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M

Mark T. Esser

AstraZeneca
H指数:55
被引数:1.4万

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Immunogenicity and efficacy of an mRNA vaccine expressing a virus-like particle spike antigen against SARS-CoV-2

针对SARS-CoV-2的、表达病毒样颗粒刺突抗原的mRNA疫苗的免疫原性和有效性

npj Vaccines
IF6.5
2025-12-130
OAAI
Jason P. Laliberte; Yingyun Cai; Tara Kenny; Yi Zhang; Kuishu Ren; Kim Rosenthal; Daniel Flores; Richard Roque; Oliver Acton; Vanessa Cadevilla Peano; Noel Janney; Vinita Puri; Sarah Siddiqui; Angela Pack; Giune Padilla; Seme Diallo; Hibret Adissu; Rakesh Choudhary; Hawley Pruitt; Yi-Han Cheng; George Thom; Michael Newton; Cheyne Kurokawa; Johnathan Guest; Phillip Swanson; Yueh-Ming Loo; Joseph R. Francica; Wade Blair; Mark Esser
Safety and pharmacokinetics of SARS-CoV-2 DNA-encoded monoclonal antibodies in healthy adults: a phase 1 trial

SARS-CoV-2 DNA编码单克隆抗体的安全性与药代动力学：一项1期临床试验

Nature Medicine
IF50
2025-10-210
OAAI
Pablo Tebas; Ami Patel; Joseph T. Agnes; Elizabeth M. Parzych; Amanda Baer; Maria Caturla; Sukanya Ghosh; Mansi Purwar; Nicole Bedanova; Chungdhak Tsang; Knashawn Morales; Dinah Amante; Paul D. Fisher; Joseph R. Francica; Laurent Humeau; Daniel W. Kulp; Jesper Pallesen; Paul Leon; Mark Esser; Trevor R. F. Smith; David B. Weiner
A SARS-CoV-2 variant‑adjusted threshold of protection model for monoclonal antibody pre-exposure prophylaxis against COVID-19

针对COVID-19的单克隆抗体暴露前预防的保护阈值模型（SARS-CoV-2变体调整）

Nature Communications
IF15.7
2025-10-140
OAAI
Rhiannon Edge; Sam Matthews; Bahar Ahani; Anastasia A. Aksyuk; Lindsay Clegg; John L. Perez; Mark T. Esser; Lee-Jah Chang; Ian Hirsch; Tonya Villafana; John Pura; Oleg Stepanov; Katie Streicher; Tom White; Taylor S. Cohen; Dean Follmann; Peter B. Gilbert; Seth Seegobin
Impact of Pseudomonas aeruginosa carriage on intensive care unit- acquired pneumonia: a European multicentre prospective cohort study

铜绿假单胞菌携带对重症监护室获得性肺炎的影响：一项欧洲多中心前瞻性队列研究

CLINICAL MICROBIOLOGY AND INFECTION
IF8.5
2025-03-010
PRE
Recanatini, C.; van Werkhoven, C. H.; van der Schalk, T. E.; Paling, F.; Hazard, D.; Timbermont, L.; Torrens, G.; Digiandomenico, A.; Esser, M. T.; Wolkewitz, M.; Sifakis, F.; Goossens, H.; Bonten, M.; Oliver, A.; Malhotra-Kumar, S.; Kluytmans, J.
Pre-exposure antibody prophylaxis protects macaques from severe influenza

暴露前抗体预防可保护猕猴免受严重流感的侵害

Science
IF45.8
2025-01-010
PRE
Masaru Kanekiyo; Rebecca A. Gillespie; Kristine L. Cooper; Vanessa I. Guerra; Priscila M. S. Castanha; Amarendra Pegu; Eun Sung Yang; Luke Treaster; Gabin Yun; Megan Wallace; Gwenddolen Kettenburg; Connor Williams; Jeneveve D. Lundy; Stacey Barrick; Katherine J. O’Malley; Morgan Midgett; Michelle M. Martí; Hasitha Chavva; Jacqueline Corry; Benjamin R. Treat; Abby L Lipinski; Lucía Ortiz; Adrian Creanga; Isabella Ritter; Reagan C. Walker; Emily L. Olsen; Amanda Laughlin; Daniel Roberto Perez; John R. Mascola; Eli Boritz; Yueh–Ming Loo; Wade S. Blair; Mark Thomas Esser; Barney S. Graham; Douglas S. Reed; Simon M. Barratt‐Boyes
Lower Respiratory Tract Infections Following Respiratory Syncytial Virus Monoclonal Antibody Nirsevimab Immunization Versus Placebo: Analysis From a Phase 3 Randomized Clinical Trial (MELODY)

呼吸道合胞病毒单克隆抗体Nirsevimab预防接种与安慰剂后的下呼吸道感染: 一项3期随机临床试验 (MELODY) 的分析

CLINICAL INFECTIOUS DISEASES
IF7.3
2024-12-041
OAAI
Arbetter, Doug; Gopalakrishnan, Vancheswaran; Aksyuk, Anastasia A.; Ahani, Bahar; Chang, Yue; Dagan, Ron; Esser, Mark T.; Hammitt, Laura L.; Mankad, Vaishali S.; Saez-Llorens, Xavier; Shen, David; Leach, Amanda; Kelly, Elizabeth J.; Villafana, Tonya; Wilkins, Deidre
AZD3152 neutralizes SARS-CoV-2 historical and contemporary variants and is protective in hamsters and well tolerated in adults
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2024-06-261
PRE
Cai, Yingyun; Diallo, Seme; Rosenthal, Kim; Ren, Kuishu; Flores, Daniel J.; Dippel, Andrew; Oganesyan, Vaheh; van Dyk, Nydia; Chen, Xiaoru; Cantu, Erin; Choudhary, Rakesh; Sulikowski, Michal; Adissu, Hibret; Chawla, Bhavna; Kar, Swagata; Liu, Chang; Dijokaite-Guraliuc, Aiste; Mongkolsapaya, Juthathip; Rajan, Saravanan; Loo, Yueh-Ming; Beavon, Rohini; Webber, Chris; Chang, Lee-Jah; Thomas, Steven; Clegg, Lindsay; Zhang, Huixia; Screaton, Gavin R.; Philbin, Nora; Harre, Mark; Selim, Abdulhafez; Martinez-Alier, Nuria; Uriel, Alison; Cohen, Taylor S.; Perez, John L.; Esser, Mark T.; Blair, Wade; Francica, Joseph R.
Accelerating therapeutics development during a pandemic: population pharmacokinetics of the long-acting antibody combination AZD7442 (tixagevimab/cilgavimab) in the prophylaxis and treatment of COVID-19

在大流行期间加速治疗药物的开发: 长效抗体组合AZD7442 (tixagevimab/cilgavimab) 在预防和治疗新型冠状病毒肺炎中的群体药代动力学

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
2024-05-023
OAAI
Clegg, Lindsay E.; Stepanov, Oleg; Schmidt, Henning; Tang, Weifeng; Zhang, Huixia; Webber, Chris; Cohen, Taylor S.; Esser, Mark T.; Nagard, Mats
In vivo delivery of engineered synthetic DNA-encoded SARS-CoV-2 monoclonal antibodies for pre-exposure prophylaxis in non-human primates
EMERGING MICROBES & INFECTIONS
IF7.5
2024-02-280
OAAI
Patel, Ami; Rosenke, Kyle; Parzych, Elizabeth M.; Feldmann, Friederike; Bharti, Suman; Griffin, Amanda J.; Schouest, Blake; Lewis, Matt; Choi, Jihae; Chokkalingam, Neethu; Machado, Viviane; Smith, Brian J.; Frase, Drew; Ali, Ali R.; Lovaglio, Jamie; Nguyen, Brian; Hanley, Patrick W.; Walker, Susanne N.; Gary, Ebony N.; Kulkarni, Abhijeet; Generotti, Allison; Francica, Joseph R.; Rosenthal, Kim; Kulp, Daniel W.; Esser, Mark T.; Smith, Trevor R. F.; Shaia, Carl; Weiner, David B.; Feldmann, Heinz
Nirsevimab binding-site conservation in respiratory syncytial virus fusion glycoprotein worldwide between 1956 and 2021: an analysis of observational study sequencing data
LANCET INFECTIOUS DISEASES
IF31
2023-07-0135
PRE
Wilkins, Deidre; Langedijk, Annefleur C.; Lebbink, Robert Jan; Morehouse, Christopher; Abram, Michael E.; Ahani, Bahar; Aksyuk, Anastasia A.; Baraldi, Eugenio; Brady, Tyler; Chen, Albert Tian; Chi, Hsin; Choi, Eun Hwa; Cohen, Robert; Danilenko, Daria M.; Gopalakrishnan, Vancheswaran; Greenough, Anne; Heikkinen, Terho; Hosoya, Mitsuaki; Keller, Christian; Kelly, Elizabeth J.; Kragten-Tabatabaie, Leyla; Martinon-Torres, Federico; de los Santos, Abiel Homero Mascarenas; Nunes, Marta C.; Palomino, Maria Angelica; Papenburg, Jesse; Pernica, Jeffrey M.; Richmond, Peter; Stein, Renato; Tuffy, Kevin M.; Verwey, Charl; Esser, Mark T.; Tabor, David E.; Bont, Louis J.
Safety, Tolerability and Pharmacokinetics of Half-Life Extended Severe Acute Respiratory Syndrome Coronavirus 2 Neutralizing Monoclonal Antibodies AZD7442 (Tixagevimab-Cilgavimab) in Healthy Adults

半衰期延长的新型冠状病毒中和单克隆抗体AZD7442 (tixagevimab-cilgavimab) 在健康成人中的安全性，耐受性和药代动力学

JOURNAL OF INFECTIOUS DISEASES
IF4.5
2023-01-2312
OAAI
Forte-Soto, Pablo; Albayaty, Muna; Brooks, Dennis; Arends, Rosalinda H.; Tillinghast, John; Aksyuk, Anastasia A.; Bouquet, Jerome; Chen, Cecil; Gebre, Asfiha; Kubiak, Robert J.; Reddy, Venkatesh Pilla; Seegobin, Seth; Streicher, Katie; Templeton, Alison; Esser, Mark T.
A prefusion-stabilized RSV F subunit vaccine elicits B cell responses with greater breadth and potency than a postfusion F vaccine

融合前稳定的RSV F亚单位疫苗比融合后F疫苗引起的b细胞反应具有更大的广度和效力

SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2022-12-2119
OA
Chang, Lauren A.; Phung, Emily; Crank, Michelle C.; Morabito, Kaitlyn M.; Villafana, Tonya; Dubovsky, Filip; Falloon, Judith; Esser, Mark T.; Lin, Bob C.; Chen, Grace L.; Graham, Barney S.; Ruckwardt, Tracy J.
Developability profiling of a panel of Fc engineered SARS-CoV-2 neutralizing antibodies
MABS
IF7.3
2022-12-085
OAAI
Dippel, Andrew; Gallegos, Austin; Aleti, Vineela; Barnes, Arnita; Chen, Xiaoru; Christian, Elizabeth; Delmar, Jared; Du, Qun; Esfandiary, Reza; Farmer, Erika; Garcia, Andrew; Li, Qing; Lin, Jia; Liu, Weiyi; Machiesky, LeeAnn; Mody, Neil; Parupudi, Arun; Prophet, Meagan; Rickert, Keith; Rosenthal, Kim; Ren, Song; Shandilya, Harini; Varkey, Reena; Wons, Kevin; Wu, Yuling; Loo, Yueh-Ming; Esser, Mark T. T.; Kallewaard, Nicole L. L.; Rajan, Sarav; Damschroder, Melissa; Xu, Weichen; Kaplan, Gilad
Safety and Efficacy of MEDI0457 plus Durvalumab in Patients with Human Papillomavirus-Associated Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
CLINICAL CANCER RESEARCH
IF10.2
2022-12-0114
OAAI
Aggarwal, Charu; Saba, Nabil F.; Algazi, Alain; Sukari, Ammar; Seiwert, Tanguy Y.; Haigentz, Missak; Porosnicu, Mercedes; Bonomi, Marcelo; Boyer, Jean; Esser, Mark T.; Cheng, Lily I.; Agrawal, Sonia; Jennings, Emily C.; Durham, Nicholas M.; Fraser, Karl; Lissa, Delphine; Gong, Maozhen; Ceaicovscaia, Natalia; Hernandez, Amaya Gasco; Kumar, Rakesh
Gut to lung translocation and antibiotic mediated selection shape the dynamics of Pseudomonas aeruginosa in an ICU patient

肠向肺易位和抗生素介导的选择塑造了ICU患者铜绿假单胞菌的动力学

NATURE COMMUNICATIONS
IF15.7
2022-11-2235
OAAI
Wheatley, Rachel M.; Caballero, Julio Diaz; van der Schalk, Thomas E.; De Winter, Fien H. R.; Shaw, Liam P.; Kapel, Natalia; Recanatini, Claudia; Timbermont, Leen; Kluytmans, Jan; Esser, Mark; Lacoma, Alicia; Prat-Aymerich, Cristina; Oliver, Antonio; Kumar-Singh, Samir; Malhotra-Kumar, Surbhi; MacLean, R. Craig
AZD7442 (Tixagevimab/Cilgavimab) for Post-Exposure Prophylaxis of Symptomatic Coronavirus Disease 2019

AZD7442 (Tixagevimab/Cilgavimab) 用于症状性冠状病毒疾病的暴露后预防2019

CLINICAL INFECTIOUS DISEASES
IF7.3
2022-11-2228
OAAI
Levin, Myron J.; Ustianowski, Andrew; Thomas, Steven; Templeton, Alison; Yuan, Yuan; Seegobin, Seth; Houlihan, Catherine F.; Menendez-Perez, Ibrahim; Pollett, Simon; Arends, Rosalinda H.; Beavon, Rohini; Dey, Kanika; Garbes, Pedro; Kelly, Elizabeth J.; Koh, Gavin C. K. W.; Ivanov, Stefan; Near, Karen A.; Sharbaugh, Audrey; Streicher, Katie; Pangalos, Menelas N.; Esser, Mark T.

研究方向

暂未获取到该数据
T
Tonya Villafana
H 指数:38论文数:88被引数:1.4万
D
David E. Tabor
H 指数:32论文数:66被引数:1.8万
D
Deidre Wilkins
H 指数:22论文数:49被引数:1,427
A
Alexey Ruzin
H 指数:34论文数:108被引数:4,020
Y
Yueh–Ming Loo
H 指数:39论文数:81被引数:1.4万
H
Hasan S. Jafri
H 指数:47论文数:105被引数:7,527
K
Kim Rosenthal
H 指数:14论文数:42被引数:951
M
Michael E. Abram
H 指数:35论文数:85被引数:5,464
J
Janine T. Bryan
H 指数:44论文数:94被引数:1.1万
A
Anastasia A. Aksyuk
H 指数:16论文数:46被引数:1,474