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B

Brian A. Van Tine

Washington University School of Medicine
H指数:66
被引数:4.5万

个人简介

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教育背景

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工作经历

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荣誉奖项

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Safety of the BRD9 heterobifunctional degrader CFT8634 in synovial sarcoma and SMARCB1-null tumors: an open-label, dose-escalation, phase 1 clinical trial

BRD9异双功能降解剂CFT8634在滑膜肉瘤和SMARCB1缺失肿瘤中的安全性：一项开放标签、剂量递增的1期临床试验

Communications Medicine
IF6.3
2026-08-040
OAAI
Brian A. Van Tine; William D. Tap; Mark Agulnik; Ravin Ratan; Sant P. Chawla; Steven Attia; Anthony Elias; Prabhjot Mundi; Mohammed Milhem; Joseph G. Pressey; Amro Ali; Ingrid Mintautas; Riadh Lobbardi; Huan Liu; Eunju Hurh; Len Reyno; Gregory M. Cote
Fibroblast growth factor receptor inhibition for succinate dehydrogenase-deficient gastrointestinal stromal tumors: a phase 2 trial

针对琥珀酸脱氢酶缺陷型胃肠道间质瘤的成纤维细胞生长因子受体抑制：一项2期临床试验

Nature Medicine
IF50
2026-05-260
OAAI
Priscilla Merriam; James J. Morrow; Emanuele Mazzola; Nicole L. Solimini; Prafulla C. Gokhale; Ping Chi; Alice P. Chen; Mark Agulnik; Melissa Burgess; Scott M. Schuetze; Neeta Somaiah; Brian A. Van Tine; Seth M. Pollack; Gabriel Tinoco; Jonathan Trent; Breelyn A. Wilky; Nicola Bothwick; Benjamin K. Eschle; Vivian Nguyen; Jan H. Beumer; Noushin Rastkari; Shahanawaz Jiwani; Peter I-Fan Wu; Lorraine Pelosof; Matthew L. Hemming; Geoffrey I. Shapiro; George Demetri; Bradley Bernstein; Suzanne George
Succinate Dehydrogenase B (SDHB) Overexpression with Enzymatic Dysfunction Defines a Distinct Subtype of Undifferentiated Pleomorphic Sarcoma

琥珀酸脱氢酶B (SDHB) 过表达伴随酶功能失调定义了一种未分化多形性肉瘤的独特亚型

CANCER RESEARCH COMMUNICATIONS
IF0
2025-10-010
OAAI
Esperanca-Martins, Miguel; Vasques, Hugo; Ravasqueira, Manuel Sokolov; Santos, Filipa; Fonseca, Filipa; Queiroz, Antonio Syder; Boavida, Joao; Jordao, Daniel Martins; Soares Do Brito, Joaquim; Corredeira, Patricia; Martins, Marta; Afonso, Angela; Lopez, Jorge Antonio; Huang, Richard S. P.; Melo-Alvim, Cecilia; Fernandes, Isabel; Lopez-Presa, Dolores; Lemos, Maria Manuel; Van Tine, Brian A.; Bastos, Alliny C. S.; Casimiro, Sandra; Abecasis, Nuno; Costa, Luis; Goncalves, Emanuel; Duarte, Iola F.; Dias, Sergio
A phase 4, multicenter, global clinical study to evaluate discontinuation and rechallenge of pexidartinib in patients with tenosynovial giant cell tumor previously treated with pexidartinib
CANCER
IF5.1
2024-11-121
OAAI
Desai, Jayesh; Wagner, Andrew J.; Carrasco Garcia, Irene; Cesari, Marilena; Gordon, Michael; Lin, Chia-Chi; Papai, Zsuzsanna; Ryan, Christopher W.; Tap, William D.; Trent, Jonathan C.; Gelderblom, Hans; Grimison, Peter; Lopez Pousa, Antonio; Van Tine, Brian A.; Rubinacci, Maria; Dai, Dong; Rajper, Abdul Waheed; Tecson, Kristen; Wooddell, Margaret; Stacchiotti, Silvia
A multicenter, randomized, non-comparative, phase II study of nivolumab ± ipilimumab for patients with metastatic sarcoma (Alliance A091401): expansion cohorts and correlative analyses
JOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
2024-09-280
OAAI
Seligson, Nathan D.; Chen, James L.; Goodrich, Austin C.; Van Tine, Brian A.; Campbell, Jordan D.; Richards, Allison L.; Antonescu, Cristina R.; Liebner, David A.; Milhem, Mohammed M.; Streicher, Howard; Tap, William D.; Schwartz, Gary K.; George, Suzanne; D'Angelo, Sandra P.
A Phase I/IIa clinical trial (TranStar101) to evaluate the safety, tolerability and pharmacokinetics of OSEMITAMAB administered as monotherapy or in combination with nivolumab or standard of care in patients with locally advanced or metastatic solid tumors
CANCER RESEARCH
IF16.6
2024-04-052
PRE
Janjigian, Yelena; Tolcher, Anthony; Mehta, Rutika; Cecchini, Michael; Van Tine, Brian; Kundranda, Madappa; Olatunji, Alese; Patel, Manish R.; Berlin, Jordan; Rocha-Lima, Caio Max Sao Pedro; Monga, Dulabh; Ben George; Scott, Aaron; Xia, Zhenzhong; Elsafy, Mohamed; Jones, Erikca; Yao, Zhenling; Qi, Chuan; Germa, Caroline; Gabrail, Nash
Atezolizumab clinical trial biopsies reveal varied immune landscapes in clear cell sarcoma and chondrosarcoma
CANCER RESEARCH
IF16.6
2024-04-050
PRE
Ferry-Galow, Katherine V.; Fino, Kristin K.; Coyne, Geraldine O'Sullivan; Moore, Nancy; Sharon, Elad; Burgess, Melissa; Chen, James; Conley, Anthony P.; Davis, Elizabeth J.; Merriam, Priscilla; Razak, Albiruni R. Abdul; Van Tine, Brian; Foster, Jared C.; Takebe, Naoko; Rosenberger, Christina L.; Doroshow, James H.; Chen, Alice P.; Parchment, Ralph E.
A dose escalation and cohort expansion study of the CDK9 inhibitor KB0742 in relapsed, refractory and transcriptionally addicted solid tumors
CANCER RESEARCH
IF16.6
2024-04-050
PRE
Calero, Miguel Villalona; Agulnik, Mark; Mita, Monica; Mita, Alain; Federman, Noah; Rasco, Drew; Spigel, David; Luo, Jia; Hanna, Glenn; Cote, Gregory; Salkeni, Mohamad A.; Chugh, Rashmi; Ammakkanavar, Natraj R.; Shah, Satish A.; Rao, Amol; Sankhala, Kamalesh Kumar; Cutler, Richard E.; Hood, Tressa; Carvajal, Luis; MacKenzie, Crystal; Lin, Charles; DiMartino, Jorge; Olek, Elizabeth A.; Van Tine, Brian
First-in-human, dose escalation and expansion study of MT-6402, a novel engineered toxin body (ETB) targeting PD-L1, in patients with PD-L1 expressing relapsed/refractory advanced solid tumors: Interim data
CANCER RESEARCH
IF16.6
2024-04-050
PRE
Van Tine, Brian A.; Ahn, Eugene; Redman, Rebecca A.; Barve, Minal A.; Edenfield, William J.; Peguero, Julio; Villaflor, Victoria M.; Rasco, Drew W.; Powell, Steven F.; Mamuye, Admasu T.; Moore, Chris B.; Pelham, Joshua M.; Charoenthongtrakul, Soratree; Spigel, David R.

研究方向

暂未获取到该数据
R
Robin L. Jones
H 指数:92论文数:1,576被引数:3.6万
M
Mark Agulnik
H 指数:46论文数:257被引数:1.0万
S
Steven Attia
H 指数:34论文数:224被引数:7,108
W
William D. Tap
H 指数:74论文数:923被引数:2.5万
G
Gary K. Schwartz
H 指数:97论文数:1,009被引数:3.8万
M
Mohammed Milhem
H 指数:67论文数:502被引数:5.2万
A
Angela C. Hirbe
H 指数:33论文数:413被引数:3,947
G
Gregory M. Coté
H 指数:43论文数:322被引数:6,312
P
Priscilla Merriam
H 指数:17论文数:81被引数:2,142
N
Noah Federman
H 指数:38论文数:231被引数:8,878