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L

Lars Burdorf

united therapeutics corporation
H指数:23
被引数:1,932

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荣誉奖项

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Investigational New Drug Enabling Nonclinical Study of Xenogeneic Life-Supporting Porcine Kidneys With 10 Gene Edits (10 GE) in a Nonhuman Primate Test System

异种基因编辑猪肾脏非临床研究（10 GE）在非人灵长类动物测试系统中的新药临床试验申请

Xenotransplantation
IF4.1
2026-02-230
PRE
Daniel L. Eisenson; Alexander C. Schulick; WeiLi Chen; Michelle R. Santillan; Michael Cole; Yu Hisadome; Kasra Shirini; Du Gu; Vina Nguyen; Yusuf Ciftci; Alice Zhao; Armaan Akbar; Saghar Babadi; Amanda Maxwell; Kristina DeSmet; Marc Lorber; Leigh Peterson; Lars Burdorf; Kasinath Kuravi; Farzana Rahman; Lori Sorrells; Maria Kokkinaki; Daniel Warren; Betsy King; Russell Wesson; Hamid Rabb; June Jones; Kathleen Funk; Matthew Sturos; Muraly Puttabyatappa; Brijesh Verma; Robin Avery; Thomas Johnson III; William Clarke; Robert Brodsky; Maria Bettinotti; Avi Rosenberg; Hayato Iwase; David Ayares; Andrew Cameron; Kazuhiko Yamada
Physiology and immunology of pig-to-human decedent kidney xenotransplant

猪对人类遗体肾脏异种移植的生理学与免疫学

Nature
IF48.5
2025-11-130
PRE
Robert A. Montgomery; Jeffrey M. Stern; Farshid Fathi; Nathan Suek; Jacqueline I. Kim; Karen Khalil; Benjamin Vermette; Vasishta S. Tatapudi; Aprajita Mattoo; Edward Y. Skolnik; Ian S. Jaffe; Imad Aljabban; Tal Eitan; Shivani Bisen; Elaina P. Weldon; Valentin Goutaudier; Erwan Morgand; Fariza Mezine; Alessia Giarraputo; Idris Boudhabhay; Patrick Bruneval; Aurelie Sannier; Kevin Breen; Yasmeen S. Saad; Constanza Bay Muntnich; Simon H. Williams; Weimin Zhang; Larisa Kagermazova; Eloi Schmauch; Chandra Goparaju; Rebecca Dieter; Nikki Lawson; Amy Dandro; Ana Laura Fazio-Kroll; Lars Burdorf; David Ayares; Marc Lorber; Dorry Segev; Nicole Ali; David S. Goldfarb; Victoria Costa; Timothy Hilbert; Sapna A. Mehta; Ramin S. Herati; Harvey I. Pass; Ming Wu; Jef D. Boeke; Brendan Keating; Massimo Mangiola; Philip M. Sommer; Alexandre Loupy; Adam Griesemer; Megan Sykes
Extended survival of 9-and 10-gene-edited pig heart xenografts with ischemia minimization and CD154 costimulation blockade-based immunosuppression
JOURNAL OF HEART AND LUNG TRANSPLANTATION
IF6
2024-12-012
PRE
Chaban, Ryan; Ileka, Ikechukwu; McGrath, Gannon; Kinoshita, Kohei; Habibabady, Zahra; Ma, Madelyn; Diaz, Victoria; Maenaka, Akihiro; Calhoun, Anthony; Dufault, Megan; Rosales, Ivy; Laguerre, Christiana M.; Sanatkar, Seyed-Amir; Burdorf, Lars; Ayares, David L.; Eyestone, William; Sardana, Prachi; Kuravi, Kasinath; Sorrells, Lori; Lederman, Seth; Lucas, Caroline G.; Prather, Randall S.; Wells, Kevin D.; Whitworth, Kristin M.; Cooper, David K. C.; Pierson III, Richard N.
Consistent survival in consecutive cases of life-supporting porcine kidney xenotransplantation using 10GE source pigs

使用10GE来源的猪进行维持生命的猪肾异种移植的连续病例中的一致存活率

NATURE COMMUNICATIONS
IF15.7
2024-04-188
OAAI
Eisenson, Daniel; Hisadome, Yu; Santillan, Michelle; Iwase, Hayato; Chen, WeiLi; Shimizu, Akira; Schulick, Alex; Gu, Du; Akbar, Armaan; Zhou, Alice; Koenig, Kristy; Kuravi, Kasinath; Rahman, Farzana; Sorrells, Lori; Burdorf, Lars; DeSmet, Kristina; Warren, Daniel; Peterson, Leigh; Lorber, Marc; Ayares, David; Cameron, Andrew; Yamada, Kazuhiko
Expression of human thrombomodulin by GalTKO.hCD46 pigs modulates coagulation cascade activation by endothelial cells and during ex vivo lung perfusion with human blood
XENOTRANSPLANTATION
IF4.1
2023-09-284
PRE
Burdorf, Lars; Gao, Zhuo; Riner, Andrea; Sievert, Evelyn; Harris, Donald G.; Kuravi, Kasinath V.; Morrill, Benson H.; Habibabady, Zahra; Rybak, Elana; Dahi, Siamak; Zhang, Tianshu; Schwartz, Evan; Kang, Elizabeth; Cheng, Xiangfei; Esmon, Charles T.; Phelps, Carol J.; Ayares, David L.; Pierson III, Richard N.; Azimzadeh, Agnes M.
Increased human complement pathway regulatory protein gene dose is associated with increased endothelial expression and prolonged survival during ex-vivo perfusion of GTKO pig lungs with human blood
XENOTRANSPLANTATION
IF4.1
2023-07-282
PRE
Chaban, Ryan; McGrath, Gannon; Habibabady, Zahra; Rosales, Ivy; Burdorf, Lars; Ayares, David L. L.; Rybak, Elana; Zhang, Tianshu; Harris, Donald G. G.; Dahi, Siamak; Ali, Franchesca; Parsell, Dawn M. M.; Braileanu, Gheorghe; Cheng, Xiangfei; Sievert, Evelyn; Phelps, Carol; Azimzadeh, Agnes M. M.; Pierson, Richard N. N.
Pig-to-human heart xenotransplantation in two recently deceased human recipients
NATURE MEDICINE
IF50
2023-07-2456
PRE
Moazami, Nader; Stern, Jeffrey M. M.; Khalil, Karen; Kim, Jacqueline I.; Narula, Navneet; Mangiola, Massimo; Weldon, Elaina P. P.; Kagermazova, Larisa; James, Les; Lawson, Nikki; Piper, Greta L. L.; Sommer, Philip M. M.; Reyentovich, Alex; Bamira, Daniel; Saraon, Tajinderpal; Kadosh, Bernard S. S.; DiVita, Michael; Goldberg, Randal I. I.; Hussain, Syed T. T.; Chan, Justin S.; Ngai, Jennie; Jan, Thomas M.; Ali, Nicole M. M.; Tatapudi, Vasishta S. S.; Segev, Dorry L. L.; Bisen, Shivani; Jaffe, Ian S. S.; Piegari, Benjamin; Kowalski, Haley; Kokkinaki, Maria; Monahan, Jeffrey; Sorrells, Lori; Burdorf, Lars; Boeke, Jef D. D.; Pass, Harvey; Goparaju, Chandra; Keating, Brendan; Ayares, David; Lorber, Marc; Griesemer, Adam; Mehta, Sapna A. A.; Smith, Deane E. E.; Montgomery, Robert A. A.
Results of Two Cases of Pig-to-Human Kidney Xenotransplantation
NEW ENGLAND JOURNAL OF MEDICINE
IF78.5
2022-05-19219
OA
Montgomery, Robert A.; Stern, Jeffrey M.; Lonze, Bonnie E.; Tatapudi, Vasishta S.; Mangiola, Massimo; Wu, Ming; Weldon, Elaina; Lawson, Nikki; Deterville, Cecilia; Dieter, Rebecca A.; Sullivan, Brigitte; Boulton, Gabriella; Parent, Brendan; Piper, Greta; Sommer, Philip; Cawthon, Samantha; Duggan, Erin; Ayares, David; Dandro, Amy; Fazio-Kroll, Ana; Kokkinaki, Maria; Burdorf, Lars; Lorber, Marc; Boeke, Jef D.; Pass, Harvey; Keating, Brendan; Griesemer, Adam; Ali, Nicole M.; Mehta, Sapna A.; Stewart, Zoe A.

研究方向

暂未获取到该数据
R
Richard N. Pierson
H 指数:80论文数:517被引数:2.3万
D
David Ayares
H 指数:59论文数:409被引数:1.5万
A
Agnes M. Azimzadeh
H 指数:37论文数:194被引数:4,157
X
Xiangfei Cheng
H 指数:16论文数:75被引数:997
H 指数:0论文数:54被引数:271
D
Donald G. Harris
H 指数:23论文数:111被引数:1,235
G
Gheorghe Braileanu
H 指数:15论文数:88被引数:885
E
Evelyn Sievert
H 指数:9论文数:28被引数:448
D
Dawn Parsell
H 指数:13论文数:75被引数:641
C
Carol J. Phelps
H 指数:28论文数:132被引数:5,126