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陈

陈丽昆 (Likun Chen)

State Key Laboratory of Oncology in South China邮箱:chenlk@sysucc.org.cn
H指数:27
被引数:2,767

个人简介

1996年毕业于中山医科大学临床医学系，1999年获中山大学肿瘤学硕士学位，2006年获中山大学肿瘤学博士学位。1999年至今在中山大学肿瘤防治中心内科工作。2015年至2016年赴美国佛罗里达大学医学院进修。在肺癌治疗领域深入研究，尤其关注肺癌脑转移的临床和基础研究。牵头国家自然科学及广东省自然科学基金项目，负责及参加多项肿瘤学省级及国家级研究项目，以及国际及国内多中心肿瘤学新药临床研究项目。在国内外杂志发表相关论文60余篇。

教育背景

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工作经历

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荣誉奖项

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Izalontamab brengitecan (Iza-bren; BL-B01D1), a first-in-class EGFR-HER3 bispecific antibody–drug conjugate, for patients with EGFR-mutated NSCLC: Pooled analysis of phase 1 and phase 2 trials

Izalontamab brengitecan (Iza-bren; BL-B01D1)，一流的EGFR-HER3双特异性抗体-药物偶联物，用于EGFR突变的NSCLC患者: 1期和2期试验的汇总分析

Annals of Oncology
IF65.4
2026-01-270
PRE
S.-D. Hong; Y.-S. Wang; H.-Y. Zhao; Y.-Y. Zhao; Q.-M. Wang; Y.-X. Ma; Y.-S. Li; Y. Huang; Y.-P. Yang; Z.-M. Fu; L.-K. Chen; F. Zhou; J. Yang; X.-Y. Li; X. Hou; N.-N. Zhou; L.-H. Sun; G.-F. Zhang; J.-W. Cui; L. Wu
Bevacizumab plus chemotherapy versus chemotherapy in untreated advanced non-squamous non-small-cell lung cancer patients with brain metastases (BAP BRAIN): an open-label, randomized, multicenter, phase III study

贝伐珠单抗联合化疗与化疗对比治疗未经治疗的伴有脑转移的晚期非鳞非小细胞肺癌患者（BAP BRAIN）：一项开放标签、随机、多中心、III期研究

ESMO Open
IF8.3
2025-11-200
OAAI
M. Li; Y. Pan; G. Jiang; Q. Wang; G. Wu; W. Feng; C. Zhou; Q. Bu; S. Ma; H. Jiang; J. Chen; H. Yu; M. Yu; Q. Liu; X. Hou; L. Chen
First-line camrelizumab plus pemetrexed and carboplatin for advanced non-squamous non-small-cell lung cancer with brain metastases (CAP-BRAIN): final results of a multicentre, open-label, single-arm, phase 2 trial in China

一线卡瑞利珠单抗联合培美曲塞和卡铂治疗伴脑转移的晚期非鳞非小细胞肺癌（CAP-BRAIN）：一项在中国进行的多中心、开放标签、单臂、II期试验的最终结果

eClinicalMedicine
IF10
2025-11-120
OAAI
Xue Hou; Chengzhi Zhou; Guowu Wu; Wen Lin; Zhanhong Xie; Haibo Zhang; Jiqun Yi; Jingye Lv; Fengzhuo Cheng; Fenglin She; Likun Chen
Ivonescimab Plus Chemotherapy in Non-Small Cell Lung Cancer With EGFR Variant A Randomized Clinical Trial

Ivonescimab联合化疗治疗EGFR变异的非小细胞肺癌随机临床试验

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
IF55
2024-08-209
OA
Fang, Wenfeng; Zhao, Yuanyuan; Luo, Yongzhong; Yang, Runxiang; Huang, Yan; He, Zhiyong; Zhao, Hui; Li, Mingjun; Li, Kai; Song, Qibing; Du, Xiaobo; Sun, Yulan; Li, Wei; Xu, Fei; Wang, Zhiyu; Yang, Kunning; Fan, Yun; Liu, Baogang; Zhao, Hongyun; Hu, Ying; Jia, Li; Xu, Shen; Yi, Tienan; Lv, Dongqing; Lan, Haitao; Li, Mengxia; Liang, Wenhua; Wang, Yongsheng; Yang, Hui; Jia, Yuming; Chen, Yuan; Lu, Junguo; Feng, Jifeng; Liu, Chunling; Zhou, Ming; Zhou, Jianya; Liu, Xianling; Zhou, Ningning; He, Ming; Dong, Xiaorong; Chen, Hualin; Chen, Yongxing; Su, Haichuan; Li, Xiaoling; Zhang, Zhihong; Yang, Lei; Cheng, Ying; Chen, Likun; Hou, Xue; Zhang, Yu; Guo, Jun; Wang, Zhen; Lu, Hong; Wu, Di; Feng, Weineng; Li, Wen; Huang, Jianan; Wang, Yan; Song, Xia; Peng, Jiewen; Liu, Laiyu; Guo, Yubiao; Li, Wenting; Lu, Dongmei; Hu, Mingxiu; Wang, Zhongmin Maxwell; Li, Baiyong; Xia, Michelle; Zhang, Li
Dynamic monitoring of cerebrospinal fluid circulating tumor DNA to identify unique genetic profiles of brain metastatic tumors and better predict intracranial tumor responses in non-small cell lung cancer patients with brain metastases: a prospective cohort study (GASTO 1028) (vol 20, 398, 2022)
BMC MEDICINE
IF8.3
2023-01-082
OAAI
Li, Meichen; Chen, Jing; Zhang, Baishen; Yu, Juan; Wang, Na; Li, Delan; Shao, Yang; Zhu, Dongqin; Liang, Chuqiao; Ma, Yutong; Ou, Qiuxiang; Hou, Xue; Chen, Likun

研究方向

肿瘤内科治疗抗癌药物研究靶向治疗免疫治疗
X
Xue Hou
H 指数:34论文数:163被引数:5,235
M
Meichen Li
H 指数:14论文数:58被引数:546
B
Baishen Zhang
H 指数:8论文数:28被引数:256
D
Delan Li
H 指数:8论文数:27被引数:511
符
符立梧
H 指数:60论文数:371被引数:1.3万
J
Jing Chen
H 指数:33论文数:394被引数:5,836
C
Chengzhi Zhou
H 指数:42论文数:336被引数:6,001
H
Hongsheng Wang
H 指数:47论文数:233被引数:8,151
Z
Zhuojia Chen
H 指数:31论文数:103被引数:3,773
F
Fang Wang
H 指数:42论文数:266被引数:6,479