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T

Takashi Okiji

Graduate School of Medical and Dental Sciences
H指数:39
被引数:5,755

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Temporal immunohistochemical analysis of macrophage, neutrophil, and osteoclast dynamics during metformin-mediated suppression of experimentally induced apical periodontitis in mice

在小鼠实验性诱导的根尖周炎中，二甲双胍介导抑制期间巨噬细胞、中性粒细胞和破骨细胞动态的时间免疫组化分析

BMC Oral Health
IF3.1
2026-08-180
OA
Faisal Alghamdi; Kento Tazawa; Chunmei Ren; Shuaichen Liu; Chuyi Zhou; Junnosuke Takahashi; Risa Ohshima; Masaharu Ishidori; Toka Fukubayashi; Nobuyuki Kawashima; Takashi Okiji; Yoshio Yahata
Metformin suppresses periapical bone resorption in a mouse model of apical periodontitis in vivo and inhibits RANKL-induced osteoclastogenesis in vitro

二甲双胍在体内抑制根尖周炎小鼠模型中的根尖骨吸收，并在体外抑制RANKL诱导的破骨细胞生成

Journal of Oral Biosciences
IF2.3
2026-07-040
PRE
Faisal Alghamdi; Chunmei Ren; Kento Tazawa; Shuaichen Liu; Chuyi Zhou; Junnosuke Takahashi; Masaharu Ishidori; Risa Ohshima; Nobuyuki Kawashima; Takashi Okiji; Yoshio Yahata
Metformin attenuates alveolar bone destruction in mice with apical periodontitis and inhibits pro-inflammatory cytokine synthesis in lipopolysaccharide-stimulated RAW264.7 through the AMPK-mTOR-NF-κB pathway

二甲双胍通过AMPK-mTOR-NF-κB通路减轻根尖周炎小鼠的牙槽骨破坏，并在脂多糖刺激的RAW264.7细胞中抑制促炎细胞因子的合成

Frontiers in Immunology
IF5.9
2025-08-020
OA
Chunmei Ren; Kento Tazawa; Nobuyuki Kawashima; Risa Ohshima; Yamato Okada; Shihan Wang; Ziniu Yu; Peifeng Han; Yujin Ohsugi; Sayaka Katagiri; Takashi Okiji

研究方向

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N
Nobuyuki Kawashima
H 指数:25论文数:91被引数:2,340
T
Tomoatsu Kaneko
H 指数:18论文数:56被引数:1,524
A
Arata Ebihara
H 指数:24论文数:113被引数:1,839
K
Keiichiro Maki
H 指数:12论文数:37被引数:377
S
Shunsuke Kimura
H 指数:12论文数:43被引数:984
H 指数:0论文数:406被引数:5,756
N
Nagako Yoshiba
H 指数:26论文数:88被引数:1,945
K
Kunihiko Yoshiba
H 指数:27论文数:114被引数:1,926
K
Kentaro Hashimoto
H 指数:14论文数:75被引数:526
S
Sonoko Noda
H 指数:11论文数:21被引数:408