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收藏分享 收藏 PLK1 blockade enhances the anti-tumor effect of MAPK inhibition in pancreatic ductal adenocarcinomaPLK1阻断增强了MAPK抑制在胰腺导管腺癌中的抗肿瘤效果
Zhao, Ben; Fang, Rui; Schuermann, Hendrik; Hemmer, Erik Jan; Mayer, Gina Lauren; Trajkovic-Arsic, Marija; Althoff, Kristina; Yang, Jiajin; Godfrey, Laura; Liffers, Sven T.; Savvatakis, Konstantinos; Dorsch, Madeleine; Gruener, Barbara M.; Hahn, Stephan; Remke, Marc; Lueong, Smiths S.; Siveke, Jens T. 分享 收藏 Pouch Fistulas: Experience From a Tertiary CenterBronze, S. M. Tubal; Wong, S. Y.; Waite, H.; Plietz, M.; Hahn, S.; Greenstein, A.; Sylla, P.; Khaitov, S.; Colombel, J. F.; Kayal, M. 分享 收藏 Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma (vol 21, pg 1163, 2015)BET家族蛋白和组蛋白去乙酰化酶的联合抑制作为胰腺导管腺癌的潜在的基于表观遗传学的疗法 (第21卷，1163页，2015)Mazur, Pawel K.; Herner, Alexander; Mello, Stephano S.; Wirth, Matthias; Hausmann, Simone; Sanchez-Rivera, Francisco J.; Lofgren, Shane M.; Kuschma, Timo; Hahn, Stephan A.; Vangala, Deepak; Trajkovic-Arsic, Marija; Gupta, Aayush; Heid, Irina; Noeel, Peter B.; Braren, Rickmer; Erkan, Mert; Kleeff, Joerg; Sipos, Bence; Sayles, Leanne C.; Heikenwalder, Mathias; Hessmann, Elisabeth; Ellenrieder, Volker; Esposito, Irene; Jacks, Tyler; Bradner, James E.; Khatri, Purvesh; Sweet-Cordero, E. Alejandro; Attardi, Laura D.; Schmid, Roland M.; Schneider, Guenter; Sage, Julien; Siveke, Jens T. 分享 收藏 An NFATc1/SMAD3/cJUN Complex Restricted to SMAD4-Deficient Pancreatic Cancer Guides Rational TherapiesHasselluhn, Marie C.; Schloesser, Denise; Versemann, Lennart; Schmidt, Geske E.; Ulisse, Maria; Oschwald, Joana; Zhang, Zhe; Hamdan, Feda; Xiao, Harry; Kopp, Waltraut; Spitalieri, Jessica; Kellner, Christin; Schneider, Carolin; Reutlinger, Kristina; Nagarajan, Sankari; Steuber, Benjamin; Sastra, Stephen A.; Palermo, Carmine F.; Appelhans, Jennifer; Bohnenberger, Hanibal; Todorovic, Jovan; Kostyuchek, Irina; Stroebel, Philipp; Bockelmann, Aiko; Koenig, Alexander; Ammer-Herrmenau, Christoph; Schmidleitner, Laura; Kaulfuss, Silke; Wollnik, Bernd; Hahn, Stephan A.; Neesse, Albrecht; Singh, Shiv K.; Bastians, Holger; Reichert, Maximilian; Sax, Ulrich; Olive, Kenneth P.; Johnsen, Steven A.; Schneider, Guenter; Ellenrieder, Volker; Hessmann, Elisabeth 分享 收藏 分享 收藏 Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progenitorsMavrommatis, Lampros; Jeong, Hyun-Woo; Kindler, Urs; Gomez-Giro, Gemma; Kienitz, Marie-Cecile; Stehling, Martin; Psathaki, Olympia E.; Zeuschner, Dagmar; Bixel, M. Gabriele; Han, Dong; Morosan-Puopolo, Gabriela; Gerovska, Daniela; Yang, Ji Hun; Kim, Jeong Beom; Arauzo-Bravo, Marcos J.; Schwamborn, Jens C.; Hahn, Stephan A.; Adams, Ralf H.; Scholer, Hans R.; Vorgerd, Matthias; Brand-Saberi, Beate; Zaehres, Holm 分享 收藏 Coinhibition of topoisomerase 1 and BRD4-mediated pause release selectively kills pancreatic cancer via readthrough transcriptionCameron, Donald P.; Grosser, Jan; Ladigan, Swetlana; Kuzin, Vladislav; Iliopoulou, Evanthia; Wiegard, Anika; Benredjem, Hajar; Jackson, Kathryn; Liffers, Sven T.; Lueong, Smiths; Cheung, Phyllis F.; Vangala, Deepak; Pohl, Michael; Viebahn, Richard; Teschendorf, Christian; Wolters, Heiner; Usta, Selami; Geng, Keyi; Kutter, Claudia; Arsenian-Henriksson, Marie; Siveke, Jens T.; Tannapfel, Andrea; Schmiegel, Wolff; Hahn, Stephan A.; Baranello, Laura 分享 收藏 Lasting response by vertical inhibition with cetuximab and trametinib in KRAS-mutated colorectal cancer patient-derived xenograftsReissig, Timm M.; Ladigan-Badura, Swetlana; Steinberg, Anja; Maghnouj, Abdelouahid; Li, Ting; Verdoodt, Berlinda; Liffers, Sven T.; Pohl, Michael; Wolters, Heiner; Teschendorf, Christian; Viebahn, Richard; Admard, Jakob; Casadei, Nicolas; Tannapfel, Andrea; Schmiegel, Wolff; Hahn, Stephan A.; Vangala, Deepak B. 分享 收藏 Identification of a DNp63-Dependent Basal-Like A Subtype-Specific Transcribed Enhancer Program (B-STEP) in Aggressive Pancreatic Ductal Adenocarcinoma在侵袭性胰腺导管腺癌中鉴定DNp63-Dependent的基底样a亚型特异性转录增强子程序 (b-step)Wang, Xin; Kutschat, Ana P.; Aggrey-Fynn, Joana; Hamdan, Feda H.; Graham, Rondell P.; Wixom, Alexander Q.; Souto, Yara; Ladigan-Badura, Swetlana; Yonkus, Jennifer A.; Abdelrahman, Amro M.; Alva-Ruiz, Roberto; Gaedcke, Jochen; Stroebel, Philipp; Kosinsky, Robyn Laura; Wegwitz, Florian; Hermann, Patrick; Truty, Mark J.; Siveke, Jens T.; Hahn, Stephan A.; Hessmann, Elisabeth; Johnsen, Steven A.; Najafova, Zeynab 分享 收藏 Functional noninvasive detection of glycolytic pancreatic ductal adenocarcinoma糖酵解性胰腺导管腺癌的功能性无创检测Heid, Irina; Muench, Corinna; Karakaya, Sinan; Lueong, Smiths S.; Winkelkotte, Alina M.; Liffers, Sven T.; Godfrey, Laura; Cheung, Phyllis F. Y.; Savvatakis, Konstantinos; Topping, Geoffrey J.; Englert, Florian; Kritzner, Lukas; Grashei, Martin; Tannapfel, Andrea; Viebahn, Richard; Wolters, Heiner; Uhl, Waldemar; Vangala, Deepak; Smeets, Esther M. M.; Aarntzen, Erik H. J. G.; Rauh, Daniel; Weichert, Wilko; Hoheisel, Joerg D.; Hahn, Stephan A.; Schilling, Franz; Braren, Rickmer; Trajkovic-Arsic, Marija; Siveke, Jens T. 分享 收藏 De novo expression of gastrokines in pancreatic precursor lesions impede the development of pancreatic cancerSteiner, Sabrina; Seleznik, Gitta M.; Reding, Theresia; Stopic, Matea; Lenggenhager, Daniela; ten Buren, Emiel; Eshmuminov, Dilmurodjon; Endhardt, Katharina; Hagedorn, Catherine; Heidenblut, Anna M.; Bratus-Neuenschwander, Anna; Grossmann, Jonas; Trachsel, Christian; Jabbar, Karolina S.; Hahn, Stephan A.; vom Berg, Johannes; Graf, Rolf; Gupta, Anurag 分享 收藏 TNF-α-producing macrophages determine subtype identity and prognosis via AP1 enhancer reprogramming in pancreatic cancerTu, Mengyu; Klein, Lukas; Espinet, Elisa; Georgomanolis, Theodoros; Wegwitz, Florian; Li, Xiaojuan; Urbach, Laura; Danieli-Mackay, Adi; Kueffer, Stefan; Bojarczuk, Kamil; Mizi, Athanasia; Guenesdogan, Ufuk; Chapuy, Bjoern; Gu, Zuguang; Neesse, Albrecht; Kishore, Uday; Stroebel, Philipp; Hessmann, Elisabeth; Hahn, Stephan A.; Trumpp, Andreas; Papantonis, Argyris; Ellenrieder, Volker; Singh, Shiv K. 分享 收藏 Secondary resistance to anti-EGFR therapy by transcriptional reprogramming in patient-derived colorectal cancer modelsVangala, Deepak; Ladigan, Swetlana; Liffers, Sven T.; Noseir, Soha; Maghnouj, Abdelouahid; Gotze, Tina-Maria; Verdoodt, Berlinda; Klein-Scory, Susanne; Godfrey, Laura; Zowada, Martina K.; Huerta, Mario; Edelstein, Daniel L.; de Villarreal, Jaime Martinez; Marques, Miriam; Kumbrink, Jorg; Jung, Andreas; Schiergens, Tobias; Werner, Jens; Heinemann, Volker; Stintzing, Sebastian; Lindoerfer, Doris; Mansmann, Ulrich; Pohl, Michael; Teschendorf, Christian; Bernhardt, Christiane; Wolters, Heiner; Stern, Josef; Usta, Selami; Viebahn, Richard; Admard, Jacob; Casadei, Nicolas; Frohling, Stefan; Ball, Claudia R.; Siveke, Jens T.; Glimm, Hanno; Tannapfel, Andrea; Schmiegel, Wolff; Hahn, Stephan A. 分享 收藏 Deficiency of myostatin protects skeletal muscle cells from ischemia reperfusion injuryWallner, Christoph; Drysch, Marius; Becerikli, Mustafa; Schmidt, Sonja Verena; Hahn, Stephan; Wagner, Johannes Maximilian; Reinkemeier, Felix; Dadras, Mehran; Sogorski, Alexander; von Glinski, Maxi; Lehnhardt, Marcus; Behr, Bjoern 分享 收藏 Altered T-Lymphocyte Biology Following High-Dose Melphalan and Autologous Stem Cell Transplantation With Implications for Adoptive T-Cell TherapyMika, Thomas; Ladigan-Badura, Swetlana; Maghnouj, Abdelouahid; Mustafa, Bakr; Klein-Scory, Susanne; Baraniskin, Alexander; Doehring, Sascha; Fuchs, Ilka; Ehl, Stephan; Hahn, Stephan A.; Schroers, Roland 分享 收藏 分享 收藏 Characterization of a dualBET/HDACinhibitor for treatment of pancreatic ductal adenocarcinoma用于治疗胰腺导管腺癌的dualBET/hdac抑制剂的表征Zhang, Xin; Zegar, Tim; Weiser, Tim; Hamdan, Feda H.; Berger, Benedict-Tilman; Lucas, Romain; Balourdas, Dimitrios-IIias; Ladigan, Swetlana; Cheung, Phyllis F.; Liffers, Sven-Thorsten; Trajkovic-Arsic, Marija; Scheffler, Bjoern; Joerger, Andreas C.; Hahn, Stephan A.; Johnsen, Steven A.; Knapp, Stefan; Siveke, Jens T. 分享 收藏 Digital-Droplet PCR for Quantification of CD19-Directed CAR T-CellsMika, Thomas; Maghnouj, Abdelouahid; Klein-Scory, Susanne; Ladigan-Badura, Swetlana; Baraniskin, Alexander; Thomson, Julia; Hasenkamp, Justin; Hahn, Stephan A.; Wulf, Gerald; Schroers, Roland 分享 收藏 
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