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Durable benefit from poly(ADP-ribose) polymerase inhibitors in metastatic prostate cancer in routine practice: biomarker associations and implications for optimal clinical next-generation sequencing testing Triner, D.; Graf, R. P.; Madison, R. W.; Gjoerup, O.; Tukachinsky, H.; Ross, J. S.; Quintanilha, J. C. F.; Li, G.; Cheng, H. H.; Pritchard, C. C.; Zurita, A. J.; Qin, Q.; Zhang, T.; Agarwal, N.; Reichert, Z. R.; Mateo, J.; Cieslik, M.; Morgan, T. M. 分享 收藏
Effectiveness of PARP Inhibitor Maintenance Therapy in Ovarian Cancer by BRCA1/2 and a Scar-Based HRD Signature in Real-World Practice Richardson, Debra L.; Quintanilha, Julia C. F.; Danziger, Natalie; Li, Gerald; Sokol, Ethan; Schrock, Alexa B.; Ebot, Ericka; Bhardwaj, Neeru; Norris, Tanesha; Afghahi, Anosheh; Frachioni, Anthony; Washington, Christina; Dockery, Lauren; Elvin, Julia; Graf, Ryon P.; Moore, Kathleen N. 分享 收藏
Comprehensive genomic profiling of ESR1, PIK3CA, AKT1, and PTEN in HR(+)HER2(-) metastatic breast cancer: prevalence along treatment course and predictive value for endocrine therapy resistance in real-world practice (June, 10.1007/s10549-024-07427-2, 2024) Bhave, Manali A.; Quintanilha, Julia C. F.; Tukachinsky, Hanna; Li, Gerald; Scott, Takara; Ross, Jeffrey S.; Pasquina, Lincoln; Huang, Richard S. P.; McArthur, Heather; Levy, Mia A.; Graf, Ryon P.; Kalinsky, Kevin 分享 收藏
Comprehensive genomic profiling of ESR1, PIK3CA, AKT1, and PTEN in HR(+)HER2(-) metastatic breast cancer: prevalence along treatment course and predictive value for endocrine therapy resistance in real-world practice Bhave, Manali A.; Quintanilha, Julia C. F.; Tukachinsky, Hanna; Li, Gerald; Scott, Takara; Ross, Jeffrey S.; Pasquina, Lincoln; Huang, Richard S. P.; Mcarthur, Heather; Levy, Mia A.; Graf, Ryon P.; Kalinsky, Kevin 分享 收藏
ESR1 mutations (ESR1mut) in HR(+)HER2(-)patients with metastatic breast cancer (MBC): prevalence along treatment course and predictive value for endocrine therapy (ET) resistance in real-world practice Bhave, Manali; Quintanilha, Julia; Graf, Ryon; Scott, Takara; Tukachinsky, Hanna; Li, Gerald; Schrock, Alexa; Oxnard, Geoffrey; Levy, Mia; Kalinsky, Kevin 分享 收藏
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Durable responders in advanced NSCLC with elevated TMB and treated with 1L immune checkpoint inhibitor: a real-world outcomes analysis Huang, Richard S. P.; Carbone, David P.; Li, Gerald; Schrock, Alexa; Graf, Ryon P.; Zhang, Liangliang; Murugesan, Karthikeyan; Ross, Jeffrey S.; Tolba, Khaled; Sands, Jacob; Oxnard, Geoffrey R.; Spigel, David 分享 收藏
Prognostic value of plasma circulating tumor DNA fraction across four common cancer types: a real-world outcomes study Reichert, Z. R.; Morgan, T. M.; Li, G.; Castellanos, E.; Snow, T.; Dall'Olio, F. G.; Madison, R. W.; Fine, A. D.; Oxnard, G. R.; Graf, R. P.; Stover, D. G. 分享 收藏
SPOP Mutations as a Predictive Biomarker for Androgen Receptor Axis-Targeted Therapy in De Novo Metastatic Castration-Sensitive Prostate Cancer Swami, Umang; Graf, Ryon P.; Nussenzveig, Roberto H.; Fisher, Virginia; Tukachinsky, Hanna; Schrock, Alexa B.; Li, Gerald; Ross, Jeffrey S.; Sayegh, Nicolas; Tripathi, Nishita; Thomas, Vinay Mathew; Oxnard, Geoffrey R.; Antonarakis, Emmanuel S.; Agarwal, Neeraj 分享 收藏
Complementary Roles for Tissue- and Blood-Based Comprehensive Genomic Profiling for Detection of Actionable Driver Alterations in Advanced NSCLC Schwartzberg, Lee S.; Li, Gerald; Tolba, Khaled; Bourla, Ariel B.; Schulze, Katja; Gadgil, Rujuta; Fine, Alexander; Lofgren, Katherine T.; Graf, Ryon P.; Oxnard, Geoffrey R.; Daniel, Davey 分享 收藏
Somatic HLA Class I Loss Is a Widespread Mechanism of Immune Evasion Which Refines the Use of Tumor Mutational Burden as a Biomarker of Checkpoint Inibitor Response 体细胞HLA I类丢失是免疫逃避的一种广泛机制,它完善了肿瘤突变负荷作为检查点免疫反应生物标志物的用途 Montesion, Meagan; Murugesan, Karthikeyan; Jin, Dexter X.; Sharaf, Radwa; Sanchez, Nora; Guria, Ameet; Minker, Max; Li, Gerald; Fisher, Virginia; Sokol, Ethan S.; Pavlick, Dean C.; Moore, Jay A.; Braly, Alan; Singal, Gaurav; Fabrizio, David; Comment, Leah A.; Rizvi, Naiyer A.; Alexander, Brian M.; Frampton, Garrett M.; Hegde, Priti S.; Albacker, Lee A. 分享 收藏
Clinical and Genomic Characteristics of Small Cell Lung Cancer in Never Smokers Results From a Retrospective Multicenter Cohort Study Thomas, Anish; Mian, Idrees; Tlemsani, Camille; Pongor, Lorinc; Takahashi, Nobuyuki; Maignan, Kathleen; Snider, Jeremy; Li, Gerald; Frampton, Garrett; Ali, Siraj; Kim, Sehyun; Nichols, Samantha; Rajapakse, Vinodh; Guha, Udayan; Sharon, Elad; Fujimoto, Junya; Moran, Cesar A.; Wistuba, Ignacio I.; Wei, Jun S.; Khan, Javed; Szabo, Eva; Torres, Aracelis Z.; Carson, Kenneth R. 分享 收藏
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Association of Patient Characteristics and Tumor Genomics With Clinical Outcomes Among Patients With Non-Small Cell Lung Cancer Using a Clinicogenomic Database Singal, Gaurav; Miller, Peter G.; Agarwala, Vineeta; Li, Gerald; Kaushik, Gaurav; Backenroth, Daniel; Gossai, Anala; Frampton, Garrett M.; Torres, Aracelis Z.; Lehnert, Erik M.; Bourque, David; O'Connell, Claire; Bowser, Bryan; Caron, Thomas; Baydur, Ezra; Seidl-Rathkopf, Kathi; Ivanov, Ivan; Alpha-Cobb, Garrett; Guria, Ameet; He, Jie; Frank, Shannon; Nunnally, Allen C.; Bailey, Mark; Jaskiw, Ann; Feuchtbaum, Dana; Nussbaum, Nathan; Abernethy, Amy P.; Miller, Vincent A. 分享 收藏
Identification of resistance mechanisms to EGFR treatment in the real world using a clinicogenomic database Singal, Gaurav; Li, Gerald; Agarwala, Vineeta; Kaushik, Gaurav; O'Connell, Claire; Cobb, Garrett A.; Caron, Thomas; Bourque, David; Guria, Ameet; Frank, Shannon; Frampton, Garrett; Carson, Ken; Abernethy, Amy; Miller, Vincent A. 分享 收藏
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Integrated tumor identification and automated scoring minimizes pathologist involvement and provides new insights to key biomarkers in breast cancer 综合肿瘤识别和自动评分最大限度地减少了病理学家的参与,并为乳腺癌的关键生物标志物提供了新的见解 Bankhead, Peter; Fernandez, Jose A.; McArt, Darragh G.; Boyle, David P.; Li, Gerald; Loughrey, Maurice B.; Irwin, Gareth W.; Harkin, D. Paul; James, Jacqueline A.; McQuaid, Stephen; Salto-Tellez, Manuel; Hamilton, Peter W. 分享 收藏
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