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Safety and efficacy of trifluridine/tipiracil plus /- bevacizumab plus XB2001 (anti-IL-1α antibody): a single-center phase 1 trial 三氟尿idine/替吡拉塞联合/或贝伐珠单抗联合XB2001(抗-IL-1α抗体)的安全性与有效性:一项单中心1期临床试验 Thibaudin, Marion; Roussot, Nicolas; Burlot, Chloe; Schmitt, Antonin; Vincent, Julie; Tharin, Zoe; Bengrine, Leila; Bellio, Helene; Bertaut, Aurelie; Hampe, Lea; Daumoine, Susy; Rederstorff, Emilie; Peroz, Morgane; Huppe, Titouan; Derangere, Valentin; Rageot, David; Simard, John; Truntzer, Caroline; Fumet, Jean David; Ghiringhelli, Francois 分享 收藏
Deep Multiple Instance Learning Model to Predict Outcome of Pancreatic Cancer Following Surgery 深度多实例学习模型预测胰腺癌术后预后 Truntzer, Caroline; Ouahbi, Dina; Huppe, Titouan; Rageot, David; Ilie, Alis; Molimard, Chloe; Beltjens, Francoise; Bergeron, Anthony; Vienot, Angelique; Borg, Christophe; Monnien, Franck; Bibeau, Frederic; Derangere, Valentin; Ghiringhelli, Francois 分享 收藏
Real-world prevalence, treatment and survival of high risk early breast cancer, with mandatory testing of gBRCA1/2 mutation according to the OlympiA trial inclusion criteria: Data from a population-based registry 根据OlympiA试验纳入标准强制检测gBRCA1/2突变的高风险早期乳腺癌的真实世界患病率,治疗和生存率: 来自基于人群的注册表的数据 Ladoire, Sylvain; Kamga, Ariane Mamguem; Galland, Loick; Desmoulins, Isabelle; Mayeur, Didier; Kaderbhai, Coureche; Ilie, Silvia Mihaelia; Hennequin, Audrey; Jankowski, Clementine; Albuisson, Juliette; Nambot, Sophie; Coutant, Charles; Arnould, Laurent; Reda, Manon; Truntzer, Caroline; Dabakuyo, Sandrine 分享 收藏
The DAV132 colon-targeted adsorbent does not interfere with plasma concentrations of antibiotics but prevents antibiotic-related dysbiosis: a randomized phase I trial in healthy volunteers DAV132结肠靶向吸附剂不会干扰抗生素的血浆浓度,但可预防抗生素相关的生态失调: 一项针对健康志愿者的随机I期试验 Messaoudene, Meriem; Ferreira, Stephanie; Saint-Lu, Nathalie; Ponce, Mayra; Truntzer, Caroline; Boidot, Romain; Le Bescop, Clement; Loppinet, Thomas; Corbel, Tanguy; Feger, Celine; Bertrand, Karine; Elkrief, Arielle; Isaksen, Morten; Vitry, Fabien; Sablier-Gallis, Frederique; Andremont, Antoine; Bod, Lloyd; Ghiringhelli, Francois; de Gunzburg, Jean; Routy, Bertrand 分享 收藏
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Case report: Immune response characterization of a pseudoprogression in a PD-L1-negative, TMB-low, KEAP1/STK11 co-mutated metastatic NSCLC Roussot, Nicolas; Thibaudin, Marion; Fumet, Jean-David; Daumoine, Susy; Hampe, Lea; Rebe, Cedric; Limagne, Emeric; Lagrange, Aurelie; Herreros, Victor; Lecuelle, Julie; Mananet, Hugo; Ilie, Alis; Rageot, David; Boidot, Romain; Goussot, Vincent; Comte, Anthony; Jacob, Pierre; Beltjens, Francoise; Bergeron, Anthony; Charon-Barra, Celine; Arnould, Laurent; Derangere, Valentin; Ladoire, Sylvain; Truntzer, Caroline; Ghiringhelli, Francois 分享 收藏
Machine learning evaluation of immune in fi ltrate through digital tumour score allows prediction of survival outcome in a pooled analysis of three international stage III colon cancer cohorts 通过数字肿瘤评分对免疫功能进行机器学习评估,可以在三个国际III期结肠癌队列的汇总分析中预测生存结果 Lecuelle, Julie; Truntzer, Caroline; Basile, Debora; Laghi, Luigi; Greco, Luana; Ilie, Alis; Rageot, David; Emile, Jean-Francois; Bibeau, Frederic; Taieb, Julien; Derangere, Valentin; Lepage, Come; Ghiringhelli, Francois 分享 收藏
Phase I dose-escalation study of trifluridine/tipiracil plus XB2001 and bevacizumab in chemorefractory advanced colorectal cancer: The TASKIN study Roussot, N.; Thibaudin, M.; Burlot, C.; Schmitt, A.; Hervieu, A.; Bellio, H.; Fraisse, C.; Lagrange, A.; Tharin, V. Z.; Zanetta, S.; Vincent, J.; Lefevre, L. Bengrine; Hennequin, A.; Constantin, G.; Rederstorff, E.; Bertaut, A.; Derangere, V.; Truntzer, C.; Fumet, J-D.; Ghiringhelli, F. 分享 收藏
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First-line durvalumab and tremelimumab with chemotherapy in RAS-mutated metastatic colorectal cancer: a phase 1b-2 trial Thibaudin, Marion; Fumet, Jean-David; Limagne, Emeric; Hampe, Lea; Daumoine, Susy; Derangere, Valentin; Laheurte, Caroline; Adotevi, Olivier; Truntzer, Caroline; Ghiringhelli, Francois 分享 收藏
Deep learning uncovers morphological patterns of YAP1/TEAD activity related to disease aggressiveness in cancer patients Schmauch, Benoit; Cabeli, Vincent; Darwiche-Domingues, Omar; Le Douget, Jean-Eudes; Hardy, Alexandra; Belbahri, Reda; Maussion, Charles; Romagnoni, Alberto; Eckstein, Markus; Fuchs, Florian; Swalduz, Aurelie; Lantuejoul, Sylvie; Crochet, Hugo; Ghiringhelli, Francois; Derangere, Valentin; Truntzer, Caroline; Pass, Harvey; Moreira, Andre; Chiriboga, Luis; Zheng, Yuanning; Ozawa, Michael; Howitt, Brooke; Gevaert, Olivier; Girard, Nicolas; Rexhepaj, Elton; Valtingojer, Iris; Debussche, Laurent; Durand, Eric; Classe, Marion; Von Loga, Katharina; Pronier, Elodie; Cesaroni, Matteo 分享 收藏
CD3-CD8 immune score associated with a clinical score stratifies PDAC prognosis regardless of adjuvant or neoadjuvant chemotherapy Schoumacher, Coralie; Derangere, Valentin; Gaudilliere-Le Dain, Gwladys; Huppe, Titouan; Rageot, David; Ilie, Alis; Vienot, Angelique; Borg, Christophe; Monnien, Franck; Bibeau, Frederic; Truntzer, Caroline; Ghiringhelli, Francois 分享 收藏
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First-line durvalumab and tremelimumab with chemotherapy in RAS-mutated metastatic colorectal cancer: a phase 1b/2 trial 一线durvalumab和tremelimumab联合化疗治疗RAS突变的转移性结直肠癌: 1b/2期试验 Thibaudin, Marion; Fumet, Jean-David; Chibaudel, Benoist; Bennouna, Jaafar; Borg, Christophe; Martin-Babau, Jerome; Cohen, Romain; Fonck, Marianne; Taieb, Julien; Limagne, Emeric; Blanc, Julie; Ballot, Elise; Hampe, Lea; Bon, Marjorie; Daumoine, Susy; Peroz, Morgane; Mananet, Hugo; Derangere, Valentin; Boidot, Romain; Michaud, Henri-Alexandre; Laheurte, Caroline; Adotevi, Olivier; Bertaut, Aurelie; Truntzer, Caroline; Ghiringhelli, Francois 分享 收藏
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Peroxisomal defects in microglial cells induce a disease-associated microglial signature Raas, Quentin; Tawbeh, Ali; Tahri-Joutey, Mounia; Gondcaille, Catherine; Keime, Celine; Kaiser, Romain; Trompier, Doriane; Nasser, Boubker; Leoni, Valerio; Bellanger, Emma; Boussand, Maud; Hamon, Yannick; Benani, Alexandre; Di Cara, Francesca; Truntzer, Caroline; Cherkaoui-Malki, Mustapha; Andreoletti, Pierre; Savary, Stephane 分享 收藏