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Melatonin protects aged oocytes from depalmitoylation-mediated quality reduction by promoting PPT1 degradation and antioxidation 褪黑素通过促进PPT1降解和抗氧化作用，保护老化卵母细胞免受去棕榈酰化介导的质量下降。 Ma, Rujun; Xue, Mengqi; Ge, Feiyan; Jueraitetibaike, Kadiliya; Zhao, Shanmeizi; Qian, Zhang; He, Zhaowanyue; Zhang, Hong; Tang, Ting; Cao, Chun; Li, Chuwei; Zheng, Lu; Xue, Tongmin; Dong, Jie; Jing, Jun; Zhong, Jian; Ma, Jinzhao; Yang, Yang; Huang, Yadong; Ge, Xie; Yao, Bing; Chen, Li 分享 收藏
Riluzole Reverses Blood-Testis Barrier Loss to Rescue Chemotherapy-Induced Male Infertility by Binding to TRPC 利鲁唑通过与TRPC结合逆转血液-睾丸屏障丧失以挽救化疗引起的男性不育症 Huang, Rufei; Xia, Huan; Lin, Wanqing; Wang, Zhaoyang; Li, Lu; Deng, Jingxian; Ye, Tao; Li, Ziyi; Yang, Yan; Huang, Yadong 分享 收藏
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Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference APOE和痴呆症研究的进展: 2023 AAIC进展的亮点: APOE会议 Kloske, Courtney M.; Belloy, Michael E.; Blue, Elizabeth E.; Bowman, Gregory R.; Carrillo, Maria C.; Chen, Xiaoying; Chiba-Falek, Ornit; Davis, Albert A.; Di Paolo, Gilbert; Garretti, Francesca; Gate, David; Golden, Lesley R.; Heinecke, Jay W.; Herz, Joachim; Huang, Yadong; Iadecola, Costantino; Johnson, Lance A.; Kanekiyo, Takahisa; Karch, Celeste M.; Khvorova, Anastasia; Koppes-den Hertog, Sascha J.; Lamb, Bruce T.; Lawler, Paige E.; Guen, Yann Le; Litvinchuk, Alexandra; Liu, Chia-Chen; Mahinrad, Simin; Marcora, Edoardo; Marino, Claudia; Michaelson, Danny M.; Miller, Justin J.; Morganti, Josh M.; Narayan, Priyanka S.; Naslavsky, Michel S.; Oosthoek, Marlies; Ramachandran, Kapil V.; Ramakrishnan, Abhirami; Raulin, Ana-Caroline; Robert, Aiko; Saleh, Rasha N. M.; Sexton, Claire; Shah, Nilomi; Shue, Francis; Sible, Isabel J.; Soranno, Andrea; Strickland, Michael R.; Julia, T. C. W.; Thierry, Manon; Tsai, Li-Huei; Tuckey, Ryan A.; Ulrich, Jason D.; van der Kant, Rik; Wang, Na; Wellington, Cheryl L.; Weninger, Stacie C.; Yassine, Hussein N.; Zhao, Na; Bu, Guojun; Goate, Alison M.; Holtzman, David M. 分享 收藏
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Report of the APOE4 National Institute on Aging/Alzheimer Disease Sequencing Project Consortium Working Group: Reducing APOE4 in Carriers is a Therapeutic Goal for Alzheimer's Disease APOE4美国国立老化研究所/阿尔茨海默病测序项目联盟工作组报告：降低携带者体内的APOE4水平是阿尔茨海默病的治疗目标 Vance, Jeffery M.; Farrer, Lindsay A.; Huang, Yadong; Cruchaga, Carlos; Hyman, Bradley T.; Pericak-Vance, Margaret A.; Goate, Alison M.; Greicius, Michael D.; Griswold, Anthony J.; Haines, Jonathan L.; Julia, T. C. W.; Schellenberg, Gerard D.; Tsai, Li-Huei; Herz, Joachim; Holtzman, David M. 分享 收藏
APOE Christchurch-mimetic therapeutic antibody reduces APOE-mediated toxicity and tau phosphorylation Marino, Claudia; Perez-Corredor, Paula; O'Hare, Michael; Heuer, Annie; Chmielewska, Natalia; Gordon, Harper; Chandrahas, Anita S.; Gonzalez-Buendia, Lucia; Delgado-Tirado, Santiago; Doan, Tri H.; Vanderleest, Timothy E.; Arevalo-Alquichire, Said; Obar, Robert A.; Ortiz-Cordero, Carolina; Villegas, Andres; Sepulveda-Falla, Diego; Kim, Leo A.; Lopera, Francisco; Mahley, Robert; Huang, Yadong; Quiroz, Yakeel T.; Arboleda-Velasquez, Joseph F. 分享 收藏
APOE4-promoted gliosis and degeneration in tauopathy are ameliorated by pharmacological inhibition of HMGB1 release Koutsodendris, Nicole; Blumenfeld, Jessica; Agrawal, Ayushi; Traglia, Michela; Yip, Oscar; Rao, Antara; Kim, Min Joo; Nelson, Maxine R.; Wang, Yung-Hua; Grone, Brian; Hao, Yanxia; Thomas, Reuben; Zilberter, Misha; Yoon, Seo Yeon; Arriola, Patrick; Huang, Yadong 分享 收藏
Neurons require glucose uptake and in vivo Li, Huihui; Guglielmetti, Caroline; Sei, Yoshitaka J.; Zilberter, Misha; Le Page, Lydia M.; Shields, Lauren; Yang, Joyce; Nguyen, Kevin; Tiret, Brice; Gao, Xiao; Bennett, Neal; Lo, Iris; Dayton, Talya L.; Kampmann, Martin; Huang, Yadong; Rathmell, Jeffrey C.; Vander Heiden, Matthew; Chaumeil, Myriam M.; Nakamura, Ken 分享 收藏
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Neuronal APOE4 removal protects against tau-mediated gliosis, neurodegeneration and myelin deficits Koutsodendris, Nicole; Blumenfeld, Jessica; Agrawal, Ayushi; Traglia, Michela; Grone, Brian; Zilberter, Misha; Yip, Oscar; Rao, Antara; Nelson, Maxine R.; Hao, Yanxia; Thomas, Reuben; Yoon, Seo Yeon; Arriola, Patrick; Huang, Yadong 分享 收藏
Bioinformatics Analysis of Publicly Available Single-Nuclei Transcriptomics Alzheimer's Disease Datasets Reveals APOE Genotype-Specific Changes Across Cell Types in Two Brain Regions 对公开可用的单核转录组学阿尔茨海默病数据集的生物信息学分析揭示了两个大脑区域中跨细胞类型的APOE基因型特异性变化 Belonwu, Stella A.; Li, Yaqiao; Bunis, Daniel G.; Rao, Arjun Arkal; Solsberg, Caroline Warly; Oskotsky, Tomiko; Taubes, Alice L.; Grone, Brian; Zalocusky, Kelly A.; Fragiadakis, Gabriela K.; Huang, Yadong; Sirota, Marina 分享 收藏
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Extracellular vesicles derived from astrocyte-treated with haFGF14-154 attenuate Alzheimer phenotype in AD mice Peng, Dong; Wang, Youjin; Xiao, Yuanjie; Peng, Mengyuan; Mai, Wanwen; Hu, Bo; Jia, Yanbin; Chen, Hongxia; Yang, Yan; Xiang, Qi; Su, Zhijian; Zhang, Qihao; Huang, Yadong 分享 收藏
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