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K

Katerina Politi

yaleResearch Fellow
H指数:54
被引数:2.0万

个人简介

Katerina Politi studied Biology at the University of Pavia in Italy. She then moved to New York, where she obtained her PhD in Genetics and Development working with Argiris Efstratiadis at Columbia University. Following graduate school, she joined Harold Varmus's lab at Memorial Sloan-Kettering Cancer Center and began her work on the molecular basis of lung cancer. She continues this work at Yale as a Professor in the Department of Pathology and Yale Cancer Center.

教育背景

  • 2003.12

    Columbia University PhD Genetics and Development

工作经历

  • 2008.12

    Memorial Sloan-Kettering Cancer Center

    Research Fellow

  • 2010.12

    Memorial Sloan-Kettering Cancer Center

    Senior Research Scientist

  • 2003.12

    Columbia University

    Postdoctoral Research Scientist

荣誉奖项

暂无内容

Epigenetic priming promotes tyrosine kinase inhibitor resistance and oncogene amplification

表观遗传启动促进酪氨酸激酶抑制剂耐药性和癌基因扩增

Nature Structural & Molecular Biology
IF10.1
2025-10-230
OAAI
Rebecca M. Starble; Eric G. Sun; Rana Gbyli; Jonathan Radda; Jiuwei Lu; Tyler B. Jensen; Ning Sun; Nelli Khudaverdyan; Ting Zhao; Bomiao Hu; Mary Ann Melnick; Shuai Zhao; Nitin Roper; Gang Greg Wang; Alan J. Tackett; Yinsheng Wang; Jikui Song; Katerina Politi; Siyuan Wang; Andrew Z. Xiao
The Polycomb Protein EED Constrains the SCLC Neuroendocrine Phenotype and Drives Lung Cancer Histological Transformation

多梳蛋白EED限制小细胞肺癌神经内分泌表型并驱动肺癌组织学转化

Journal of Thoracic Oncology
IF20.8
2025-08-290
PRE
Yixiang Li; Yasmin N. Laimon; Hyeonseo Cho; Marina Vivero; Gabriel Roberti De Oliveira; Andrew Delcea; Yuting Chen; Yavuz Durmaz; Xintao Qiu; Jakub Berchuck; Roderick T. Bronson; Shuqiang Li; Hongbin Ji; Katerina Politi; Matthew Freedman; Henry W. Long; Sabina Signoretti; Matthew G. Oser
Advances in Lung Cancer Basic and Translational Research in 2025 – Overview and Perspectives Focusing on NSCLC

2025年肺癌基础与转化研究进展——聚焦NSCLC的概述与展望

Journal of Thoracic Oncology
IF20.8
2025-06-030
PRE
Celine Mascaux; Triparna Sen; Montse Sanchez-Cespedes; Sandra Ortiz-Cuaran; Yohan Bossé; Floris Dammeijer; Milena Cavic; Martin P. Barr; Surein Arulananda; Ricardo Armisen; Alice H. Berger; Fabrizio Bianchi; David P. Carbone; Ferdinando Cerciello; William W. Lockwood; Tetsuya Mitsudomi; Shuta Ohara; Katerina Politi; Sida Qin; Laila C. Roisman; Robert Samstein; Ferdinandos Skoulidis; Aaron C. Tan; Anish Thomas; Jianjun Zhang; Murry W. Wynes; Thomas John; Ming Sound Tsao
Hypoxia is linked to acquired resistance to immune checkpoint inhibitors in lung cancer

缺氧与肺癌对免疫检查点抑制剂的获得性耐药有关

JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2024-11-251
PRE
Robles-Oteiza, Camila; Hastings, Katherine; Choi, Jungmin; Sirois, Isabelle; Ravi, Arvind; Exposito, Francisco; de Miguel, Fernando; Knight, James R.; Lopez-Giraldez, Francesc; Choi, Hyejin; Socci, Nicholas D.; Merghoub, Taha; Awad, Mark; Getz, Gad; Gainor, Justin; Hellmann, Matthew D.; Caron, Etienne; Kaech, Susan M.; Politi, Katerina
Mechanisms and clinical activity of an EGFR and HER2 exon 20-selective kinase inhibitor in non-small cell lung cancer (vol 24, pg 638, 2018)
NATURE MEDICINE
IF50
2024-08-200
OA
Robichaux, Jacqulyne P.; Elamin, Yasir Y.; Tan, Zhi; Carter, Brett W.; Zhang, Shuxing; Liu, Shengwu; Li, Shuai; Chen, Ting; Poteete, Alissa; Estrada-Bernal, Adriana; Le, Anh T.; Truini, Anna; Nilsson, Monique B.; Sun, Huiying; Roarty, Emily; Goldberg, Sarah B.; Brahmer, Julie R.; Altan, Mehmet; Lu, Charles; Papadimitrakopoulou, Vassiliki; Politi, Katerina; Doebele, Robert C.; Wong, Kwok-Kin; Heymach, John V.
Oncogenic context shapes the fitness landscape of tumor suppression
NATURE COMMUNICATIONS
IF15.7
2023-10-125
OAAI
Blair, Lily M.; Juan, Joseph M.; Sebastian, Lafia; Tran, Vy B.; Nie, Wensheng; Wall, Gregory D.; Gerceker, Mehmet; Lai, Ian K.; Apilado, Edwin A.; Grenot, Gabriel; Amar, David; Foggetti, Giorgia; Do Carmo, Mariana; Ugur, Zeynep; Deng, Debbie; Chenchik, Alex; Paz Zafra, Maria; Dow, Lukas E.; Politi, Katerina; MacQuitty, Jonathan J.; Petrov, Dmitri A.; Winslow, Monte M.; Rosen, Michael J.; Winters, Ian P.
Autologous humanized PDX modeling for immuno-oncology recapitulates features of the human tumor microenvironment

用于免疫肿瘤学的自体人源化PDX建模概括了人类肿瘤微环境的特征

JOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
2023-07-247
OAAI
Chiorazzi, Michael; Martinek, Jan; Krasnick, Bradley; Zheng, Yunjiang; Robbins, Keenan J.; Qu, Rihao; Kaufmann, Gabriel; Skidmore, Zachary; Juric, Melani; Henze, Laura A.; Brosecke, Frederic; Adonyi, Adam; Zhao, Jun; Shan, Liang; Sefik, Esen; Mudd, Jacqueline; Bi, Ye; Goedegebuure, S. Peter; Griffith, Malachi; Griffith, Obi; Oyedeji, Abimbola; Fertuzinhos, Sofia; Garcia-Milian, Rolando; Boffa, Daniel; Detterbeck, Frank; Dhanasopon, Andrew; Blasberg, Justin; Judson, Benjamin; Gettinger, Scott; Politi, Katerina; Kluger, Yuval; Palucka, Karolina; Fields, Ryan C.; Flavell, Richard A.
PTEN Loss Confers Resistance to Anti-PD-1 Therapy in Non-Small Cell Lung Cancer by Increasing Tumor Infiltration of Regulatory T Cells
CANCER RESEARCH
IF16.6
2023-06-1312
OA
Exposito, Francisco; Redrado, Miriam; Houry, Maeva; Hastings, Katherine; Molero-Abraham, Magdalena; Lozano, Teresa; Solorzano, Jose Luis; Sanz-Ortega, Julian; Adradas, Vera; Amat, Ramon; Redin, Esther; Leon, Sergio; Legarra, Naroa; Garcia, Javier; Serrano, Diego; Valencia, Karmele; Robles-Oteiza, Camila; Foggetti, Giorgia; Otegui, Nerea; Felip, Enriqueta; Lasarte, Juan J.; Paz-Ares, Luis; Zugazagoitia, Jon; Politi, Katerina; Montuenga, Luis; Calvo, Alfonso
Autologous humanized PDX modeling for immuno-oncology recapitulates the human tumor microenvironment
CANCER RESEARCH
IF16.6
2023-04-040
PRE
Chiorazzi, Michael; Martinek, Jan; Krasnick, Bradley; Zheng, Yunjiang; Robbins, Keenan; Qu, Rihao; Kaufmann, Gabriel; Skidmore, Zachary; Henze, Laura; Brosecke, Frederic; Adonyi, Adam; Zhao, Jun; Shan, Liang; Sefik, Esen; Mudd, Jacqueline; Bi, Ye; Goedegebuure, S. Peter; Griffith, Malachi; Griffith, Obi; Oyedeji, Abimbola; Fertuzinhos, Sofia; Garcia-Milian, Roland; Boffa, Daniel; Detterbeck, Frank; Dhanasopon, Andrew; Blasberg, Justin; Judson, Benjamin; Gettinger, Scott; Politi, Katerina; Kluger, Yuval; Palucka, A. Karolina; Fields, Ryan; Flavell, Richard A.

研究方向

Lung NeoplasmsCell TransformationNeoplasticMolecular Targeted Therapy
S
Scott Gettinger
H 指数:83论文数:635被引数:6.3万
H
Harold Varmus
H 指数:129论文数:751被引数:7.7万
S
Sarah B. Goldberg
H 指数:48论文数:490被引数:1.2万
R
Robert Homer
H 指数:92论文数:613被引数:3.7万
G
Giorgia Foggetti
H 指数:13论文数:95被引数:638
W
William Pao
H 指数:112论文数:822被引数:6.6万
V
Valentina Pirazzoli
H 指数:11论文数:89被引数:1,880
C
Camila Robles-Oteíza
H 指数:9论文数:109被引数:387
K
Katherine Hastings
H 指数:9论文数:67被引数:2,086
M
Mary Ann Melnick
H 指数:11论文数:161被引数:2,117