Struan F.A. Grant - Publications, H-index & Citations

Struan F.A. Grant

children's hospital of philadelphia

96H指数

638论文数

4.4W被引数

收录论文 252

发表时间

Genetic variation in BDNF is associated with opioid use disorder severity BDNF基因变异与阿片类药物使用障碍严重程度相关

Human Genetics

IF3.6

2026-09-19

OAAI

Dara M. Kusic; Matthew Salzman; Jessica Heil; Struan F. A. Grant; Khanh B. Trang; Stefan Zajic; Jozef Madzo; Christian Brown; Jaroslav Jelinek; Gennaro Calendo; Roland Schwarting; Jean-Pierre J. Issa; Laura B. Scheinfeldt

Geometry of the proximal femur during growth and its contribution to childhood fractures in healthy children 股骨近端在生长过程中的几何形态及其对健康儿童骨折的贡献

Journal of Bone and Mineral Research

IF5.9

2026-05-08

OAAI

Babette S Zemel; Jonathan A Mitchell; Andrea Kelly; David R Weber; Shana E McCormack; Joan M Lappe; Sharon E Oberfield; Dana L Duren; John A Shepherd; Devon Cataldi; Struan F A Grant; Heidi J Kalkwarf

The genetics of obesity: aetiology, prevention and therapy 肥胖的遗传学: 病因，预防和治疗

Nature Metabolism

IF20.8

2026-03-24

PREAI

Amélie Bonnefond; Winter S. Bruner; Struan F. A. Grant; Anita Morandi; Philippe Froguel

Cross-species evidence for a developmental origin of adult hypersomnia with loss of synaptic adhesion molecules beat-Ia/CADM2 跨物种证据表明，成人发作性睡病（hypersomnia）具有发育起源，并伴有突触黏附分子beat-Ia/CADM2的丢失。

Nature Communications

IF15.7

2026-01-12

OAAI

Kyla Mace; Amber Zimmerman; Alessandra Chesi; Fusun Doldur-Balli; Hayle Kim; Erika Almeraya del Valle; Jeffrey B. Rosa; Allan I. Pack; Struan F. A. Grant; Matthew S. Kayser

3D chromatin-based variant-to-gene maps across 57 human cell types reveal the cellular and genetic architecture of autoimmune disease susceptibility 基于3D染色质的变异-基因图谱在57种人类细胞类型中的研究揭示了自身免疫性疾病易感性的细胞和遗传架构

Genome Biology

IF9.4

2025-12-08

OAAI

Khanh B. Trang; Prabhat Sharma; Laura Cook; Zachary Mount; Rajan M. Thomas; Nikhil N. Kulkarni; Emylette Cruz Cabrera; Suzanna Rachimi; Matthew C. Pahl; James A. Pippin; Chun Su; Klaus H. Kaestner; Joan M. O’Brien; Yadav Wagley; Kurt D. Hankenson; Ashley Jermusyk; Jason W. Hoskins; Laufey T. Amundadottir; Mai Xu; Kevin M. Brown; Stewart A. Anderson; Wenli Yang; Paul M. Titchenell; Patrick Seale; Babette S. Zemel; Alessandra Chesi; Neil Romberg; Megan K. Levings; Struan F. A. Grant; Andrew D. Wells

The gSOS polygenic score is associated with bone density and fracture risk in childhood gSOS多基因评分与儿童期骨密度和骨折风险相关

JOURNAL OF BONE AND MINERAL RESEARCH

IF5.9

2025-11-01

PREAI

Mitchell, Jonathan A.; Bradfield, Jonathan; McCormack, Shana E.; Chesi, Alessandra; Kalkwarf, Heidi J.; Lappe, Joan M.; Oberfield, Sharon E.; Duren, Dana L.; Shepherd, John A.; Hankenson, Kurt D.; Kelly, Andrea; Hakonarson, Hakon; Grant, Struan F. A.; Zemel, Babette S.

Insomnia's psychiatric health connection through shared cellular programs 失眠与精神健康之间的联系：共享细胞程序的作用

SLEEP

IF4.9

2025-11-01

OAAI

Zimmerman, Amber J.; Grant, Struan F. A.; Gehrman, Philip

GWAS-informed data integration and non-coding CRISPRi screen illuminate genetic etiology of bone mineral density 全基因组关联研究指导的数据整合与非编码CRISPRi筛选阐明骨密度的遗传病因

Genome Biology

IF9.4

2025-10-04

OAAI

Mitchell Conery; James A. Pippin; Yadav Wagley; Khanh Trang; Matthew C. Pahl; David A. Villani; Lacey J. Favazzo; Cheryl L. Ackert-Bicknell; Michael J. Zuscik; Eugene Katsevich; Andrew D. Wells; Babette S. Zemel; Benjamin F. Voight; Kurt D. Hankenson; Alessandra Chesi; Struan F. A. Grant

Protocol for discovering genetic variants associated with ATAC-seq footprint-inferred transcription factor binding 发现与ATAC-seq足迹推断转录因子结合相关的遗传变异的方案

STAR PROTOCOLS

IF1.3

2025-10-01

OAAI

Dudek, Max F.; Wenz, Brandon M.; Voight, Benjamin F.; Almasy, Laura; Grant, Struan F. A.

Mapping chromatin interactions at melanoma susceptibility loci uncovers distant cis-regulatory gene targets 绘制黑色素瘤易感位点的染色质相互作用图谱，揭示了远端顺式调控基因靶点

american journal of human genetics

IF0

2025-05-22

PREAI

Rohit Thakur; Mai Xu; Hayley Sowards; Joshuah Yon; Lea Jessop; Timothy Myers; Tongwu Zhang; Raj Chari; Erping Long; Thomas Rehling; Rebecca Hennessey; Karen Funderburk; Jinhu Yin; Mitchell J. Machiela; Matthew E. Johnson; Andrew D. Wells; Alessandra Chesi; Struan F.A. Grant; Mark M. Iles; Maria Teresa Landi; Matthew H. Law; Jiyeon Choi; Kevin M. Brown

Trans-ancestry genome-wide association study of childhood body mass index identifies novel loci and age-specific effects

HUMAN GENETICS AND GENOMICS ADVANCES

IF3.6

2025-04-01

OAAI

Downie, Carolina G.; Shrestha, Poojan; Okello, Samson; Yaser, Mohammad; Lee, Harold H.; Wang, Yujie; Josyula, Navya Shilpa; Gahagan, Sheila; Burrows, Raquel; Correa-Burrows, Paulina; Albala, Cecilia; Santos, Jose L.; Angel, Barbara; Lozoff, Betsy; Blanco, Estela; Hartwig, Fernando Pires; Horta, Bernardo; Brina, Karisa Roxo; Isasi, Carmen R.; Qi, Qibin; Gallo, Linda C.; Perreira, Krista M.; Thyagarajan, Bharat; Daviglus, Martha; Van Horn, Linda; Chittoor, Geetha; Justice, Anne E.; Krishnan, Mohanraj; Chen, Hung-Hsin; Gonzalez, Franklyn; Bradfield, Jonathan P.; Hakonarson, Hakon; Grant, Struan F. A.; Below, Jennifer E.; Felix, Janine; Graff, Mariaelisa; Divaris, Kimon; North, Kari E.

Race-neutral Pediatric Reference Ranges for Bone Mineral Density Predict Prospective Fractures in Childhood 种族无关的儿科骨密度参考范围可预测儿童期骨折

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

IF5.1

2025-03-25

PREAI

Zemel, Babette S.; Winer, Karen K.; Kelly, Andrea; Freedman, David S.; Mitchell, Jonathan A.; Weber, David R.; Mccormack, Shana E.; Mcwilliams, Tara; Lappe, Joan M.; Oberfield, Sharon E.; Shepherd, John A.; Grant, Struan F. A.; Kalkwarf, Heidi J.

3D genomic features across >50 diverse cell types reveal insights into the genomic architecture of childhood obesity

ELIFE

IF0

2025-01-15

OAAI

Trang, Khanh B.; Pahl, Matthew C.; Pippin, James A.; Su, Chun; Littleton, Sheridan H.; Sharma, Prabhat; Kulkarni, Nikhil N.; Ghanem, Louis R.; Terry, Natalie A.; O'Brien, Joan M.; Wagley, Yadav; Hankenson, Kurt D.; Jermusyk, Ashley; Hoskins, Jason; Amundadottir, Laufey T.; Xu, Mai; Brown, Kevin; Anderson, Stewart; Yang, Wenli; Titchenell, Paul; Seale, Patrick; Kaestner, Klaus H.; Cook, Laura; Levings, Megan; Zemel, Babette S.; Chesi, Alessandra; Wells, Andrew D.; Grant, Struan F. A.

Bridging sleep with psychiatric disorders through genetics 通过遗传学将睡眠与精神疾病联系起来

SLEEP

IF4.9

2024-10-04

OAAI

Zimmerman, Amber J.; Grant, Struan F. A.

Dynamic chromatin architecture identifies new autoimmune-associated enhancers for IL2 and novel genes regulating CD4+T cell activation 动态染色质结构鉴定IL2的新自身免疫相关增强子和调节CD4 T细胞活化的新基因

ELIFE

IF0

2024-09-20

OAAI

Pahl, Matthew C.; Sharma, Prabhat; Thomas, Rajan M.; Thompson, Zachary; Mount, Zachary; Pippin, James A.; Morawski, Peter A.; Sun, Peng; Su, Chun; Campbell, Daniel; Grant, Struan F. A.; Wells, Andrew D.

Implicating type 2 diabetes effector genes in relevant metabolic cellular models using promoter-focused Capture-C 使用启动子聚焦的capture-c在相关代谢细胞模型中暗示2型糖尿病效应基因

DIABETOLOGIA

IF10.2

2024-09-06

OAAI

Wachowski, Nicholas A.; Pippin, James A.; Boehm, Keith; Lu, Sumei; Leonard, Michelle E.; Manduchi, Elisabetta; Parlin, Ursula W.; Wabitsch, Martin; Chesi, Alessandra; Wells, Andrew D.; Grant, Struan F. A.; Pahl, Matthew C.

Understanding the genetic complexity of puberty timing across the allele frequency spectrum 了解等位基因频谱中青春期时间的遗传复杂性

NATURE GENETICS

IF31.8

2024-07-01

OAAI

Kentistou, Katherine A.; Kaisinger, Lena R.; Stankovic, Stasa; Vaudel, Marc; de Oliveira, Edson Mendes; Messina, Andrea; Walters, Robin G.; Liu, Xiaoxi; Busch, Alexander S.; Helgason, Hannes; Thompson, Deborah J.; Santoni, Federico; Petricek, Konstantin M.; Zouaghi, Yassine; Huang-Doran, Isabel; Gudbjartsson, Daniel F.; Bratland, Eirik; Lin, Kuang; Gardner, Eugene J.; Zhao, Yajie; Jia, Raina Y.; Terao, Chikashi; Riggan, Marjorie J.; Bolla, Manjeet K.; Yazdanpanah, Mojgan; Yazdanpanah, Nahid; Bradfield, Jonathan P.; Broer, Linda; Campbell, Archie; Chasman, Daniel I.; Cousminer, Diana L.; Franceschini, Nora; Franke, Lude H.; Girotto, Giorgia; He, Chunyan; Jarvelin, Marjo-Riitta; Joshi, Peter K.; Kamatani, Yoichiro; Karlsson, Robert; Luan, Jian'an; Lunetta, Kathryn L.; Magi, Reedik; Mangino, Massimo; Medland, Sarah E.; Meisinger, Christa; Noordam, Raymond; Nutile, Teresa; Concas, Maria Pina; Polasek, Ozren; Porcu, Eleonora; Ring, Susan M.; Sala, Cinzia; Smith, Albert V.; Tanaka, Toshiko; Van der Most, Peter J.; Vitart, Veronique; Wang, Carol A.; Willemsen, Gonneke; Zygmunt, Marek; Ahearn, Thomas U.; Andrulis, Irene L.; Anton-Culver, Hoda; Antoniou, Antonis C.; Auer, Paul L.; Barnes, Catriona L. K.; Beckmann, Matthias W.; de Gonzalez, Amy Berrington; Bogdanova, Natalia V.; Bojesen, Stig E.; Brenner, Hermann; Buring, Julie E.; Canzian, Federico; Chang-Claude, Jenny; Couch, Fergus J.; Cox, Angela; Crisponi, Laura; Czene, Kamila; Daly, Mary B.; Demerath, Ellen W.; Dennis, Joe; Devilee, Peter; De Vivo, Immaculata; Doerk, Thilo; Dunning, Alison M.; Dwek, Miriam; Eriksson, Johan G.; Fasching, Peter A.; Fernandez-Rhodes, Lindsay; Ferreli, Liana; Fletcher, Olivia; Gago-Dominguez, Manuela; Garcia-Closas, Montserrat; Garcia-Saenz, Jose A.; Gonzalez-Neira, Anna; Grallert, Harald; Guenel, Pascal; Haiman, Christopher A.; Hall, Per; Hamann, Ute; Hakonarson, Hakon; Hart, Roger J.; Hickey, Martha; Hooning, Maartje J.; Hoppe, Reiner; Hopper, John L.; Hottenga, Jouke-Jan; Hu, Frank B.; Huebner, Hanna; Hunter, David J.; Jernstrom, Helena; John, Esther M.; Karasik, David; Khusnutdinova, Elza K.; Kristensen, Vessela N.; Lacey, James V.; Lambrechts, Diether; Launer, Lenore J.; Lind, Penelope A.; Lindblom, Annika; Magnusson, Patrik K. E.; Mannermaa, Arto; McCarthy, Mark I.; Meitinger, Thomas; Menni, Cristina; Michailidou, Kyriaki; Millwood, Iona Y.; Milne, Roger L.; Montgomery, Grant W.; Nevanlinna, Heli; Nolte, Ilja M.; Nyholt, Dale R.; Obi, Nadia; O'Brien, Katie M.; Offit, Kenneth; Oldehinkel, Albertine J.; Ostrowski, Sisse R.; Palotie, Aarno; Pedersen, Ole B.; Peters, Annette; Pianigiani, Giulia; Plaseska-Karanfilska, Dijana; Pouta, Anneli; Pozarickij, Alfred; Radice, Paolo; Rennert, Gad; Rosendaal, Frits R.; Ruggiero, Daniela; Saloustros, Emmanouil; Sandler, Dale P.; Schipf, Sabine; Schmidt, Carsten O.; Schmidt, Marjanka K.; Small, Kerrin; Spedicati, Beatrice; Stampfer, Meir; Stone, Jennifer; Tamimi, Rulla M.; Teras, Lauren R.; Tikkanen, Emmi; Turman, Constance; Vachon, Celine M.; Wang, Qin; Winqvist, Robert; Wolk, Alicja; Zemel, Babette S.; Zheng, Wei; van Dijk, Ko W.; Alizadeh, Behrooz Z.; Bandinelli, Stefania; Boerwinkle, Eric; Boomsma, Dorret I.; Ciullo, Marina; Chenevix-Trench, Georgia; Cucca, Francesco; Esko, Tonu; Gieger, Christian; Grant, Struan F. A.; Gudnason, Vilmundur; Hayward, Caroline; Kolcic, Ivana; Kraft, Peter; Lawlor, Deborah A.; Martin, Nicholas G.; Nohr, Ellen A.; Pedersen, Nancy L.; Pennell, Craig E.; Ridker, Paul M.; Robino, Antonietta; Snieder, Harold; Sovio, Ulla; Spector, Tim D.; Stockl, Doris; Sudlow, Cathie; Timpson, Nic J.; Toniolo, Daniela; Uitterlinden, Andre; Ulivi, Sheila; Volzke, Henry; Wareham, Nicholas J.; Widen, Elisabeth; Wilson, James F.; Pharoah, Paul D. P.; Li, Liming; Easton, Douglas F.; Njolstad, Pal R.; Sulem, Patrick; Murabito, Joanne M.; Murray, Anna; Manousaki, Despoina; Juul, Anders; Erikstrup, Christian; Stefansson, Kari; Horikoshi, Momoko; Chen, Zhengming; Farooqi, I. Sadaf; Pitteloud, Nelly; Johansson, Stefan; Day, Felix R.; Perry, John R. B.; Ong, Ken K.

Initial eQTL Discovery in Individual Pancreatic Cell Types from the Human Pancreas Analysis Program

DIABETES

IF7.5

2024-06-14

PREAI

Weidekamp, Mary A.; Elgamal, Ruth; Lorenz, Kimberly; Kaestner, Klaus H.; Gaulton, Kyle J.; Grant, Struan F.; Voight, Benjamin F.

Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3 0 UTR of FAIM2 儿童肥胖chr12q13基因座的变异型功能分析表明，rs7132908是FAIM2 3 0 UTR内的因果变异。

CELL GENOMICS

IF9

2024-05-01

OAAI

Littleton, Sheridan H.; Trang, Khanh B.; Volpe, Christina M.; Cook, Kieona; DeBruyne, Nicole; Maguire, Jean Ann; Weidekamp, Mary Ann; Hodge, Kenyaita M.; Boehm, Keith; Lu, Sumei; Chesi, Alessandra; Bradfield, Jonathan P.; Pippin, James A.; Anderson, Stewart A.; Wells, Andrew D.; Pahl, Matthew C.; Grant, Struan F. A.

Foxp3 depends on Ikaros for control of regulatory T cell gene expression and function Foxp3依赖Ikaros控制调节性T细胞基因的表达和功能

ELIFE

IF0

2024-04-24

OAAI

Thomas, Rajan M.; Pahl, Matthew C.; Wang, Liqing; Grant, Struan F. A.; Hancock, Wayne W.; Wells, Andrew D.

研究方向