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Thomas J. Simpson

university of bristol

52H指数
346论文数
9.7K被引数
收录论文 70
发表时间
Mutasynthesis and Antibiotic Activity of Mupirocin Analogues通过突变合成法制备的莫匹罗星类似物的抗生菌活性
err2026-06-30
err0
errOAAI
errSarah M. Husain; Luoyi Wang; Li-Chen Han; James I. Bowen; Zhongshu Song; Felix de Courcy-Ireland; Ashley J. Winter; Thomas J. Simpson; Paul R. Race; James Spencer; Matthew P. Crump; Christine L. Willis
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VpROM: a novel variational autoencoder-boosted reduced order model for the treatment of parametric dependencies in nonlinear systems
err2024-03-13
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errOAAI
errSimpson, Thomas; Vlachas, Konstantinos; Garland, Anthony; Dervilis, Nikolaos; Chatzi, Eleni
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Naturally Occurring Partially Reduced Perylenequinones from Fungi
err2022-09-13
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PREAI
errGeris, Regina; Pinho, Matheus A.; Boffo, Elisangela F.; Simpson, Thomas J.
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Cladobotric Acids: Metabolites from Cultures of Cladobotryum sp., Semisynthetic Analogues and Antibacterial Activity
err2022-02-16
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errOAAI
errDao, Trong-Tuan; Williams, Katherine; de Mattos-Shipley, Kate M. J.; Song, Zhongshu; Takebayashi, Yuiko; Simpson, Thomas J.; Spencer, James; Bailey, Andrew M.; Willis, Christine L.
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Total Synthesis of Kalimantacin A
err2020-08-10
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errOAAI
errDavies, Jonathan A.; Bull, Freya M.; Walker, Paul D.; Weir, Angus N. M.; Lavigne, Rob; Masschelein, Joleen; Simpson, Thomas J.; Race, Paul R.; Crump, Matthew P.; Willis, Christine L.
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The Kalimantacin Polyketide Antibiotics Inhibit Fatty Acid Biosynthesis in Staphylococcus aureus by Targeting the Enoyl-Acyl Carrier Protein Binding Site of FabI
err2020-04-14
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errOAAI
errFage, Christopher D.; Lathouwers, Thomas; Vanmeert, Michiel; Gao, Ling-Jie; Vrancken, Kristof; Lammens, Eveline-Marie; Weir, Angus N. M.; Degroote, Ruben; Cuppens, Harry; Kosol, Simone; Simpson, Thomas J.; Crump, Matthew P.; Willis, Christine L.; Herdewijn, Piet; Lescrinier, Eveline; Lavigne, Rob; Anne, Jozef; Masschelein, Joleen
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A Priming Cassette Generates Hydroxylated Acyl Starter Units in Mupirocin and Thiomarinol Biosynthesis
err2020-01-24
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errOAAI
errWalker, Paul D.; Rowe, Matthew T.; Winter, Ashley J.; Weir, Angus N. M.; Akter, Nahida; Wang, Luoyi; Race, Paul R.; Williams, Christopher; Song, Zhongshu; Simpson, Thomas J.; Willis, Christine L.; Crump, Matthew P.
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Mixing and matching genes of marine and terrestrial origin in the biosynthesis of the mupirocin antibiotics
err2020-01-01
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errOAAI
errWang, Luoyi; Song, Zhongshu; Race, Paul R.; Spencer, James; Simpson, Thomas J.; Crump, Matthew P.; Willis, Christine L.
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Uncovering biosynthetic relationships between antifungal nonadrides and octadrides
err2020-01-01
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errOAAI
errde Mattos-Shipley, Kate M. J.; Spencer, Catherine E.; Greco, Claudio; Heard, David M.; O'Flynn, Daniel E.; Dao, Trong T.; Song, Zhongshu; Mulholland, Nicholas P.; Vincent, Jason L.; Simpson, Thomas J.; Cox, Russell J.; Bailey, Andrew M.; Willis, Christine L.
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Control of β-Branching in Kalimantacin Biosynthesis: Application of 13C NMR to Polyketide Programming
err2019-08-07
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PREAI
errWalker, Paul D.; Williams, Christopher; Weir, Angus N. M.; Wang, Luoyi; Crosby, John; Race, Paul R.; Simpson, Thomas J.; Willis, Christine L.; Crump, Matthew P.
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Defining the genes for the final steps in biosynthesis of the complex polyketide antibiotic mupirocin by Pseudomonas fluorescens NCIMB10586
err2019-02-07
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errOAAI
errConnolly, Jack A.; Wilson, Amber; Macioszek, Malgorzata; Song, Zhongshu; Wang, Luoyi; Mohammad, Hadi H.; Yadav, Mukul; di Martino, Maura; Miller, Claire E.; Hothersall, Joanne; Haines, Anthony S.; Stephens, Elton R.; Crump, Matthew P.; Willis, Christine L.; Simpson, Thomas J.; Winn, Peter J.; Thomas, Christopher M.
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Obituary: James (Jim) Ralph Hanson (1937-2018)
err2019-01-01
err0
PREAI
errSmith, J. David; Simpson, Thomas J.; Willis, Christine L.
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Characterisation of the biosynthetic pathway to agnestins A and B reveals the reductive route to chrysophanol in fungi
err2019-01-01
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errOAAI
errSzwalbe, Agnieszka J.; Williams, Katherine; Song, Zhongshu; de Mattos-Shipley, Kate; Vincent, Jason L.; Bailey, Andrew M.; Willis, Christine L.; Cox, Russell J.; Simpson, Thomas J.
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Molecular basis of methylation and chain-length programming in a fungal iterative highly reducing polyketide synthase
err2019-01-01
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errOAAI
errYang, Xiao-Long; Friedrich, Steffen; Yin, Sen; Piech, Oliver; Williams, Katherine; Simpson, Thomas J.; Cox, Russell J.
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Structure revision of cryptosporioptides and determination of the genetic basis for dimeric xanthone biosynthesis in fungi
err2019-01-01
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errOAAI
errGreco, Claudio; de Mattos-Shipley, Kate; Bailey, Andrew M.; Mulholland, Nicholas P.; Vincent, Jason L.; Willis, Christine L.; Cox, Russell J.; Simpson, Thomas J.
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Strobilurin biosynthesis in Basidiomycete fungi
err2018-09-26
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errOAAI
errNofiani, Risa; de Mattos-Shipley, Kate; Lebe, Karen E.; Han, Li-Chen; Iqbal, Zafar; Bailey, Andrew M.; Willis, Christine L.; Simpson, Thomas J.; Cox, Russell J.
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The cycloaspeptides: uncovering a new model for methylated nonribosomal peptide biosynthesis
err2018-01-01
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errde Mattos-Shipley, Kate M. J.; Greco, Claudio; Heard, David M.; Hough, Gemma; Mulholland, Nicholas P.; Vincent, Jason L.; Micklefield, Jason; Simpson, Thomas J.; Willis, Christine L.; Cox, Russell J.; Bailey, Andrew M.
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Selected Mutations Reveal New Intermediates in the Biosynthesis of Mupirocin and the Thiomarinol Antibiotics
err2017-02-09
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errGao, Shu-Shan; Wang, Luoyi; Song, Zhongshu; Hothersall, Joanne; Stevens, Elton R.; Connolly, Jack; Winn, Peter J.; Cox, Russell J.; Crump, Matthew P.; Race, Paul R.; Thomas, Christopher M.; Simpson, Thomas J.; Willis, Christine L.
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