Douglas E. Raines - Publications, H-index & Citations

Douglas E. Raines

Harvard University

35H指数

166论文数

3.2K被引数

收录论文 53

发表时间

Competitive Interactions Between Propofol and Diazepam: Studies in GABAA Receptors and Zebrafish

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2022-12-01

OAAI

Pence, Andrea; Hoyt, Helen; McGrath, Megan; Forman, Stuart A.; Raines, Douglas E.

Pharmacological management of severe Cushing's syndrome: the role of etomidate

THERAPEUTIC ADVANCES IN ENDOCRINOLOGY AND METABOLISM

IF4.6

2022-02-14

OAAI

Pence, Andrea; McGrath, Megan; Lee, Stephanie L.; Raines, Douglas E.

Selective actions of benzodiazepines at the transmembrane anaesthetic binding sites of the GABAA receptor: In vitro and in vivo studies

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2021-09-26

OAAI

McGrath, Megan; Hoyt, Helen; Pence, Andrea; Forman, Stuart A.; Raines, Douglas E.

Competitive Antagonism of Etomidate Action by Diazepam In Vitro GABAA Receptor and In Vivo Zebrafish Studies

ANESTHESIOLOGY

IF9.1

2020-06-10

OAAI

McGrath, Megan; Hoyt, Helen; Pence, Andrea; Jayakar, Selwyn S.; Zhou, Xiaojuan; Forman, Stuart A.; Cohen, Jonathan B.; Miller, Keith W.; Raines, Douglas E.

The effects of a competitive antagonist on GABA-evoked currents in the presence of sedative-hypnotic agents

PHARMACOLOGICAL REPORTS

IF3.8

2020-01-08

OAAI

McGrath, Megan; Tolia, Mansi; Raines, Douglas E.

Computational Approaches to Anesthetic Drug Discovery

TRENDS IN PHARMACOLOGICAL SCIENCES

IF19.9

2019-11-01

PREAI

McGrath, Megan; Pence, Andrea; Raines, Douglas E.

Toxicologic and Inhibitory Receptor Actions of the Etomidate Analog ABP-700 and Its Metabolite CPM-Acid

ANESTHESIOLOGY

IF9.1

2019-08-01

OAAI

Valk, Beatrijs I.; McGrath, Megan; Lehoux, Dario; Zerler, Brad; Marota, John J. A.; Raines, Douglas E.

Etomidate and Etomidate Analog Binding and Positive Modulation of γ-Aminobutyric Acid Type A Receptors Evidence for a State-dependent Cutoff Effect

ANESTHESIOLOGY

IF9.1

2018-11-01

OAAI

McGrath, Megan; Yu, Zhiyi; Jayakar, Selwyn S.; Ma, Celena; Tolia, Mansi; Zhou, Xiaojuan; Miller, Keith W.; Cohen, Jonathan B.; Raines, Douglas E.

Dimethoxy-etomidate: A Nonhypnotic Etomidate Analog that Potently Inhibits Steroidogenesis

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2018-02-01

OAAI

McGrath, Megan; Ma, Celena; Raines, Douglas E.

Competitive Antagonism of Anesthetic Action at the γ-Aminobutyric Acid Type A Receptor by a Novel Etomidate Analog with Low Intrinsic Efficacy

ANESTHESIOLOGY

IF9.1

2017-11-01

OAAI

Ma, Celena; Pejo, Ervin; McGrath, Megan; Jayakar, Selwyn S.; Zhou, Xiaojuan; Miller, Keith W.; Cohen, Jonathan B.; Raines, Douglas E.

Flumazenil Modulation of the γ-Aminobutyric Acid Type A Receptor: Competitive versus Noncompetitive Antagonism at the Agonist-binding Site

ANESTHESIOLOGY

IF9.1

2017-02-01

PREAI

Raines, Douglas E.

Sedative-hypnotic Binding to 11β-hydroxylase

ANESTHESIOLOGY

IF9.1

2016-11-01

OAAI

Pejo, Ervin; Zhou, Xiaojuan; Husain, S. Shaukat; Raines, Douglas E.

γ-Aminobutyric Acid Type A Receptor Modulation by Etomidate Analogs

ANESTHESIOLOGY

IF9.1

2016-03-01

OAAI

Pejo, Ervin; Santer, Peter; Wang, Lei; Dershwitz, Philip; Husain, S. Shaukat; Raines, Douglas E.

Cyclopropyl-methoxycarbonyl Metomidate Studies in a Lipopolysaccharide Inflammatory Model of Sepsis

ANESTHESIOLOGY

IF9.1

2015-08-01

PREAI

Santer, Peter; Pejo, Ervin; Feng, Yan; Chao, Wei; Raines, Douglas E.

Advancing Novel Anesthetics Pharmacodynamic and Pharmacokinetic Studies of Cyclopropyl-methoxycarbonyl Metomidate in Dogs

ANESTHESIOLOGY

IF9.1

2014-12-01

OAAI

Campagna, Jason A.; Pojasek, Kevin; Grayzel, David; Randle, John; Raines, Douglas E.

Analogues of Etomidate Modifications around Etomidate's Chiral Carbon and the Impact on In Vitro and In Vivo Pharmacology

ANESTHESIOLOGY

IF9.1

2014-08-01

OAAI

Pejo, Ervin; Santer, Peter; Jeffrey, Spencer; Gallin, Hilary; Husain, S. Shaukat; Raines, Douglas E.

Adrenocortical suppression and recovery after continuous hypnotic infusion: etomidate versus its soft analogue cyclopropyl-methoxycarbonyl metomidate

CRITICAL CARE

IF9.3

2013-01-30

OAAI

Ge, Rile; Pejo, Ervin; Cotten, Joseph F.; Raines, Douglas E.

Electroencephalographic and Hypnotic Recoveries after Brief and Prolonged Infusions of Etomidate and Optimized Soft Etomidate Analogs

ANESTHESIOLOGY

IF9.1

2012-11-01

OAAI

Ge, Rile; Pejo, Ervin; Husain, S. Shaukat; Cotten, Joseph F.; Raines, Douglas E.

Modifying Methoxycarbonyl Etomidate Inter-Ester Spacer Optimizes In Vitro Metabolic Stability and In Vivo Hypnotic Potency and Duration of Action

ANESTHESIOLOGY

IF9.1

2012-11-01

OAAI

Husain, S. Shaukat; Pejo, Ervin; Ge, Rile; Raines, Douglas E.

Azo-Propofols: Photochromic Potentiators of GABAA Receptors

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2012-09-11

OAAI

Stein, Marco; Middendorp, Simon I.; Carta, Valentina; Pejo, Ervin; Raines, Douglas E.; Forman, Stuart A.; Sigel, Erwin; Trauner, Dirk

研究方向