未登录 分享 收藏
Marine sponge microbe provides insights into evolution and virulence of the tubercle bacillus 海洋海绵微生物为结核杆菌的进化和毒力提供了见解 Pidot, Sacha J.; Klatt, Stephan; Ates, Louis S.; Frigui, Wafa; Sayes, Fadel; Majlessi, Laleh; Izumi, Hiroshi; Monk, Ian R.; Porter, Jessica L.; Bennett-Wood, Vicki; Seemann, Torsten; Otter, Ashley; Taiaroa, George; Cook, Gregory M.; West, Nicholas; Tobias, Nicholas J.; Fuerst, John A.; Stutz, Michael D.; Pellegrini, Marc; McConville, Malcolm; Brosch, Roland; Stinear, Timothy P. 分享 收藏
分享 收藏
分享 收藏
Natural mutations in the sensor kinase of the PhoPR two-component regulatory system modulate virulence of ancestor-like tuberculosis bacilli PhoPR双组分调节系统的传感器激酶中的自然突变调节祖先样结核杆菌的毒力 Malaga, Wladimir; Payros, Delphine; Meunier, Eva; Frigui, Wafa; Sayes, Fadel; Pawlik, Alexandre; Orgeur, Mickael; Berrone, Celine; Moreau, Flavie; Mazeres, Serge; Gonzalo-Asensio, Jesus; Rengel, David; Martin, Carlos; Astarie-Dequeker, Catherine; Mourey, Lionel; Brosch, Roland; Guilhot, Christophe 分享 收藏
A comprehensive update to the Mycobacterium tuberculosis H37Rv reference genome (vol 13, 7068, 2022) 结核分枝杆菌H37Rv参考基因组的全面更新 (第13卷，7068，2022) Chitale, Poonam; Lemenze, Alexander D.; Fogarty, Emily C.; Shah, Avi; Grady, Courtney; Odom-Mabey, Aubrey R.; Johnson, W. Evan; Yang, Jason H.; Eren, A. Murat; Brosch, Roland; Kumar, Pradeep; Alland, David 分享 收藏
A comprehensive update to the Mycobacterium tuberculosis H37Rv reference genome 结核分枝杆菌H37Rv参考基因组的全面更新 Chitale, Poonam; Lemenze, Alexander D.; Fogarty, Emily C.; Shah, Avi; Grady, Courtney; Odom-Mabey, Aubrey R.; Johnson, W. Evan; Yang, Jason H.; Eren, A. Murat; Brosch, Roland; Kumar, Pradeep; Alland, David 分享 收藏
A lentiviral vector expressing a dendritic cell-targeting multimer induces mucosal anti-mycobacterial CD4+ T-cell immunity 表达树突状细胞靶向多聚体的慢病毒载体诱导粘膜抗分枝杆菌CD4 T细胞免疫 Anna, Francois; Lopez, Jodie; Moncoq, Fanny; Blanc, Catherine; Authie, Pierre; Noirat, Amandine; Fert, Ingrid; Souque, Philippe; Nevo, Fabien; Pawlik, Alexandre; Hardy, David; Goyard, Sophie; Hudrisier, Denis; Brosch, Roland; Guinet, Francoise; Neyrolles, Olivier; Charneau, Pierre; Majlessi, Laleh 分享 收藏
A lentiviral vector encoding fusion of light invariant chain and mycobacterial antigens induces protective CD4+ T cell immunity 编码轻链恒定链和分枝杆菌抗原融合的慢病毒载体诱导保护性CD4 T细胞免疫 Lopez, Jodie; Anna, Francois; Authie, Pierre; Pawlik, Alexandre; Ku, Min-Wen; Blanc, Catherine; Souque, Philippe; Moncoq, Fanny; Noirat, Amandine; Hardy, David; Sougakoff, Wladimir; Brosch, Roland; Guinet, Francoise; Charneau, Pierre; Majlessi, Laleh 分享 收藏
分享 收藏
The Mycobacterium tuberculosis PhoPR virulence system regulates expression of the universal second messenger c-di-AMP and impacts vaccine safety and efficacy 结核分枝杆菌PhoPR毒力系统调节通用第二信使c-di-amp的表达并影响疫苗的安全性和有效性 Perez, Irene; Campos-Pardos, Elena; Diaz, Caridad; Uranga, Santiago; Sayes, Fadel; Vicente, Francisca; Aguilo, Nacho; Brosch, Roland; Martin, Carlos; Gonzalo-Asensio, Jesus 分享 收藏
IL-1R1-Dependent Signals Improve Control of Cytosolic Virulent Mycobacteria In Vivo IL-1R1-Dependent信号改善体内胞质毒力分枝杆菌的控制 van der Niet, Sanne; van Zon, Maaike; de Punder, Karin; Grootemaat, Anita; Rutten, Sofie; Moorlag, Simone J. C. F. M.; Houben, Diane; van der Sar, Astrid M.; Bitter, Wilbert; Brosch, Roland; Pando, Rogelio Hernandez; Pena, Maria T.; Peters, Peter J.; Reits, Eric A.; Mayer-Barber, Katrin D.; van der Wel, Nicole N. 分享 收藏
分享 收藏
分享 收藏
Pathogenomic analyses of Mycobacterium microti, an ESX-1-deleted member of the Mycobacterium tuberculosis complex causing disease in various hosts 在各种宿主中引起疾病的结核分枝杆菌复合体的ESX-1-deleted成员-微分枝杆菌的病原学分析 Orgeur, Mickael; Frigui, Wafa; Pawlik, Alexandre; Clark, Simon; Williams, Ann; Ates, Louis S.; Ma, Laurence; Bouchier, Christiane; Parkhill, Julian; Brodin, Priscille; Brosch, Roland 分享 收藏
分享 收藏
Mucosal delivery of ESX-1-expressing BCG strains provides superior immunity against tuberculosis in murine type 2 diabetes ESX-1-expressing BCG菌株的粘膜递送可在小鼠2型糖尿病中提供针对结核病的优异免疫力 Sathkumara, Harindra D.; Muruganandah, Visai; Cooper, Martha M.; Field, Matt A.; Alim, Md Abdul; Brosch, Roland; Ketheesan, Natkunam; Govan, Brenda; Rush, Catherine M.; Henning, Lars; Kupz, Andreas 分享 收藏
The antibiotic bedaquiline activates host macrophage innate immune resistance to bacterial infection 抗生素bedaquiline激活宿主巨噬细胞对细菌感染的先天免疫抵抗力 Giraud-Gatineau, Alexandre; Coya, Juan Manuel; Maure, Alexandra; Biton, Anne; Thomson, Michael; Bernard, Elliott M.; Marrec, Jade; Gutierrez, Maximiliano G.; Larrouy-Maumus, Gerald; Brosch, Roland; Gicquel, Brigitte; Tailleux, Ludovic 分享 收藏
Live attenuated TB vaccines representing the three modern Mycobacterium tuberculosis lineages reveal that the Euro-American genetic background confers optimal vaccine potential 代表三种现代结核分枝杆菌谱系的减毒活结核病疫苗揭示了欧美遗传背景赋予最佳疫苗潜力 Perez, Irene; Uranga, Santiago; Sayes, Fadel; Frigui, Wafa; Samper, Sofia; Arbues, Ainhoa; Aguilo, Nacho; Brosch, Roland; Martin, Carlos; Gonzalo-Asensio, Us 分享 收藏
分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
