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D

Devon J. Shedlock

inc
H指数:31
被引数:4,741

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TSCM-predominant allogeneic anti-BCMA CAR-T therapy for relapsed/refractory multiple myeloma: preclinical characterization and interim results from a phase 1 trial

TSCM优势的异基因抗BCMA CAR-T疗法治疗复发/难治性多发性骨髓瘤：临床前表征和1期试验的初步结果

Nature Communications
IF15.7
2025-11-240
OAAI
Hubert Tseng; Bhagirathbhai Dholaria; Stacey A. Cranert; Maximilian Richter; Karl S. Marquez; Benjamin S. Cho; Andrew Bacong; Katherine McArthur; Jeff D. Eskew; Joanne McCaigue; Sabrina Haag; Aly Krasny; Brian Solimine; Michael J. Coffey; Aimee Loyola; Jasmine Kwong; Leyla Shune; Andrew Kin; Caitlin L. Costello; Mehmet H. Kocoglu; Aravind Ramakrishnan; Hamid Namini; Christopher E. Martin; Rajesh Belani; Julia Coronella; Devon J. Shedlock
Solid tumor patients require higher cyclophosphamide (cy) dose than multiple myeloma (MM) patients to achieve adequate lymphodepletion (LD) necessary to enable allogeneic CAR-T expansion
CANCER RESEARCH
IF16.6
2024-04-050
PRE
Haag, Sabrina; Eskew, Jeff D.; McArthur, Katherine; McCaigue, Joanne; Vaziri, Sepideh; DePrimo, Samuel; Martin, Christopher E.; Gregovics, Catherine; Murphy, Ann; Namini, Hamid; Christie, Ellen; Marinez-Prieto, Marcela; Belani, Rajesh; Cranert, Stacey; Coronella, Julia; Shedlock, Devon
Clinical activity of P-BCMA-ALLO1, a B-cell maturation antigen (BCMA) targeted allogeneic chimeric antigen receptor T-cell (CAR-T) therapy, in relapsed refractory multiple myeloma (RRMM) patients (pts) following progression on prior BCMA targeting therapy
CANCER RESEARCH
IF16.6
2024-04-052
PRE
Dholaria, Bhagirathbhai; Shune, Leyla; Kin, Andrew; McArthur, Katherine; Eskew, Jeff D.; Martin, Christopher E.; Haag, Sabrina; McCaigue, Joanne; Namini, Hamid; DePrimo, Sam; Cranert, Stacey; Coronella, Julia; Shedlock, Devon; Belani, Rajesh
Cas-CLOVER is a novel high-fidelity nuclease for safe and robust generation of TSCM-enriched allogeneic CAR-T cells

Cas-三叶草是一种新型的高保真核酸酶，用于安全和稳健地生成富含TSCM的同种异体car-t细胞

MOLECULAR THERAPY-NUCLEIC ACIDS
IF0
2022-09-0131
OAAI
Madison, Blair B.; Patil, Deepak; Richter, Maximilian; Li, Xianghong; Tong, Min; Cranert, Stacey; Wang, Xinxin; Martin, Renata; Xi, Haibin; Tan, Yening; Weiss, Leslie; Marquez, Karl; Coronella, Julia; Shedlock, Devon J.; Ostertag, Eric M.
Cas-CLOVER is a novel high-fidelity nuclease for safe and robust generation of TSCM-enriched allogeneic CAR-T cells

Cas-CLOVER是一种新型高保真核酸酶，可用于安全、高效地制备富含记忆干细胞样T细胞的同种异体CAR-T细胞。

MOLECULAR THERAPY-NUCLEIC ACIDS
IF0
2022-09-010
OAAI
Madison, Blair B.; Patil, Deepak; Richter, Maximilian; Li, Xianghong; Tong, Min; Cranert, Stacey; Wang, Xinxin; Martin, Renata; Xi, Haibin; Tan, Yening; Weiss, Leslie; Marquez, Karl; Coronella, Julia; Shedlock, Devon J.; Ostertag, Eric M.
Protective Efficacy and Long-Term Immunogenicity in Cynomolgus Macaques by Ebola Virus Glycoprotein Synthetic DNA Vaccines
JOURNAL OF INFECTIOUS DISEASES
IF4.5
2018-10-1032
OAAI
Patel, Ami; Reuschel, Emma L.; Kraynyak, Kimberly A.; Racine, Trina; Park, Daniel H.; Scott, Veronica L.; Audet, Jonathan; Amante, Dinah; Wise, Megan C.; Keaton, Amelia A.; Wong, Gary; Villarreal, Daniel O.; Walters, Jewell; Muthumani, Kar; Shedlock, Devon J.; de La Vega, Marc-Antoine; Plyler, Ross; Boyer, Jean; Broderick, Kate E.; Yan, Jian; Khan, Amir S.; Jones, Shane; Bello, Alexander; Soule, Geoff; Tran, Kaylie N.; He, Shihua; Tierney, Kevin; Qiu, Xiangguo; Kobinger, Gary P.; Sardesai, Niranjan Y.; Weiner, David B.
A Single Immunization With Optimized DNA Vaccines Protects Against Lethal Ebola Virus Challenge in Mice and Induces Seroconversion in Non-Human Primates Following a DNA Prime-DNA Boost Approach
MOLECULAR THERAPY
IF12
2015-05-010
OAAI
Patel, Ami; Reuschel, Emma L.; Scott, Veronica L.; Kraynyak, Kimberly A.; Wong, Gary; Villarreal, Daniel O.; Karuppiah, Muthumani; Shedlock, Devon; Yan, Jian; Broderick, Kate E.; Khan, Amir; Tierney, Kevin; Kobinger, Gary P.; Sardesai, Niranjan; Weiner, David B.
A DNA Vaccine against Chikungunya Virus Is Protective in Mice and Induces Neutralizing Antibodies in Mice and Nonhuman Primates
PLOS NEGLECTED TROPICAL DISEASES
IF3.4
2011-01-11166
OAAI
Mallilankaraman, Karthik; Shedlock, Devon J.; Bao, Huihui; Kawalekar, Omkar U.; Fagone, Paolo; Ramanathan, Aarthi A.; Ferraro, Bernadette; Stabenow, Jennifer; Vijayachari, Paluru; Sundaram, Senthil G.; Muruganandam, Nagarajan; Sarangan, Gopalsamy; Srikanth, Padma; Khan, Amir S.; Lewis, Mark G.; Kim, J. Joseph; Sardesai, Niranjan Y.; Muthumani, Karuppiah; Weiner, David B.

研究方向

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D
David B. Weiner
H 指数:92论文数:805被引数:3.2万
M
Muthumani, Karuppiah
H 指数:0论文数:14被引数:2
A
Amir Sada Khan
H 指数:54论文数:285被引数:9,623
S
Stacey Cranert
H 指数:11论文数:32被引数:555
J
Julia Coronella
H 指数:13论文数:50被引数:925
N
Niranjan Y. Sardesai
H 指数:47论文数:208被引数:7,273
E
Eric Ostertag
H 指数:27论文数:78被引数:4,842
J
Jian Yan
H 指数:44论文数:206被引数:6,616
O
Omkar U. Kawalekar
H 指数:14论文数:38被引数:6,307
D
Daniel O. Villarreal
H 指数:17论文数:82被引数:1,197