Sascha; Svard, Staffan G.; Carlson, Lars-Anders; Hofer, Anders

Adaptation of the late ISC pathway in the anaerobic mitochondrial organelles of Giardia intestinalis

PLOS PATHOGENS

IF4.9

2023-10-04

OAAI

Motyckova, Alzbeta; Voleman, Lubos; Najdrova, Vladimira; Arbonova, Lenka; Benda, Martin; Dohnalek, Vit; Janowicz, Natalia; Malych, Ronald; Sutak, Robert; Ettema, Thijs J. G.; Svard, Staffan; Stairs, Courtney W.; Dolezal, Pavel

Transcriptomic analysis of albendazole resistance in human diarrheal parasite Giardia duodenalis 人类腹泻寄生虫十二指肠贾第鞭毛虫对阿苯达唑耐药性的转录组学分析

INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE

IF3.4

2023-08-01

OAAI

Su, Qiao; Baker, Louise; Emery, Samantha; Balan, Balu; Ansell, Brendan; Tichkule, Swapnil; Mueller, Ivo; Svard, Staffan G.; Jex, Aaron

Trophozoite fitness dictates the intestinal epithelial cell response to Giardia intestinalis infection 滋养体适应性决定了肠上皮细胞对贾第虫感染的反应

PLOS PATHOGENS

IF4.9

2023-05-04

OAAI

Gruttner, Jana; van Rijn, Jorik M.; Geiser, Petra; Florbrant, Alexandra; Webb, Dominic-Luc; Hellstrom, Per M.; Sundbom, Magnus; Sellin, Mikael E.; Svard, Staffan G.

Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis

NUCLEIC ACIDS RESEARCH

IF13.1

2023-03-13

OAAI

Majumdar, Soneya; Emmerich, Andrew; Krakovka, Sascha; Mandava, Chandra Sekhar; Svard, Staffan G.; Sanyal, Suparna

Comprehensive characterization of Cysteine-rich protein-coding genes of Giardia lamblia and their role during antigenic variation

GENOMICS

IF3

2022-09-01

OAAI

Rodriguez-Walker, Macarena; Molina, Cecilia R.; Lujan, Lucas A.; Saura, Alicia; Jerlstrom-Hultqvist, Jon; Svard, Staffan G.; Fernandez, Elmer A.; Lujan, Hugo D.

Giardia duodenalis

Trends in Parasitology

IF6.6

2022-07-01

OAAI

Rojas-Lopez, Laura; Marques, Rafael C.; Svard, Staffan G.

Giardia intestinalis thymidine kinase is a high-affinity enzyme crucial for DNA synthesis and an exploitable target for drug discovery

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-06-01

OAAI

Krakovka, Sascha; Ranjbarian, Farahnaz; Lujan, Lucas A.; Saura, Alicia; Larsen, Nicolai B.; Jimenez-Gonzalez, Alejandro; Reggenti, Anna; Lujan, Hugo D.; Svard, Staffan G.; Hofer, Anders

Ivermectin-induced gene expression changes in adult Parascaris univalens and Caenorhabditis elegans: a comparative approach to study anthelminthic metabolism and resistance in vitro

PARASITES & VECTORS

IF3.5

2022-05-05

OAAI

Dube, Faruk; Hinas, Andrea; Roy, Shweta; Martin, Frida; Abrink, Magnus; Svard, Staffan; Tyden, Eva

High-Definition DIC Imaging Uncovers Transient Stages of Pathogen Infection Cycles on the Surface of Human Adult Stem Cell-Derived Intestinal Epithelium 高清DIC成像揭示了成人干细胞衍生的肠上皮表面上病原体感染周期的短暂阶段

MBIO

IF4.7

2022-02-22

OAAI

van Rijn, Jorik M.; Eriksson, Jens; Gruttner, Jana; Sundbom, Magnus; Webb, Dominic-Luc; Hellstrom, Per M.; Svard, Staffan G.; Sellin, Mikael E.

Characterization of Metronidazole-Resistant Giardia intestinalis Lines by Comparative Transcriptomics and Proteomics

FRONTIERS IN MICROBIOLOGY

IF4.5

2022-02-10

OAAI

Krakovka, Sascha; Ribacke, Ulf; Miyamoto, Yukiko; Eckmann, Lars; Svard, Staffan

Dual RNA-seq transcriptome analysis of caecal tissue during primary Eimeria tenella infection in chickens 鸡原代艾美耳球虫感染盲肠组织的双重rna-seq转录组分析

BMC GENOMICS

IF3.7

2021-09-14

OAAI

Sandholt, Arnar K. S.; Wattrang, Eva; Lilja, Tobias; Ahola, Harri; Lunden, Anna; Troell, Karin; Svard, Staffan G.; Soderlund, Robert

Multimodal regulation of encystation in Giardia duodenalis revealed by deep proteomics 深层蛋白质组学揭示十二指肠贾第鞭毛虫包裹的多模态调控

INTERNATIONAL JOURNAL FOR PARASITOLOGY

IF3.2

2021-09-01

OAAI

Balan, Balu; Emery-Corbin, Samantha J.; Sandow, Jarrod J.; Ansell, Brendan Robert E.; Tichkule, Swapnil; Webb, Andrew, I; Svard, Staffan G.; Jex, Aaron R.

Serglycin-Deficiency Causes Reduced Weight Gain and Changed Intestinal Cytokine Responses in Mice Infected With Giardia intestinalis

FRONTIERS IN IMMUNOLOGY

IF5.9

2021-07-08

OAAI

Li, Zhiqiang; Peirasmaki, Dimitra; Svard, Staffan; Abrink, Magnus

Eukaryote-conserved histone post-translational modification landscape in Giardia duodenalis revealed by mass spectrometry

INTERNATIONAL JOURNAL FOR PARASITOLOGY

IF3.2

2021-03-01

PREAI

Emery-Corbin, Samantha J.; Hamey, Joshua J.; Balan, Balu; Rojas-Lopez, Laura; Svard, Staffan G.; Jex, Aaron R.

The compact genome of Giardia muris reveals important steps in the evolution of intestinal protozoan parasites

MICROBIAL GENOMICS

IF4

2020-08-01

OAAI

Xu, Feifei; Jimenez-Gonzalez, Alejandro; Einarsson, Elin; Astvaldsson, Asgeir; Peirasmaki, Dimitra; Eckmann, Lars; Andersson, Jan O.; Svard, Staffan G.; Jerlstrom-Hultqvist, Jon

Eukaryote-ConservedMethylarginine Is Absent in Diplomonads and Functionally Compensated in Giardia

MOLECULAR BIOLOGY AND EVOLUTION

IF5.3

2020-07-23

OAAI

Emery-Corbin, Samantha J.; Hamey, Joshua J.; Ansell, Brendan R. E.; Balan, Balu; Tichkule, Swapnil; Stroehlein, Andreas J.; Cooper, Crystal; McInerney, Bernie, V; Hediyeh-Zadeh, Soroor; Vuong, Daniel; Crombie, Andrew; Lacey, Ernest; Davis, Melissa J.; Wilkins, Marc R.; Bahlo, Melanie; Svard, Staffan G.; Gasser, Robin B.; Jex, Aaron R.

The Chymase Mouse Mast Cell Protease-4 Regulates Intestinal Cytokine Expression in Mature Adult Mice Infected with Giardia intestinalis

CELLS

IF5.2

2020-04-09

OAAI

Li, Zhiqiang; Peirasmaki, Dimitra; Svaerd, Staffan; Abrink, Magnus

研究方向