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Pathologic complete response (pCR) rates for patients with HRD/HER2L high-risk, early-stage breast cancer (EBC) by clinical and molecular features in the phase II I-SPY2 clinical trial 在I-SPY2临床试验中，根据临床和分子特征，HRD/HER2L高风险早期乳腺癌（EBC）患者的病理完全缓解（pCR）率。 Huppert, L. A.; Wolf, D.; Yau, C.; Brown-Swigart, L.; Hirst, G. L.; Isaacs, C.; Pusztai, L.; Pohlmann, P. R.; Demichele, A.; Shatsky, R.; Yee, D.; Thomas, A.; Nanda, R.; Perlmutter, J.; Heditsian, D.; Hylton, N.; Symmans, F.; van't Veer, L. J.; Esserman, L.; Rugo, H. S. 分享 收藏
Intratumoral Injection of mRNA-2752 and Pembrolizumab for High-Risk Ductal Carcinoma In Situ A Phase 1 Nonrandomized Clinical Trial mRNA-2752和Pembrolizumab瘤内注射治疗高危导管原位癌：一项1期非随机临床试验 Ramalingam, Kirithiga; Woody, Rachel; Glencer, Alexa; Schwartz, Christopher J.; Mori, Hidetoshi; Wong, Jasmine; Hirst, Gillian; Rosenbluth, Jennifer; Onishi, Natsuko; Gibbs, Jessica; Hylton, Nola; Borowsky, Alexander D.; Campbell, Michael; Esserman, Laura J. 分享 收藏
Pexidartinib and standard neoadjuvant therapy in the adaptively randomized I-SPY2 trial for early breast cancer Rugo, Hope S.; Campbell, Mike; Yau, Christina; Jo Chien, A.; Wallace, Anne M.; Isaacs, Claudine; Boughey, Judy C.; Han, Hyo S.; Buxton, Meredith; Clennell, Julia L.; Asare, Smita M.; Steeg, Katherine; Wilson, Amy; Singhrao, Ruby; Matthews, Jeffrey B.; Perlmutter, Jane; Fraser Symmans, W.; Hylton, Nola M.; Demichele, Angela M.; Yee, Douglas; Van't Veer, Laura J.; Berry, Donald A.; Esserman, Laura J. 分享 收藏
Multi-platform biomarkers of response to an immune checkpoint inhibitor in the neoadjuvant I-SPY 2 trial for early-stage breast cancer Campbell, Michael J.; Wolf, Denise M.; Yau, Christina; Brown-Swigart, Lamorna; Wulfkuhle, Julie; Gallagher, Isela R.; Zhu, Zelos; Bolen, Jennifer; Vandenberg, Scott; Hoyt, Clifford; Mori, Hidetoshi; Borowsky, Alexander; Sit, Laura; Perlmutter, Jane; Asare, Smita M.; Nanda, Rita; Liu, Minetta C.; Yee, Douglas; Demichele, Angela M.; Hylton, Nola M.; Pusztai, Lajos; Berry, Donald A.; Hirst, Gillian L.; Petricoin, Emanuel F.; van't Veer, Laura; Esserman, Laura 分享 收藏
Datopotamab-deruxtecan in early-stage breast cancer: the sequential multiple assignment randomized I-SPY2.2 phase 2 trial Datopotamab-deruxtecan治疗早期乳腺癌: 序贯多重分配随机I-SPY2.2 2期试验 Khoury, Katia; Meisel, Jane L.; Yau, Christina; Rugo, Hope S.; Nanda, Rita; Davidian, Marie; Tsiatis, Butch; Chien, A. Jo; Wallace, Anne M.; Arora, Mili; Rozenblit, Mariya; Hershman, Dawn L.; Zimmer, Alexandra; Clark, Amy S.; Beckwith, Heather; Elias, Anthony D.; Stringer-Reasor, Erica; Boughey, Judy C.; Nangia, Chaitali; Vaklavas, Christos; Omene, Coral; Albain, Kathy S.; Kalinsky, Kevin M.; Isaacs, Claudine; Tseng, Jennifer; Torres, Evanthia T. Roussos; Thomas, Brittani; Thomas, Alexandra; Sanford, Amy; Balassanian, Ronald; Ewing, Cheryl; Yeung, Kay; Sauder, Candice; Sanft, Tara; Pusztai, Lajos; Trivedi, Meghna S.; Outhaythip, Ashton; Li, Wen; Onishi, Natsuko; Asare, Adam L.; Beineke, Philip; Norwood, Peter; Brown-Swigart, Lamorna; Hirst, Gillian L.; Matthews, Jeffrey B.; Moore, Brian; Symmans, W. Fraser; Price, Elissa; Beedle, Carolyn; Perlmutter, Jane; Pohlmann, Paula; Shatsky, Rebecca A.; Demichele, Angela; Yee, Douglas; van't Veer, Laura J.; Hylton, Nola M.; Esserman, Laura J. 分享 收藏
Datopotamab-deruxtecan plus durvalumab in early-stage breast cancer: the sequential multiple assignment randomized I-SPY2.2 phase 2 trial Datopotamab-deruxtecan联合durvalumab治疗早期乳腺癌: 序贯多重分配随机I-SPY2.2 2期试验 Shatsky, Rebecca A.; Trivedi, Meghna S.; Yau, Christina; Nanda, Rita; Rugo, Hope S.; Davidian, Marie; Tsiatis, Butch; Wallace, Anne M.; Chien, A. Jo; Stringer-Reasor, Erica; Boughey, Judy C.; Omene, Coral; Rozenblit, Mariya; Kalinsky, Kevin; Elias, Anthony D.; Vaklavas, Christos; Beckwith, Heather; Williams, Nicole; Arora, Mili; Nangia, Chaitali; Torres, Evanthia T. Roussos; Thomas, Brittani; Albain, Kathy S.; Clark, Amy S.; Falkson, Carla; Hershman, Dawn L.; Isaacs, Claudine; Thomas, Alexandra; Tseng, Jennifer; Sanford, Amy; Yeung, Kay; Boles, Sarah; Chen, Yunni Yi; Huppert, Laura; Jahan, Nusrat; Parker, Catherine; Giridhar, Karthik; Howard, Frederick M.; Blackwood, M. Michele; Sanft, Tara; Li, Wen; Onishi, Natsuko; Asare, Adam L.; Beineke, Philip; Norwood, Peter; Brown-Swigart, Lamorna; Hirst, Gillian L.; Matthews, Jeffrey B.; Moore, Brian; Symmans, W. Fraser; Price, Elissa; Heditsian, Diane; Lestage, Barbara; Perlmutter, Jane; Pohlmann, Paula; Demichele, Angela; Yee, Douglas; van 't Veer, Laura J.; Hylton, Nola M.; Esserman, Laura J. 分享 收藏
Magnetic resonance imaging insights from active surveillance of women with ductal carcinoma in situ Greenwood, Heather I.; Rodas, Cristian K. Maldonado; Freimanis, Rita I.; Glencer, Alexa C.; Miller, Phoebe N.; Mukhtar, Rita A.; Brabham, Case; Yau, Christina; Rosenbluth, Jennifer M.; Hirst, Gillian L.; Campbell, Michael J.; Borowsky, Alexander; Hylton, Nola; Esserman, Laura J.; Basu, Amrita 分享 收藏
18F-FDG Dedicated Breast PET Complementary to Breast MRI for Evaluating Early Response to Neoadjuvant Chemotherapy 18F-FDG专用乳腺PET辅助乳腺MRI评估新辅助化疗的早期反应 Diwanji, Devan; Onishi, Natsuko; Hathi, Deep K.; Lawhn-Heath, Courtney; Kornak, John; Li, Wen; Guo, Ruby; Molina-Vega, Julissa; Seo, Youngho; Flavell, Robert R.; Heditsian, Diane; Brain, Susie; Esserman, Laura J.; Joe, Bonnie N.; Hylton, Nola M.; Jones, Ella F.; Ray, Kimberly M. 分享 收藏
Cell-free DNA concentration as a biomarker of response and recurrence in HER-2 negative breast cancer receiving neoadjuvant chemotherapy Magbanua, Mark Jesus M.; Ahmed, Ziad; Sayaman, Rosalyn W.; Brown-Swigart, Lamorna; Hirst, Gillian L.; Yau, Christina; Wolf, Denise M.; Li, Wen; Delson, Amy L.; Perlmutter, Jane; Symmans, W. Fraser; Yee, Douglas; Hylton, Nola M.; Esserman, Laura J.; DeMichele, Angela M.; Rugo, Hope S.; van't Veer, Laura J. 分享 收藏
Intratumoral injection of mRNA-2752 and anti-PD-1 results in rapid regression of HER2 positive and or Hormone Receptor Negative DCIS: Phase 1 study results Esserman, Laura J.; Ramalingam, Kirithiga; Woody, Rachel; Glencer, Alexa; Schwartz, Christopher; Mori, Hidetoshi; Wong, Jasmine; Hirst, Gillian; Rosenbluth, Jennifer; Hylton, Nola; Onishi, Natsuko; Borowsky, Alexander D.; Campbell, Michael J. 分享 收藏
Breast Multiparametric MRI for Prediction of Neoadjuvant Chemotherapy Response in Breast Cancer: The BMMR2 Challenge 乳腺多参数MRI预测乳腺癌新辅助化疗反应: BMMR2挑战 Li, Wen; Partridge, Savannah C.; Newitt, David C.; Steingrimsson, Jon; Marques, Helga S.; Bolan, Patrick J.; Hirano, Michael; Bearce, Benjamin Aaron; Kalpathy-Cramer, Jayashree; Boss, Michael A.; Teng, Xinzhi; Zhang, Jiang; Cai, Jing; Kontos, Despina; Cohen, Eric A.; Mankowski, Walter C.; Liu, Michael; Ha, Richard; Pellicer-Valero, Oscar J.; Maier-Hein, Klaus; Rabinovici-Cohen, Simona; Tlusty, Tal; Ozery-Flato, Michal; Parekh, Vishwa S.; Jacobs, Michael A.; Yan, Ran; Sung, Kyunghyun; Kazerouni, Anum S.; Dicarlo, Julie C.; Yankeelov, Thomas E.; Chenevert, Thomas L.; Hylton, Nola M. 分享 收藏
Protein signaling and drug target activation signatures to guide therapy prioritization: Therapeutic resistance and sensitivity in the I-SPY 2 Trial 蛋白质信号和药物靶标激活特征以指导治疗优先顺序: i-spy 2试验中的治疗抗性和敏感性 Gallagher, Rosa I.; Wulfkuhle, Julia; Wolf, Denise M.; Brown-Swigart, Lamorna; Yau, Christina; O'Grady, Nicholas; Basu, Amrita; Lu, Ruixiao; Campbell, Michael J.; Magbanua, Mark J.; Coppe, Jean-Philippe; Asare, Smita M.; Sit, Laura; Matthews, Jeffrey B.; Perlmutter, Jane; Hylton, Nola; Liu, Minetta C.; Symmans, W. Fraser; Rugo, Hope S.; Isaacs, Claudine; Demichele, Angela M.; Yee, Douglas; Pohlmann, Paula R.; Hirst, Gillian L.; Esserman, Laura J.; van 't Veer, Laura J.; Petricoin, Emanuel F. 分享 收藏
Reduction of anthracycline use with a combined imaging and pathology prediction model in the neoadjuvant I-SPY2 trial DeMichele, A.; Price, E.; Venters, S.; Li, W.; Wolf, D.; Gibbs, J.; Brown-Swigart, L.; Klein, M.; Onishi, N.; Yau, C.; Yee, D.; Isaacs, C.; Perlmutter, J.; Rugo, H. S.; Van't Veer, L. J.; Boughey, J.; Symmans, F.; Hylton, N.; Esserman, L. 分享 收藏
Effect of Longitudinal Variation in Tumor Volume Estimation for MRI-guided Personalization of Breast Cancer Neoadjuvant Treatment Onishi, Natsuko; Bareng, Teffany Joy; Gibbs, Jessica; Li, Wen; Price, Elissa R.; Joe, Bonnie N.; Kornak, John; Esserman, Laura J.; Newitt, David C.; Hylton, Nola M. 分享 收藏
Computational drug repositioning for the identification of new agents to sensitize drug-resistant breast tumors across treatments and receptor subtypes Yu, Katharine; Basu, Amrita; Yau, Christina; Wolf, Denise M.; Goodarzi, Hani; Bandyopadhyay, Sourav; Korkola, James E.; Hirst, Gillian L.; Asare, Smita; DeMichele, Angela; Hylton, Nola; Yee, Douglas; Esserman, Laura; van 't Veer, Laura; Sirota, Marina 分享 收藏
Comparison of Mammography AI Algorithms with a Clinical Risk Model for 5-year Breast Cancer Risk Prediction: An Observational Study 乳腺摄影AI算法与5年乳腺癌风险预测的临床风险模型的比较: 一项观察性研究 Arasu, Vignesh A.; Habel, Laurel A.; Achacoso, Ninah S.; Buist, Diana S. M.; Cord, Jason B.; Esserman, Laura J.; Hylton, Nola M.; Glymour, M. Maria; Kornak, John; Kushi, Lawrence H.; Lewis, Donald A.; Liu, Vincent X.; Lydon, Caitlin M.; Miglioretti, Diana L.; Navarro, Daniel A.; Pu, Albert; Shen, Li; Sieh, Weiva; Yoon, Hyo-Chun; Lee, Catherine 分享 收藏
Radiomic tumor phenotypes augment molecular profiling in predicting recurrence free survival after breast neoadjuvant chemotherapy Chitalia, Rhea; Miliotis, Marios; Jahani, Nariman; Tastsoglou, Spyros; McDonald, Elizabeth S.; Belenky, Vivian; Cohen, Eric A.; Newitt, David; van't Veer, Laura J.; Esserman, Laura; Hylton, Nola; DeMichele, Angela; Hatzigeorgiou, Artemis; Kontos, Despina 分享 收藏
Evaluation of anti-PD-1 Cemiplimab plus anti-LAG-3 REGN3767 in early-stage, high-risk HER2-negative breast cancer: Results from the neoadjuvant I-SPY 2 TRIAL Isaacs, Claudine; Nanda, Rita; Chien, Jo; Trivedi, Meghna S.; Stringer-Reasor, Erica; Vaklavas, Christos; Boughey, Judy C.; Sanford, Amy; Wallace, Anne; Clark, Amy S.; Thomas, Alexandra; Albain, Kathy S.; Kennedy, Laura C.; Sanft, Tara B.; Kalinsky, Kevin; Han, Hyo S.; Williams, Nicole; Arora, Mili; Elias, Anthony; Falkson, Carla; Asare, Smita; Lu, Ruixiao; Pitsouni, Maria; Wilson, Amy; Perlmutter, Jane; Rugo, Hope; Schwab, Richard; Symmans, W. Fraser; Hylton, Nola M.; Van't Veer, Laura; Yee, Douglas; DeMichele, Angela; Berry, Donald; Esserman, Laura J. 分享 收藏
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