Susan L. Swain - Publications, H-index & Citations

Susan L. Swain

university of massachusetts system

88H指数

312论文数

2.8W被引数

收录论文 120

发表时间

CD4 memory has a hierarchical structure created by requirements for infection-derived signals at an effector checkpoint CD4记忆具有由效应器检查点的感染衍生信号的要求创建的分层结构

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-12-12

OAAI

Swain, Susan L.

Cytotoxic CD4 development requires CD4 effectors to concurrently recognize local antigen and encounter type I IFN-induced IL-15 (vol 42, 113182, 2023)

CELL REPORTS

IF6.9

2023-11-01

OAAI

Devarajan, Priyadharshini; Vong, Allen M.; Castonguay, Catherine H.; Silverstein, Noah J.; Kugler-Umana, Olivia; Bautista, Bianca L.; Kelly, Karen A.; Luban, Jeremy; Swain, Susan L.

Cytotoxic CD4 development requires CD4 effectors to concurrently recognize local antigen and encounter type I IFN-induced IL-15

CELL REPORTS

IF6.9

2023-10-01

OAAI

Devarajan, Priyadharshini; Vong, Allen M.; Castonguay, Catherine H.; Silverstein, Noah J.; Kugler-Umana, Olivia; Bautista, Bianca L.; Kelly, Karen A.; Luban, Jeremy; Swain, Susan L.

CD4 Effector TCR Avidity for Peptide on APC Determines the Level of Memory Generated CD4效应子TCR对APC上肽的亲和力决定了产生的记忆水平

JOURNAL OF IMMUNOLOGY

IF3.4

2023-04-24

OAAI

Jones, Michael C.; Castonguay, Catherine; Nanaware, Padma P.; Weaver, Grant C.; Stadinski, Brian; Kugler-Umana, Olivia A.; Huseby, Eric S.; Stern, Lawrence J.; McKinstry, Karl Kai; Strutt, Tara M.; Devarajan, Priyadharshini; Swain, Susan L.

IgD+ age-associated B cells are the progenitors of the main T-independent B cell response to infection that generates protective Ab and can be induced by an inactivated vaccine in the aged 与年龄相关的IgD b细胞是主要的T非依赖性b细胞对感染的反应的祖细胞，可产生保护性Ab，并可由老年人的灭活疫苗诱导。

AGING CELL

IF7.1

2022-09-02

OAAI

Kugler-Umana, Olivia; Zhang, Wenliang; Kuang, Yi; Liang, Jialing; Castonguay, Catherine H.; Tonkonogy, Susan L.; Marshak-Rothstein, Ann; Devarajan, Priyadharshini; Swain, Susan L.

Bona Fide Th17 Cells without Th1 Functional Plasticity Protect against Influenza

JOURNAL OF IMMUNOLOGY

IF3.4

2022-04-15

OAAI

Dhume, Kunal; Finn, Caroline M.; Devarajan, Priyadharshini; Singh, Ayushi; Tejero, Joanne D.; Prokop, Emily; Strutt, Tara M.; Sell, Stewart; Swain, Susan L.; McKinstry, Karl Kai

Strong influenza-induced TFH generation requires CD4 effectors to recognize antigen locally and receive signals from continuing infection

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-02-17

OAAI

Devarajan, Priyadharshini; Vong, Allen M.; Castonguay, Catherine H.; Kugler-Umana, Olivia; Bautista, Bianca L.; Jones, Michael C.; Kelly, Karen A.; Xia, Jingya; Swain, Susan L.

An Intrinsic Program Determines Key Age-Associated Changes in Adaptive Immunity That Limit Response to Non-Pathogens

FRONTIERS IN AGING

IF4.3

2021-06-24

OAAI

Swain, Susan L.; Kugler-Umana, Olivia; Tonkonogy, Susan L.

Durable CD4 T-Cell Memory Generation Depends on Persistence of High Levels of Infection at an Effector Checkpoint that Determines Multiple Fates

cold spring harbor perspectives in medicine

IF8.4

2021-04-26

OAAI

Swain, Susan L.; Jones, Michael C.; Devarajan, Priyadharshini; Xia, Jingya; Dutton, Richard W.; Strutt, Tara M.; McKinstry, K. Kai

CD25-Targeted IL-2 Signals Promote Improved Outcomes of Influenza Infection and Boost Memory CD4 T Cell Formation

JOURNAL OF IMMUNOLOGY

IF3.4

2020-06-15

OAAI

Alam, Fahmida; Singh, Ayushi; Flores-Malavet, Valeria; Sell, Stewart; Cooper, Andrea M.; Swain, Susan L.; McKinstry, K. Kai; Strutt, Tara M.

Memory CD4 T cell-derived IL-2 synergizes with viral infection to exacerbate lung inflammation

PLOS PATHOGENS

IF4.9

2019-08-14

OAAI

McKinstry, K. Kai; Alam, Fahmida; Flores-Malavet, Valeria; Nagy, Mate Z.; Sell, Stewart; Cooper, Andrea M.; Swain, Susan L.; Strutt, Tara M.

IL-15 supports the generation of protective lung-resident memory CD4 T cells

MUCOSAL IMMUNOLOGY

IF7.6

2018-05-01

OAAI

Strutt, T. M.; Dhume, K.; Finn, C. M.; Hwang, J. H.; Castonguay, C.; Swain, S. L.; McKinstry, K. K.

Pathogen Recognition by CD4 Effectors Drives Key Effector and Most Memory Cell Generation Against Respiratory Virus CD4效应物对病原体的识别驱动关键效应物和大多数记忆细胞生成抵抗呼吸病毒

FRONTIERS IN IMMUNOLOGY

IF5.9

2018-03-26

OAAI

Devarajan, Priyadharshini; Jones, Michael C.; Kugler-Umana, Olivia; Vong, Allen M.; Xia, Jingya; Swain, Susan L.

The properties of the unique age-associated B cell subset reveal a shift in strategy of immune response with age

CELLULAR IMMUNOLOGY

IF2.9

2017-11-01

OAAI

Swain, Susan L.; Kugler-Umana, Olivia; Kuang, Yi; Zhang, Wenliang

IL-6 Production by TLR-Activated APC Broadly Enhances Aged Cognate CD4 Helper and B Cell Antibody Responses In Vivo

JOURNAL OF IMMUNOLOGY

IF3.4

2017-04-01

OAAI

Brahmakshatriya, Vinayak; Kuang, Yi; Devarajan, Priyadharshini; Xia, Jingya; Zhang, Wenliang; Allen Minh Vong; Swain, Susan L.

NKG2C/E Marks the Unique Cytotoxic CD4 T Cell Subset, ThCTL, Generated by Influenza Infection

JOURNAL OF IMMUNOLOGY

IF3.4

2017-02-01

OAAI

Marshall, Nikki B.; Vong, Allen M.; Devarajan, Priyadharshini; Brauner, Matthew D.; Kuang, Yi; Nayar, Ribhu; Schutten, Elizabeth A.; Castonguay, Catherine H.; Berg, Leslie J.; Nutt, Stephen L.; Swain, Susan L.

Short-Lived Antigen Recognition but Not Viral Infection at a Defined Checkpoint Programs Effector CD4 T Cells To Become Protective Memory

JOURNAL OF IMMUNOLOGY

IF3.4

2016-11-15

OAAI

Bautista, Bianca L.; Devarajan, Priyadharshini; McKinstry, K. Kai; Strutt, Tara M.; Vong, Allen M.; Jones, Michael C.; Kuang, Yi; Mott, Daniel; Swain, Susan L.

Direct IL-6 Signals Maximize Protective Secondary CD4 T Cell Responses against Influenza

JOURNAL OF IMMUNOLOGY

IF3.4

2016-10-15

OAAI

Strutt, Tara M.; McKinstry, Karl Kai; Kuang, Yi; Finn, Caroline M.; Hwang, Ji Hae; Dhume, Kunal; Sell, Stewart; Swain, Susan L.

PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion (vol 44, pg 1190, 2016)

IMMUNITY

IF26.3

2016-06-01

OAAI

Tinoco, Roberto; Carrette, Florent; Barraza, Monique L.; Otero, Dennis C.; Magana, Jonathan; Bosenberg, Marcus W.; Swain, Susan L.; Bradley, Linda M.