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R

Roland Brosch

Institut Pasteur
H指数:83
被引数:3.1万

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Marine sponge microbe provides insights into evolution and virulence of the tubercle bacillus

海洋海绵微生物为结核杆菌的进化和毒力提供了见解

PLOS PATHOGENS
IF4.9
2024-08-291
OAAI
Pidot, Sacha J.; Klatt, Stephan; Ates, Louis S.; Frigui, Wafa; Sayes, Fadel; Majlessi, Laleh; Izumi, Hiroshi; Monk, Ian R.; Porter, Jessica L.; Bennett-Wood, Vicki; Seemann, Torsten; Otter, Ashley; Taiaroa, George; Cook, Gregory M.; West, Nicholas; Tobias, Nicholas J.; Fuerst, John A.; Stutz, Michael D.; Pellegrini, Marc; McConville, Malcolm; Brosch, Roland; Stinear, Timothy P.
Natural mutations in the sensor kinase of the PhoPR two-component regulatory system modulate virulence of ancestor-like tuberculosis bacilli

PhoPR双组分调节系统的传感器激酶中的自然突变调节祖先样结核杆菌的毒力

PLOS PATHOGENS
IF4.9
2023-07-145
OAAI
Malaga, Wladimir; Payros, Delphine; Meunier, Eva; Frigui, Wafa; Sayes, Fadel; Pawlik, Alexandre; Orgeur, Mickael; Berrone, Celine; Moreau, Flavie; Mazeres, Serge; Gonzalo-Asensio, Jesus; Rengel, David; Martin, Carlos; Astarie-Dequeker, Catherine; Mourey, Lionel; Brosch, Roland; Guilhot, Christophe
A lentiviral vector expressing a dendritic cell-targeting multimer induces mucosal anti-mycobacterial CD4+ T-cell immunity

表达树突状细胞靶向多聚体的慢病毒载体诱导粘膜抗分枝杆菌CD4 T细胞免疫

MUCOSAL IMMUNOLOGY
IF7.6
2022-11-015
OAAI
Anna, Francois; Lopez, Jodie; Moncoq, Fanny; Blanc, Catherine; Authie, Pierre; Noirat, Amandine; Fert, Ingrid; Souque, Philippe; Nevo, Fabien; Pawlik, Alexandre; Hardy, David; Goyard, Sophie; Hudrisier, Denis; Brosch, Roland; Guinet, Francoise; Neyrolles, Olivier; Charneau, Pierre; Majlessi, Laleh
A lentiviral vector encoding fusion of light invariant chain and mycobacterial antigens induces protective CD4+ T cell immunity

编码轻链恒定链和分枝杆菌抗原融合的慢病毒载体诱导保护性CD4 T细胞免疫

CELL REPORTS
IF6.9
2022-07-0111
OA
Lopez, Jodie; Anna, Francois; Authie, Pierre; Pawlik, Alexandre; Ku, Min-Wen; Blanc, Catherine; Souque, Philippe; Moncoq, Fanny; Noirat, Amandine; Hardy, David; Sougakoff, Wladimir; Brosch, Roland; Guinet, Francoise; Charneau, Pierre; Majlessi, Laleh
The C terminus of the mycobacterium ESX-1 secretion system substrate ESAT-6 is required for phagosomal membrane damage and virulence

分枝杆菌ESX-1分泌系统的C末端底物ESAT-6是吞噬膜损伤和毒力所必需的

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2022-03-1022
OAAI
Osman, Morwan M.; Shanahan, Jonathan K.; Chu, Frances; Takaki, Kevin K.; Pinckert, Malte L.; Pagan, Antonio J.; Brosch, Roland; Conrad, William H.; Ramakrishnan, Lalita
The Mycobacterium tuberculosis PhoPR virulence system regulates expression of the universal second messenger c-di-AMP and impacts vaccine safety and efficacy

结核分枝杆菌PhoPR毒力系统调节通用第二信使c-di-amp的表达并影响疫苗的安全性和有效性

MOLECULAR THERAPY-NUCLEIC ACIDS
IF0
2022-03-0112
OAAI
Perez, Irene; Campos-Pardos, Elena; Diaz, Caridad; Uranga, Santiago; Sayes, Fadel; Vicente, Francisca; Aguilo, Nacho; Brosch, Roland; Martin, Carlos; Gonzalo-Asensio, Jesus
IL-1R1-Dependent Signals Improve Control of Cytosolic Virulent Mycobacteria In Vivo

IL-1R1-Dependent信号改善体内胞质毒力分枝杆菌的控制

MSPHERE
IF3.1
2021-06-303
OAAI
van der Niet, Sanne; van Zon, Maaike; de Punder, Karin; Grootemaat, Anita; Rutten, Sofie; Moorlag, Simone J. C. F. M.; Houben, Diane; van der Sar, Astrid M.; Bitter, Wilbert; Brosch, Roland; Pando, Rogelio Hernandez; Pena, Maria T.; Peters, Peter J.; Reits, Eric A.; Mayer-Barber, Katrin D.; van der Wel, Nicole N.
Mucosal delivery of ESX-1-expressing BCG strains provides superior immunity against tuberculosis in murine type 2 diabetes

ESX-1-expressing BCG菌株的粘膜递送可在小鼠2型糖尿病中提供针对结核病的优异免疫力

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2020-08-1013
OAAI
Sathkumara, Harindra D.; Muruganandah, Visai; Cooper, Martha M.; Field, Matt A.; Alim, Md Abdul; Brosch, Roland; Ketheesan, Natkunam; Govan, Brenda; Rush, Catherine M.; Henning, Lars; Kupz, Andreas

研究方向

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L
Laleh Majlessi
H 指数:38论文数:109被引数:6,474
W
Wafa Frigui
H 指数:24论文数:57被引数:3,532
S
Stewart T. Cole
H 指数:113论文数:497被引数:5.5万
A
Alexandre Pawlik
H 指数:21论文数:58被引数:2,035
P
Priscille Brodin
H 指数:55论文数:172被引数:1.4万
F
Fadel Sayes
H 指数:17论文数:39被引数:2,126
D
Daria Bottai
H 指数:33论文数:75被引数:4,258
R
Roxane Siméone
H 指数:26论文数:36被引数:4,418
M
Mickael Orgeur
H 指数:19论文数:75被引数:1,782
C
Claude Leclerc
H 指数:71论文数:361被引数:1.6万