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Mechanisms and management of loss of response to anti-TNF therapy for patients with Crohn's disease: 3-year data from the prospective, multicentre PANTS cohort study Chanchlani, Neil; Lin, Simeng; Bewshea, Claire; Hamilton, Benjamin; Thomas, Amanda; Smith, Rebecca; Roberts, Christopher; Bishara, Maria; Nice, Rachel; Lees, Charlie W.; Sebastian, Shaji; Irving, Peter M.; Russell, Richard K.; McDonald, Timothy J.; Goodhand, James R.; Ahmad, Tariq; Kennedy, Nicholas A. 分享 收藏
Antibody Responses to Influenza Vaccination are Diminished in Patients With Inflammatory Bowel Disease on Infliximab or Tofacitinib 使用英夫利昔单抗或托法替尼的炎症性肠病患者对流感疫苗的抗体反应减弱 Liu, Zhigang; Alexander, James L.; Eng, Kai Yee; Ibraheim, Hajir; Anandabaskaran, Sulak; Saifuddin, Aamir; Constable, Laura; Seoane, Rocio Castro; Bewshea, Claire; Nice, Rachel; D'Mello, Andrea; Jones, Gareth R.; Balarajah, Sharmili; Fiorentino, Francesca; Sebastian, Shaji; Irving, Peter M.; Hicks, Lucy C.; Williams, Horace R. T.; Kent, Alexandra J.; Linger, Rachel; Parkes, Miles; Kok, Klaartje; Patel, Kamal, V; Teare, Julian P.; Altmann, Daniel M.; Boyton, Rosemary J.; Hart, Ailsa L.; Lees, Charlie W.; Goodhand, James R.; Kennedy, Nicholas A.; Pollock, Katrina M.; Ahmad, Tariq; Powell, Nick 分享 收藏
Neutralising antibody responses against SARS-CoV-2 Omicron BA.4/5 and wild-type virus in patients with inflammatory bowel disease following three doses of COVID-19 vaccine (VIP): a prospective, multicentre, cohort study 炎症性肠病患者在三剂新型冠状病毒肺炎疫苗 (VIP) 后中和针对SARS-CoV-2 Omicron BA.4/5和野生型病毒的抗体反应: 一项前瞻性、多中心、队列研究 Liu, Zhigang; Alexander, James L.; Le, Kaixing; Zhou, Xin; Ibraheim, Hajir; Anandabaskaran, Sulak; Saifuddin, Aamir; Lin, Kathy Weitung; McFarlane, Leon R.; Constable, Laura; Seoane, Rocio Castro; Anand, Nikhil; Bewshea, Claire; Nice, Rachel; D'Mello, Andrea; Jones, Gareth R.; Balarajah, Sharmili; Fiorentino, Francesca; Sebastian, Shaji; Irving, Peter M.; Hicks, Lucy C.; Williams, Horace R. T.; Kent, Alexandra J.; Linger, Rachel; Parkes, Miles; Kok, Klaartje; Patel, Kamal V.; Teare, Julian P.; Altmann, Daniel M.; Boyton, Rosemary J.; Hart, Ailsa L.; Lees, Charlie W.; Goodhand, James R.; Kennedy, Nicholas A.; Pollock, Katrina M.; Ahmad, Tariq; Powell, Nick 分享 收藏
Baseline Expression of Immune Gene Modules in Blood is Associated With Primary Response to Anti-TNF Therapy in Crohn's Disease Patients Bai, Benjamin Y. H.; Reppell, Mark; Smaoui, Nizar; Waring, Jeffrey F.; Pivorunas, Valerie; Guay, Heath; Lin, Simeng; Chanchlani, Neil; Bewshea, Claire; Goodhand, James R.; Kennedy, Nicholas A.; Ahmad, Tariq; Anderson, Carl A. 分享 收藏
Whole Blood DNA Methylation Changes Are Associated with Anti-TNF Drug Concentration in Patients with Crohn's Disease 克罗恩病患者全血DNA甲基化改变与抗TNF药物浓度相关 Lin, Simeng; Hannon, Eilis; Reppell, Mark; Waring, Jeffrey F.; Smaoui, Nizar; Pivorunas, Valerie; Guay, Heath; Chanchlani, Neil; Bewshea, Claire; Bai, Benjamin Y. H.; Kennedy, Nicholas A.; Goodhand, James R.; Mill, Jonathan; Ahmad, Tariq 分享 收藏
Neutralising antibody potency against SARS-CoV-2 wild- type and omicron BA.1 and BA.4/5 variants in patients with inflammatory bowel disease treated with infliximab and vedolizumab after three doses of COVID-19 vaccine (CLARITY IBD): an analysis of a prospective multicentre cohort study Liu, Zhigang; Le, Kaixing; Zhou, Xin; Alexander, James L.; Lin, Simeng; Bewshea, Claire; Chanchlani, Neil; Nice, Rachel; McDonald, Timothy J.; Lamb, Christopher A.; Sebastian, Shaji; Kok, Klaartje; Lees, Charlie W.; Hart, Ailsa L.; Pollok, Richard C.; Boyton, Rosemary J.; Altmann, Daniel M.; Pollock, Katrina M.; Goodhand, James R.; Kennedy, Nicholas A.; Ahmad, Tariq; Powell, Nick 分享 收藏
The gut microbiota and metabolome are associated with diminished COVID-19 vaccine-induced antibody responses in immunosuppressed inflammatory bowel disease patients Alexander, James L.; Mullish, Benjamin H.; Danckert, Nathan P.; Liu, Zhigang; Olbei, Marton L.; Saifuddin, Aamir; Torkizadeh, Melissa; Ibraheim, Hajir; Blanco, Jesus Miguens; Roberts, Lauren A.; Bewshea, Claire M.; Nice, Rachel; Lin, Simeng; Prabhudev, Hemanth; Sands, Caroline; Horneffer-van der Sluis, Verena; Lewis, Matthew; Sebastian, Shaji; Lees, Charlie W.; Teare, Julian P.; Hart, Ailsa; Goodhand, James R.; Kennedy, Nicholas A.; Korcsmaros, Tamas; Marchesi, Julian R.; Ahmad, Tariq; Powell, Nick 分享 收藏
COVID-19 vaccine-induced antibody and T-cell responses in immunosuppressed patients with inflammatory bowel disease after the third vaccine dose (VIP): a multicentre, prospective, case-control study 免疫抑制的炎症性肠病患者在第三次疫苗剂量 (VIP) 后新型冠状病毒肺炎疫苗诱导的抗体和T细胞反应: 一项多中心，前瞻性，病例对照研究 Alexander, James L.; Liu, Zhigang; Sandoval, Diana Munoz; Reynolds, Catherine; Ibraheim, Hajir; Anandabaskaran, Sulak; Saifuddin, Aamir; Seoane, Rocio Castro; Anand, Nikhil; Nice, Rachel; Bewshea, Claire; D'Mello, Andrea; Constable, Laura; Jones, Gareth R.; Balarajah, Sharmili; Fiorentino, Francesca; Sebastian, Shaji; Irving, Peter M.; Hicks, Lucy C.; Williams, Horace R. T.; Kent, Alexandra J.; Linger, Rachel; Parkes, Miles; Kok, Klaartje; Patel, Kamal V.; Teare, Julian P.; Altmann, Daniel M.; Goodhand, James R.; Hart, Ailsa L.; Lees, Charlie W.; Boyton, Rosemary J.; Kennedy, Nicholas A.; Ahmad, Tariq; Powell, Nick 分享 收藏
Understanding anti-TNF treatment failure: Does serum triiodothyronine-to-thyroxine (T3/T4) ratio predict therapeutic outcome to anti-TNF therapies in biologic-naive patients with active luminal Crohn's disease? Lin, Simeng; Chanchlani, Neil; Carbery, Isabel; Janjua, Malik; Nice, Rachel; McDonald, Timothy J.; Bewshea, Claire; Kennedy, Nicholas A.; Ahmad, Tariq; Selinger, Christian P.; Goodhand, James R. 分享 收藏
COVID-19 vaccine-induced antibody responses in immunosuppressed patients with inflammatory bowel disease (VIP): a multicentre, prospective, case-control study 炎症性肠病 (VIP) 免疫抑制患者的新型冠状病毒肺炎疫苗诱导的抗体反应: 一项多中心，前瞻性病例对照研究 Alexander, James L.; Kennedy, Nicholas A.; Ibraheim, Hajir; Anandabaskaran, Sulak; Saifuddin, Aamir; Seoane, Rocio Castro; Liu, Zhigang; Nice, Rachel; Bewshea, Claire; D'Mello, Andrea; Constable, Laura; Jones, Gareth R.; Balarajah, Sharmili; Fiorentino, Francesca; Sebastian, Shaji; Irving, Peter M.; Hicks, Lucy C.; Williams, Horace R. T.; Kent, Alexandra J.; Linger, Rachel; Parkes, Miles; Kok, Klaartje; Patel, Kamal, V; Teare, Julian P.; Altmann, Daniel M.; Boyton, Rosemary J.; Goodhand, James R.; Hart, Ailsa L.; Lees, Charlie W.; Ahmad, Tariq; Powell, Nick 分享 收藏
Antibody decay, T cell immunity and breakthrough infections following two SARS-CoV-2 vaccine doses in inflammatory bowel disease patients treated with infliximab and vedolizumab 在接受英夫利昔单抗和维多珠单抗治疗的炎症性肠病患者中，两次SARS-CoV-2疫苗剂量后抗体衰减，T细胞免疫和突破性感染 Lin, Simeng; Kennedy, Nicholas A.; Saifuddin, Aamir; Sandoval, Diana Munoz; Reynolds, Catherine J.; Seoane, Rocio Castro; Kottoor, Sherine H.; Pieper, Franziska P.; Lin, Kai-Min; Butler, David K.; Chanchlani, Neil; Nice, Rachel; Chee, Desmond; Bewshea, Claire; Janjua, Malik; McDonald, Timothy J.; Sebastian, Shaji; Alexander, James L.; Constable, Laura; Lee, James C.; Murray, Charles D.; Hart, Ailsa L.; Irving, Peter M.; Jones, Gareth-Rhys; Kok, Klaartje B.; Lamb, Christopher A.; Lees, Charlie W.; Altmann, Daniel M.; Boyton, Rosemary J.; Goodhand, James R.; Powell, Nick; Ahmad, Tariq 分享 收藏
Adalimumab and Infliximab Impair SARS-CoV-2 Antibody Responses: Results from a Therapeutic Drug Monitoring Study in 11 422 Biologic-Treated Patients 阿达木单抗和英夫利昔单抗损害SARS-CoV-2抗体反应: 来自11名422生物治疗患者的治疗药物监测研究结果 Chanchlani, Neil; Lin, Simeng; Chee, Desmond; Hamilton, Benjamin; Nice, Rachel; Zehra, Arkir; Bewshea, Claire; Cipriano, Bessie; Derikx, Lauranne A. A. P.; Dunlop, Allan; Greathead, Louise; Griffiths, Rachel L.; Ibraheim, Hajir; Kelleher, Peter; Kok, Klaartje B.; Lees, Charlie W.; MacDonald, Jonathan; Sebastian, Shaji; Smith, Philip J.; McDonald, Timothy J.; Irving, Peter M.; Powell, Nick; Kennedy, Nicholas A.; Goodhand, James R.; Ahmad, Tariq 分享 收藏
Anti-SARS-CoV2 antibody responses are attenuated in patients with Inflammatory Bowel Disease treated with infliximab Kennedy, N. A.; Goodhand, J.; Bewshea, C.; Nice, R.; Chee, D.; Lin, S.; Chanchlani, N.; Butterworth, J.; Cooney, R.; Croft, N.; Hart, A.; Irving, P.; Kok, K.; Lamb, C.; Limdi, J.; MacDonald, J.; McGovern, D.; Mehta, S.; Murray, C.; Patel, K.; Pollok, R.; Raine, T.; Russell, R.; Selinger, C.; Smith, P.; Bowden, J.; McDonald, T.; Lees, C.; Sebastian, S.; Powell, N.; Ahmad, I. 分享 收藏
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Quality improvement project identifies factors associated with delay in IBD diagnosis Walker, Gareth J.; Lin, Simeng; Chanchlani, Neil; Thomas, Amanda; Hendy, Peter; Heerasing, Neel; Moore, Lucy; Green, Harry D.; Chee, Desmond; Bewshea, Claire; Mays, Joseph; Kennedy, Nicholas A.; Ahmad, Tariq; Goodhand, James R. 分享 收藏
HLA-DQA1*05 Carriage Associated With Development of Anti-Drug Antibodies to Infliximab and Adalimumab in Patients With Crohn's Disease Sazonovs, Aleksejs; Kennedy, Nicholas A.; Moutsianas, Loukas; Heap, Graham A.; Rice, Daniel L.; Reppell, Mark; Bewshea, Claire M.; Chanchlani, Neil; Walker, Gareth J.; Perry, Mandy H.; McDonald, Timothy J.; Lees, Charlie W.; Cummings, J. R. Fraser; Parkes, Miles; Mansfield, John C.; Irving, Peter M.; Barrett, Jeffrey C.; McGovern, Dermot; Goodhand, James R.; Anderson, Carl A.; Ahmad, Tariq 分享 收藏
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