未登录 Preclinical development of anti-CD21 chimeric antigen receptor T cells to treat T cell acute lymphoblastic leukemia 抗CD21嵌合抗原受体T细胞治疗T细胞急性淋巴细胞白血病的临床前开发 Maciocia, Nicola; Hoekx, Malika; Acuna, Ciaran; Wade, Brandon; Burley, Amy; Ramanayake, Saumya; Nannini, Francesco; Wawrzyniecka, Patrycja A.; Karpanasamy, Thaneswari; Schuldt, Maria; Ng, Stephanie; Ferrari, Mathieu; Marafioti, Teresa; Gritti, Giuseppe; Onuoha, Shimobi; O'Connor, David; Lee, Lydia; Mansour, Marc; Khwaja, Asim; Pule, Martin; Maciocia, Paul 分享 收藏
Obecabtagene Autoleucel in Adults with B-Cell Acute Lymphoblastic Leukemia 成人b细胞急性淋巴细胞白血病的Obecabtagene自体白血病 Roddie, Claire; Sandhu, Karamjeet S.; Tholouli, Eleni; Logan, Aaron C.; Shaughnessy, Paul; Barba, Pere; Ghobadi, Armin; Guerreiro, Manuel; Yallop, Deborah; Abedi, Mehrdad; Pantin, Jeremy M.; Yared, Jean A.; Beitinjaneh, Amer M.; Chaganti, Sridhar; Hodby, Katharine; Menne, Tobias; Arellano, Martha L.; Malladi, Ram; Shah, Bijal D.; Mountjoy, Luke; O'Dwyer, Kristen M.; Peggs, Karl S.; Lao-Sirieix, Pierre; Zhang, Yiyun; Brugger, Wolfram; Braendle, Edgar; Pule, Martin; Bishop, Michael R.; Deangelo, Daniel J.; Park, Jae H.; Jabbour, Elias 分享 收藏
In Situ Tracking of TCRβ Isoforms for Detection of T Cell Clonality: Implication for Precision Diagnosis and Targeted Immunotherapy of T-Cell Neoplasms Manipadam, Marie Therese; Marra, Andrea; Ramsay, Alan; Padmasri, Sugerdana; Gosh, Adheesh; Neves, Margarida; Bailey, Chris; Pomplun, Sabine; Maciocia, Paul; Cwynarski, Kate; Ferrari, Mathieu; Lao-Siriex, Pierre; Piris, Miguel; Falini, Brunangelo; Linch, David; Rosenwald, Andreas; Pule, Martin; Zamo, Alberto; Marafioti, Teresa 分享 收藏
TRBC1-CAR T cell therapy in peripheral T cell lymphoma: a phase 1/2 trial Cwynarski, Kate; Iacoboni, Gloria; Tholouli, Eleni; Menne, Tobias; Irvine, David A.; Balasubramaniam, Nivetha; Wood, Leigh; Shang, Justin; Xue, Eric; Zhang, Yiyun; Basilico, Silvia; Neves, Margarida; Raymond, Meera; Scott, Ian; El-Kholy, Mohamed; Jha, Ram; Dainton-Smith, Heather; Hussain, Rehan; Day, William; Ferrari, Mathieu; Thomas, Simon; Lilova, Koki; Brugger, Wolfram; Marafioti, Teresa; Lao-Sirieix, Pierre; Maciocia, Paul; Pule, Martin 分享 收藏
Risk Factors Associated with Sub-Optimal Outcomes Following Obecabtagene autoleucel (obe-cel) for Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia (R/R B-ALL): What We Have Learned from the FELIX Trial 与使用Obecabtagene autoleucel（obe-cel）治疗复发/难治性B细胞急性淋巴细胞白血病（R/R B-ALL）后效果不佳相关的风险因素：我们从FELIX试验中学到的经验 Roddie, Claire; Park, Jae H.; Shaughnessy, Paul; Logan, Aaron C.; Sandhu, Karamjeet S.; Abedi, Mehrdad; Shah, Bijal; Bishop, Michael R.; Deangelo, Daniel J.; Brugger, Wolfram; Pule, Martin A.; Shang, Justin; Jabbour, Elias 分享 收藏
Transcriptional signatures associated with persisting CD19 CAR-T cells in children with leukemia Anderson, Nathaniel D.; Birch, Jack; Accogli, Theo; Criado, Ignacio; Khabirova, Eleonora; Parks, Conor; Wood, Yvette; Young, Matthew D.; Porter, Tarryn; Richardson, Rachel; Albon, Sarah J.; Popova, Bilyana; Lopes, Andre; Wynn, Robert; Hough, Rachael; Gohil, Satyen H.; Pule, Martin; Amrolia, Persis J.; Behjati, Sam; Ghorashian, Sara 分享 收藏
Dual T-cell constant β chain (TRBC)1 and TRBC2 staining for the identification of T-cell neoplasms by flow cytometry 双T细胞常数 β 链 (TRBC)1和TRBC2染色通过流式细胞术鉴定T细胞肿瘤 Horna, Pedro; Weybright, Matthew J.; Ferrari, Mathieu; Jungherz, Dennis; Peng, Yayi; Akbar, Zulaikha; Tudor Ilca, F.; Otteson, Gregory E.; Seheult, Jansen N.; Ortmann, Janosch; Shi, Min; Maciocia, Paul M.; Herling, Marco; Pule, Martin A.; Olteanu, Horatiu 分享 收藏
Structure-guided engineering of immunotherapies targeting TRBC1 and TRBC2 in T cell malignancies T细胞恶性肿瘤中靶向TRBC1和TRBC2的免疫疗法的结构指导工程 Ferrari, Mathieu; Righi, Matteo; Baldan, Vania; Wawrzyniecka, Patrycja; Bulek, Anna; Kinna, Alexander; Ma, Biao; Bughda, Reyisa; Akbar, Zulaikha; Srivastava, Saket; Gannon, Isaac; Robson, Mathew; Sillibourne, James; Jha, Ram; El-Kholy, Mohamed; Amin, Oliver Muhammad; Kokalaki, Evangelia; Banani, Mohammed Amin; Hussain, Rehan; Day, William; Lim, Wen Chean; Ghongane, Priyanka; Hopkins, Jade R.; Jungherz, Dennis; Herling, Marco; Welin, Martin; Surade, Sachin; Dyson, Michael; Mccafferty, John; Logan, Derek; Cordoba, Shaun; Thomas, Simon; Sewell, Andrew; Maciocia, Paul; Onuoha, Shimobi; Pule, Martin 分享 收藏
Dual targeting of CD19 and CD22 against B-ALL using a novel high-sensitivity aCD22 CAR Kokalaki, Evangelia; Ma, Biao; Ferrari, Mathieu; Grothier, Thomas; Hazelton, Warren; Manzoor, Somayya; Costu, Eren; Taylor, Julia; Bulek, Anna; Srivastava, Saket; Gannon, Isaac; Jha, Ram; Gealy, Rosalind; Stanczuk, Lukas; Rizou, Tatiana; Robson, Mathew; El-Kholy, Mohamed; Baldan, Vania; Righi, Matteo; Sillibourne, James; Thomas, Simon; Onuoha, Shimobi; Cordoba, Shaun; Pule, Martin 分享 收藏
Designer Small-Molecule Control System Based on Minocycline-Induced Disruption of Protein-Protein Interaction Jha, Ram; Kinna, Alexander; Hotblack, Alastair; Bughda, Reyisa; Bulek, Anna; Gannon, Isaac; Ilca, Tudor; Allen, Christopher; Lamb, Katarina; Dolor, Abigail; Scott, Ian; Parekh, Farhaan; Sillibourne, James; Cordoba, Shaun; Onuoha, Shimobi; Thomas, Simon; Ferrari, Mathieu; Pule, Martin 分享 收藏
AKT inhibition generates potent polyfunctional clinical grade AUTO1 CAR T-cells, enhancing function and survival AKT抑制产生有效的多功能临床级AUTO1 car-t细胞，增强功能和生存 Mehra, Vedika; Agliardi, Giulia; Pinto, Juliana Dias Alves; Shafat, Manar S.; Garai, Amaia Cadinanos; Green, Louisa; Hotblack, Alastair; Vargas, Fred Arce; Peggs, Karl S.; van der Waart, Anniek B.; Dolstra, Harry; Pule, Martin A.; Roddie, Claire 分享 收藏
Transcriptional signatures associated with persisting CD19 CAR-T cells in children with leukemia 与白血病儿童中持续存在的CD19 car-t细胞相关的转录特征 Anderson, Nathaniel D.; Birch, Jack; Accogli, Theo; Criado, Ignacio; Khabirova, Eleonora; Parks, Conor; Wood, Yvette; Young, Matthew D.; Porter, Tarryn; Richardson, Rachel; Albon, Sarah J.; Popova, Bilyana; Lopes, Andre; Wynn, Robert; Hough, Rachael; Gohil, Satyen H.; Pule, Martin; Amrolia, Persis J.; Behjati, Sam; Ghorashian, Sara 分享 收藏
Dual targeting of CD19 and CD22 against B-ALL a novel-sensitivity aCD22 CAR Kokalaki, Evangelia; Ma, Biao; Ferrari, Mathieu; Grothier, Thomas; Hazelton, Warren; Manzoor, Somayya; Costu, Eren; Taylor, Julia; Bulek, Anna; Srivastava, Saket; Gannon, Isaac; Jha, Ram; Gealy, Rosalind; Stanczuk, Lukas; Rizou, Tatiana; Robson, Mathew; El-Kholy, Mohamed; Baldan, Vania; Righi, Matteo; Sillibourne, James; Thomas, Simon; Onuoha, Shimobi; Cordoba, Shaun; Pule, Martin 分享 收藏
Limited efficacy of APRIL CAR in patients with multiple myeloma indicate challenges in the use of natural ligands for CAR T-cell therapy APRIL CAR在多发性骨髓瘤患者中的有限疗效表明使用天然配体进行CAR T细胞治疗的挑战 Lee, Lydia; Lim, Wen Chean; Galas-Filipowicz, Daria; Fung, Kent; Taylor, Julia; Patel, Dominic; Akbar, Zulaikha; Mediavilla, Elena Alvarez; Wawrzyniecka, Patrycja; Shome, Debarati; Reijmers, Rogier M.; Gregg, Trillian; Wood, Leigh; Day, William; Cerec, Virginie; Ferrari, Mathieu; Thomas, Simon; Cordoba, Shaun; Onuoha, Shimobi; Khokhar, Nushmia; Peddareddigari, Vijay; Al-Hajj, Muhammad; Cavet, Jim; Zweegman, Sonja; Rodriguez-Justo, Manuel; Yong, Kwee; Pule, Martin; Popat, Rakesh 分享 收藏
分享 收藏
Exploration of T cell immune responses by expression of a dominant-negative SHP1 and SHP2 Taylor, Julia; Bulek, Anna; Gannon, Isaac; Robson, Mathew; Kokalaki, Evangelia; Grothier, Thomas; McKenzie, Callum; El-Kholy, Mohamed; Stavrou, Maria; Traynor-White, Charlotte; Lim, Wen Chean; Panagiotou, Panagiota; Srivastava, Saket; Baldan, Vania; Sillibourne, James; Ferrari, Mathieu; Pule, Martin; Thomas, Simon 分享 收藏
Novel Fas-TNFR chimeras that prevent Fas ligand-mediated kill and signal synergistically to enhance CAR T cell efficacy McKenzie, Callum; El-Kholy, Mohamed; Parekh, Farhaan; Robson, Mathew; Lamb, Katarina; Allen, Christopher; Sillibourne, James; Cordoba, Shaun; Thomas, Simon; Pule, Martin 分享 收藏
Activation priming and cytokine polyfunctionality modulate the enhanced functionality of low-affinity CD19 CAR T cells 激活引发和细胞因子多功能性调节低亲和力CD19 CAR T细胞的增强功能 Michelozzi, Ilaria M.; Gomez-Castaneda, Eduardo; Pohle, Ruben V. C.; Rodriguez, Ferran Cardoso; Sufi, Jahangir; Costa, Pau Puigdevall; Subramaniyam, Meera; Kirtsios, Efstratios; Eddaoudi, Ayad; Wu, Si Wei; Guvenel, Aleks; Fisher, Jonathan; Ghorashian, Sara; Pule, Martin A.; Tape, Christopher J.; Castellano, Sergi; Amroia, Persis J.; Giustacchini, Alice 分享 收藏
Paediatric Strategy Forum for medicinal product development of chimeric antigen receptor T-cells in children and adolescents with cancer ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration 儿童和青少年癌症患者嵌合抗原受体T细胞药物产品开发儿科战略论坛与欧洲药品管理局合作，食品和药物管理局参与加速 Pearson, Andrew D. J.; Rossig, Claudia; Mackall, Crystal; Shah, Nirali N.; Baruchel, Andre; Reaman, Gregory; Ricafort, Rosanna; Heenen, Delphine; Bassan, Abraham; Berntgen, Michael; Bird, Nick; Bleickardt, Eric; Bouchkouj, Najat; Bross, Peter; Brownstein, Carrie; Cohen, Sarah Beaussant; de Rojas, Teresa; Ehrlich, Lori; Fox, Elizabeth; Gottschalk, Stephen; Hanssens, Linda; Hawkins, Douglas S.; Horak, Ivan D.; Taylor, Danielle H.; Johnson, Courtney; Karres, Dominik; Ligas, Franca; Ludwinski, Donna; Mamonkin, Maksim; Marshall, Lynley; Masouleh, Behzad K.; Matloub, Yousif; Maude, Shannon; McDonough, Joe; Minard-Colin, Veronique; Norga, Koen; Nysom, Karsten; Pappo, Alberto; Pearce, Laura; Pieters, Rob; Pule, Martin; Quintas-Cardama, Alfonso; Richardson, Nick; Schuessler-Lenz, Martina; Scobie, Nicole; Sersch, Martina A.; Smith, Malcolm A.; Sterba, Jaroslav; Tasian, Sarah K.; Weigel, Brenda; Weiner, Susan L.; Zwaan, Christian Michel; Lesa, Giovanni; Vassal, Gilles 分享 收藏
.png){kind=icon}
.png){kind=icon}
.png)
BLOOD.png)
.png){kind=icon}
分享.png){kind=icon}
收藏
OAAI