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C

Cindy J. Castelle

metagenomi therapeutics
H指数:34
被引数:1.1万

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Comparative characterization of Cas12f orthologs reveals mechanistic features underlying enhanced genome editing efficiency

Cas12f直系同源物的比较表征揭示了增强基因组编辑效率的机制特征

NATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
2026-04-130
OAAI
Kaoling Guan; Rodrigo Fregoso Ocampo; Paula B. Matheus Carnevali; Cindy J. Castelle; Liliana Gonzalez-Osorio; Dominic T. Castanzo; Nicole C. Thomas; Molly Brothers; Tyler L. Dangerfield; Matthew M. Hooper; Madeline S. West; Nathan M. Appleby; Isabella Krudop; Rebecca C. Lamothe; Daniela S. Aliaga Goltsman; Lisa M. Alexander; Cristina N. Butterfield; Kenneth A. Johnson; Christopher T. Brown; David W. Taylor
Integration of therapeutic cargo into the human genome with programmable type V-K CAST

利用可编程V-K型CAST将治疗性载荷整合到人类基因组中

NATURE COMMUNICATIONS
IF15.7
2025-03-131
OA
Liu, Jason; Goltsman, Daniela S. Aliaga; Alexander, Lisa M.; Khayi, Khak Khak; Hong, Jennifer H.; Dunham, Drew T.; Romano, Christine A.; Temoche-Diaz, Morayma M.; Chadha, Shailaja; Ocampo, Rodrigo Fregoso; Oki-O'Connell, Jennifer; Janson, Owen P.; Turcios, Keirstinne; Gonzalez-Osorio, Liliana; Muysson, Jared; Rahman, Jenat; Laperriere, Sarah M.; Devoto, Audra E.; Castelle, Cindy J.; Butterfield, Cristina N.; Cost, Gregory J.; Brown, Christopher T.; Thomas, Brian C.
Diverse microbiome functions, limited temporal variation and substantial genomic conservation within sedimentary and granite rock deep underground research laboratories
ENVIRONMENTAL MICROBIOME
IF5.4
2024-12-180
OAAI
Amano, Yuki; Sachdeva, Rohan; Gittins, Daniel; Anantharaman, Karthik; Lei, Shufei; Valentin-Alvarado, Luis E.; Diamond, Spencer; Beppu, Hikari; Iwatsuki, Teruki; Mochizuki, Akihito; Miyakawa, Kazuya; Ishii, Eiichi; Murakami, Hiroaki; Jaffe, Alexander L.; Castelle, Cindy; Lavy, Adi; Suzuki, Yohey; Banfield, Jillian F.
Novel and Engineered Type II CRISPR Systems from Uncultivated Microbes with Broad Genome Editing Capability
CRISPR JOURNAL
IF4
2023-06-012
OAAI
Alexander, Lisa M. M.; Goltsman, Daniela S. Aliaga S.; Liu, Jason; Lin, Jyun-Liang; Temoche-Diaz, Morayma M. M.; Laperriere, Sarah M. M.; Neerincx, Andreas; Bednarski, Christien; Knyphausen, Philipp; Cohnen, Andre; Albers, Justine; Gonzalez-Osorio, Liliana; Ocampo, Rodrigo Fregoso; Oki, Jennifer; Devoto, Audra E. E.; Castelle, Cindy J. J.; Lamothe, Rebecca C. C.; Cost, Gregory J. J.; Butterfield, Cristina N. N.; Thomas, Brian C. C.; Brown, Christopher T. T.

研究方向

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J
Jillian F. Banfield
H 指数:154论文数:953被引数:9.4万
B
Brian C. Thomas
H 指数:70论文数:171被引数:2.3万
I
Itai Sharon
H 指数:41论文数:97被引数:1.3万
C
Christopher T. Brown
H 指数:41论文数:149被引数:1.4万
K
Kenneth H. Williams
H 指数:62论文数:699被引数:1.6万
L
Laura Hug
H 指数:34论文数:185被引数:1.1万
K
Kelly Wrighton
H 指数:50论文数:488被引数:1.4万
K
Karthik Anantharaman
H 指数:51论文数:248被引数:1.5万
S
Susannah G. Tringe
H 指数:90论文数:337被引数:4.2万
A
Alexander L. Jaffe
H 指数:17论文数:74被引数:2,049