Chunling Hu - Publications, H-index & Citations

Chunling Hu

Mayo Clinic

41H指数

400论文数

7.1K被引数

收录论文 75

发表时间

Combining multiplexed assays of variant effect for enhanced BRCA2 variant classification 结合变异效应的多重检测方法以增强BRCA2变异分类

Nature Communications

IF15.7

2026-04-09

OAAI

Chunling Hu; Sounak Sahu; Wenan Chen; Melissa Galloux; Marcy E. Richardson; Megan F. Bishop; Rachid Karam; Tina Pesaran; Jie Na; Huaizhi Huang; Jeffrey N. Weitzel; Katherine N. Nathanson; Siddhartha Yadav; Nicholas J. Boddicker; Susan M. Domchek; Alvaro N. Monteiro; Edwin S. Iversen; Shyam K. Sharan; Fergus J. Couch

Site-saturation functional screens identify PALB2 missense variants associated with increased breast cancer risk 位点饱和度功能筛选确定与乳腺癌风险增加相关的PALB2错义变异

Nature Communications

IF15.7

2026-01-19

OAAI

Rick A.C.M. Boonen; Sabine C. Knaup; Roberta Menafra; Merel E. Braspenning; Magdalena B. Rother; Petra Kleiblova; Marketa Janatova; Dina Ruano; Chunling Hu; Huaizhi Huang; Vijai Joseph; Michael Conry; Stephan Heijl; Bas Vroling; Jelle J. Goeman; Matthew Varga; Marcy E. Richardson; Susan L. Kloet; Fergus J. Couch; Maaike P. G. Vreeswijk; Haico van Attikum

Single-cell resolution of an open chromatin signature in persister tumor cells 持久性肿瘤细胞中开放染色质特征的单细胞分辨率

Cell Reports

IF6.9

2026-01-03

OAAI

Mihai Gabriel Dumbrava; Wazim Mohammed Ismail; Leticia Sandoval; Amelia Mazzone; Syed Mohammed Musheer Aalam; Megan L. Ritting; Xiaonan Hou; Yiwen Xie; Sierra Hamernick; Chunling Hu; Fergus J. Couch; Shariska P. Harrington; Scott H. Kaufmann; Nagarajan Kannan; S. John Weroha; Alexandre Gaspar-Maia

BRCA1-, BRCA2-, and PALB2-related Fanconi anemia: Scope to expand disease phenotypic features and predict breast cancer risk in heterozygotes BRCA1-、BRCA2-和PALB2相关的范可尼贫血：扩展疾病表型特征并预测杂合子乳腺癌风险的潜力

The American Journal of Human Genetics

IF0

2025-10-30

PREAI

Sharon E. Johnatty; Emma Tudini; Michael T. Parsons; Kyriaki Michailidou; Maria Zanti; Daffodil M. Canson; Aimee L. Davidson; Tamar Berger; Rasim Ozgur Rosti; Christian P. Kratz; Reinhard Kalb; Lisa J. McReynolds; Neelam Giri; Marcy E. Richardson; Tina Pesaran; Jordi Surrallés; Roser Pujol; Babu Rao Vundinti; Merin George; Kara N. Maxwell; Kate Nathanson; Susan Domchek; Moisés Ó. Fiesco-Roa; Sara Frias; Benilde García-de-Teresa; Marjolijn Jongmans; Seema Lalani; Merel Maiburg; Katrina Prescott; Rachel Robinson; Sulekha Rajagopalan; Lot Snijders Blok; Suzanna E.L. Temple; Kathy Tucker; Arleen D. Auerbach; Maria I. Cancio; Jennifer A. Kennedy; Margaret L. MacMillan; Rebecca Tryon; John E. Wagner; Michael Walsh; Nicholas J. Boddicker; Chunling Hu; Jeffrey N. Weitzel; Alexander J.M. Dingemans; Johanna Hadler; Nitsan Rotenberg; Lobna Ramadane-Morchadi; Miguel de la Hoya; Paul James; Thomas Van Overeem Hansen; Maaike P.G. Vreeswijk; Logan C. Walker; Shyam K. Sharan; Douglas F. Easton; Fergus Couch; Agata Smogorzewska; Adam Nelson; Joanne Ngeow; Marc Tischkowitz; Encarnacion Gomez-Garcia; Amanda B. Spurdle

Large-scale meta-analysis and precision functional assays identify FANCM regions in which PTVs confer different risks for ER-negative and triple-negative breast cancer 大规模元分析和精确功能测定识别出FANCM区域，其中致病性体细胞突变（PTVs）对ER阴性和三阴性乳腺癌产生不同的风险。

The Breast

IF0

2025-10-30

OAAI

Amandine Billaud; Gisella Figlioli; Clémence Mooser; Irene Casamassima; Violette Azzoni; Jahnavi Srivatsa; Mara Colombo; Laura Caleca; Thomas U. Ahearn; Irene L. Andrulis; Antonis C. Antoniou; Matthias W. Beckmann; Sabine Behrens; Marina Bermisheva; Natalia V. Bogdanova; Manjeet K. Bolla; Bernardo Bonanni; Thomas Brüning; Nicola J. Camp; Archie Campbell; Jose E. Castelao; Melissa H. Cessna; Jenny Chang-Claude; Kamila Czene; Joe Dennis; Peter Devilee; Thilo Dörk; Alison M. Dunning; Mikael Eriksson; D.Gareth Evans; Peter A. Fasching; Jonine D. Figueroa; Marike Gabrielson; Manuela Gago-Dominguez; Anna González-Neira; Pascal Guénel; Andreas Hadjisavvas; Eric Hahnen; Ute Hamann; Peter Hillemanns; Antoinette Hollestelle; Maartje J. Hooning; Reiner Hoppe; Anthony Howell; Anna Jakubowska; Vessela N. Kristensen; Jan Lubiński; Michael Lush; Siranoush Manoukian; Dimitrios Mavroudis; Roger L. Milne; Anna Marie Mulligan; William G. Newman; Nadia Obi; Mihalis I. Panayiotidis; Guillermo Pita; Muhammad U. Rashid; Valerie Rhenius; Emmanouil Saloustros; Elinor J. Sawyer; Rita K. Schmutzler; Mitul Shah; Melissa C. Southey; Amanda B. Spurdle; Ian Tomlinson; Thérèse Truong; Qin Wang; Camilla Wendt; Paul L. Auer; Nicholas J. Boddicker; Clara Bodelon; Elizabeth S. Burnside; Fei Chen; Fergus J. Couch; Susan M. Domchek; Heather A. Eliassen; Christopher Haiman; James M. Hodge; Chunling Hu; Hongyan Huang; Sara Lindstrom; Maria Elena Martinez; Katherine L. Nathanson; Susan L. Neuhausen; Katie M. O’Brien; Janet E. Olson; Julie R. Palmer; Alpa V. Patel; Kathryn J. Ruddy; Dale P. Sandler; Lauren R. Teras; Clarice R. Weinberg; Jeffrey N. Weitzel; Stacey J. Winham; Siddhartha Yadav; Song Yao; Gary Zirpoli; Marketa Janatova; Zdenek Kleibl; Petra Kleiblova; Jana Soukupova; Qihong Zhao; Lisa Devereux; Paul A. James; Ian G. Campbell; Tu Nguyen-Dumont; James G. Dowty; Nadine Andrieu; Fabienne Lesueur; Dominique Stoppa-Lyonnet; Miguel de la Hoya; Paolo Radice; Claus Storgaard Sørensen; Paolo Peterlongo

Mutagenesis of the PALB2 WD40 domain identifies variants defective in interaction with BRCA2 and DNA repair PALB2 WD40结构域的诱变分析鉴定出与BRCA2相互作用和DNA修复缺陷相关的变异体

Journal of Biological Chemistry

IF3.9

2025-10-16

OAAI

Thiago T. Gomes; Anna Beatriz R. Elias; Chunling Hu; Thales C. Nepomuceno; Giuliana de Gregoriis; Daniel S. Chrispim; Larissa B. Skaf; Fernanda A.R.L. Szpunar; Guilherme Suarez-Kurtz; Fergus J. Couch; Alvaro N.A. Monteiro; Marcelo A. Carvalho

Pain modulates brain potentials and behavioral responses to unfairness

SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE

IF3.1

2024-11-07

OAAI

Hu, Chunling; Wu, Ruoxi; Wang, Chenbo

Development of a Breast Cancer Risk Prediction Model Integrating Monogenic, Polygenic, and Epidemiologic Risk 开发整合单基因，多基因和流行病学风险的乳腺癌风险预测模型

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

IF3.4

2024-09-11

PREAI

Kalia, Sarah S.; Boddicker, Nicholas J.; Yadav, Siddhartha; Huang, Hongyan; Na, Jie; Hu, Chunling; Ambrosone, Christine B.; Yao, Song; Haiman, Christopher A.; Chen, Fei; John, Esther M.; Kurian, Allison W.; Guo, Boya; Lindstrom, Sara; Auer, Paul; Lacey, James V.; Neuhausen, Susan L.; Martinez, Maria Elena; Sandler, Dale P.; O'Brien, Katie M.; Taylor, Jack A.; Teras, Lauren R.; Hodge, James M.; Lori, Adriana; Bodelon, Clara; Trentham-Dietz, Amy; Burnside, Elizabeth S.; Vachon, Celine M.; Winham, Stacey J.; Goldgar, David E.; Domchek, Susan M.; Nathanson, Katherine L.; Weitzel, Jeffrey N.; Couch, Fergus J.; Kraft, Peter

Susceptibility gene mutations in germline and tumors of patients with HER2-negative advanced breast cancer

NPJ BREAST CANCER

IF7.6

2024-07-13

OAAI

Fasching, Peter A.; Hu, Chunling; Hart, Steven N.; Ruebner, Matthias; Polley, Eric C.; Gnanaolivu, Rohan D.; Hartkopf, Andreas D.; Huebner, Hanna; Janni, Wolfgang; Hadji, Peyman; Tesch, Hans; Uhrig, Sabrina; Ettl, Johannes; Lux, Michael P.; Lueftner, Diana; Wallwiener, Markus; Wurmthaler, Lena A.; Goossens, Chloe; Mueller, Volkmar; Beckmann, Matthias W.; Hein, Alexander; Anetsberger, Daniel; Belleville, Erik; Wimberger, Pauline; Untch, Michael; Ekici, Arif B.; Kolberg, Hans-Christian; Hartmann, Arndt; Taran, Florin-Andrei; Fehm, Tanja N.; Wallwiener, Diethelm; Brucker, Sara Y.; Schneeweiss, Andreas; Haeberle, Lothar; Couch, Fergus J.

Ki-67 Expression in Breast Cancer associated with ATM, BRCA1, BRCA2, CHEK2 and PALB2 Pathogenic Variants

CANCER RESEARCH

IF16.6

2024-05-02

PREAI

Scheel, Robert; Choong, Grace; Rao, Tara; Boddicker, Nicholas; Hu, Chunling; Na, Jie; Kaggal, Vinod; Murphy, Sean; Giridhar, Karthik; Yasir, Saba; Goetz, Matthew; Couch, Fergus; Yadav, Siddhartha

Integration of functional data to classify BRCA1/2 missense variants: An ENIGMA project

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Lyra, Paulo; Dalcolmo, Lucas; Parsons, Michael; Nepomuceno, Thales; Brito, Samuel; Nguyen, Nam Phuong N.; de Oliveira, Geise; da Siva, Joao Paulo; Caleca, Laura; Taneja, Tanisha; Hu, Chunling; Richardson, Marcy; Rossing, Maria; Hazra, Aditi; Martins, Alexandra; Caputo, Sandrine; Millot, Gael A.; Yie, Joanne NgeowYuen; Carvalho, Marcelo A.; Cline, Melissa; Radice, Paolo; Carlsen, Rachael; Mesman, Romy; Zampiga, Valentina; Villani, Rehan; Josef, Vijay; Sharan, Shyam; Michailidou, Kyriaki; Spurdle, Amanda B.; Couch, Fergus; Vreeswijk, Maaike P. G.; Monteiro, Alvaro N.

Functional analysis and clinical classification of 462 germline BRCA2 missense variants affecting the DNA binding domain

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2024-03-01

OAAI

Hu, Chunling; Huang, Huaizhi; Na, Jie; Lumby, Carolyn; Abozaid, Mohamed; Holdren, Megan A.; Rao, Tara J.; Karam, Rachid; Pesaran, Tina; Weyandt, Jamie D.; Csuy, Christen M.; Seelaus, Christina A.; Young, Colin C.; Fulk, Kelly; Heidari, Zahra; Lyra Jr, Paulo Cilas Morais; Couch, Ronan E.; Persons, Benjamin; Polley, Eric C.; Gnanaolivu, Rohan D.; Boddicker, Nicholas J.; Monteiro, Alvaro N. A.; Yadav, Siddhartha; Domchek, Susan M.; Richardson, Marcy E.; Couch, Fergus J.

Functional and clinical characterization of hypomorphic missense variants in the BRCA2 cancer predisposition gene

CANCER RESEARCH

IF16.6

2024-02-01

PREAI

Huang, Huaizhi (Gilbert); Hu, Chunling; Na, Jie; Abozaid, Mohamed; Munankarmy, Amik; Rao, Tara; Lumby, Carolyn A. Dunn; Lyra, Paulo Cilas Morais; Couch, Ronan E.; Persons, Benjamin R.; Polley, Eric C.; Karam, Rachid; Pesaran, Tina; Yadav, Siddhartha; Monteiro, Alvaro N. A.; Boddicker, Nicholas J.; Domchek, Susan M.; Richardson, Marcy E.; Couch, Fergus J.

Germline Mutations in 12 Genes and Risk of Ovarian Cancer in Three Population-Based Cohorts

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

IF3.4

2023-07-26

OAAI

Kotsopoulos, Joanne; Hathaway, Cassandra A.; Narod, Steven A.; Teras, Lauren R.; Patel, Alpa V.; Hu, Chunling; Yadav, Siddhartha; Couch, Fergus J.; Tworoger, Shelley S.

Functional and Clinical Characterization of Variants of Uncertain Significance Identifies a Hotspot for Inactivating Missense Variants in RAD51C 意义不确定的变体的功能和临床表征确定了RAD51C中失活错义变体的热点

CANCER RESEARCH

IF16.6

2023-05-30

OAAI

Hu, Chunling; Nagaraj, Anil Belur; Shimelis, Hermela; Montalban, Gemma; Lee, Kun Y.; Huang, Huaizhi; Lumby, Carolyn A.; Na, Jie; Susswein, Lisa R.; Roberts, Maegan E.; Marshall, Megan L.; Hiraki, Susan; LaDuca, Holly; Chao, Elizabeth; Yussuf, Amal; Pesaran, Tina; Neuhausen, Susan L.; Haiman, Christopher A.; Kraft, Peter; Lindstrom, Sara; Palmer, Julie R.; Teras, Lauren R.; Vachon, Celine M.; Yao, Song; Ong, Irene; Nathanson, Katherine L.; Weitzel, Jeffrey N.; Boddicker, Nicholas; Gnanaolivu, Rohan; Polley, Eric C.; Mer, Georges; Cui, Gaofeng; Karam, Rachid; Richardson, Marcy E.; Domchek, Susan M.; Yadav, Siddhartha; Hruska, Kathleen S.; Dolinsky, Jill; Weroha, S. John; Hart, Steven N.; Simard, Jacques; Masson, Jean Yves; Pang, Yuan-Ping; Couch, Fergus J.

Mutation type and location in breast cancer susceptibility genes are associated with differential risk in the general population

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Akamandisa, Mwangala P.; Boddicker, Nicholas; Hu, Chunling; Yadav, Siddhartha; Weitzel, Jeffrey N.; Kraft, Peter; Domchek, Susan M.; Couch, Fergus J.; Nathanson, Katherine L.

Population-based Estimates of contralateral Breast Cancer Risk among Carriers of Germline Pathogenic Variants in ATM, BRCA1, BRCA2, CHEK2, and PALB2

CANCER RESEARCH

IF16.6

2023-03-01

PREAI

Yadav, Siddhartha; Boddicker, Nicholas J.; Na, Jie; Polley, Eric C.; Hu, Chunling; Hart, Steven N.; Gnanaolivu, Rohan D.; Larson, Nicole; Dunn, Carolyn; Holtegaard, Susan; Huang, Huaizhi; Teras, Lauren R.; Patel, Alpa V.; Lacey, James V., Jr.; Neuhausen, Susan; Bernstein, Leslie; Martinez, Elena; Haiman, Christopher; Chen, Fei; Ruddy, Kathryn; Olson, Janet; John, Esther; Kurian, Allison W.; Sandler, Dale P.; O'Brien, Katie M.; Taylor, Jack A.; Weinberg, Clarice R.; Anton-Culver, Hoda; Ziogas, Argyrios; Zirpoli, Gary R.; Goldgar, David E.; Nathanson, Katherine L.; Domchek, Susan; Palmer, Julie R.; Weitzel, Jeffrey; Kraft, Peter; Couch, Fergus J.

Genetic Risk of Second Primary Cancer in Breast Cancer Survivors: The Multiethnic Cohort Study

CANCER RESEARCH

IF16.6

2022-07-14

OAAI

Chen, Fei; Park, Sungshim L.; Wilkens, Lynne R.; Wan, Peggy; Hart, Steven N.; Hu, Chunling; Yadav, Siddhartha; Couch, Fergus J.; V. Conti, David; de Smith, Adam J.; Haiman, Christopher A.

Tanreqing Injection Attenuates Macrophage Activation and the Inflammatory Response via the lncRNA-SNHG1/HMGB1 Axis in Lipopolysaccharide-Induced Acute Lung Injury

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-04-25

OAAI

Hu, Chunling; Li, Junlu; Tan, Yingshuai; Liu, Yang; Bai, Chen; Gao, Jing; Zhao, Shilong; Yao, Mengying; Lu, Xiaoxiao; Qiu, Lingxiao; Xing, Lihua

Population-based risk estimates of clinical subtypes of breast cancer among carriers of germline pathogenic variants in cancer predisposition genes

CANCER RESEARCH

IF16.6

2022-02-15

PREAI

Yadav, Siddhartha; Hu, Chunling; Boddicker, Nicholas J.; Polley, Eric; Hart, Steven; Gnanaolivu, Rohan; Na, Jie; Huang, Hongyan; Yao, Song; Vachon, Celine M.; Teras, Lauren; Taylor, Jack A.; Sandler, Dale P.; Palmer, Julie R.; Olson, Janet E.; Neuhausen, Susan; Martinez, Elena; Lindstroem, Sara; Le Marchand, Loic; Kooperberg, Charles; Haiman, Christopher; Gaudet, Mia M.; Lacey, James V.; Bertrand, Kimberly A.; Bernstein, Leslie; Auer, Paul W.; Ambrosone, Christine; Weitzel, Jeffrey N.; Kraft, Peter; Goldgar, David E.; Nathanson, Katherine L.; Domchek, Susan M.; Couch, Fergus J.

研究方向