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N

Neil A. Shneider

columbia university irving medical center
H指数:39
被引数:1.2万

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Astrocyte-derived extracellular vesicle phosphorylated TDP-43 as a blood-based biomarker for amyotrophic lateral sclerosis

星形胶质细胞来源的细胞外囊泡磷酸化TDP-43作为肌萎缩侧索硬化症的血液生物标志物

Neurobiology of Disease
IF5.6
2026-09-100
OAAI
Tanya H. Butt; Madeleine Strait; Lina Marcinczyk; Grace Katz; Vrinda Kalia; Cherine Jaafar; Roheeni Saxena; Adnan Divjan; Brianna Saglimbeni; Marfred E. Munoz Umanes; Eva Tipps; Moon Han; Paul Mehta; Ikjae Lee; Hiroshi Mitsumoto; Pam Factor-Litvak; Neil A. Shneider; Marianthi-Anna Kioumourtzoglou; Diane B. Re
Multiplex neurodegeneration proteotoxicity platform reveals DNAJB6 promotes non-toxic FUS condensate gelation and inhibits neurotoxicity

多通路神经退行性蛋白毒性平台揭示DNAJB6促进非毒性FUS凝聚体凝胶化并抑制神经毒性

Nature Communications
IF15.7
2025-11-210
OAAI
Samuel J. Resnick; Seema Qamar; Pushya Krishna; Vladislav Korobeynikov; Hannes Ausserwoger; Alyssa Miller; Pietro Esposito; Juan A. Varela; Jenny Sheng; Lei Haley Huang; Jonathon Nixon-Abell; Schuyler Melore; Chyi Wei Chung; Nino F. Läubli; Sofia Kapsiani; Xuecong Li; Jingshu Wang; Nancy Zhang; Mahabub Maraj Alam; Alondra S. Burguete; Theresa C. Swayne; Yanyan Chen; Ya-Cheng Liao; Neil A. Shneider; Michele Vendruscolo; Tuomas P. J. Knowles; Clemens F. Kaminski; Francesco Simone Ruggeri; Gabriele S. Kaminski Schierle; Peter St George-Hyslop; Alejandro Chavez
TDP-43-dependent mis-splicing of KCNQ2 triggers intrinsic neuronal hyperexcitability in ALS/FTD

TDP-43依赖性的KCNQ2错位剪接在ALS/FTD中触发内在神经元过度兴奋

Nature Neuroscience
IF20
2025-10-310
OAAI
Brian J. Joseph; Kelly A. Marshall; Peter Harley; Jacob R. Mann; Francesco Alessandrini; Carlos G. Vanoye; Wanhao Chi; Mercedes Prudencio; Dina Simkin; Tzu-Ting Kao; Reshma R. Desai; Matthew J. Keuss; Simone Barattucci; Matteo Zanovello; Puja R. Mehta; Jean-Marc DeKeyser; Francesco Limone; Jonathan Lee; Anna-Leigh Brown; Marcel F. Leyton-Jaimes; Leslie A. Nash; Irune Guerra San Juan; Eleonora Aronica; Brian J. Wainger; Mala Shah; Anand Goswami; Neil A. Shneider; Dennis W. Dickson; Juan Burrone; Chaolin Zhang; Hynek Wichterle; Leonard Petrucelli; Jonathan K. Watts; Alfred L. George; Pietro Fratta; Kevin Eggan; Evangelos Kiskinis
Activation of polo-like kinase 1 correlates with selective motor neuron vulnerability in familial ALS

Polo-like激酶1的活化与家族性ALS中运动神经元的选择性易损性相关。

Cell Reports
IF6.9
2025-08-250
PREAI
Barbara Szewczyk; Vitaly Zimyanin; Julia Japtok; Aaron Held; Arun Pal; Dajana Großmann; Hannes Glaß; Alexandra V. Jürs; Banaja P. Dash; Maciek Bak; Marcel Naumann; Christiane Hartmann; Olena Kuksenko; René Günther; Tzu-Ting Kao; Katrin Sameith; Andreas Dahl; Jared Sterneckert; Eleonora Aronica; Neil A. Shneider; Andreas Büttner; Alberto Catanese; Hemali Phatnani; Markus Kipp; Brian J. Wainger; Anand Goswami; Andreas Hermann
Single-cell transcriptomic landscape of the neuroimmune compartment in amyotrophic lateral sclerosis brain and spinal cord

肌萎缩侧索硬化症大脑和脊髓中神经免疫区域的单细胞转录组景观

Acta Neuropathologica
IF9.3
2025-07-290
OAAI
John F. Tuddenham; Masashi Fujita; Emily Lee; Nivedita Nimmagadda; Anthony Khairallah; Claire Harbison; Xena E. Flowers; Guillermo Coronas-Samano; Silas Maniatis; Aidan Daly; Julie A. Schneider; Andrew F. Teich; Jean Paul G. Vonsattel; Peter A. Sims; Wassim Elyaman; Elizabeth M. Bradshaw; Lyle W. Ostrow; Hemali Phatnani; Neil A. Shneider; David A. Bennett; Philip L. De Jager; Serge Przedborski; Vilas Menon; Marta Olah
Exploring the role of T cells in Alzheimer's and other neurodegenerative diseases: Emerging therapeutic insights from the T Cells in the Brain symposium

探索T细胞在阿尔茨海默病及其他神经退行性疾病中的作用：来自“T Cells in the Brain”研讨会的最新治疗见解

ALZHEIMERS & DEMENTIA
IF11.1
2025-01-271
OAAI
Elyaman, W; Stern, LJ; Jiang, N; Dressman, D; Bradley, P; Klatzmann, D; Bradshaw, EM; Farber, DL; Kent, SC; Chizari, S; Funk, K; Devanand, D; Thakur, KT; Raj, T; Dalahmah, OA; Sarkis, RA; Weiner, HL; Shneider, NA; Przedborski, S
The Miami Framework for ALS and related neurodegenerative disorders: an integrated view of phenotype and biology (May, 10.1038/s41582-024-00961-z, 2024)
NATURE REVIEWS NEUROLOGY
IF33.1
2024-05-290
OA
Benatar, Michael; Wuu, Joanne; Huey, Edward D.; Mcmillan, Corey T.; Petersen, Ronald C.; Postuma, Ronald; McHutchison, Caroline; Dratch, Laynie; Arias, Jalayne J.; Crawley, Anita; Houlden, Henry; McDermott, Michael P.; Cai, Xueya; Thakur, Neil; Boxer, Adam; Rosen, Howard; Boeve, Bradley F.; Dacks, Penny; Cosentino, Stephanie; Abrahams, Sharon; Shneider, Neil; Lingor, Paul; Shefner, Jeremy; Andersen, Peter M.; Al-Chalabi, Ammar; Turner, Martin R.
The Miami Framework for ALS and related neurodegenerative disorders: an integrated view of phenotype and biology
NATURE REVIEWS NEUROLOGY
IF33.1
2024-05-205
OA
Benatar, Michael; Wuu, Joanne; Huey, Edward D.; Mcmillan, Corey T.; Petersen, Ronald C.; Postuma, Ronald; Mchutchison, Caroline; Dratch, Laynie; Arias, Jalayne J.; Crawley, Anita; Houlden, Henry; McDermott, Michael P.; Cai, Xueya; Thakur, Neil; Boxer, Adam; Rosen, Howard; Boeve, Bradley F.; Dacks, Penny; Cosentino, Stephanie; Abrahams, Sharon; Shneider, Neil; Lingor, Paul; Shefner, Jeremy; Andersen, Peter M.; Al-Chalabi, Ammar; Turner, Martin R.; Allred, Peggy; Appel, Stanley; Benatar, David; Berry, James; Bradbury, Meg; Bruijn, Lucie; Buczyner, Jennifer; Carberry, Nathan; Caress, James; Champney, Thomas; Dave, Kuldip; Fradette, Stephanie; Granit, Volkan; Grignon, Anne-Laure; Gubitz, Amelie; Harms, Matthew; Heiman-Patterson, Terry; Hesterlee, Sharon; Lawrence, Karen; Lewis, Travis; Levy, Oren; Lingor, Paul; Mozaffar, Tahseen; Stanislaw, Christine; Thompson, Alexander; Uspenskay, Olga; Weydt, Patrick; Zinman, Lorne
RNA aptamer reveals nuclear TDP-43 pathology is an early aggregation event that coincides with STMN-2 cryptic splicing and precedes clinical manifestation in ALS

RNA适体揭示核TDP-43病理学是早期的聚集事件，与STMN-2的隐性剪接相吻合，并在ALS的临床表现之前

ACTA NEUROPATHOLOGICA
IF9.3
2024-03-053
OA
Spence, Holly; Waldron, Fergal M.; Saleeb, Rebecca S.; Brown, Anna-Leigh; Rifai, Olivia M.; Gilodi, Martina; Read, Fiona; Roberts, Kristine; Milne, Gillian; Wilkinson, Debbie; O'Shaughnessy, Judi; Pastore, Annalisa; Fratta, Pietro; Shneider, Neil; Tartaglia, Gian Gaetano; Zacco, Elsa; Horrocks, Mathew H.; Gregory, Jenna M.
A new approach for rare variation collapsing on functional protein domains implicates specific genic regions in ALS
GENOME RESEARCH
IF5.5
2019-04-0223
OAAI
Gelfman, Sahar; Dugger, Sarah; Moreno, Cristiane de Araujo Martins; Ren, Zhong; Wolock, Charles J.; Shneider, Neil A.; Phatnani, Hemali; Cirulli, Elizabeth T.; Lasseigne, Brittany N.; Harris, Tim; Maniatis, Tom; Rouleau, Guy A.; Brown, Robert H., Jr.; Gitler, Aaron D.; Myers, Richard M.; Petrovski, Slave; Allen, Andrew; Goldstein, David B.; Harms, Matthew B.

研究方向

暂未获取到该数据
A
Aarti Sharma
H 指数:10论文数:14被引数:1,590
H
Hemali Phatnani
H 指数:43论文数:122被引数:1.7万
V
Vladislav A. Korobeynikov
H 指数:10论文数:54被引数:679
A
Alexander K. Lyashchenko
H 指数:5论文数:11被引数:1,004
A
Adam L. Boxer
H 指数:96论文数:610被引数:3.7万
B
Bradley F. Boeve
H 指数:172论文数:1,544被引数:12.9万
C
Corey T. McMillan
H 指数:62论文数:508被引数:1.2万
D
Dennis W. Dickson
H 指数:218论文数:2,307被引数:23.1万
R
Ronald B. Postuma
H 指数:89论文数:433被引数:4.1万
X
Xueya Cai
H 指数:35论文数:156被引数:4,102