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IL10 gene mutations do not impair Tr1 differentiation in vivo and can be functionally corrected by precise gene editing Strubbe, Steven; Boss, Allison; Wang, Bing; Mantilla, Michelle Mercedes; Freeborn, Robert Arthur; Guevara Becerra, Martha; Gharahdaghi, Nima; Uhlig, Holm H.; Porteus, Matthew Hebden; Arkwright, Peter D.; Roncarolo, Maria-Grazia; Bacchetta, Rosa 分享 收藏
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Immune-epithelial-stromal networks define the cellular ecosystem of the small intestine in celiac disease 免疫-上皮-间质网络定义了乳糜泻中小肠的细胞生态系统。 FitzPatrick, Michael E. B.; Antanaviciute, Agne; Dunstan, Melanie; Kunnapuu, Karolina; Trzupek, Dominik; Provine, Nicholas M.; Dooley, Kyla; Zhang, Jia-Yuan; Irwin, Sophie L.; Garner, Lucy C.; Pernes, Jane I.; Ferreira, Ricardo C.; Sasson, Sarah C.; Aschenbrenner, Dominik; Agarwal, Devika; Rodrigues, Astor; Howarth, Lucy; Brain, Oliver; Ruane, Darren; Soilleux, Elizabeth; Teichmann, Sarah A.; Dendrou, Calliope A.; Simmons, Alison; Uhlig, Holm H.; Todd, John A.; Klenerman, Paul 分享 收藏
Altered chaperone-nonmuscle myosin II interactions drive pathogenicity of the UNC45A c.710T>C variant in osteo-oto-hepato-enteric syndrome 改变的热休克蛋白-非肌球蛋白II相互作用驱动UNC45A c.710T>C变异在骨-耳-肝-肠综合征中的致病性 Waich, Stephanie; Kreidl, Karin; Vodopiutz, Julia; Demir, Arzu Meltem; Pollio, Adam R.; Dostal, Vojtech; Pfaller, Kristian; Parlato, Marianna; Cerf-Bensussan, Nadine; Adam, Ruediger; Vogel, Georg F.; Uhlig, Holm H.; Ruemmele, Frank M.; Mueller, Thomas; Hess, Michael W.; Janecke, Andreas R.; Huber, Lukas A.; Valovka, Taras 分享 收藏
Upadacitinib for Induction of Remission in Paediatric Crohn's Disease: An International Multicentre Retrospective Study 乌帕替尼用于诱导儿童克罗恩病缓解：一项国际多中心回顾性研究 Cohen, S; Spencer, EA; Dolinger, MT; Suskind, DL; Mitrova, K; Hradsky, O; Conrad, MA; Kelsen, JR; Uhlig, HH; Tzivinikos, C; Henderson, P; Wlazlo, M; Hackl, L; Shouval, DS; Bramuzzo, M; Urlep, D; Olbjorn, C; D'Arcangelo, G; Pujol-Muncunill, G; Yogev, D; Kang, B; Gasparetto, M; Rungoe, C; Kolho, KL; Hojsak, I; Norsa, L; Rinawi, F; Sansotta, N; Rimon, RM; Granot, M; Scarallo, L; Trindade, E; Rodríguez-Belvís, MV; Turner, D; Yerushalmy-Feler, A 分享 收藏
Upadacitinib for induction of remission in pediatric Crohn's disease: An international multicenter study Yerushalmy-Feler, A.; Spencer, E. A.; Dolinger, M. T.; Suskind, D. L.; Mitrova, K.; Hradsky, O.; Conrad, M. A.; Kelsen, J. R.; Uhlig, H. H.; Tzivinikos, C.; Henderson, P.; Wlazlo, M.; Hackl, L.; Shouval, D. S.; Bramuzzo, M.; Urlep, D.; Olbjorn, C.; D'Arcangelo, G.; Pujol-Muncunill, G.; Yogev, D.; Kang, B.; Gasparetto, M.; Rungoe, C.; Kolho, K. L.; Hojsak, I; Norsa, L.; Rinawi, F.; Sansotta, N.; Rimon, R. Magen; Granot, M.; Scarallo, L.; Trindade, E.; Rodriguez-Belvis, M. Velasco; Turner, D.; Cohen, S. 分享 收藏
Upadacitinib for induction of remission in pediatric Ulcerative Colitis: An international multicenter study Yerushalmy-Feler, A.; Spencer, E. A.; Dolinger, M. T.; Suskind, D. L.; Mitrova, K.; Hradsky, O.; Conrad, M. A.; Kelsen, J. R.; Uhlig, H. H.; Tzivinikos, C.; Ancona, S.; Wlazlo, M.; Hackl, L.; Shouval, D. S.; Bramuzzo, M.; Urlep, D.; Olbjorn, C.; D'Arcangelo, G.; Pujol-Muncunill, G.; Yogev, D.; Kang, B.; Gasparetto, M.; Rungo, C.; Kolho, K. L.; Hojsak, I; Norsa, L.; Rinawi, F.; Sansotta, N.; Rimon, R. Magen; Granot, M.; Scarallo, L.; Trindade, E.; Rodriguez-Belvis, M. Velasco; Turner, D.; Cohen, S. 分享 收藏
Colonic goblet cell dysfunction and gastric intestinal metaplasia in patients with anterior gradient 2 defects and infantile Inflammatory bowel disease Azabdaftari, A.; Al-Shaibi, A.; Thomas, T.; Jainarayanan, A.; Capitani, M.; Verleur, N.; Agarwal, D.; Dooley, K.; Rich-Griffin, C.; Provine, N.; Klenerman, P.; Elawad, M.; Travis, S.; Buckley, C.; Dendrou, C.; Lo, B.; Uhlig, H. 分享 收藏
Upadacitinib for Induction of Remission in Pediatric Ulcerative Colitis: An International Multicenter Study Upadacitinib诱导小儿溃疡性结肠炎缓解: 一项国际多中心研究 Yerushalmy-Feler, Anat; Spencer, Elizabeth A.; Dolinger, Michael T.; Suskind, David L.; Mitrova, Katarina; Hradsky, Ondrej; Conrad, Maire A.; Kelsen, Judith R.; Uhlig, Holm H.; Tzivinikos, Christos; Ancona, Silvana; Wlazlo, Magdalena; Hackl, Lukas; Shouval, Dror S.; Bramuzzo, Matteo; Urlep, Darja; Olbjorn, Christine; D'Arcangelo, Giulia; Pujol-Muncunill, Gemma; Yogev, Dotan; Kang, Ben; Gasparetto, Marco; Rungo, Christine; Kolho, Kaija-Leena; Hojsak, Iva; Norsa, Lorenzo; Rinawi, Firas; Sansotta, Naire; Magen Rimon, Ramit; Granot, Maya; Scarallo, Luca; Trindade, Eunice; Velasco Rodriguez-Belvis, Marta; Turner, Dan; Cohen, Shlomi 分享 收藏
A longitudinal single-cell atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease 炎症性肠病中抗肿瘤坏死因子治疗的纵向单细胞图谱 Thomas, Tom; Friedrich, Matthias; Rich-Griffin, Charlotte; Pohin, Mathilde; Agarwal, Devika; Pakpoor, Julia; Lee, Carl; Tandon, Ruchi; Rendek, Aniko; Aschenbrenner, Dominik; Jainarayanan, Ashwin; Voda, Alexandru; Siu, Jacqueline H. Y.; Sanches-Peres, Raphael; Nee, Eloise; Sathananthan, Dharshan; Kotliar, Dylan; Todd, Peter; Kiourlappou, Maria; Gartner, Lisa; Ilott, Nicholas; Issa, Fadi; Hester, Joanna; Turner, Jason; Nayar, Saba; Mackerodt, Jonas; Zhang, Fan; Jonsson, Anna; Brenner, Michael; Raychaudhuri, Soumya; Kulicke, Ruth; Ramsdell, Danielle; Stransky, Nicolas; Pagliarini, Ray; Bielecki, Piotr; Spies, Noah; Marsden, Brian; Taylor, Stephen; Wagner, Allon; Klenerman, Paul; Walsh, Alissa; Coles, Mark; Jostins-Dean, Luke; Powrie, Fiona M.; Filer, Andrew; Travis, Simon; Uhlig, Holm H.; Dendrou, Calliope A.; Buckley, Christopher D. 分享 收藏
The Circulating Methylome in Childhood-Onset Inflammatory Bowel Disease Noble, Alexandra; Adams, Alex; Nowak, Jan; Cheng, Guo; Nayak, Komal; Quinn, Aisling; Kristiansen, Mark; Kalla, Rahul; Ventham, Nicholas T.; Giachero, Federica; Jayamanne, Chamara; Hansen, Richard; Hold, Georgina L.; El-Omar, Emad; Croft, Nicholas M.; Wilson, David; Beattie, R. Mark; Ashton, James J.; Zilbauer, Matthias; Ennis, Sarah; Uhlig, Holm H.; Satsangi, Jack 分享 收藏
Biallelic PI4KA Mutations Disrupt B-Cell Metabolism and Cause B-Cell Lymphopenia and Hypogammaglobulinemia 双等位基因PI4KA突变破坏b细胞代谢并导致b细胞淋巴细胞减少和低丙种球蛋白血症 Saettini, Francesco; Guerra, Fabiola; Mauri, Mario; Salter, Claire G.; Adam, Margaret P.; Adams, David; Baple, Emma L.; Barredo, Estibaliz; Bhatia, Sanil; Borkhardt, Arndt; Brusco, Alfredo; Bugarin, Cristina; Chinello, Clizia; Crosby, Andrew H.; D'Souza, Precilla; Denti, Vanna; Fazio, Grazia; Giuliani, Silvia; Kuehn, Hye Sun; Amel, Hassan; Elmi, Asha; Lo, Bernice; Malighetti, Federica; Mandrile, Giorgia; Martin-Nalda, Andrea; Mefford, Heather C.; Moratto, Daniele; Mousavi, Fatemeh Emam; Nelson, Zoe; Gutierrez-Solana, Luis Gonzalez; Macnamara, Ellen; Michaud, Vincent; O'Leary, Melanie; Pagani, Lisa; Pavinato, Lisa; Santamaria, Patricia VVelez; Planas-Serra, Laura; Quadri, Manuel; Raspall-Chaure, Miquel; Rebellato, Stefano; Rosenzweig, Sergio D.; Roubertie, Agathe; Holzinger, Dirk; Deal, Christin; Vockley, Catherine Walsh; Savino, Angela Maria; Stoddard, Jennifer L.; Uhlig, Holm H.; Pujol, Aurora; Magni, Fulvio; Paglia, Giuseppe; Cazzaniga, Gianni; Piazza, Rocco; Barberis, Matteo; Biondi, Andrea 分享 收藏
Successful Allogeneic Hematopoietic Cell Transplantation for Patients with IL10RA Deficiency in Japan Tomomasa, Dan; Suzuki, Tasuku; Takeuchi, Ichiro; Goto, Kimitoshi; Hagiwara, Shin-Ichiro; Keino, Dai; Saida, Satoshi; Ishige, Takashi; Kudo, Takahiro; Eguchi, Katsuhide; Ishimura, Masataka; Matsuda, Yusuke; Wada, Taizo; Ito, Yoshiya; Kato, Motohiro; Sasahara, Yoji; Morio, Tomohiro; Arai, Katsuhiro; Uhlig, Holm H.; Kanegane, Hirokazu 分享 收藏
Neutralizing Autoantibodies against Interleukin-10 in Inflammatory Bowel Disease Griffin, Helen; Ceron-Gutierrez, Lourdes; Gharahdaghi, Nima; Ebrahimi, Soraya; Davies, Sophie; Loo, Peh Sun; Szabo, Andras; Williams, Eleri; Mukhopadhyay, Anirban; Mcloughlin, Louise; Irwin, Steven; Travis, Simon; Klenerman, Paul; Bunn, Su; Cant, Andrew J.; Hambleton, Sophie; Uhlig, Holm H.; Doffinger, Rainer 分享 收藏
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