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INTERSTITIAL LUNG ABNORMALITIES AND CORONARY HEART DISEASE IN COPD GENE Cutting, Claire; Rose, Jonathan; Tukpah, AnnMarcia; Wada, Noriaki; Nishino, Mizuki; Moll, Matthew; Cho, Michael; Silverman, Edwin; Washko, George; Kinney, Gregory L.; Hokanson, John; Rossiter, Harry B.; Budoff, Matthew; Hatabu, Hiroto; Hunninghake, Gary M.; Putman, Rachel 分享 收藏
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New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries (vol 51, pg 481, 2019) 跨多个祖先的肺功能突出通路和慢性阻塞性肺疾病关联的新遗传信号 (第51卷，481页，2019) Shrine, Nick; Guyatt, Anna L.; Erzurumluoglu, A. Mesut; Jackson, Victoria E.; Hobbs, Brian D.; Melbourne, Carl A.; Batini, Chiara; Fawcett, Katherine A.; Song, Kijoung; Sakornsakolpat, Phuwanat; Li, Xingnan; Boxall, Ruth; Reeve, Nicola F.; Obeidat, Ma'en; Zhao, Jing Hua; Wielscher, Matthias; Weiss, Stefan; Kentistou, Katherine A.; Cook, James P.; Sun, Benjamin B.; Zhou, Jian; Hui, Jennie; Karrasch, Stefan; Imboden, Medea; Harris, Sarah E.; Marten, Jonathan; Enroth, Stefan; Kerr, Shona M.; Surakka, Ida; Vitart, Veronique; Lehtimaeki, Terho; Allen, Richard J.; Bakke, Per S.; Beaty, Terri H.; Bleecker, Eugene R.; Bosse, Yohan; Brandsma, Corry-Anke; Chen, Zhengming; Crapo, James D.; Danesh, John; DeMeo, Dawn L.; Dudbridge, Frank; Ewert, Ralf; Gieger, Christian; Gulsvik, Amund; Hansell, Anna L.; Hao, Ke; Hoffman, Joshua D.; Hokanson, John E.; Homuth, Georg; Joshi, Peter K.; Joubert, Philippe; Langenberg, Claudia; Li, Xuan; Li, Liming; Lin, Kuang; Lind, Lars; Locantore, Nicholas; Luan, Jian'an; Mahajan, Anubha; Maranville, Joseph C.; Murray, Alison; Nickle, David C.; Packer, Richard; Parker, Margaret M.; Paynton, Megan L.; Porteous, David J.; Prokopenko, Dmitry; Qiao, Dandi; Rawal, Rajesh; Runz, Heiko; Sayers, Ian; Sin, Don D.; Smith, Blair H.; Artigas, Maria Soler; Sparrow, David; Tal-Singer, Ruth; Timmers, Paul R. H. J.; Van den Berge, Maarten; Whittaker, John C.; Woodruff, Prescott G.; Yerges-Armstrong, Laura M.; Troyanskaya, Olga G.; Raitakari, Olli T.; Kaehoenen, Mika; Polasek, Ozren; Gyllensten, Ulf; Rudan, Igor; Deary, Ian J.; Probst-Hensch, Nicole M.; Schulz, Holger; James, Alan L.; Wilson, James F.; Stubbe, Beate; Zeggini, Eleftheria; Jarvelin, Marjo-Riitta; Wareham, Nick; Silverman, Edwin K.; Hayward, Caroline; Morris, Andrew P.; Butterworth, Adam S.; Scott, Robert A.; Walters, Robin G.; Meyers, Deborah A.; Cho, Michael H.; Strachan, David P.; Hall, Ian P.; Tobin, Martin D.; Wain, Louise V. 分享 收藏
Whole-genome sequencing uncovers two loci for coronary artery calcification and identifies ARSE as a regulator of vascular calcification 全基因组测序揭示了冠状动脉钙化的两个基因座，并将ARSE鉴定为血管钙化的调节剂 de Vries, Paul S.; Conomos, Matthew P.; Singh, Kuldeep; Nicholson, Christopher J.; Jain, Deepti; Hasbani, Natalie R.; Jiang, Wanlin; Lee, Sujin; Lino Cardenas, Christian L.; Lutz, Sharon M.; Wong, Doris; Guo, Xiuqing; Yao, Jie; Young, Erica P.; Tcheandjieu, Catherine; Hilliard, Austin T.; Bis, Joshua C.; Bielak, Lawrence F.; Brown, Michael R.; Musharoff, Shaila; Clarke, Shoa L.; Terry, James G.; Palmer, Nicholette D.; Yanek, Lisa R.; Xu, Huichun; Heard-Costa, Nancy; Wessel, Jennifer; Selvaraj, Margaret Sunitha; Li, Rebecca H.; Sun, Xiao; Turner, Adam W.; Stilp, Adrienne M.; Khan, Alyna; Newman, Anne B.; Rasheed, Asif; Freedman, Barry I.; Kral, Brian G.; McHugh, Caitlin P.; Hodonsky, Chani; Saleheen, Danish; Herrington, David M.; Jacobs, David R., Jr.; Nickerson, Deborah A.; Boerwinkle, Eric; Wang, Fei Fei; Heiss, Gerardo; Jun, Goo; Kinney, Greg L.; Sigurslid, Haakon H.; Doddapaneni, Harshavardhan; Hall, Ira M.; Bensenor, Isabela M.; Broome, Jai; Crapo, James D.; Wilson, James G.; Smith, Jennifer A.; Blangero, John; Vargas, Jose D.; Mosquera, Jose Verdezoto; Smith, Joshua D.; Viaud-Martinez, Karine A.; Ryan, Kathleen A.; Young, Kendra A.; Taylor, Kent D.; Lange, Leslie A.; Emery, Leslie S.; Bittencourt, Marcio S.; Budoff, Matthew J.; Montasser, May E.; Yu, Miao; Mahaney, Michael C.; Mahamdeh, Mohammed S.; Fornage, Myriam; Franceschini, Nora; Lotufo, Paulo A.; Natarajan, Pradeep; Wong, Quenna; Mathias, Rasika A.; Gibbs, Richard A.; Do, Ron; Mehran, Roxana; Tracy, Russell P.; Kim, Ryan W.; Nelson, Sarah C.; Damrauer, Scott M.; Kardia, Sharon L. R.; Rich, Stephen S.; Fuster, Valentin; Napolioni, Valerio; Zhao, Wei; Tian, Wenjie; Yin, Xianyong; Min, Yuan-, I; Manning, Alisa K.; Peloso, Gina; Kelly, Tanika N.; O'Donnell, Christopher J.; Morrison, Alanna C.; Curran, Joanne E.; Zapol, Warren M.; Bowden, Donald W.; Becker, Lewis C.; Correa, Adolfo; Mitchell, Braxton D.; Psaty, Bruce M.; Carr, John Jeffrey; Pereira, Alexandre C.; Assimes, Themistocles L.; Stitziel, Nathan O.; Hokanson, John E.; Laurie, Cecelia A.; Rotter, Jerome I.; Vasan, Ramachandran S.; Post, Wendy S.; Peyser, Patricia A.; Miller, Clint L.; Malhotra, Rajeev 分享 收藏
Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification 多血统全基因组研究确定冠状动脉钙化的效应基因和药物途径 Kavousi, Maryam; Bos, Maxime M.; Barnes, Hanna J.; Cardenas, Christian L. Lino; Wong, Doris; Lu, Haojie; Hodonsky, Chani J.; Landsmeer, Lennart P. L.; Turner, Adam W.; Kho, Minjung; Hasbani, Natalie R.; de Vries, Paul S.; Bowden, Donald W.; Chopade, Sandesh; Deelen, Joris; Benavente, Ernest Diez; Guo, Xiuqing; Hofer, Edith; Hwang, Shih-Jen; Lutz, Sharon M.; Lyytikainen, Leo-Pekka; Slenders, Lotte; Smith, Albert V.; Stanislawski, Maggie A.; van Setten, Jessica; Wong, Quenna; Yanek, Lisa R.; Becker, Diane M.; Beekman, Marian; Budoff, Matthew J.; Feitosa, Mary F.; Finan, Chris; Hilliard, Austin T.; Kardia, Sharon L. R.; Kovacic, Jason C.; Kral, Brian G.; Langefeld, Carl D.; Launer, Lenore J.; Malik, Shaista; Hoesein, Firdaus A. A. Mohamed; Mokry, Michal; Schmidt, Reinhold; Smith, Jennifer A.; Taylor, Kent D.; Terry, James G.; van der Grond, Jeroen; van Meurs, Joyce; Vliegenthart, Rozemarijn; Xu, Jianzhao; Young, Kendra A.; Zilhao, Nuno R.; Zweiker, Robert; Assimes, Themistocles L.; Becker, Lewis C.; Bos, Daniel; Carr, J. Jeffrey; Cupples, L. Adrienne; de Kleijn, Dominique P. V.; de Winther, Menno; den Ruijter, Hester M.; Fornage, Myriam; Freedman, Barry I.; Gudnason, Vilmundur; Hingorani, Aroon D.; Hokanson, John E.; Ikram, M. Arfan; Isgum, Ivana; Jacobs, David R., Jr.; Kahonen, Mika; Lange, Leslie A.; Lehtimaki, Terho; Pasterkamp, Gerard; Raitakari, Olli T.; Schmidt, Helena; Slagboom, P. Eline; Uitterlinden, Andre G.; Vernooij, Meike W.; Bis, Joshua C.; Franceschini, Nora; Psaty, Bruce M.; Post, Wendy S.; Rotter, Jerome I.; Bjorkegren, Johan L. M.; O'Donnell, Christopher J.; Bielak, Lawrence F.; Peyser, Patricia A.; Malhotra, Rajeev; van der Laan, Sander W.; Miller, Clint L. 分享 收藏
Genome-wide association meta-analysis identifies 17 loci associated with nonalcoholic fatty liver disease 全基因组关联荟萃分析确定了17个与非酒精性脂肪性肝病相关的基因座 Chen, Yanhua; Du, Xiaomeng; Kuppa, Annapurna; Feitosa, Mary F.; Bielak, Lawrence F.; O'Connell, Jeffrey R.; Musani, Solomon K.; Guo, Xiuqing; Kahali, Bratati; Chen, Vincent L.; Smith, Albert V.; Ryan, Kathleen A.; Eirksdottir, Gudny; Allison, Matthew A.; Bowden, Donald W.; Budoff, Matthew J.; Carr, John Jeffrey; Chen, Yii-Der I.; Taylor, Kent D.; Oliveri, Antonino; Correa, Adolfo; Crudup, Breland F.; Kardia, Sharon L. R.; Mosley, Thomas H.; Norris, Jill M.; Terry, James G.; Rotter, Jerome I.; Wagenknecht, Lynne E.; Halligan, Brian D.; Young, Kendra A.; Hokanson, John E.; Washko, George R.; Gudnason, Vilmundur; Province, Michael A.; Peyser, Patricia A.; Palmer, Nicholette D.; Speliotes, Elizabeth K. 分享 收藏
Causes of and Clinical Features Associated with Death in Tobacco Cigarette Users by Lung Function Impairment Labaki, Wassim W.; Gu, Tian; Murray, Susan; Curtis, Jeffrey L.; Wells, J. Michael; Bhatt, Surya P.; Bon, Jessica; Diaz, Alejandro A.; Hersh, Craig P.; Wan, Emily S.; Kim, Victor; Beaty, Terri H.; Hokanson, John E.; Bowler, Russell P.; Arenberg, Douglas A.; Kazerooni, Ella A.; Martinez, Fernando J.; Silverman, Edwin K.; Crapo, James D.; Make, Barry J.; Regan, Elizabeth A.; Han, MeiLan K. 分享 收藏
Mendelian randomization study of diabetes and dementia in the Million Veteran Program 百万退伍军人计划中糖尿病和痴呆的孟德尔随机化研究 Litkowski, Elizabeth M. W.; Logue, Mark W.; Zhang, Rui R.; Charest, Brian R. M.; Lange, Ethan M. E.; Hokanson, John E. A.; Lynch, Julie A.; Vujkovic, Marijana S.; Phillips, Lawrence S. L.; Hauger, Richard L. A.; Lange, Leslie A.; Raghavan, Sridharan 分享 收藏
Heterogeneity and Progression of Chronic Obstructive Pulmonary Disease: Emphysema-Predominant and Non-Emphysema-Predominant Disease Castaldi, Peter J.; Xu, Zhonghui; Young, Kendra A.; Hokanson, John E.; Lynch, David A.; Humphries, Stephen M.; Ross, James C.; Cho, Michael H.; Hersh, Craig P.; Crapo, James D.; Strand, Matthew; Silverman, Edwin K. 分享 收藏
Use of the Spirometric Fixed-Ratio Underdiagnoses COPD in African-Americans in a Longitudinal Cohort Study Regan, Elizabeth A.; Lowe, Melissa E.; Make, Barry J.; Curtis, Jeffrey L.; Chen, Quan (Grace); Cho, Michael H.; Crooks, James L.; Lowe, Katherine E.; Wilson, Carla; O'Brien, James K.; Oates, Gabriela R.; Baldomero, Arianne K.; Kinney, Gregory L.; Young, Kendra A.; Diaz, Alejandro A.; Bhatt, Surya P.; McCormack, Meredith C.; Hansel, Nadia N.; Kim, Victor; Richmond, Nicole E.; Westney, Gloria E.; Foreman, Marilyn G.; Conrad, Douglas J.; DeMeo, Dawn L.; Hoth, Karin F.; Amaza, Hannatu; Balasubramanian, Aparna; Kallet, Julia; Watts, Shandi; Hanania, Nicola A.; Hokanson, John; Beaty, Terri H.; Crapo, James D.; Silverman, Edwin K.; Casaburi, Richard; Wise, Robert 分享 收藏
Prevalence of abnormal spirometry in individuals with a smoking history and no known obstructive lung disease 有吸烟史且无已知阻塞性肺病的个体中异常肺活量测定的患病率 Tran, Thuonghien V.; Kinney, Gregory L.; Comellas, Alejandro; Hoth, Karin F.; Baldomero, Arianne K.; Mamary, A. James; Curtis, Jeffrey L.; Hanania, Nicola; Casaburi, Richard; Young, Kendra A.; Kim, Victor; Make, Barry; Wan, Emily S.; Diaz, Alejandro A.; Hokanson, John; Crapo, James D.; Silverman, Edwin K.; Bhatt, Surya P.; Regan, Elizabeth; Fortis, Spyridon 分享 收藏
Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing 多血统转录组全关联分析产生了对烟草使用生物学和药物再利用的见解 Chen, Fang; Wang, Xingyan; Jang, Seon-Kyeong; Quach, Bryan C.; Weissenkampen, J. Dylan; Khunsriraksakul, Chachrit; Yang, Lina; Sauteraud, Renan; Albert, Christine M.; Allred, Nicholette D. D.; Arnett, Donna K.; Ashley-Koch, Allison E.; Barnes, Kathleen C.; Barr, R. Graham; Becker, Diane M.; Bielak, Lawrence F.; Bis, Joshua C.; Blangero, John; Boorgula, Meher Preethi; Chasman, Daniel I.; Chavan, Sameer; Chen, Yii-Der I.; Chuang, Lee-Ming; Correa, Adolfo; Curran, Joanne E.; David, Sean P.; de las Fuentes, Lisa; Deka, Ranjan; Duggirala, Ravindranath; Faul, Jessica D.; Garrett, Melanie E.; Gharib, Sina A.; Guo, Xiuqing; Hall, Michael E.; Hawley, Nicola L.; He, Jiang; Hobbs, Brian D.; Hokanson, John E.; Hsiung, Chao A.; Hwang, Shih-Jen; Hyde, Thomas M.; Irvin, Marguerite R.; Jaffe, Andrew E.; Johnson, Eric O.; Kaplan, Robert; Kardia, Sharon L. R.; Kaufman, Joel D.; Kelly, Tanika N.; Kleinman, Joel E.; Kooperberg, Charles; Lee, I-Te; Levy, Daniel; Lutz, Sharon M.; Manichaikul, Ani W.; Martin, Lisa W.; Marx, Olivia; McGarvey, Stephen T.; Minster, Ryan L.; Moll, Matthew; Moussa, Karine A.; Naseri, Take; North, Kari E.; Oelsner, Elizabeth C.; Peralta, Juan M.; Peyser, Patricia A.; Psaty, Bruce M.; Rafaels, Nicholas; Raffield, Laura M.; Reupena, Muagututi'a Sefuiva; Rich, Stephen S.; Rotter, Jerome I.; Schwartz, David A.; Shadyab, Aladdin H.; Sheu, Wayne H-H.; Sims, Mario; Smith, Jennifer A.; Sun, Xiao; Taylor, Kent D.; Telen, Marilyn J.; Watson, Harold; Weeks, Daniel E.; Weir, David R.; Yanek, Lisa R.; Young, Kendra A.; Young, Kristin L.; Zhao, Wei; Hancock, Dana B.; Jiang, Bibo; Vrieze, Scott; Liu, Dajiang J. 分享 收藏
A Diabetes Genetic Risk Score Is Associated With All-Cause Dementia and Clinically Diagnosed Vascular Dementia in the Million Veteran Program Litkowski, Elizabeth M.; Logue, Mark W.; Zhang, Rui; Charest, Brian R.; Lange, Ethan M.; Hokanson, John E.; Lynch, Julie A.; Vujkovic, Marijana; Phillips, Lawrence S.; Lange, Leslie A.; Hauger, Richard L.; Raghavan, Sridharan 分享 收藏
GAWMerge expands GWAS sample size and diversity by combining array-based genotyping and whole-genome sequencing Mathur, Ravi; Fang, Fang; Gaddis, Nathan; Hancock, Dana B.; Cho, Michael H.; Hokanson, John E.; Bierut, Laura J.; Lutz, Sharon M.; Young, Kendra; Smith, Albert, V; Silverman, Edwin K.; Page, Grier P.; Johnson, Eric O. 分享 收藏
Identifying Individual Medications Affecting Pulmonary Outcomes When Multiple Medications are Present Li, Yisha; Dai, Ran; Gwon, Yeongjin; Rennard, Stephen, I; Make, Barry J.; Foer, Dinah; Strand, Matthew J.; Austin, Erin; Young, Kendra A.; Hokanson, John E.; Pratte, Katherine A.; Conway, Rebecca; Kinney, Gregory L. 分享 收藏
Longitudinal Association Between Muscle Loss and Mortality in Ever Smokers Mason, Stefanie E.; Moreta-Martinez, Rafael; Labaki, Wassim W.; Strand, Matthew J.; Regan, Elizabeth A.; Bon, Jessica; Estepar, Ruben San Jose; Casaburi, Richard; McDonald, Merry-Lynn; Rossiter, Harry B.; Make, Barry; Dransfield, Mark T.; Han, MeiLan K.; Young, Kendra; Curtis, Jeffrey L.; Stringer, Kathleen; Kinney, Greg; Hokanson, John E.; Estepar, Raul San Jose; Washko, George R. 分享 收藏
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Significant Spirometric Transitions and Preserved Ratio Impaired Spirometry Among Ever Smokers Wan, Emily S.; Hokanson, John E.; Regan, Elizabeth A.; Young, Kendra A.; Make, Barry J.; DeMeo, Dawn L.; Mason, Stefanie E.; Estepar, Raul San Jose; Crapo, James D.; Silverman, Edwin K. 分享 收藏
10-Year Follow-Up of Lung Function, Respiratory Symptoms, and Functional Capacity in the COPDGene Study Ragland, Margaret F.; Strand, Matthew; Baraghoshi, David; Young, Kendra A.; Kinney, Gregory L.; Austin, Erin; Hokanson, John E.; Regan, Elizabeth; Crapo, James; Silverman, Edwin K.; Make, Barry 分享 收藏
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