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R

Ryo Otsuka

Nagoya City University
H指数:26
被引数:3,038

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Multiple human transgenes prolong survival of triple-carbohydrate knockout porcine kidney xenografts in nonhuman primates

多种人类转基因可延长三糖缺失猪肾异种移植物在非人灵长类动物中的存活时间

Nature Communications
IF15.7
2026-06-270
OAAI
Ahmad Karadagi; Takayuki Hirose; Grace Lassiter; Ivy Rosales; David Ma; Toshihide Tomosugi; Ryo Otsuka; Ranjith P. Anand; Jacob V. Layer; Jia-Yun Chen; Sandro Santagata; Michael Curtis; Susan Low; Wenning Qin; Robert B. Colvin; Tatsuo Kawai
Identification of a critical gene involved in the biosynthesis of the polyene macrolide lavencidin in Streptomyces lavendulae FRI-5 using the Target-AID (activation-induced cytidine deaminase) base editing technology

利用Target-AID（激活诱导的胞嘧啶脱氨酶）碱基编辑技术鉴定了链霉菌Streptomyces lavendulae FRI-5中参与聚烯大环内酯lavencidin生物合成的一个关键基因。

APPLIED AND ENVIRONMENTAL MICROBIOLOGY
IF3.7
2025-05-210
OA
Otsuka, Ryo; Sato, Yu; Okano, Kenji; Okamura, Eiji; Tomita, Hiroya; Honda, Kohsuke; Kitani, Shigeru
TNX-1500, a crystallizable fragment-modified anti-CD154 antibody, prolongs nonhuman primate renal allograft survival
AMERICAN JOURNAL OF TRANSPLANTATION
IF8.2
2023-08-0110
OA
Lassiter, Grace; Otsuka, Ryo; Hirose, Takayuki; Rosales, Ivy; Karadagi, Ahmad; Tomosugi, Toshihide; Dehnadi, Abbas; Lee, Hang; Colvin, Robert B.; Baardsnes, Jason; Moraitis, Anna; Smith, Emma E.; Ali, Zahida; Berhe, Phil; Mulder, Andrew; Meibohm, Bernd; Daugherty, Bruce; Fogarty, Siobhan; Pierson, Richard N.; Lederman, Seth; Kawai, Tatsuo
Selective Bcl-2 inhibition promotes hematopoietic chimerism and allograft tolerance without myelosuppression in nonhuman primates
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2023-04-055
OA
Sasaki, Hajime; Hirose, Takayuki; Oura, Tetsu; Otsuka, Ryo; Rosales, Ivy; Ma, David; Lassiter, Grace; Karadagi, Ahmad; Tomosugi, Toshihide; Dehnadi, Abbas; Matsunami, Masatoshi; Paul, Susan Raju; Reeves, Patrick M.; Hanekamp, Isabel; Schwartz, Samuel; Colvin, Robert B.; Lee, Hang; Spitzer, Thomas R.; Cosimi, A. Benedict; Cippa, Pietro E.; Fehr, Thomas; Kawai, Tatsuo

研究方向

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H
Haruka Wada
H 指数:24论文数:105被引数:2,027
K
K. Seino
H 指数:21论文数:91被引数:1,324
H 指数:0论文数:27被引数:357
A
Ahmad Karadagi
H 指数:10论文数:40被引数:617
K
Ken‐ichiro Seino
H 指数:34论文数:187被引数:4,190
J
Junichi Yoshikawa
H 指数:70论文数:872被引数:2.0万
M
Muhammad Baghdadi
H 指数:21论文数:88被引数:2,126
T
Tatsuo Kawai
H 指数:45论文数:304被引数:1.0万
I
Ivy A. Rosales
H 指数:33论文数:220被引数:4,729
T
Toshihide Tomosugi
H 指数:12论文数:73被引数:740