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E

Elisabeth Heßmann

university medical center gottingen
H指数:26
被引数:3,159

个人简介

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荣誉奖项

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Simultaneous targeting of KRAS and CDK4 synergistically induces durable growth arrest in pancreatic cancer cells

同时靶向KRAS和CDK4协同性地诱导胰腺癌细胞产生持久的生长抑制

Cell Death & Disease
IF9.6
2025-12-230
OA
Maj-Britt Paulsohn; Klara Henrike Frahnert; Denise Schlösser; Joana Oschwald; Waltraut Kopp; Xin Fang; Carolin Schneider; Constanza Tapia Contreras; Adi Danieli-Mackay; Fabian Ludewig; Martina Bleyer; Gabriela Salinas; Günter Schneider; Elisabeth Hessmann; Matthias Dobbelstein
Targeting Mutual Dependence of Phosphatidylinositol-3-Kinase α/δ and Small Ubiquitin-Like Modifier Signaling in Pancreatic Cancer

靶向磷脂酰肌醇-3-激酶α/δ和小泛素样修饰物信号通路之间的相互依赖性在胰腺癌中的作用

Gastroenterology
IF25.1
2025-10-270
OAAI
Hazal Köse; Christian Schneeweis; Philipp Putze; Constanza Tapia Contreras; Laura Ferreiro; Leonie Witte; Ilaria Deidda; Frederik Herzberg; Sophie Ebert; Juraj Jakubik; Leoni Moldaner; Jovan Todorovic; Isabelle Träger; Chuanbing Zang; Uta M. Demel; Elisabeth Hessmann; Marieluise Kirchner; Simone Rhein; Jens Hoffmann; Zuzana Tatarova; Michael Ghadimi; Dieter Saur; Kai Kappert; Philipp Mertins; Günter Schneider; Ulrich Keller; Matthias Wirth
Glucocorticoid receptor suppresses GATA6-mediated RNA polymerase II pause release to modulate classical subtype identity in pancreatic cancer

糖皮质激素受体通过抑制GATA6介导的RNA聚合酶II暂停释放来调控胰腺癌经典亚型的身份。

GUT
IF25.8
2025-01-300
PRE
Ekstrom, Thomas L.; Rosok, Raya M.; Abdelrahman, Amro M.; Parassiadis, Christina; Manjunath, Meghana; Dittrich, Marianna Y.; Wang, Xin; Kutschat, Ana P.; Kanakan, Akshay; Rajput, Ashish; Schacherer, Nadine; Lukic, Teodora; Carlson, Danielle M.; Thiel, Julia; Kopp, Waltraut; Stroebel, Philipp; Ellenrieder, Volker; Gaedcke, Jochen; Dong, Meng; Najafova, Zeynab; Truty, Mark J.; Hessmann, Elisabeth; Johnsen, Steven A.
KRASG12C-inhibitor-based combination therapies for pancreatic cancer: insights from drug screening

胰腺癌的KRASG12C-inhibitor-based联合治疗: 来自药物筛选的见解

MOLECULAR ONCOLOGY
IF4.5
2024-09-100
OA
Contreras, Constanza Tapia; Falke, Jonas Dominik; Seifert, Dana-Magdalena; Schneider, Carolin; Krauss, Lukas; Fang, Xin; Mueller, Denise; Demirdizen, Engin; Spitzner, Melanie; De Oliveira, Tiago; Schneeweis, Christian; Gaedcke, Jochen; Kaulfuss, Silke; Mirzakhani, Kimia; Wollnik, Bernd; Conrads, Karly; Beissbarth, Tim; Salinas, Gabriela; Huegel, Jonas; Beyer, Nils; Rheinlander, Sophia; Sax, Ulrich; Wirth, Matthias; Conradi, Lena-Christin; Reichert, Maximilian; Ellenrieder, Volker; Strobel, Philipp; Ghadimi, Michael; Grade, Marian; Saur, Dieter; Hessmann, Elisabeth; Schneider, Gunter
A Novel AMPK Inhibitor Sensitizes Pancreatic Cancer Cells to Ferroptosis Induction

一种新的AMPK抑制剂使胰腺癌细胞对铁死亡诱导敏感

ADVANCED SCIENCE
IF14.1
2024-06-172
OA
Schneider, Carolin; Hilbert, Jorina; Genevaux, Franziska; Hoefer, Stefanie; Krauss, Lukas; Schicktanz, Felix; Contreras, Constanza Tapia; Jansari, Shaishavi; Papargyriou, Aristeidis; Richter, Thorsten; Alfayomy, Abdallah M.; Falcomata, Chiara; Schneeweis, Christian; Orben, Felix; Oellinger, Ruppert; Wegwitz, Florian; Boshnakovska, Angela; Rehling, Peter; Mueller, Denise; Stroebel, Philipp; Ellenrieder, Volker; Conradi, Lena; Hessmann, Elisabeth; Ghadimi, Michael; Grade, Marian; Wirth, Matthias; Steiger, Katja; Rad, Roland; Kuster, Bernhard; Sippl, Wolfgang; Reichert, Maximilian; Saur, Dieter; Schneider, Guenter
Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma (vol 21, pg 1163, 2015)

BET家族蛋白和组蛋白去乙酰化酶的联合抑制作为胰腺导管腺癌的潜在的基于表观遗传学的疗法 (第21卷，1163页，2015)

NATURE MEDICINE
IF50
2024-05-300
OA
Mazur, Pawel K.; Herner, Alexander; Mello, Stephano S.; Wirth, Matthias; Hausmann, Simone; Sanchez-Rivera, Francisco J.; Lofgren, Shane M.; Kuschma, Timo; Hahn, Stephan A.; Vangala, Deepak; Trajkovic-Arsic, Marija; Gupta, Aayush; Heid, Irina; Noeel, Peter B.; Braren, Rickmer; Erkan, Mert; Kleeff, Joerg; Sipos, Bence; Sayles, Leanne C.; Heikenwalder, Mathias; Hessmann, Elisabeth; Ellenrieder, Volker; Esposito, Irene; Jacks, Tyler; Bradner, James E.; Khatri, Purvesh; Sweet-Cordero, E. Alejandro; Attardi, Laura D.; Schmid, Roland M.; Schneider, Guenter; Sage, Julien; Siveke, Jens T.
An NFATc1/SMAD3/cJUN Complex Restricted to SMAD4-Deficient Pancreatic Cancer Guides Rational Therapies
GASTROENTEROLOGY
IF25.1
2024-02-012
PRE
Hasselluhn, Marie C.; Schloesser, Denise; Versemann, Lennart; Schmidt, Geske E.; Ulisse, Maria; Oschwald, Joana; Zhang, Zhe; Hamdan, Feda; Xiao, Harry; Kopp, Waltraut; Spitalieri, Jessica; Kellner, Christin; Schneider, Carolin; Reutlinger, Kristina; Nagarajan, Sankari; Steuber, Benjamin; Sastra, Stephen A.; Palermo, Carmine F.; Appelhans, Jennifer; Bohnenberger, Hanibal; Todorovic, Jovan; Kostyuchek, Irina; Stroebel, Philipp; Bockelmann, Aiko; Koenig, Alexander; Ammer-Herrmenau, Christoph; Schmidleitner, Laura; Kaulfuss, Silke; Wollnik, Bernd; Hahn, Stephan A.; Neesse, Albrecht; Singh, Shiv K.; Bastians, Holger; Reichert, Maximilian; Sax, Ulrich; Olive, Kenneth P.; Johnsen, Steven A.; Schneider, Guenter; Ellenrieder, Volker; Hessmann, Elisabeth
Identification of a DNp63-Dependent Basal-Like A Subtype-Specific Transcribed Enhancer Program (B-STEP) in Aggressive Pancreatic Ductal Adenocarcinoma

在侵袭性胰腺导管腺癌中鉴定DNp63-Dependent的基底样a亚型特异性转录增强子程序 (b-step)

MOLECULAR CANCER RESEARCH
IF4.7
2023-06-062
OA
Wang, Xin; Kutschat, Ana P.; Aggrey-Fynn, Joana; Hamdan, Feda H.; Graham, Rondell P.; Wixom, Alexander Q.; Souto, Yara; Ladigan-Badura, Swetlana; Yonkus, Jennifer A.; Abdelrahman, Amro M.; Alva-Ruiz, Roberto; Gaedcke, Jochen; Stroebel, Philipp; Kosinsky, Robyn Laura; Wegwitz, Florian; Hermann, Patrick; Truty, Mark J.; Siveke, Jens T.; Hahn, Stephan A.; Hessmann, Elisabeth; Johnsen, Steven A.; Najafova, Zeynab
NFATc1 Is a Central Mediator of EGFR-Induced ARID1A Chromatin Dissociation During Acinar Cell Reprogramming

NFATc1是腺泡细胞重编程过程中EGFR诱导的ARID1A染色质解离的中心介质

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY
IF7.4
2023-01-014
OAAI
Zhang, Zhe; Wang, Xin; Hamdan, Feda H.; Likhobabina, Anna; Patil, Shilpa; Aperdannier, Lena; Sen, Madhobi; Traub, Jacobe; Neesse, Albrecht; Fischer, Andre; Papantonis, Argyris; Singh, Shiv K.; Ellenrieder, Volker; Johnsen, Steven A.; Hessmann, Elisabeth
Axon guidance receptor ROBO3 modulates subtype identity and prognosis via AXL-associated inflammatory network in pancreatic cancer
JCI INSIGHT
IF6.1
2022-08-226
OA
Krebs, Niklas; Klein, Lukas; Wegwitz, Florian; Espinet, Elisa; Maurer, Hans Carlo; Tu, Mengyu; Penz, Frederike; Kueffer, Stefan; Xu, Xingbo; Bohnenberger, Hanibal; Cameron, Silke; Brunner, Marius; Neesse, Albrecht; Kishore, Uday; Hessmann, Elisabeth; Trumpp, Andreas; Stroebel, Philipp; Brekken, Rolf A.; Ellenrieder, Volker; Singh, Shiv K.

研究方向

暂未获取到该数据
P
Philipp Ströbel
H 指数:64论文数:613被引数:1.5万
A
Albrecht Neeße
H 指数:40论文数:366被引数:8,851
S
Shiv K. Singh
H 指数:26论文数:131被引数:2,689
V
Volker Ellenrieder
H 指数:30论文数:277被引数:3,563
J
Jochen Gaedcke
H 指数:46论文数:471被引数:7,456
V
Volker Ellenrieder
H 指数:27论文数:175被引数:3,244
G
Günter Schneider
H 指数:53论文数:240被引数:1.0万
J
Jens T. Siveke
H 指数:62论文数:743被引数:1.4万
S
Steven A. Johnsen
H 指数:50论文数:447被引数:7,077
J
Jin‐San Zhang
H 指数:44论文数:198被引数:6,250