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C

Christina Therkildsen

Hvidovre Hospital
H指数:23
被引数:2,542

个人简介

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教育背景

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工作经历

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荣誉奖项

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Cross-dataset pan-cancer detection by correlating cell-free DNA fragment coverage with open chromatin sites across cell types

通过关联细胞自由DNA片段覆盖度与跨细胞类型的开放染色质位点，进行跨数据集泛癌检测

Nature Communications
IF15.7
2025-11-210
OAAI
Ludvig Renbo Olsen; Denis Odinokov; Jakob Qvortrup Holsting; Karoline Kondrup; Laura Iisager; Maria Rusan; Simon Buus; Britt Elmedal Laursen; Michael Borre; Mads Ryø Jochumsen; Kirsten Bouchelouche; Amanda Frydendahl; Mads Heilskov Rasmussen; Tenna Vesterman Henriksen; Marijana Nesic; Christina Demuth; Sia Viborg Lindskrog; Iver Nordentoft; Philippe Lamy; Christina Therkildsen; Lars Dyrskjøt; Karina Dalsgaard Sørensen; Claus Lindbjerg Andersen; Anders Jakobsen Skanderup; Søren Besenbacher
Mesalamine for Colorectal Cancer Prevention Programme in Lynch syndrome (MesaCAPP): a multicentre, multinational, randomised, two-arm, double-blind, phase II clinical study with mesalamine or placebo in carriers with Lynch syndrome - a study protocol

美沙拉嗪用于林奇综合征结直肠癌预防计划（MesaCAPP）：一项多中心、跨国、随机、双臂、双盲、II期临床研究，研究美沙拉嗪或安慰剂在林奇综合征携带者中的效果——研究方案

BMJ OPEN
IF2.3
2025-11-090
OA
Backman, Ann-Sofie; Frank, Alexander; Lindberg, Lars Joachim; Ljungman, David; Silander, Gustav; Gustafsson, Rita J.; Bozso, Tunde; Schmidt, Peter T.; Ingre, Michael; Mittlbock, Martina; Lowbeer, Christian; Marsal, Jan; Lindblom, Annika; Tham, Emma; Therkildsen, Christina; Gasche, Christoph
Circulating Tumor DNA in Addition to Fecal Immunochemical Test in a Dual-Test Colorectal Cancer Screening Approach

在双重检测的结直肠癌筛查方法中，循环肿瘤DNA与粪便免疫化学检测联合应用

Clinical Colorectal Cancer
IF3.2
2025-03-190
OAAI
Caroline L. Kahn; Mathias M. Petersen; Jakob Kleif; Mees S.E. Mansvelders; Morten Rasmussen; Lars N. Jørgensen; Jesper Vilandt; Jakob B. Seidelin; Claudia Jaensch; Peter Bondeven; Kåre A. Gotschalck; Uffe S. Løve; Berit Andersen; Ib J. Christensen; Lawrence C. LaPoint; Christina Therkildsen
Whole-genome sequencing of cell-free DNA reveals DNA of tumor origin in plasma from patients with colorectal adenomas

无细胞DNA的全基因组测序揭示了结直肠腺瘤患者血浆中肿瘤来源的DNA

MOLECULAR ONCOLOGY
IF4.5
2025-01-200
OA
Frydendahl, Amanda; Widman, Adam J.; Ogaard, Nadia; Arora, Anushri; Halmos, Daniel; Nors, Jesper; Ahrenfeldt, Johanne; Henriksen, Tenna V.; Demuth, Christina; Raaby, Line; Rasmussen, Mads H.; Therkildsen, Christina; Landau, Dan A.; Andersen, Claus L.
Development of an algorithm combining blood-based biomarkers, fecal immunochemical test, and age for population-based colorectal cancer screening
GASTROINTESTINAL ENDOSCOPY
IF7.5
2024-12-012
OAAI
Petersen, Mathias M.; Kleif, Jakob; Liggett, Jason; Rasmussen, Morten; Jorgensen, Lars N.; Vilandt, Jesper; Seidelin, Jakob B.; Beertsen, Carla M. T.; Heijboer, Annemieke C.; Jaensch, Claudia; Bondeven, Peter; Gotschalck, Kare A.; Love, Uffe S.; Gawel, Susan H.; Andersen, Berit; Christensen, Ib J.; Mayer, Eric; Davis, Gerard J.; Therkildsen, Christina
Circulating tumour DNA and risk of recurrence in patients with asymptomatic versus symptomatic colorectal cancer
BRITISH JOURNAL OF CANCER
IF6.8
2024-10-100
OA
Ogaard, Nadia; Jensen, Sarah Ostrup; Orntoft, Mai-Britt Worm; Demuth, Christina; Rasmussen, Mads Heilskov; Henriksen, Tenna Vesterman; Nors, Jesper; Frydendahl, Amanda; Lyskjaer, Iben; Nesic, Marijana; Therkildsen, Christina; Kleif, Jakob; Gogenur, Mikail; Jorgensen, Lars Nannestad; Vilandt, Jesper; Seidelin, Jakob Benedict; Gotschalck, Kare Anderson; Jaensch, Claudia; Andersen, Berit; Love, Uffe Schou; Thorlacius-Ussing, Ole; Andersen, Per Vadgaard; Kolbro, Thomas; Monti, Alessio; Kildsig, Jeppe; Bondeven, Peter; Schlesinger, Nis Hallundbaek; Iversen, Lene Hjerrild; Rasmussen, Morten; Gogenur, Ismail; Bramsen, Jesper Bertram; Andersen, Claus Lindbjerg
Ultrasensitive plasma-based monitoring of tumor burden using machine-learning-guided signal enrichment

使用机器学习引导的信号富集技术对基于血浆的肿瘤负荷进行超灵敏监测

NATURE MEDICINE
IF50
2024-06-144
OAAI
Widman, Adam J.; Shah, Minita; Frydendahl, Amanda; Halmos, Daniel; Khamnei, Cole C.; Ogaard, Nadia; Rajagopalan, Srinivas; Arora, Anushri; Deshpande, Aditya; Hooper, William F.; Quentin, Jean; Bass, Jake; Zhang, Mingxuan; Langanay, Theophile; Andersen, Laura; Steinsnyder, Zoe; Liao, Will; Rasmussen, Mads Heilskov; Henriksen, Tenna Vesterman; Jensen, Sarah ostrup; Nors, Jesper; Therkildsen, Christina; Sotelo, Jesus; Brand, Ryan; Schiffman, Joshua S.; Shah, Ronak H.; Cheng, Alexandre Pellan; Maher, Colleen; Spain, Lavinia; Krause, Kate; Frederick, Dennie T.; den Brok, Wendie; Lohrisch, Caroline; Shenkier, Tamara; Simmons, Christine; Villa, Diego; Mungall, Andrew J.; Moore, Richard; Zaikova, Elena; Cerda, Viviana; Kong, Esther; Lai, Daniel; Malbari, Murtaza S.; Marton, Melissa; Manaa, Dina; Winterkorn, Lara; Gelmon, Karen; Callahan, Margaret K.; Boland, Genevieve; Potenski, Catherine; Wolchok, Jedd D.; Saxena, Ashish; Turajlic, Samra; Imielinski, Marcin; Berger, Michael F.; Aparicio, Sam; Altorki, Nasser K.; Postow, Michael A.; Robine, Nicolas; Andersen, Claus Lindbjerg; Landau, Dan A.
Optimizing Screening for Colorectal Cancer: An Algorithm Combining Fecal Immunochemical Test, Blood-Based Cancer-Associated Proteins and Demographics to Reduce Colonoscopy Burden
CLINICAL COLORECTAL CANCER
IF3.2
2023-06-016
OAAI
Petersen, Mathias M.; Kleif, Jakob; Jorgensen, Lars N.; Hendel, Jakob W.; Seidelin, Jakob B.; Madsen, Mogens R.; Vilandt, Jesper; Brandsborg, Soren; Rasmussen, Jorn S.; Andersen, Lars M.; Khalid, Ali; Ferm, Linnea; Gawel, Susan H.; Martens, Frans; Andersen, Berit; Rasmussen, Morten; Davis, Gerard J.; Christensen, Ib J.; Therkildsen, Christina
Mortality by age, gene and gender in carriers of pathogenic mismatch repair gene variants receiving surveillance for early cancer diagnosis and treatment: a report from the prospective Lynch syndrome database

接受早期癌症诊断和治疗监测的致病性错配修复基因变异携带者的年龄，基因和性别死亡率: 前瞻性Lynch综合征数据库的报告

ECLINICALMEDICINE
IF10
2023-04-0130
OAAI
Dominguez-Valentin, Mev; Haupt, Saskia; Seppala, Toni T.; Sampson, Julian R.; Sunde, Lone; Bernstein, Inge; Jenkins, Mark A.; Engel, Christoph; Aretz, Stefan; Nielsen, Maartje; Capella, Gabriel; Balaguer, Francesc; Evans, Dafydd Gareth; Burn, John; Holinski-Feder, Elke; Bertario, Lucio; Bonanni, Bernardo; Lindblom, Annika; Levi, Zohar; Macrae, Finlay; Winship, Ingrid; Plazzer, John-Paul; Sijmons, Rolf; Laghi, Luigi; Della Valle, Adriana; Heinimann, Karl; Debniak, Tadeusz; Fruscio, Robert; Lopez-Koestner, Francisco; Alvarez-Valenzuela, Karin; Katz, Lor H.; Laish, Ido; Vainer, Elez; Vaccaro, Carlos; Carraro, Dirce Maria; Monahan, Kevin; Half, Elizabeth; Stakelum, Aine; Winter, Des; Kennelly, Rory; Gluck, Nathan; Sheth, Harsh; Abu-Freha, Naim; Greenblatt, Marc; Rossi, Benedito Mauro; Bohorquez, Mabel; Cavestro, Giulia Martina; Lino-Silva, Leonardo S.; Horisberger, Karoline; Tibiletti, Maria Grazia; do Nascimento, Ivana; Thomas, Huw; Rossi, Norma Teresa; da Silva, Leandro Apolinario; Zarand, Attila; Ruiz-Banobre, Juan; Heuveline, Vincent; Mecklin, Jukka-Pekka; Pylvaenaeinen, Kirsi; Renkonen-Sinisalo, Laura; Lepistoe, Anna; Peltomaeki, Paeivi; Therkildsen, Christina; Madsen, Mia Gebauer; Burgdorf, Stefan Kobbelgaard; Hopper, John L.; Win, Aung Ko; Haile, Robert W.; Lindor, Noralane; Gallinger, Steven; Le Marchand, Loic; Newcomb, Polly A.; Figueiredo, Jane; Buchanan, Daniel D.; Thibodeau, Stephen N.; Doeberitz, Magnus von Knebel; Loeffler, Markus; Rahner, Nils; Schroeck, Evelin; Steinke-Lange, Verena; Schmiegel, Wolff; Vangala, Deepak; Perne, Claudia; Hueneburg, Robert; Redler, Silke; Buettner, Reinhard; Weitz, Jurgen; Pineda, Marta; Duenas, Nuria; Vidal, Joan Brunet; Moreira, Leticia; Sanchez, Ariadna; Hovig, Eivind; Nakken, Sigve; Green, Kate; Lalloo, Fiona; Hill, James; Crosbie, Emma; Mints, Miriam; Goldberg, Yael; Tjandra, Douglas; ten Broeke, Sanne W.; Kariv, Revital; Rosner, Guy; Advani, Suresh H.; Thomas, Lidiya; Shah, Pankaj; Shah, Mithun; Neffa, Florencia; Esperon, Patricia; Pavicic, Walter; Torrezan, Giovana Tardin; Bassaneze, Thiago; Martin, Claudia Alejandra; Moslein, Gabriela; Moller, Pal
No Difference in Penetrance between Truncating and Missense/Aberrant Splicing Pathogenic Variants in MLH1 and MSH2: A Prospective Lynch Syndrome Database Study
JOURNAL OF CLINICAL MEDICINE
IF2.9
2021-06-2813
OAAI
Dominguez-Valentin, Mev; Plazzer, John-Paul; Sampson, Julian R.; Engel, Christoph; Aretz, Stefan; Jenkins, Mark A.; Sunde, Lone; Bernstein, Inge; Capella, Gabriel; Balaguer, Francesc; Macrae, Finlay; Winship, Ingrid M.; Thomas, Huw; Evans, Dafydd Gareth; Burn, John; Greenblatt, Marc; Cappel, Wouter H. de Vos Tot Nederveen; Sijmons, Rolf H.; Nielsen, Maartje; Bertario, Lucio; Bonanni, Bernardo; Tibiletti, Maria Grazia; Cavestro, Giulia Martina; Lindblom, Annika; Della Valle, Adriana; Lopez-Kostner, Francisco; Alvarez, Karin; Gluck, Nathan; Katz, Lior; Heinimann, Karl; Vaccaro, Carlos A.; Nakken, Sigve; Hovig, Eivind; Green, Kate; Lalloo, Fiona; Hill, James; Vasen, Hans F. A.; Perne, Claudia; Buettner, Reinhard; Goergens, Heike; Holinski-Feder, Elke; Morak, Monika; Holzapfel, Stefanie; Hueneburg, Robert; Doeberitz, Magnus von Knebel; Loeffler, Markus; Rahner, Nils; Weitz, Juergen; Steinke-Lange, Verena; Schmiegel, Wolff; Vangala, Deepak; Crosbie, Emma J.; Pineda, Marta; Navarro, Matilde; Brunet, Joan; Moreira, Leticia; Sanchez, Ariadna; Serra-Burriel, Miquel; Mints, Miriam; Kariv, Revital; Rosner, Guy; Pinero, Tamara Alejandra; Pavicic, Walter Hernan; Kalfayan, Pablo; ten Broeke, Sanne W.; Mecklin, Jukka-Pekka; Pylvanainen, Kirsi; Renkonen-Sinisalo, Laura; Lepisto, Anna; Peltomaki, Paivi; Hopper, John L.; Win, Aung Ko; Buchanan, Daniel D.; Lindor, Noralane M.; Gallinger, Steven; Le Marchand, Loic; Newcomb, Polly A.; Figueiredo, Jane C.; Thibodeau, Stephen N.; Therkildsen, Christina; Hansen, Thomas V. O.; Lindberg, Lars; Rodland, Einar Andreas; Neffa, Florencia; Esperon, Patricia; Tjandra, Douglas; Moslein, Gabriela; Seppala, Toni T.; Moller, Pal
Uptake of hysterectomy and bilateral salpingooophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report
EUROPEAN JOURNAL OF CANCER
IF7.1
2021-05-0114
OAAI
Seppala, Toni T.; Dominguez-Valentin, Mev; Crosbie, Emma J.; Engel, Christoph; Aretz, Stefan; Macrae, Finlay; Winship, Ingrid; Capella, Gabriel; Thomas, Huw; Hovig, Eivind; Nielsen, Maartje; Sijmons, Rolf H.; Bertario, Lucio; Bonanni, Bernardo; Tibiletti, Maria G.; Cavestro, Giulia M.; Mints, Miriam; Gluck, Nathan; Katz, Lior; Heinimann, Karl; Vaccaro, Carlos A.; Green, Kate; Lalloo, Fiona; Hill, James; Schmiegel, Wolff; Vangala, Deepak; Perne, Claudia; Strauss, Hans-Georg; Tecklenburg, Johanna; Holinski-Feder, Elke; Steinke-Lange, Verena; Mecklin, Jukka-Pekka; Plazzer, John-Paul; Pineda, Marta; Navarro, Matilde; Vida, Joan B.; Kariv, Revital; Rosner, Guy; Pinero, Tamara A.; Pavicic, Walter; Kalfayan, Pablo; Ten Broeke, Sanne W.; Jenkins, Mark A.; Sunde, Lone; Bernstein, Inge; Burn, John; Greenblatt, Marc; Cappel, Wouter H. de Vos Tot Nederveen; Della Valle, Adriana; Lopez-Koestner, Francisco; Alvarez, Karin; Buettner, Reinhard; Goergens, Heike; Morak, Monika; Holzapfel, Stefanie; Hueneburg, Robert; Doeberitz, Magnus von Knebel; Loeffler, Markus; Redler, Silke; Weitz, Jurgen; Pylvaenaeinen, Kirsi; Renkonen-Sinisalo, Laura; Lepisto, Anna; Hopper, John L.; Win, Aung K.; Lindor, Noralane M.; Gallinger, Steven; Marchand, Loic Le; Newcomb, Polly A.; Figueiredo, Jane C.; Thibodeau, Stephen N.; Therkildsen, Christina; Wadt, Karin A. W.; Mourits, Marian J. E.; Ketabi, Zohreh; Denton, Oliver G.; Rodland, Einar A.; Vasen, Hans; Neffa, Florencia; Esperon, Patricia; Tjandra, Douglas; Moeslein, Gabriela; Rokkones, Erik; Sampson, Julian R.; Evans, D. G.; Moller, Pal
Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report
GENETICS IN MEDICINE
IF6.2
2021-04-0125
OAAI
Dominguez-Valentin, Mev; Crosbie, Emma J.; Engel, Christoph; Aretz, Stefan; Macrae, Finlay; Winship, Ingrid; Capella, Gabriel; Thomas, Huw; Nakken, Sigve; Hovig, Eivind; Nielsen, Maartje; Sijmons, Rolf H.; Bertario, Lucio; Bonanni, Bernardo; Tibiletti, Maria Grazia; Cavestro, Giulia Martina; Mints, Miriam; Gluck, Nathan; Katz, Lior; Heinimann, Karl; Vaccaro, Carlos A.; Green, Kate; Lalloo, Fiona; Hill, James; Schmiegel, Wolff; Vangala, Deepak; Perne, Claudia; Strauss, Hans-Georg; Tecklenburg, Johanna; Holinski-Feder, Elke; Steinke-Lange, Verena; Mecklin, Jukka-Pekka; Plazzer, John-Paul; Pineda, Marta; Navarro, Matilde; Brunet Vidal, Joan; Kariv, Revital; Rosner, Guy; Alejandra Pinero, Tamara; Laura Gonzalez, Maria; Kalfayan, Pablo; Ryan, Neil; Ten Broeke, Sanne W.; Jenkins, Mark A.; Sunde, Lone; Bernstein, Inge; Burn, John; Greenblatt, Marc; Cappel, Wouter H. de Vos tot Nederveen; Della Valle, Adriana; Lopez-Koestner, Francisco; Alvarez, Karin; Buettner, Reinhard; Goergens, Heike; Morak, Monika; Holzapfel, Stefanie; Hueneburg, Robert; Doeberitz, Magnus von Knebel; Loeffler, Markus; Rahner, Nils; Weitz, Jurgen; Pylvanainen, Kirsi; Renkonen-Sinisalo, Laura; Lepisto, Anna; Auranen, Annika; Hopper, John L.; Win, Aung Ko; Haile, Robert W.; Lindor, Noralane M.; Gallinger, Steven; Le Marchand, Loic; Newcomb, Polly A.; Figueiredo, Jane C.; Thibodeau, Stephen N.; Therkildsen, Christina; Okkels, Henrik; Ketabi, Zohreh; Denton, Oliver G.; Rodland, Einar Andreas; Vasen, Hans; Neffa, Florencia; Esperon, Patricia; Tjandra, Douglas; Moeslein, Gabriela; Sampson, Julian R.; Evans, D. Gareth; Seppala, Toni T.; Moller, Pal

研究方向

暂未获取到该数据
M
Mef Nilbert
H 指数:55论文数:325被引数:1.4万
M
Mev Dominguez–Valentin
H 指数:27论文数:117被引数:3,539
I
Inge Bernstein
H 指数:48论文数:207被引数:1.1万
J
Jakob Kleif
H 指数:16论文数:71被引数:1,195
D
D. Gareth Evans
H 指数:182论文数:2,473被引数:13.4万
K
Karl Heinimann
H 指数:46论文数:182被引数:8,961
J
John Burn
H 指数:99论文数:622被引数:4.0万
I
Ingrid Winship
H 指数:60论文数:495被引数:1.7万
G
Gabriel Capellá
H 指数:82论文数:694被引数:2.7万
M
Maartje Nielsen
H 指数:43论文数:207被引数:6,826