S
Sung-Yun Pai
H指数:55
被引数:1.2万
个人简介
Dr. Sung-Yun Pai received her M.D. degree from Harvard Medical School where she worked in the laboratory of Dr. Barbara Bierer on the cellular biology of calcineurin and mechanism of action of cyclosporine, tacrolimus, and sirolimus. She trained in pediatrics at Boston Children’s Hospital and pediatric hematology-oncology at Boston Children’s Hospital and Dana-Farber Cancer Institute. There she performed post-doctoral work in the laboratories of Drs. Jeffrey Leiden, I-Cheng Ho, and Laurie Glimcher demonstrating the critical roles of the transcription factor GATA3 in thymocyte development, T helper 2 cell specification and function, as well as in CD8 T cells, invariant NK-T cells, and collaboratively in breast cancer and keratinocyte development. As faculty she specialized in clinical hematopoietic stem cell transplantation for children with inborn errors of immunity and led a research program focused on development, implementation, and analysis of clinical trials of transplantation and gene therapy for these disorders. She was appointed to Associate Professor at Harvard Medical School in 2016 and served as Associate Director then Co-Director of the Gene Therapy Program at Boston Children’s Hospital. In 2020, she moved to the National Cancer Institute and National Institute of Allergy and Infectious Diseases to assume the role of Chief of the Immune Deficiency Cellular Therapy Program. Key areas of focus include severe combined immunodeficiency, Wiskott-Aldrich syndrome, and DOCK8 deficiency.
教育背景
暂无内容
工作经历
2020.01 – 至今
National Cancer Institute
Chief of the Immune Deficiency Cellular Therapy Program
荣誉奖项
暂无内容
免疫监测和表型评估对临床轨迹的影响(IMPACT),用于原发性免疫缺陷治疗联盟(PIDTC)中免疫先天性错误疾病患者
病毒特异性T细胞和HCT治疗后PML的缓解
免疫缺陷病中的隐孢子虫病:一项单中心队列研究及文献综述
Wiskott-Aldrich综合征携带者的临床谱:193名携带者的自我报告调查
Clinical Immunology
IF5.7
脐带血移植为缺乏HLA匹配供体的慢性肉芽肿病患者提供了替代方案:一份PIDTC报告
聚合酶链式反应(PCR)在异基因造血细胞移植后弓形虫病诊断与管理中的有效性与局限性:单中心16年经验,涉及31例患者
造血干细胞移植后免疫恢复期间人体皮肤微生物组的恢复
Cell Host & Microbe
IF18.7
异基因造血干细胞移植治疗STAT3高IgE综合征:一项全球性研究
Blood Advances
IF7.1
如何治疗Wiskott-Aldrich综合征
Blood
IF23.1
感染相关免疫重建炎症综合征在造血细胞移植中的应用
BLOOD ADVANCES
IF7.1
NATURE COMMUNICATIONS
IF15.7
NATURE COMMUNICATIONS
IF15.7
BLOOD ADVANCES
IF7.1
LANCET
IF88.5

