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Bernhard Hube

Leibniz Institute for Natural Product Research and Infection Biology Hans Knoell Institute
H指数:97
被引数:3.1万

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Local albumin excess exacerbates Candida albicans-induced inflammasome activation linked with hyperinflammation during vulvovaginal candidiasis

局部白蛋白过剩加剧外阴阴道假丝酵母菌病期间假丝酵母菌诱导的炎症小体激活，并与过度炎症相关

Nature Communications
IF15.7
2026-10-290
OAAI
Sophie Austermeier; Kar On Cheng; Axel Dietschmann; Gianluca Vascelli; Dolly E. Montaño; Sophia U. J. Hitzler; Kira S. Skurk; Candela Fernández-Fernández; Saloni Saloni; Stefanie Westermann; Martin Jaeger; Nadja Jablonowski; Stephanie Wisgott; Osama Elshafee; Chiara Brachelente; Dennis M. de Graaf; Tomasz Próchnicki; Eicke Latz; Stefan Wirtz; Christoph Becker; Giorgia Renga; Vasileios Oikonomou; Bernhard Hube; Gilbert G. G. Donders; Marina Pekmezovic; Teresa Zelante; Mark S. Gresnigt
Human Colitis-on-Chip Model Reveals Dual Roles of Butyrate in Epithelial and Macrophage Defense Against Candida albicans Tissue Invasion

人结肠炎芯片模型揭示丁酸盐在保护上皮细胞和巨噬细胞抵抗白色念珠菌组织侵袭中的双重作用

Small
IF12.1
2026-05-010
OAAI
Allwang, Manuel; Wipplinger, Maximilian; Akbarimoghaddam, Parastoo; Alonso-Roman, Raquel; Cseresnyes, Zoltan; Dietschmann, Axel; Wegner, Valentin; Feile, Adrian; Bachelot, Yann; Warschinke, Maria; Hassan, Mohamed I. Abdelwahab; Mittag, Sonnhild; Huber, Otmar; Hube, Bernhard; Gresnigt, Mark S.; Figge, Marc Thilo; Mosig, Alexander S.
DNAM-1 mediates NK-cell activation and host-pathogen interaction via direct binding to fungal cell wall proteases

DNAM-1通过直接结合真菌细胞壁蛋白酶介导NK细胞激活和宿主-病原体相互作用

Communications Biology
IF5.1
2026-04-130
OAAI
Fariha Natasha; Linda Heilig; Dominic A. Helmerich; Christian Luther; Jan Springer; Bipasa Kar; Matthias Drobny; Lydia Kasper; Carla Schuh; Marcus Dittrich; Bernhard Hube; Thomas Dandekar; Markus Sauer; Jürgen Löffler; Ulrich Terpitz
Candida albicans releases a peptide from the Rbt1 protein to promote its invasion into the gut epithelium

白色念珠菌从Rbt1蛋白中释放一种肽以促进其侵入肠道上皮。

Gut Microbes
IF11
2025-10-300
OAAI
Hervé Bègue; Amandine Ducreux; Tracy Paradis; Alicia Loiselet; Thierry Mourer; Géraldine Lucchi; Sylvie Kieffer-Jaquinod; Yohann Coute; Bernhard Hube; Ilias Theodorou; Sophie Thenet; Benjamin Gillet; Sandrine Hughes; Pierre Lapaquette; Louise Basmaciyan; Sophie Bachellier-Bassi; Christophe d'Enfert; Fabienne Bon; Frédéric Dalle
Pour some sugar on me-Environmental Candida albicans isolates and the evolution of increased pathogenicity and antifungal resistance through sugar adaptation

在我身上撒点糖-环境来源的Candida albicans分离株及其通过糖适应性增强致病性和抗真菌耐药性的进化

PLOS PATHOGENS
IF4.9
2025-10-010
PRE
Lange, Theresa; Sprague, Jakob L.; Vij, Raghav; Alonso-Roman, Raquel; Jablonowski, Nadja; Radosa, Silvia; Kruger, Thomas; Kniemeyer, Olaf; Hillmann, Falk; Brakhage, Axel A.; Allert, Stefanie; Brunke, Sascha; Hube, Bernhard
Dynamic expression of candidalysin facilitates oral colonization of Candida albicans in mice

念珠菌溶素（candidalysin）的动态表达促进了白色念珠菌（Candida albicans）在小鼠中的口腔定植。

Nature Microbiology
IF19.4
2025-09-250
OAAI
Ricardo Fróis-Martins; Julia Lagler; Tim B. Schille; Osama Elshafee; Kontxi Martinez de San Vicente; Sarah Mertens; Michelle Stokmaier; Iman Kilb; Natacha Sertour; Sophie Bachellier-Bassi; Selene Mogavero; Dominique Sanglard; Christophe d’Enfert; Bernhard Hube; Salomé LeibundGut-Landmann
Candidalysin biology and activation of host cells

白念珠菌溶素生物学及宿主细胞激活

MBIO
IF4.7
2025-06-110
OA
Lortal, Lea; Lyon, Claire M.; Sprague, Jakob L.; Sonnberger, Johannes; Paulin, Olivia K. A.; Wickramasinghe, Don N.; Richardson, Jonathan P.; Hube, Bernhard; Naglik, Julian R.
Candida albicans biofilm extracellular vesicles deliver candidalysin to epithelial cell membranes and induce host cell responses

白色念珠菌生物膜外泌体将念珠菌素传递至上皮细胞膜并诱导宿主细胞反应

INFECTION AND IMMUNITY
IF2.8
2025-05-130
OA
Lee, Sejeong; Tsavou, Antzela; Zarnowski, Robert; Pforte, Rita; Allert, Stefanie; Krueger, Thomas; Kniemeyer, Olaf; Brakhage, Axel A.; Bui, Tam T. T.; Andes, David R.; Richardson, Jonathan P.; Hube, Bernhard; Naglik, Julian R.
Essential role of hepcidin in host resistance to disseminated candidiasis

肝细胞素在宿主抵抗播散性念珠菌感染中的关键作用

CELL REPORTS
IF6.9
2025-05-010
OA
Arekar, Tanmay; Katikaneni, Divya; Kasem, Sadat; Desai, Dhruv; Acharya, Thrisha; Cole, Augustina; Khodayari, Nazli; Vaulont, Sophie; Hube, Bernhard; Nemeth, Elizabeta; Drakesmith, Alexander; Lionakis, Michail S.; Mehrad, Borna; Scindia, Yogesh
Transkingdom mechanism of MAMP generation by chitotriosidase feeds oligomeric chitin from fungal pathogens and allergens into TLR2-mediated innate immune sensing
FRONTIERS IN IMMUNOLOGY
IF5.9
2025-03-030
OAAI
Chang, Tzu-Hsuan; Gloria, Yamel Cardona; Hellmann, Margareta J.; Richardo, Timmy; Greve, Carsten Leo; Le Roy, Didier; Roger, Thierry; Bork, Francesca; Bugl, Stefanie; Jakob, Johanna; Sonnberger, Johannes; Kasper, Lydia; Hube, Bernhard; Pusch, Stefan; Gow, Neil A. R.; Sorlie, Morten; Tondervik, Anne; Moerschbacher, Bruno M.; Weber, Alexander N. R.

研究方向

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S
Sascha Brunke
H 指数:41论文数:137被引数:6,952
J
Julian R. Naglik
H 指数:58论文数:155被引数:1.2万
M
Mark S. Gresnigt
H 指数:42论文数:123被引数:7,730
I
Ilse D. Jacobsen
H 指数:51论文数:178被引数:7,933
L
Lydia Kasper
H 指数:27论文数:47被引数:3,140
D
Duncan Wilson
H 指数:37论文数:105被引数:8,636
S
Selene Mogavero
H 指数:25论文数:57被引数:3,021
S
Stefanie Allert
H 指数:16论文数:27被引数:1,077
C
Christophe d’Enfert
H 指数:66论文数:285被引数:2.0万
J
Jonathan P. Richardson
H 指数:36论文数:126被引数:5,087