John M. Vierling - Publications, H-index & Citations

John M. Vierling

gastro one

66H指数

360论文数

1.9W被引数

收录论文 151

发表时间

Seladelpar in patients with primary biliary cholangitis and compensated cirrhosis: Efficacy and safety from RESPONSE and ASSURE studies 塞拉德尔帕（Seladelpar）在原发性胆汁性胆管炎合并代偿期肝硬化患者中的疗效与安全性：来自RESPONSE和ASSURE研究的数据

Hepatology Communications

IF4.6

2026-05-01

PREAI

Gordon, Stuart C.; Villamil, Alejandra; Jacobson, Ira M.; Lawitz, Eric J.; Younes, Ziad; Silveira, Marina G.; Bowlus, Christopher L.; Drenth, Joost P. H.; Vierling, John M.; Morgera, Ulrike; Vasura, Adam; Dalekos, George; Galli, Andrea; Rabinovitz, Mordechai; Heo, Jeong; Nevens, Frederik; Levy, Cynthia; Zhou, Yan; Carroll, Susheela; Crittenden, Daria B.

Fracture events in patients with primary biliary cholangitis during treatment with seladelpar in the phase III RESPONSE trial 在III期RESPONSE试验中，原发性胆汁性胆管炎患者在服用seladelpar治疗期间发生的骨折事件

Hepatology Communications

IF4.6

2025-11-20

OAAI

Vierling, John M.; Hirschfield, Gideon M.; Kustra, Robert P.; Liu, Xiangyu; Proehl, Sarah; Crittenden, Daria B.

Lessons From COBALT: Will the Bell Also Toll for Thee?从COBALT中汲取的教训：钟声也会为你而鸣吗？

AMERICAN JOURNAL OF GASTROENTEROLOGY

IF7.6

2024-10-02

PREAI

Vierling, JM; Pockros, PJ

Primary biliary cholangitis

LANCET

IF88.5

2024-09-01

OAAI

Tanakai, Atsushi; Mai, Xiong; Takahashi, Atsushi; Vierling, John M.

Metabolomics biomarkers of hepatocellular carcinoma in a prospective cohort of patients with cirrhosis 肝硬化患者前瞻性队列中肝细胞癌的代谢组学生物标志物

JHEP REPORTS

IF7.5

2024-08-01

OAAI

Sanchez, Jessica I.; Fontillas, Antoine C.; Kwan, Suet-Ying; Sanchez, Caren I.; Calderone, Tiffany L.; Lee, Jana L.; Elsaiey, Ahmed; Cleere, Darrel W.; Wei, Peng; Vierling, John M.; Victor, David W.; Beretta, Laura

Immunopathogenesis of Primary Biliary Cholangitis, Primary Sclerosing Cholangitis and Autoimmune Hepatitis: Themes and Concepts

GASTROENTEROLOGY

IF25.1

2024-06-01

PREAI

Trivedi, Palak J.; Hirschfield, Gideon M.; Adams, David H.; Vierling, John M.

A Phase 3 Trial of Seladelpar in Primary Biliary Cholangitis Seladelpar在原发性胆汁性胆管炎中的3期试验

NEW ENGLAND JOURNAL OF MEDICINE

IF78.5

2024-02-29

PREAI

Hirschfield, Gideon M.; Bowlus, Christopher L.; Mayo, Marlyn J.; Kremer, Andreas E.; Vierling, John M.; Kowdley, Kris V.; Levy, Cynthia; Villamil, Alejandra; Cetina, Alma L. Ladron de Guevara; Janczewska, Ewa; Zigmond, Ehud; Jeong, Sook-Hyang; Yilmaz, Yusuf; Kallis, Yiannis; Corpechot, Christophe; Buggisch, Peter; Invernizzi, Pietro; Hurtado, Maria Carlota Londono; Bergheanu, Sandrin; Yang, Ke; Choi, Yun-Jung; Crittenden, Daria B.; McWherter, Charles A.

Efficacy and Safety of Elafibranor in Primary Biliary Cholangitis Elafibranor在原发性胆汁性胆管炎中的疗效和安全性

NEW ENGLAND JOURNAL OF MEDICINE

IF78.5

2024-02-29

PREAI

Kowdley, Kris V.; Bowlus, Christopher L.; Levy, Cynthia; Akarca, Ulus S.; Alvares-da-Silva, Mario Reis; Andreone, Pietro; Arrese, Marco; Corpechot, Christophe; Francque, Sven M.; Heneghan, Michael A.; Invernizzi, Pietro; Jones, David; Kruger, Frederik C.; Lawitz, Eric; Mayo, Marlyn J.; Shiffman, Mitchell L.; Swain, Mark G.; Valera, Jose Miguel; Vargas, Victor; Vierling, John M.; Villamil, Alejandra; Addy, Carol; Dietrich, Julie; Germain, Jean-Michel; Mazain, Sarah; Rafailovic, Dragutin; Tadde, Bachirou; Miller, Benjamin; Shu, Jianfen; Zein, Claudia O.; Schattenberg, Jorn M.

Consensus Guidelines: Best Practices for the Prevention, Detection and Management of Hepatitis B Virus Reactivation in Clinical Trials with Immunosuppressive/Immunomodulatory Therapy

DRUG SAFETY

IF3.8

2024-02-14

OAAI

Cohen, Eric B.; Regev, Arie; Garg, Anju; Di Bisceglie, Adrian M.; Lewis, James H.; Vierling, John M.; Hey-Hadavi, Judith; Steplewski, Klaudia; Fettiplace, Anna; Chen, Chunlin L.; Pehlivanov, Nonko; Kendrick, Stuart; Avigan, Mark, I

Editorial: The evolving paradigms and treatments for primary biliary cholangitis-Authors' reply 社论: 原发性胆汁性胆管炎的发展范式和治疗方法-作者的回复

ALIMENTARY PHARMACOLOGY & THERAPEUTICS

IF6.7

2023-12-28

OAAI

Mayo, Marlyn J.; Vierling, John M.; Bowlus, Christopher L.

Rusfertide for the treatment of iron overload in HFE-related haemochromatosis: an open-label, multicentre, proof-of- concept phase 2 trial

LANCET GASTROENTEROLOGY & HEPATOLOGY

IF38.6

2023-12-01

PREAI

Kowdley, Kris, V; Modi, Nishit B.; Peltekian, Kevork; Vierling, John M.; Ferris, Christopher; Valone, Frank H.; Gupta, Suneel

Open-label, clinical trial extension: Two-year safety and efficacy results of seladelpar in patients with primary biliary cholangitis 开放标签，临床试验扩展: seladelpar在原发性胆汁性胆管炎患者中的两年安全性和有效性结果

ALIMENTARY PHARMACOLOGY & THERAPEUTICS

IF6.7

2023-10-30

OAAI

Mayo, Marlyn J.; Vierling, John M.; Bowlus, Christopher L.; Levy, Cynthia; Hirschfield, Gideon M.; Neff, Guy W.; Galambos, Michael R.; Gordon, Stuart C.; Borg, Brian B.; Harrison, Stephen A.; Thuluvath, Paul J.; Goel, Aparna; Shiffman, Mitchell L.; Swain, Mark G.; Jones, David E. J.; Trivedi, Palak; Kremer, Andreas E.; Aspinall, Richard J.; Sheridan, David A.; Doerffel, Yvonne; Yang, Ke; Choi, Yun-Jung; McWherter, Charles A.

The clinical imperative of a complete biochemical response to immunosuppression in autoimmune hepatitis: Close is not good enough!

HEPATOLOGY

IF15.8

2023-09-18

OAAI

Cholankeril, George; Vierling, John M.

Nomenclature, diagnosis and management of drug-induced autoimmune-like hepatitis (DI-ALH): An expert opinion meeting report 药物诱导的自身免疫性肝炎 (di-alh) 的命名，诊断和管理: 专家意见会议报告

JOURNAL OF HEPATOLOGY

IF33

2023-09-01

OAAI

Andrade, Raul J.; Aithal, Guruprasad P.; de Boer, Ynto S.; Liberal, Rodrigo; Gerbes, Alexander; Regev, Arie; Beretta-Piccoli, Benedetta Terziroli; Schramm, Christoph; Kleiner, David E.; De Martin, Eleonora; Kullak-Ublick, Gerd A.; Stirnimann, Guido; Devarbhavi, Harshad; Vierling, John M.; Manns, Michael P.; Sebode, Marcial; Londono, Maria Carlota; Avigan, Mark; Robles-Diaz, Mercedes; Garcia-Cortes, Miren; Atallah, Edmond; Heneghan, Michael; Chalasani, Naga; Trivedi, Palak J.; Hayashi, Paul H.; Taubert, Richard; Fontana, Robert J.; Weber, Sabine; Oo, Ye Htun; Zen, Yoh; Licata, Anna; Lucena, M. Isabel; Mieli-Vergani, Giorgina; Vergani, Diego; Bjornsson, Einar S.

Seladelpar efficacy and safety at 3 months in patients with primary biliary cholangitis: ENHANCE, a phase 3, randomized, placebo-controlled study

HEPATOLOGY

IF15.8

2023-04-06

OAAI

Hirschfield, Gideon M.; Shiffman, Mitchell L.; Gulamhusein, Aliya; Kowdley, Kris, V; Vierling, John M.; Levy, Cynthia; Kremer, Andreas E.; Zigmond, Ehud; Andreone, Pietro; Gordon, Stuart C.; Bowlus, Christopher L.; Lawitz, Eric J.; Aspinall, Richard J.; Pratt, Daniel S.; Raikhelson, Karina; Gonzalez-Huezo, Maria S.; Heneghan, Michael A.; Jeong, Sook-Hyang; Ladron de Guevara, Alma L.; Mayo, Marlyn J.; Dalekos, George N.; Drenth, Joost P. H.; Janczewska, Ewa; Leggett, Barbara A.; Nevens, Frederik; Vargas, Victor; Zuckerman, Eli; Corpechot, Christophe; Fassio, Eduardo; Hinrichsen, Holger; Invernizzi, Pietro; Trivedi, Palak J.; Forman, Lisa; Jones, David E. J.; Ryder, Stephen D.; Swain, Mark G.; Steinberg, Alexandra; Boudes, Pol F.; Choi, Yun-Jung; McWherter, Charles A.

Tropifexor for nonalcoholic steatohepatitis: an adaptive, randomized, placebo-controlled phase 2a/b trial 托普非索用于治疗非酒精性脂肪性肝炎：一项适应性、随机、安慰剂对照的2a/2b期临床试验

NATURE MEDICINE

IF50

2023-02-16

OAAI

Sanyal, Arun J.; Lopez, Patricia; Lawitz, Eric J.; Lucas, Kathryn J.; Loeffler, Juergen; Kim, Won; Goh, George B. B.; Huang, Jee-Fu; Serra, Carla; Andreone, Pietro; Chen, Yi-Cheng; Hsia, Stanley H.; Ratziu, Vlad; Aizenberg, Diego; Tobita, Hiroshi; Sheikh, Aasim M.; Vierling, John M.; Kim, Yoon Jun; Hyogo, Hideyuki; Tai, Dean; Goodman, Zachary; Schaefer, Felicity; Carbarns, Ian R. I.; Lamle, Sophie; Martic, Miljen; Naoumov, Nikolai V.; Brass, Clifford A.

Prevalence and clinical significance of portal inflammation, portal plasma cells, interface hepatitis and biliary injury in liver biopsies from patients with non-alcoholic steatohepatitis

PATHOLOGY

IF3

2022-10-01

PREAI

Dhingra, Sadhna; Mahadik, Juhi D.; Tarabishy, Yaman; May, Sarah B.; Vierling, John M.

A phase II, randomized, open-label, 52-week study of seladelpar in patients with primary biliary cholangitis 原发性胆汁性胆管炎患者seladelpar的II期，随机，开放标签，为期52周的研究

JOURNAL OF HEPATOLOGY

IF33

2022-08-01

OAAI

Bowlus, Christopher L.; Galambos, Michael R.; Aspinall, Richard J.; Hirschfield, Gideon M.; Jones, David E. J.; Doerffel, Yvonne; Gordon, Stuart C.; Harrison, Stephen A.; Kremer, Andreas E.; Mayo, Marlyn J.; Thuluvath, Paul J.; Levy, Cynthia; Swain, Mark G.; Neff, Guy W.; Sheridan, David A.; Stanca, Carmen M.; Berg, Christoph P.; Goel, Aparna; Shiffman, Mitchell L.; Vierling, John M.; Boudes, Pol; Steinberg, Alexandra; Choi, Yun-Jung; McWherter, Charles A.

Systematic review of response criteria and endpoints in autoimmune hepatitis by the International Autoimmune Hepatitis Group 国际自身免疫性肝炎组对自身免疫性肝炎反应标准和终点的系统评价

JOURNAL OF HEPATOLOGY

IF33

2022-04-01

OAAI

Pape, Simon; Snijders, Romee J. A. L. M.; Gevers, Tom J. G.; Chazouilleres, Oliver; Dalekos, George N.; Hirschfield, Gideon M.; Lenzi, Marco; Trauner, Michael; Manns, Michael R.; Vierling, John M.; Montano-Loza, Aldo J.; Lohse, Ansgar W.; Schramm, Christoph; Drenth, Joost P. H.; Heneghan, Michael A.

Inter- and Intra-individual Variation, and Limited Prognostic Utility, of Serum Alkaline Phosphatase in a Trial of Patients With Primary Sclerosing Cholangitis

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY

IF12

2021-06-01

PREAI

Trivedi, Palak J.; Muir, Andrew J.; Levy, Cynthia; Bowlus, Christopher L.; Manns, Michael P.; Lu, Xiaomin; Crans, Gerald; Chung, Chuhan; Subramanian, G. Mani; Myers, Robert P.; Goodman, Zachary; Chalasani, Naga; Vierling, John M.; Guha, Indra Neil; Hirschfield, Gideon M.

研究方向