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Genealogy-based trait association with LOCATER boosts power at loci with allelic heterogeneity 基于系谱的性状关联结合LOCATER在等位基因异质性位点提高统计功效 Wang, Xinxin; Christ, Ryan; Young, Erica; Kang, Chul Joo; Das, Indraniel; Belter Jr, Edward A.; Laakso, Markku; Aslett, Louis J. M.; Steinsaltz, David; Stitziel, Nathan O.; Hall, Ira M. 分享 收藏
Comparison of variant callers using 60 532 multi-ancestry whole genome sequences 比较不同变异调用器在60532例多祖先全基因组序列中的应用 Zhou, Hufeng; Li, Zilin; Shyr, Derek; Li, Xihao; Yang, Haoyu; Dey, Rounak; Tang, Yushi; Maier, Robert; Boerwinkle, Eric; Buyske, Steve; Daly, Mark; Felsenfeld, Adam; Gibbs, Richard A.; Gupta, Namrata; Hall, Ira M.; Matise, Tara; Metcalf, Ginger A.; Smith, Albert; Reeves, Catherine; Sofia, Heidi J.; Stitziel, Nathan O.; Zody, Michael C.; Neale, Benjamin; Lin, Xihong 分享 收藏
Targeting modulated vascular smooth muscle cells in atherosclerosis via FAP-directed immunotherapy Amrute, J.M.; Jung, I.H.; Yamawaki, T.; Lin, W.L.; Bredemeyer, A.; Diekmann, J.; Hayat, S.; Zhang, X.; Wakefield, D.L.; Luo, X.; et al. 通过FAP定向免疫疗法靶向调节动脉粥样硬化中的血管平滑肌细胞。Science 2026, eadx1736. [Google Scholar] [CrossRef] Junedh M. Amrute; In-Hyuk Jung; Tracy Yamawaki; Wen-Ling Lin; Andrea Bredemeyer; Johanna Diekmann; Sikander Hayat; Xianglong Zhang; Devin L. Wakefield; Xin Luo; Sidrah Maryam; Gyu Seong Heo; Steven Yang; Chang Jie Mick Lee; Chen Wang; Caroline Chou; Christoph Kuppe; Kevin D. Cook; Atilla Kovacs; Vishnu Chintalgattu; Danielle Pruitt; Jose Barreda; Nathan O. Stitziel; Paul Cheng; Yongjian Liu; Rafael Kramann; Daniel Kreisel; Roger S.-Y. Foo; Ingrid C. Rulifson; Scott Martin; David Grunert; Melissa Thomas; Jixin Cui; Thomas Quertermous; Frank M. Bengel; Simon Jackson; Chi-Ming Li; Brandon Ason; Kory J. Lavine 分享 收藏
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Unveiling the Genetic Landscape of Coronary Artery Disease Through Common and Rare Structural Variants 通过常见和罕见的结构变异揭示冠状动脉疾病的遗传景观 Iyer, Kruthika R.; Clarke, Shoa L.; Guarischi-Sousa, Rodrigo; Gjoni, Ketrin; Heath, Adam S.; Young, Erica P.; Stitziel, Nathan O.; Laurie, Cecelia; Broome, Jai G.; Khan, Alyna T.; Lewis, Joshua P.; Xu, Huichun; Montasser, May E.; Ashley, Kellan E.; Hasbani, Natalie R.; Boerwinkle, Eric; Morrison, Alanna C.; Chami, Nathalie; Do, Ron; Rocheleau, Ghislain; Lloyd-Jones, Donald M.; Lemaitre, Rozenn N.; Bis, Joshua C.; Floyd, James S.; Kinney, Gregory L.; Bowden, Donald W.; Palmer, Nicholette D.; Benjamin, Emelia J.; Nayor, Matthew; Yanek, Lisa R.; Kral, Brian G.; Becker, Lewis C.; Kardia, Sharon L. R.; Smith, Jennifer A.; Bielak, Lawrence F.; Norwood, Arnita F.; Min, Yuan-I; Carson, April P.; Post, Wendy S.; Rich, Stephen S.; Herrington, David; Guo, Xiuqing; Taylor, Kent D.; Manson, JoAnn E.; Franceschini, Nora; Pollard, Katherine S.; Mitchell, Braxton D.; Loos, Ruth J. F.; Fornage, Myriam; Hou, Lifang; Psaty, Bruce M.; Young, Kendra A.; Regan, Elizabeth A.; Freedman, Barry I.; Vasan, Ramachandran S.; Levy, Daniel; Mathias, Rasika A.; Peyser, Patricia A.; Raffield, Laura M.; Kooperberg, Charles; Reiner, Alex P.; Rotter, Jerome I.; Jun, Goo; de Vries, Paul S.; Assimes, Themistocles L. 分享 收藏
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Improving the prediction of major adverse cardiovascular events in patients with hypertrophic cardiomyopathy by adding plasma SVEP1 to conventional clinical model including NT-proBNP Osawa, I; Akita, K.; Hasegawa, K.; Fifer, M. A.; Tower-Rader, A.; Reilly, M. P.; Maurer, M. S.; Stitziel, N. O.; Javaheri, A.; Shimada, Y. J. 分享 收藏
Rare variant contribution to the heritability of coronary artery disease 罕见变异对冠状动脉疾病遗传性的贡献 Rocheleau, Ghislain; Clarke, Shoa L.; Auguste, Gaelle; Hasbani, Natalie R.; Morrison, Alanna C.; Heath, Adam S.; Bielak, Lawrence F.; Iyer, Kruthika R.; Young, Erica P.; Stitziel, Nathan O.; Jun, Goo; Laurie, Cecelia; Broome, Jai G.; Khan, Alyna T.; Arnett, Donna K.; Becker, Lewis C.; Bis, Joshua C.; Boerwinkle, Eric; Bowden, Donald W.; Carson, April P.; Ellinor, Patrick T.; Fornage, Myriam; Franceschini, Nora; Freedman, Barry I.; Heard-Costa, Nancy L.; Hou, Lifang; Chen, Yii-Der Ida; Kenny, Eimear E.; Kooperberg, Charles; Kral, Brian G.; Loos, Ruth J. F.; Lutz, Sharon M.; Manson, JoAnn E.; Martin, Lisa W.; Mitchell, Braxton D.; Nassir, Rami; Palmer, Nicholette D.; Post, Wendy S.; Preuss, Michael H.; Psaty, Bruce M.; Raffield, Laura M.; Regan, Elizabeth A.; Rich, Stephen S.; Smith, Jennifer A.; Taylor, Kent D.; Yanek, Lisa R.; Young, Kendra A.; Anugu, Pramod; Arnett, Donna K.; Assimes, Themistocles L.; Auer, Paul; Barwick, Lucas; Becker, Diane; Becker, Lewis C.; Bielak, Lawrence F.; Bis, Joshua C.; Boerwinkle, Eric; Bowden, Donald W.; Broome, Jai G.; Carson, April P.; Carty, Cara; Castaldi, Peter; Chaffin, Mark; Chang, Yi-Cheng; Choi, Seung Hoan; Chung, Ren-Hua; Clarke, Shoa L.; Crandall, Carolyn; David, Sean; de las Fuentes, Lisa; Deka, Ranjan; DeMeo, Dawn; de Vries, Paul S.; Do, Ron; Duan, Qing; Eaton, Charles; Ekunwe, Lynette; El Boueiz, Adel; Ellinor, Patrick T.; Fornage, Myriam; Franceschini, Nora; Freedman, Barry I.; Gao, Shanshan; Gao, Yan; Gass, Margery; Ghosh, Auyon; Grine, Daniel; Hall, Michael; Hasbani, Natalie R.; Heard-Costa, Nancy L.; Heath, Adam S.; Hersh, Craig; Hobbs, Brian; Hou, Lifang; Hsiung, Chao Agnes; Hung, Yi-Jen; Huston, Haley; Hwu, Chii Min; Chen, Yii-Der Ida; Iyer, Kruthika R.; Jackson, Rebecca; Johnsen, Jill; Jun, Goo; Kenny, Eimear E.; Khan, Alyna T.; Kooperberg, Charles; Kral, Brian G.; Lange, Christoph; Lange, Ethan; Laurie, Cecelia; LeBoff, Meryl; Lee, Wen-Jane; Li, Yun; Liu, Simin; Liu, Yu; Loos, Ruth J. F.; Lutz, Sharon M.; Manson, JoAnn E.; Martin, Lisa W.; Mathai, Susan; Mei, Hao; Miller, Clint L.; Mitchell, Braxton D.; Morrison, Alanna C.; Naik, Rakhi; Naseri, Take; Nassir, Rami; Neltner, Bonnie; Ochs-Balcom, Heather; Paik, David T.; Palmer, Nicholette D.; Parker, Cora; Perez, Marco; Peters, Ulrike; Peyser, Patricia A.; Phillips, Lawrence S.; Post, Wendy S.; Becker, Julia Powers; Preuss, Michael H.; Psaty, Bruce M.; Raffield, Laura M.; Regan, Elizabeth A.; Reupena, Muagututi'a Sefulva; Rich, Stephen S.; Rocheleau, Ghislain; Roselli, Carolina; Rotter, Jerome I.; Russell, Pamela; Sabino, Ester Cerdeira; Sandow, Kevin; Schwander, Karen; Sciurba, Frank; Silver, Brian; Smith, Jennifer A.; Smoller, Sylvia; Snively, Beverly; Stitziel, Nathan O.; Storm, Garrett; Sung, Yun Ju; Tang, Hua; Taub, Margaret; Taylor, Kent D.; Tinker, Lesley; Tirschwell, David; Tiwari, Hemant; Vaidya, Dhananjay; Vasan, Ramachandran S.; Walker, Tarik; Wallace, Robert; Walts, Avram; Weng, Lu-Chen; Yanek, Lisa R.; Yang, Ivana; Young, Erica P.; Young, Kendra A.; Zhao, Snow Xueyan; Hilliard, Austin T.; Tcheandjieu, Catherine; Peyser, Patricia A.; Vasan, Ramachandran S.; Rotte, Jerome I.; Miller, Clint L.; Assimes, Themistocles L.; de Vries, Paul S.; Do, Ron 分享 收藏
Semi-supervised machine learning method for predicting homogeneous ancestry groups to assess Hardy-Weinberg equilibrium in diverse whole-genome sequencing studies Shyr, Derek; Dey, Rounak; Li, Xihao; Zhou, Hufeng; Boerwinkle, Eric; Buyske, Steve; Daly, Mark; Gibbs, Richard A.; Hall, Ira; Matise, Tara; Reeves, Catherine; Stitziel, Nathan O.; Zody, Michael; Neale, Benjamin M.; Lin, Xihong 分享 收藏
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Single Cell Transcriptional And Epigenetic Map Of Human Coronary Artery Disease In A Multi-ethnic Population Amrute, Junedh M.; Lee, Paul; Eres, Ittai; Bredemeyer, Andrea; Yamawaki, Tracy; Kang, Chul Joo; Lee, Mick J.; Gurung, Rijan; Li, Daniel; Zhao, Quanyi; Sheth, Maya; Tan, Anthony; Gschwind, Andreas; Cheng, Paul; Jackson, Simon; Hsu, Yi-Hsiang; Foo, Roger; Hall, Ira; Gupta, Rajat M.; Engreitz, Jesse; Li, Chi-Ming; Quertermous, Thomas; Ason, Brandon; Lavine, Kory J.; Stitziel, Nathan O. 分享 收藏
LRRC8 Complex Is An ATP Release Channel Regulating Platelet Activation And Thrombosis Tranter, John D.; Kumar, Ashutosh; Brown, Gavriel; Mikami, Ryan; Zhao, Yonghui; Abraham, Nihil; Abd El-Aziz, Tarek M.; Ajanel, Abigail; Xie, Litao; Ashworth, Katrina; Hong, Juan; Zhang, Haixia; Kumari, Tripti; Liu, Alice; Balutowski, Adam; Nair, Vinayak K.; Lasky, Nina M.; Feng, Yongmei; Stitziel, Nathan O.; Lerner, Daniel J.; Campbell, Robert A.; Di Paola, Jorge; Cho, Jaehyung; Sah, Rajan 分享 收藏
Identification of a leucine-mediated threshold effect governing macrophage mTOR signalling and cardiovascular risk Zhang, Xiangyu; Kapoor, Divya; Jeong, Se-Jin; Fappi, Alan; Stitham, Jeremiah; Shabrish, Vasavi; Sergin, Ismail; Yousif, Eman; Rodriguez-Velez, Astrid; Yeh, Yu-Sheng; Park, Arick; Yurdagul, Arif, Jr.; Rom, Oren; Epelman, Slava; Schilling, Joel D.; Sardiello, Marco; Diwan, Abhinav; Cho, Jaehyung; Stitziel, Nathan O.; Javaheri, Ali; Lodhi, Irfan J.; Mittendorfer, Bettina; Razani, Babak 分享 收藏
ANGPTL3 deficiency impairs lipoprotein production and produces adaptive changes in hepatic lipid metabolism Burks, Kendall H.; Xie, Yan; Gildea, Michael; Jung, In-Hyuk; Mukherjee, Sandip; Lee, Paul; Pudupakkam, Upasana; Wagoner, Ryan; Patel, Ved; Santana, Katherine; Alisio, Arturo; Goldberg, Ira J.; Finck, Brian N.; Fisher, Edward A.; Davidson, Nicholas O.; Stitziel, Nathan O. 分享 收藏
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