Kelly L. Bolton - Publications, H-index & Citations

Kelly L. Bolton

Washington University School of Medicine

36H指数

317论文数

6.8K被引数

收录论文 60

发表时间

Germline homologous recombination deficiency influences TP53-mutant clonal hematopoiesis fitness during platinum and PARP inhibitor treatment 生殖系同源重组缺陷影响铂类和PARP抑制剂治疗期间TP53突变克隆性造血的适应性

Nature Genetics

IF29

2026-09-28

OAAI

Jeremy T. Baeten; Irenaeus C. C. Chan; Lea Moukarzel; Giulia E. M. Petrone; Jie Liu; Duc Tran; Jacob Tabs; Imene Tabet; Sumedha Agashe; Elaheh Nasrollahzadeh; Ankush Vasireddy; Amber Carter; Minal Patel; Konrad H. Stopsack; Philip W. Kantoff; Weiyin Zhou; Armel L. Batchi-Bouyou; J. Scott Beeler; Griffen Mustion; Paul Pharoah; James Brenton; Kenneth Offit; Ethan Barnett; Bob Li; Wassim Abida; Alison M. Schram; Britta Weigelt; David Mutch; Alessandro Vindigni; Mary Mullen; Carlos Cruchaga; Howard Scher; Ross Levine; Elli Papaemmanuil; Mitchell J. Machiela; Karen Cadoo; Daniel C. Link; Kelly L. Bolton

Co-occurring clonal hematopoiesis exhibits strong selection and high leukemia risk 同时发生的克隆造血具有很强的选择性和高的白血病风险

Nature Communications

IF15.7

2026-05-21

OAAI

Kara M. Barnao; Aubrey K. Hubbard; Irenaeus C. C. Chan; Weiyin Zhou; Yasminka A. Jakubek; Giulio Genovese; Wendy S. W. Wong; Rebecca L. Kelly; Corey D. Young; Derek W. Brown; Wen-Yi Huang; Neal D. Freedman; Kristine Jones; Amy Hutchinson; Belynda Hicks; Duc Tran; Donna Arnett; Kathleen C. Barnes; Joshua C. Bis; Eric Boerwinkle; Jennifer A. Brody; April P. Carson; Daniel I. Chasman; Michael H. Cho; Pinkal Desai; Margaret F. Doyle; Myriam Fornage; Xiuqing Guo; Nancy Heard-Costa; Marguerite Ryan Irvin; Andrew D. Johnson; Sharon L. R. Kardia; Charles Kooperberg; Daniel Levy; Joshua P. Lewis; Yun Li; Ruth J. F. Loos; Taralynn M. Mack; Rasika A. Mathias; Braxton D. Mitchell; Kari E. North; Nathan Pankratz; Patricia A. Peyser; Michael H. Preuss; Bruce M. Psaty; Laura M. Raffield; Susan Redline; Stephen S. Rich; Jerome I. Rotter; Edwin K. Silverman; Albert V. Smith; Jennifer A. Smith; Adrienne Stilp; Yin Cao; Paul Scheet; Alexander P. Reiner; Alexander G. Bick; Stephen J. Chanock; Paul L. Auer; Kelly L. Bolton; Mitchell J. Machiela

CDK4/6 inhibition mitigates chemotherapy-induced expansion of TP53-mutant clonal hematopoiesis CDK4/6抑制减轻化疗诱导的TP53-mutant克隆造血功能的扩增

Nature Genetics

IF29

2026-03-11

OAAI

Irenaeus C. C. Chan; Pu Zhang; Xiangyu Pan; Cynthia Castro; Nina Fox; Alexander M. Lewis; Kenyon Weis; Adriana Cuibus; Steven Tittley; Giulia Petrone; J. Scott Beeler; Duc Tran; Griffen Mustion; Catrina Fronick; Konrad H. Stopsack; Carlos Cruchaga; Omar Abdel-Wahab; Kelly L. Bolton

Impact of Exercise on Clonal Hematopoiesis

JACC-ADVANCES

IF0

2025-10-01

OAAI

Scott, Jessica M.; Tsai, Brandon L.; Stewart, Caitlin; Eng, Stefan E.; White, James R.; Bolton, Kelly L.; Vaz-Luis, Ines; Havas, Julie; Di Meglio, Antonio; Martin, Anne-Laure; Boyault, Sandrine; Wang, Ruilin; Micol, Jean Baptiste; Diaz, Luis A.; Boutros, Paul C.; Jones, Lee W.

Risk of clonal hematopoiesis in families exposed to radiation following the Chornobyl accident 切尔诺贝利事故后受辐射影响的家庭的克隆性造血风险

CARCINOGENESIS

IF2.9

2025-09-01

OAAI

Machiela, Mitchell J.; Wong, Wendy S. W.; Mai, Jim Z.; Karyadi, Danielle M.; Drozdovitch, Vladimir; Chan, Irenaeus; Vij, Vibha; Zhou, Weiyin; Luo, Wen; Wu, Dongjing; Hutchinson, Amy; Jones, Kristine; Hicks, Belynda; Bakhanova, Elena; Chumak, Vadim; Gudzenko, Natalia; Kryuchkov, Victor; Golovanov, Ivan; Bolton, Kelly; Cahoon, Elizabeth K.; Morton, Lindsay M.; Bazyka, Dimitry; Chanock, Stephen J.

Impact of radiotherapy site, modality, and dose on subsequent clonal hematopoiesis 放射治疗部位、模式和剂量对后续克隆性造血的影响

Blood Advances

IF7.1

2025-08-14

OAAI

Alexander G. Goglia; Griffen R. Mustion; Leslie A. Modlin; Ross L. Levine; Kelly L. Bolton; Lior Z. Braunstein

Germline genetic variation impacts clonal hematopoiesis landscape and progression to malignancy 种系遗传变异影响克隆造血景观和发展为恶性肿瘤

Nature Genetics

IF0

2025-07-15

OAAI

Jie Liu; Duc Tran; Liying Xue; Brian J. Wiley; Caitlyn Vlasschaert; Caroline J. Watson; Hamish A. J. MacGregor; Xiaoyu Zong; Irenaeus C. C. Chan; Indraniel Das; Md Mesbah Uddin; Abhishek Niroula; Gabriel Griffin; Benjamin L. Ebert; Taralynn Mack; Yash Pershad; Brian Sharber; Michael Berger; Ahmet Zehir; Ryan Ptashkin; Ross L. Levine; Elli Papaemmanuil; Vijai Joseph; Teng Gao; Yelena Kemel; Diana Mandelker; Konrad H. Stopsack; Paul D. P. Pharoah; Semanti Mukherjee; Li Ding; Yin Cao; Matthew J. Walter; Jamie R. Blundell; Nilanjan Chatterjee; Kenneth Offit; Lucy A. Godley; Daniel C. Link; Zsofia K. Stadler; Alexander G. Bick; Pradeep Natarajan; Kelly L. Bolton

Deconvoluting clonal and cellular architecture in IDH-mutant acute myeloid leukemia 解构IDH突变急性髓系白血病中的克隆和细胞架构

Cell Stem Cell

IF20.4

2025-05-22

PREAI

Maria Sirenko; Soobeom Lee; Zhengxi Sun; Ronan Chaligne; Sanam Loghavi; Georgios Asimomitis; Charlotte K. Brierley; Elsa Bernard; Sheng F. Cai; Robert M. Myers; Bettina Nadorp; Junya Sango; Morgan Lallo; Max F. Levine; Dylan Domenico; Juan E. Arango Ossa; Juan S. Medina-Martinez; Kamal Menghrajani; Audrey Lasry; Alice S. Mims; Helee Desai; Andrea Laganson; Chris Famulare; Minal Patel; Gerard Lozanski; Kelly L. Bolton; Aaron D. Viny; Mikhail Roshal; Ross L. Levine; Eirini P. Papapetrou; Eytan M. Stein; Dan A. Landau; Ann-Kathrin Eisfeld; Iannis Aifantis; Elli Papaemmanuil

Impact of cancer therapy on clonal hematopoiesis mutations and subsequent clinical outcomes

BLOOD ADVANCES

IF7.1

2024-10-08

OAAI

Nead, Kevin T.; Kim, Taebeom; Joo, Lijin; Mcdowell, Tina L.; Wong, Justin W.; Chan, Irenaeus C. C.; Brock, Elizabeth; Zhao, Jing; Xu, Ting; Tang, Chad; Lee, Chang-Lung; Abe, Jun-ichi; Bolton, Kelly L.; Liao, Zhongxing; Scheet, Paul A.; Lin, Steven H.

Social, behavioral and clinical risk factors are associated with clonal hematopoiesis

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

IF3.4

2024-09-21

PREAI

Young, Corey D.; Hubbard, Aubrey K.; Saint-Maurice, Pedro; Chan, Irenaeus; Bolton, Kelly L.; Chanock, Stephen J.; Matthews, Charles; Moore, Steven C.; Loftfield, Erikka; Machiela, Mitchell J.

Social, Behavioral, and Clinical Risk Factors Are Associated with Clonal Hematopoiesis 社会、行为和临床危险因素与克隆造血相关

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

IF3.4

2024-08-29

PREAI

Young, Corey D.; Hubbard, Aubrey K.; Saint-Maurice, Pedro F.; Chan, Irenaeus C. C.; Cao, Yin; Tran, Duc; Bolton, Kelly L.; Chanock, Stephen J.; Matthews, Charles E.; Moore, Steven C.; Loftfield, Erikka; Machiela, Mitchell J.

Clinical and Therapeutic Implications of Clonal Hematopoiesis 克隆性造血的临床和治疗意义

annual review of genetics

IF7.9

2024-08-27

OAAI

Petrone, Giulia; Turker, Isik; Natarajan, Pradeep; Bolton, Kelly L.

Unraveling facets of MECOM-associated syndrome: somatic genetic rescue, clonal hematopoiesis, and phenotype expansion

BLOOD ADVANCES

IF7.1

2024-06-27

PREAI

Venugopal, Parvathy; Arts, Peer; Fox, Lucy C.; Simons, Annet; Hiwase, Devendra K.; Bardy, Peter G.; Swift, Annette; Ross, David M.; van Vulpen, Lize F. D.; Buijs, Arjan; Bolton, Kelly L.; Getta, Bartlomiej; Furlong, Eliska; Carter, Tina; Krapels, Ingrid; Hoeks, Marlijn; Al Kindy, Adila; Al Kindy, Farah; de Munnik, Sonja; Evans, Pamela; Frank, Mahalia S. B.; Bournazos, Adam M.; Cooper, Sandra T.; Ha, Thuong Thi; Jackson, Matilda R.; Arriola-Martinez, Luis; Phillips, Kerry; Brennan, Yvonne; Bakshi, Madhura; Ambler, Karen; Gao, Song; Kassahn, Karin S.; Kenyon, Rosalie; Hung, Kevin; Babic, Milena; Mcgovern, Alan; Rawlings, Lesley; Vakulin, Cassandra; Dejong, Lucas; Fathi, Rema; Mcrae, Simon; Myles, Nicholas; Ladon, Dariusz; Jongmans, Marjolijn; Kuiper, Roland P.; Poplawski, Nicola K.; Barbaro, Pasquale; Blombery, Piers; Brown, Anna L.; Hahn, Christopher N.; Scott, Hamish S.

Integrative multi-omics analyses to identify the genetic and functional mechanisms underlying ovarian cancer risk regions 整合多组学分析以确定卵巢癌风险区域的遗传和功能机制

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2024-06-01

PREAI

Dareng, Eileen O.; Coetzee, Simon G.; Tyrer, Jonathan P.; Peng, Pei-Chen; Rosenow, Will; Chen, Stephanie; Davis, Brian D.; Dezem, Felipe Segato; Seo, Ji-Heui; Nameki, Robbin; Reyes, Alberto L.; Aben, Katja K. H.; Anton-Culver, Hoda; Antonenkova, Natalia N.; Aravantinos, Gerasimos; Bandera, Elisa V.; Freeman, Laura E. Beane; Beckmann, Matthias W.; Beeghly-Fadiel, Alicia; Benitez, Javier; Bernardini, Marcus Q.; Bjorge, Line; Black, Amanda; Bogdanova, Natalia V.; Bolton, Kelly L.; Brenton, James D.; Budzilowska, Agnieszka; Butzow, Ralf; Cai, Hui; Campbell, Ian; Cannioto, Rikki; Chang-Claude, Jenny; Chanock, Stephen J.; Chen, Kexin; Chenevix-Trench, Georgia; Chiew, Yoke-Eng; Cook, Linda S.; DeFazio, Anna; Dennis, Joe; Doherty, Jennifer A.; Doerk, Thilo; du Bois, Andreas; Duerst, Matthias; Eccles, Diana M.; Ene, Gabrielle; Fasching, Peter A.; Flanagan, James M.; Fortner, Renee T.; Fostira, Florentia; Gentry-Maharaj, Aleksandra; Giles, Graham G.; Goodman, Marc T.; Gronwald, Jacek; Haiman, Christopher A.; Hakansson, Niclas; Heitz, Florian; Hildebrandt, Michelle A. T.; Hogdall, Estrid; Hogdall, Claus K.; Huang, Ruea-Yea; Jensen, Allan; Jones, Michael E.; Kang, Daehee; Karlan, Beth Y.; Karnezis, Anthony N.; Kelemen, Linda E.; Kennedy, Catherine J.; Khusnutdinova, Elza K.; Kiemeney, Lambertus A.; Kjaer, Susanne K.; Kupryjanczyk, Jolanta; Labrie, Marilyne; Lambrechts, Diether; Larson, Melissa C.; Le, Nhu D.; Lester, Jenny; Li, Lian; Lubinski, Jan; Lush, Michael; Marks, Jeffrey R.; Matsuo, Keitaro; May, Taymaa; McLaughlin, John R.; McNeish, Iain A.; Menon, Usha; Missmer, Stacey; Modugno, Francesmary; Moffitt, Melissa; Monteiro, Alvaro N.; Moysich, Kirsten B.; Narod, Steven A.; Nguyen-Dumont, Tu; Odunsi, Kunle; Olsson, Hakan; Onland-Moret, N. Charlotte; Park, Sue K.; Pejovic, Tanja; Permuth, Jennifer B.; Piskorz, Anna; Prokofyeva, Darya; Riggan, Marjorie J.; Risch, Harvey A.; Rodriguez-Antona, Cristina; Rossing, Mary Anne; Sandler, Dale P.; Setiawan, V. Wendy; Shan, Kang; Song, Honglin; Southey, Melissa C.; Steed, Helen; Sutphen, Rebecca; Swerdlow, Anthony J.; Teo, Soo Hwang; Terry, Kathryn L.; Thompson, Pamela J.; Thomsen, Liv Cecilie Vestrheim; Titus, Linda; Trabert, Britton; Travis, Ruth; Tworoger, Shelley S.; Valen, Ellen; Van Nieuwenhuysen, Els; Edwards, Digna Velez; Vierkant, Robert A.; Webb, Penelope M.; Weinberg, Clarice R.; Weise, Rayna Matsuno; Wentzensen, Nicolas; White, Emily; Winham, Stacey J.; Wolk, Alicja; Woo, Yin-Ling; Wu, Anna H.; Yan, Li; Yannoukakos, Drakoulis; Zeinomar, Nur; Zheng, Wei; Ziogas, Argyrios; Berchuck, Andrew; Goode, Ellen L.; Huntsman, David G.; Pearce, Celeste L.; Ramus, Susan J.; Sellers, Thomas A.; Freedman, Matthew L.; Lawrenson, Kate; Schildkraut, Joellen M.; Hazelett, Dennis; Plummer, Jasmine T.; Kar, Siddhartha; Jones, Michelle R.; Pharoah, Paul D. P.; Gayther, Simon A.

A novel method for rapid estimation of active bone marrow dose for radiotherapy patients in epidemiological studies 在流行病学研究中快速估算放射治疗患者有效骨髓剂量的新方法

MEDICAL PHYSICS

IF3.2

2024-05-12

OAAI

Yeom, Yeon Soo; Braunstein, Lior; Morton, Lindsay M.; Bolton, Kelly L.; Choi, Ji Won; Choi, Hyeong Yun; Greenstein, Natasha; Lee, Choonsik

NRG-BR008: A Phase III Randomized Trial of Radiotherapy Optimization for Lowrisk HER2-positive Breast Cancer (HERO)

CANCER RESEARCH

IF16.6

2024-05-02

PREAI

Braunstein, Lior; Mitchell, Melissa; Bandos, Hanna; Sikov, William; Khan, Atif; Chen, Peter; Ganz, Patricia; Jagsi, Reshma; White, Julia; Cecchini, Reena; Kang, Hyejoo; Puhalla, Shannon; Bolton, Kelly; Connolly, Eileen; Stringer-Reasor, Erica; Gergelis, Kimberly; Julian, Thomas; Mamounas, Eleftherios; Wolmark, Norman

Genome and clonal hematopoiesis stability contrasts with immune, cfDNA, mitochondrial, and telomere length changes during short duration spaceflight

PRECISION CLINICAL MEDICINE

IF5

2024-04-08

OAAI

Garcia-Medina, J. Sebastian; Sienkiewicz, Karolina; Narayanan, S. Anand; Overbey, Eliah G.; Grigorev, Kirill; Ryon, Krista A.; Burke, Marissa; Proszynski, Jacqueline; Tierney, Braden; Schmidt, Caleb M.; Mencia-Trinchant, Nuria; Klotz, Remi; Ortiz, Veronica; Foox, Jonathan; Chin, Christopher; Najjar, Deena; Matei, Irina; Chan, Irenaeus; Cruchaga, Carlos; Kleinman, Ashley; Kim, Jangkeun; Lucaci, Alexander; Loy, Conor; Mzava, Omary; De Vlaminck, Iwijn; Singaraju, Anvita; Taylor, Lynn E.; Schmidt, Julian C.; Schmidt, Michael A.; Blease, Kelly; Moreno, Juan; Boddicker, Andrew; Zhao, Junhua; Lajoie, Bryan; Altomare, Andrew; Kruglyak, Semyon; Levy, Shawn; Yu, Min; Hassane, Duane C.; Bailey, Susan M.; Bolton, Kelly; Mateus, Jaime; Mason, Christopher E.

Modifiable risk factors are associated with clonal hematopoiesis

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Young, Corey D.; Hubbard, Aubrey K.; Saint-Maurice, Pedro; Chan, Irenaeus; Bolton, Kelly L.; Chanock, Stephen J.; Matthews, Charles; Moore, Steven C.; Loftfield, Erikka; Cao, Yin; Machiela, Mitchell J.; Duc Tran

Characterization of co-occurring clonal hematopoiesis to identify high risk clones associated with hematologic cancer risk

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Barnao, Kara M.; Hubbard, Aubrey K.; Zhou, Weiyin; Chan, Irenaeus; Duc Tran; Cao, Yin; Chanock, Stephen J.; Bolton, Kelly L.; Machiela, Mitchell J.

Donor-Derived Malignancy and Transplantation Morbidity: Risks of Patient and Donor Genetics in Allogeneic Hematopoietic Stem Cell Transplantation 供者来源的恶性肿瘤和移植发病率: 异基因造血干细胞移植中患者和供者遗传学的风险

TRANSPLANTATION AND CELLULAR THERAPY

IF4.4

2024-03-01

PREAI

Williams, Lacey S.; Williams, Kirsten M.; Gillis, Nancy; Bolton, Kelly; Damm, Frederik; Deuitch, Natalie T.; Farhadfar, Nosha; Gergis, Usama; Keel, Sioban B.; Michelis, Fotios, V; Panch, Sandhya R.; Porter, Christopher C.; Sucheston-Campbell, Lara; Tamari, Roni; Stefanski, Heather E.; Godley, Lucy A.; Lai, Catherine

研究方向