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K

Konrad Aden

christian-albrechts-university and university hospital schleswig-holstein
H指数:32
被引数:3,708

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Systematic Screening of Tryptophan Metabolism Identifies Site- and Microbiota-Dependent Signatures of Tryptophan Utilization in Experimental Colitis

系统筛选色氨酸代谢识别实验性结肠炎中色氨酸利用的位点依赖性和微生物群依赖性特征

International Journal of Tryptophan Research
IF4.1
2026-08-110
PRE
Lina Wehkamp; Abrar I. Alsaadi; Danielle M. M. Harris; Meiping Yu; Taous Mekdoud; Johanna Bornhäuser; Eva Springer; Clara Gilloteau; Anant A. Pothakamury; Jaclyn D. Smith; Brenita C. Jenkins; Martina Guggeis; Felix Sommer; Silvio Waschina; Philip Rosenstiel; Stefan Schreiber; Melanie R. McReynolds; Konrad Aden
Tracing NAD+ metabolism uncovers adaptive coordination between host and microbiome during colitis

追踪NAD+代谢揭示结肠炎期间宿主与微生物群的适应性协调

Cell Reports
IF6.9
2026-07-250
OAAI
Abrar I. Alsaadi; Lina Wehkamp; Anant A. Pothakamury; Mahmoud S. Yahia; Praveena Prasad; Clara Gilloteau; Jaedon Sadler; Jaclyn D. Smith; Brenita C. Jenkins; Garret S. Diven; Johanna Bornhäuser; Taous Mekdoud; Shuchang Tian; Philip Rosenstiel; Stefan Schreiber; Jordan E. Bisanz; Konrad Aden; Melanie R. McReynolds
Single-cell longitudinal profiling of peripheral blood identifies shared and therapy-specific immune signatures of early remission in ulcerative colitis

单细胞纵向分析外周血可识别溃疡性结肠炎早期缓解期共有的和疗法特异性的免疫特征

Journal of Crohns & Colitis
IF8.7
2026-01-010
PRE
Bernardes, J. P.; Li Yim, A.; Schulte-Schrepping, J.; Tran, F.; Oldenburg, L.; De Jonge, W.; Aden, K.; D'haens, G.; Vetrano, S.; Schultze, J. L.; Schreiber, S. W.; Rosenstiel, P.
Systematic screening of tryptophan metabolism identifies site- and microbial-specific signatures of tryptophan utilization in experimental colitis

系统性筛选色氨酸代谢，鉴定实验性结肠炎中色氨酸利用的位点特异性和微生物特异性特征

Journal of Crohns & Colitis
IF8.7
2026-01-010
PRE
Welz, L.; Alsaadi, A.; Harris, D.; Yu, M.; Mekdoud, T.; Bornhaeuser, J.; Springer, E.; Gilloteau, C.; Pothakamury, A.; Smith, J.; Jenkins, B.; Sommer, F.; Waschina, S.; Rosenstiel, P.; Schreiber, S. W.; McReynolds, M.; Aden, K.
Biomarker-informed therapy guidance improved clinical outcomes of anti-tumour necrosis factor treatment in patients with inflammatory bowel disease in a multi-centre, randomized, controlled, open-label, prospective clinical trial (GUIDE-IBD)

生物标志物指导的疗法改善了炎症性肠病患者抗肿瘤坏死因子治疗的临床结局：一项多中心、随机、对照、开放标签、前瞻性临床试验（GUIDE-IBD）

Journal of Crohns & Colitis
IF8.7
2026-01-010
PRE
Tran, F.; Aden, K.; Bernardes, J. P.; Imm, C.; Kovar, C.; Rudesheim, S.; Dankowski, T.; Florea, M.; Stallbaum, F.; Nikolaus, S.; Szymczak, S.; Hofmann, U.; Lehr, T.; Schwab, M.; Dempfle, A.; Huber, S.; Wiestler, M.; Seidler, U.; Rosenstiel, P.; Schreiber, S. W.
Type I and II interferon blood signatures correlate with ultrasound markers of intestinal fibrostenosis and predict surgical outcomes in Crohn's disease

I型和II型干扰素血液特征与克罗恩病肠道纤维狭窄的超声标志物相关，并能预测手术结局

Journal of Crohns & Colitis
IF8.7
2026-01-010
PRE
Nasehi, F.; Blomer, L.; Mishra, N.; Kimmig, F.; Bernardes, J. P.; Bourgery, M.; Wolff, C. M.; Hinrichsen, F.; Guggeis, M.; Nikolaus, S.; Lieb, W.; Franke, A.; Aden, K.; Schreiber, S. W.; Rosenstiel, P.; Tran, F.
Cross-species engraftment biases and metabolic divergence in gnotobiotic mice humanized with ulcerative colitis microbiota

跨物种移植偏倚及在接种溃疡性结肠炎微生物群的悉生小鼠中的代谢差异

Gut Microbes
IF11
2025-11-240
OAAI
Martina A. Guggeis; Nadia Andrea Andreani; Víctor A. López-Agudelo; Florian Tran; A. Samer Kadibalban; Karlis Arturs Moors; Georgios Marinos; Abdulgawaad Saboukh; Danielle Harris; Maren Falk-Paulsen; Saskia Weber-Stiehl; Lea Järke; Felix Sommer; Lina Welz; Corinna Bang; Andre Franke; Cecilia J. Chung; Christina Bronowski; Sven Schuchardt; Sven Künzel; Konrad Aden; Stefan Schreiber; Christoph Kaleta; John F. Baines; Philip Rosenstiel
Microbial metabolite indole-3-propionic acid drives mitochondrial respiration in CD4+ T cells to confer protection against intestinal inflammation

微生物代谢产物吲哚-3-丙酸驱动CD4+ T细胞线粒体呼吸，以对抗肠道炎症提供保护。

Nature Metabolism
IF20.8
2025-10-210
OA
Qing Li; Rodrigo de Oliveira Formiga; Virginie Puchois; Laura Creusot; Ahmad Haidar Ahmad; Salomé Amouyal; Márcio Augusto Campos-Ribeiro; Yining Zhao; Danielle M. M. Harris; Frederic Lasserre; Sandrine Ellero-Simatos; Hervé Guillou; Zhan Huang; Loic Brot; Yuhang Hu; Loic Chollet; Camille Danne; Cyril Scandola; Tatiana Ledent; Guillaume Chevreux; Rafael J. Argüello; Marcelo De Carvalho Bittencourt; Jessica Bettinger; Maud D’Aveni-Piney; David Moulin; Stefan Schreiber; Konrad Aden; Nathalie Rolhion; Marie-Laure Michel; Timothy Wai; Harry Sokol
Atg16l1 and Xbp1 cooperatively protect from transcription-associated mutagenesis and small intestinal carcinogenesis

Atg16l1和Xbp1协同保护免受转录相关突变和小肠致癌作用

Oncogene
IF7.3
2025-10-070
OA
Nassim Kakavand; Hang Xiang; Georg Laue; Taous Mekdoud; Lina Welz; Miguel Gomes Silva; Joana P. Bernardes; Go Ito; Silke van den Bossche; Julia Kugler; Florian Tran; Alexander Ossysek; Simon Imm; Finn Hinrichsen; Moritz Jesinghaus; Arthur Kaser; Richard Blumberg; Timon E. Adolph; Stefan Schreiber; Markus Tschurtschenthaler; Philip Rosenstiel; Konrad Aden
987e: BIOMARKER-INFORMED THERAPY GUIDANCE IMPROVED CLINICAL OUTCOMES OF ANTI-TNF TREATMENT IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE IN A MULTI-CENTER, RANDOMIZED, OPEN-LABEL, PROSPECTIVE CLINICAL TRIAL (GUIDE-IBD)

987e: 生物标志物指导的疗法改善了炎症性肠病患者抗-TNF治疗的临床结局，该研究在一项多中心、随机、开放标签、前瞻性临床试验（GUIDE-IBD）中进行。

Gastroenterology
IF25.1
2025-07-030
PRE
Florian Tran; Konrad Aden; Joana P. Bernardes; Charlot Jäckel; Christina Kovar; Simeon Rüdesheim; Marina Florea; Franziska Stallbaum; Florian Schrinner; Susanna Nikolaus; Walter Mätzler; Andre Franke; Silke Szymczak; Ute Hofmann; Thorsten Lehr; Matthias Schwab; Astrid Dempfle; Samuel Huber; Miriam Wiestler; Ursula Seidler; Stefan Schreiber
Fecal metaproteomics enables functional characterization of remission in patients with inflammatory bowel disease

粪便元蛋白质组学能够实现炎症性肠病患者缓解期的功能表征

proteomics
IF2.8
2025-06-010
OA
Wolf, Maximilian; Lange, Julian; Benndorf, Dirk; Welz, Lina; Nikolaus, Susanna; Siever, Laura Katharina; Tran, Florian; Schallert, Kay; Hellwig, Patrick; Schreiber, Stefan; Gunzer, Matthias; Rosenstiel, Philip; Reichl, Udo; Adolph, Timon; Jukic, Almina; Aden, Konrad; Heyer, Robert

研究方向

暂未获取到该数据
P
Philip Rosenstiel
H 指数:132论文数:882被引数:8.4万
F
Florian Tran
H 指数:30论文数:153被引数:5,874
S
Stefan Schreiber
H 指数:192论文数:1,867被引数:16.9万
L
Lina Welz
H 指数:8论文数:51被引数:516
S
Susanna Nikolaus
H 指数:53论文数:190被引数:1.3万
A
André Franke
H 指数:152论文数:1,163被引数:10.2万
S
Silvio Waschina
H 指数:26论文数:115被引数:2,905
J
Johannes Bethge
H 指数:14论文数:84被引数:2,541
N
Neha Mishra
H 指数:14论文数:56被引数:1,504
A
Arthur Kaser
H 指数:81论文数:373被引数:2.9万